Associate Professor of Pediatrics
Contact Info
Phone: (415 ) 502-1691
Email: srinath.sanda@ucsf.edu
Education
- University of California, San Diego, BA, microbiology, 1989-93
- University of California, David, School of Medicine, MD, 1993-97
- Cedars-Sinai Medical Center, residency, internal medicine/pediatrics, 1997-2001
- Cedars-Sinai Medical Center, co-chief resident, internal medicine/pediatrics, 2000-01
- Cedars-Sinai Medical Center, chief resident, pediatrics, 2001-02
- University of California, San Diego, School of Medicine, fellowship, pediatric endocrinology, 2004-07
- La Jolla Institute for Allergy and Immunology, research fellow, Matthias von Herrath Lab, 2004-07
- University of California, San Diego, School of Medicine, CREST program, 2005-07
Board Certification
- Pediatrics. American Board of Pediatrics (2001)
- Internal Medicine, American Board of Internal Medicine (2001)
- Pediatric Endocrinology, American Board of Pediatrics (2007)
Clinical Expertise
- Diabetes
- General pediatric endocrinology
Research Interests
- Immunology of pediatric diabetes
- Genetic factors influencing insulin secretion in pediatric diabetes
UCSF Program Affiliations
- UCSF Diabetes Center
Biography
After completing his residency, Dr. Sanda practiced as a general pediatrician and adult hospitalist in Los Angeles, CA. He then completed a pediatric endocrinology fellowship at UC San Diego with research training in the immunology of type 1 diabetes in the laboratory of Matthias von Herrath. After completing his fellowship, Dr. Sanda took a joint faculty position at the University of Washington/Seattle Children’s Hospital and the Benaroya Research Institute, a national leader in translational research of autoimmune diseases. Dr. Sanda was responsible for enhancing translational immunology research into the pathogenesis of type 1 diabetes, caring for patients in diabetes clinical trials (including immune intervention and artificial pancreas studies), and developing his own clinical and laboratory research projects. He was recently awarded the Mark Pescovitz Early Career Patient Oriented Diabetes Research Award as well as a Career Development Award from the Juvenile Diabetes Research Foundation.
Current Research
Dr. Sanda’s research interests center on the role of the immune system in pediatric diabetes, especially type 1 diabetes. Specifically, he is interested in the role of monocytes and innate inflammatory mediators such as IL-1β in cell migration, beta cell dysfunction, and the development of diabetes-related complications. These pathways may also be active in other forms of pediatric diabetes such as type 2 diabetes and cystic fibrosis-related diabetes (CFRD). Dr. Sanda’s lab analyzes human blood samples from patients with and without diabetes to understand the mechanisms of monocyte biology and to develop biomarkers useful in immune intervention trials for type 1 diabetes.
In addition, Dr. Sanda has begun to study genetic factors responsible for insulin secretion in type 1 diabetes. Specifically he has identified a genetic variant in the gene G6PC2 that may correlate with decline in insulin secretion over time in type 1 diabetes. Dr. Sanda plans to continue these preliminary studies by analyzing larger cohorts and conducting a broader analysis of genetic variants.