UCSF is one of the world’s leading centers for biomedical research. Faculty within the division conduct state-of-the-art research in childhood leukemias, brain tumors, sacrcomas, and neuroblastomas. Major efforts involve investigating the genetic basis of pediatric malignancies, the development of accurate mouse models of these cancers, the use of novel, biologically targeted agents in preclinical animal models and human patients, and developing innovative clinical interventions and ways of monitoring disease response. The division also has an active precision medicine program and a major effort to perform integrative genomics for high-risk pediatric cancers. An active COG phase I program also provides opportunities for trainees interested in clinical research.

Basic/Translational research labs in pediatric oncology at UCSF:

Gustafson Laboratory New therapeutic development and clinical translation in cancer requires a solid understanding of basic tumor biology.	Loh Laboratory The mission of the laboratory is to study primary patient leukemia samples in order to identify novel genetic alterations ...
Sabnis Laboratory The Sabnis laboratory is investigating selective vulnerabilities in the way cancer cells choose to build, fold, and destroy their constituent proteins.	Shannon Laboratory Nature is nowhere accustomed more openly to display her secret mysteries than in cases where she shows tracings of her workings
Stieglitz Laboratory The mission of our lab is to improve outcomes for children with Ras-driven leukemia	Sweetcordero Laboratory Our goal is to identify novel therapeutic approaches for cancer that target the genetic mutations ...