Amy Gelfand
Associate Professor
UCSF Weill Institute for Neurosciences
+1 415 502-1914
+1 415 353-9539


Dr. Amy Gelfand is a board-certified child neurologist and Director of Pediatric Headache at UCSF. She specializes in diagnosing and treating children who suffer from a variety of headache disorders, as well as children with childhood periodic syndromes such as abdominal migraine that may be precursors to migraine headache later in life. Her research focuses on the epidemiology and treatment of pediatric migraine and childhood periodic syndromes.

Gelfand received her medical degree from Harvard Medical School. Subsequently, she completed a residency in pediatrics and residency in child neurology at UCSF, then subspecialty fellowship training in pediatric headache at UCSF.

She is the recipient of a teaching award from the UCSF Pediatrics Residents and writing awards from the Resident and Fellows Section of the medical journal, Neurology. Gelfand is a member of the American Academy of Neurology, Child Neurology Society, American Headache Society and International Headache Society.

She is the Principal Investigator of the BRAiN-M Study (Bringing Relief to Adolescents Naturally using Melatonin):

Education and Training

Cert, 2013 Medicine (Advance Training in Clinical Research), University of California, San Francisco
M.D., 2006 School of Medicine, Harvard University
Residency, School of Medicine, University of California, San Francisco


Greene KA, Lu V, Luciano MS, Qubty W, Irwin SL, Grimes B, Gelfand AA. Benign paroxysmal torticollis: phenotype, natural history, and quality of life. Pediatr Res. 2021 Feb 09.
Gelfand AA, Poland G. Migraine treatment and COVID-19 vaccines: no cause for concern. Headache. 2021 Feb 05.
Gelfand AA, Ross AC, Pavitt S, Szperka CL, Irwin SL, Bertisch S, Stone KL, Frazier R, Grimes B, Allen IE. Would chronotype change the impact of the relationship between early school schedules and adolescent migraine frequency? A response. Headache. 2021 Feb 05.
Gelfand AA. Headache refresh 2021. Headache. 2021 Jan; 61(1):1.
Gelfand AA, Goadsby PJ. Treating Migraine in Children and Adolescents. JAMA Pediatr. 2021 Jan 01; 175(1):102.
Gelfand AA, Pavitt S, Ross AC, Szperka CL, Irwin SL, Bertisch S, Stone KL, Frazier R, Grimes B, Allen IE. Later high school start time is associated with lower migraine frequency in adolescents. Headache. 2020 Nov 25.
Cabana MD, Wright P, Scozzafava I, Olarte A, DiSabella M, Liu X, Gelfand AA. Newborn Daily Crying Time Duration. J Pediatr Nurs. 2021 Jan-Feb; 56:35-37.
Greene KA, Gentile CP, Szperka CL, Yonker M, Gelfand AA, Grimes B, Irwin SL. Calcitonin Gene-Related Peptide Monoclonal Antibody Use for the Preventive Treatment of Refractory Headache Disorders in Adolescents. Pediatr Neurol. 2020 Oct 05; 114:62-67.
Orr SL, Gelfand AA, Hranilovich J, Irwin SL, Kabbouche M, Lagman-Bartolome AM, Lavell C, O'Brien HL, Rajapakse T, Rao R, Szperka C, Werner K, VanderPluym J, Yonker M, Hershey A. The Development of the Medical Transfer Packet for Transition of Care of the Pediatric Patient with Headache. Headache. 2020 Nov; 60(10):2589-2591.
Gelfand AA, Ross AC, Irwin SL, Greene KA, Qubty WF, Allen IE. Melatonin for Acute Treatment of Migraine in Children and Adolescents: A Pilot Randomized Trial. Headache. 2020 Sep; 60(8):1712-1721.
Gelfand AA, Irwin SL. Lifestyle Advice for Pediatric Migraine: Blaming the Patient, or Evidence Based? Semin Neurol. 2020 06; 40(3):277-285.
VanderPluym J, Gautreaux J, Burch R, Whitaker E, Roberts J, Turner DP, Gelfand AA. Evidence Regarding Medication Overuse Headache in Children and Adolescents: Protocol for a Systematic Review. Headache. 2020 01; 60(1):171-177.
Szperka CL, Gelfand AA. Recommendations on the Use of Anti-CGRP Monoclonal Antibodies in Children and Adolescents - A Comment. Headache. 2020 01; 60(1):273.
Hornik CP, Gelfand AA, Szperka CL, Pezzuto T, Utevsky A, Kessel S, McCune S, Alexander JJ, Benjamin DK, Cohen-Wolkowiez M. Development of a Prospective Real-World Data Clinical Registry of Children and Adolescents With Migraine. Headache. 2020 02; 60(2):405-415.
Turner SB, Rende EK, Pezzuto T, Weaver S, Henderlong-Kropp A, Greene KA, Bicknese AR, Dilts JJ, Gautreaux J, Victorio MCC, Strauss LD, Lagman-Bartolome AM, Szperka CL, Yonker M, Hershey AD, Gelfand AA. Pediatric Migraine Action Plan (PedMAP). Headache. 2019 11; 59(10):1871-1873.
Turner SB, Rende EK, Szperka CL, Hershey AD, Gelfand AA. The Development of the Pediatric Migraine Action Plan (PedMAP). Headache. 2019 11; 59(10):1671-1672.
Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GA, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR. Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nat Med. 2019 11; 25(11):1748-1752.
LaHue SC, Gelfand AA, Bove RM. Navigating monoclonal antibody use in breastfeeding women: Do no harm or do little good? Neurology. 2019 10 08; 93(15):668-672.
Hershey AD, Oskoui M, Pringsheim T, Holler-Managan Y, Potrebic S, Billinghurst L, Gloss D, Licking N, Sowell M, Victorio MC, Gersz E, Vrijsen E, Zanitsch H, Yonker M, Mack K, Gelfand AA, Szperka CL, Powers SW. New Guidelines: Interpretation, Application and the Future. Headache. 2019 09; 59(8):1133-1143.
Greene K, Irwin SL, Gelfand AA. Pediatric Migraine: An Update. Neurol Clin. 2019 11; 37(4):815-833.
Gelfand AA, Buse DC, Cabana MD, Grimes B, Goadsby PJ, Allen IE. The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study. Headache. 2019 07; 59(7):988-1001.
Hall AL, Karvounides D, Gelfand AA, Mankin H, Kessel S, Corroo J, Malavolta CP, Pezzuto T, Chadehumbe M, Szperka CL. Improving the Patient Experience With Migraine Camp, a One-Day Group Intervention for Adolescents With Chronic Headache and Their Parents. Headache. 2019 09; 59(8):1392-1400.
Berger A, Litwin J, Allen IE, Qubty W, Irwin S, Waung M, Gelfand AA. Preliminary Evidence that Melatonin Is not a Biomarker in Children and Adolescents With Episodic Migraine. Headache. 2019 07; 59(7):1014-1023.
Gelfand AA, Pavitt S, Greene K, Szperka CL, Irwin S, Grimes B, Allen IE. High School Start Time and Migraine Frequency in High School Students. Headache. 2019 07; 59(7):1024-1031.
Gelfand AA, Loder E. Potential Benefits of Migraine-What Is It Good For? JAMA Neurol. 2019 03 01; 76(3):250-251.
Seng EK, Gelfand AA, Nicholson RA. Assessing evidence-based medicine and opioid/barbiturate as first-line acute treatment of pediatric migraine and primary headache: A retrospective observational study of health systems data. Cephalalgia. 2019 Jul; 39(8):1000-1009.
Szperka CL, VanderPluym J, Orr SL, Oakley CB, Qubty W, Patniyot I, Lagman-Bartolome AM, Morris C, Gautreaux J, Victorio MC, Hagler S, Narula S, Candee MS, Cleves-Bayon C, Rao R, Fryer RH, Bicknese AR, Yonker M, Hershey AD, Powers SW, Goadsby PJ, Gelfand AA. Recommendations on the Use of Anti-CGRP Monoclonal Antibodies in Children and Adolescents. Headache. 2018 11; 58(10):1658-1669.
Gelfand AA, Goadsby PJ. Cluster Headache and Calcitonin Gene-Related Peptide-More on Quantum Therapeutics in Headache Medicine. JAMA Neurol. 2018 10 01; 75(10):1179-1180.
Gelfand AA. Pediatric and Adolescent Headache. Continuum (Minneap Minn). 2018 08; 24(4, Headache):1108-1136.
Irwin SL, Gelfand AA. Occipital Headaches and Neuroimaging in Children. Curr Pain Headache Rep. 2018 Jul 10; 22(9):59.
Gelfand AA. Episodic syndromes of childhood associated with migraine. Curr Opin Neurol. 2018 06; 31(3):281-285.
Dodick DW, Tepper SJ, Friedman DI, Gelfand AA, Kellerman DJ, Schmidt PC. Use of Most Bothersome Symptom as a Coprimary Endpoint in Migraine Clinical Trials: A Post-Hoc Analysis of the Pivotal ZOTRIP Randomized, Controlled Trial. Headache. 2018 Jul; 58(7):986-992.
Qubty W, Patniyot I, Gelfand A. Telemedicine in a pediatric headache clinic: A prospective survey. Neurology. 2018 05 08; 90(19):e1702-e1705.
Gelfand JM, Gelfand AA, Goadsby PJ, Benn BS, Koth LL. Migraine is common in patients with sarcoidosis. Cephalalgia. 2018 12; 38(14):2079-2082.
Irwin SL, Qubty W, Allen IE, Patniyot I, Goadsby PJ, Gelfand AA. Transcranial Magnetic Stimulation for Migraine Prevention in Adolescents: A Pilot Open-Label Study. Headache. 2018 May; 58(5):724-731.
Starling AJ, Tepper SJ, Marmura MJ, Shamim EA, Robbins MS, Hindiyeh N, Charles AC, Goadsby PJ, Lipton RB, Silberstein SD, Gelfand AA, Chiacchierini RP, Dodick DW. A multicenter, prospective, single arm, open label, observational study of sTMS for migraine prevention (ESPOUSE Study). Cephalalgia. 2018 05; 38(6):1038-1048.
Buse DC, Powers SW, Gelfand AA, VanderPluym JH, Fanning KM, Reed ML, Adams AM, Lipton RB. Adolescent Perspectives on the Burden of a Parent's Migraine: Results from the CaMEO Study. Headache. 2018 Apr; 58(4):512-524.
Özge A, Abu-Arafeh I, Gelfand AA, Goadsby PJ, Cuvellier JC, Valeriani M, Sergeev A, Barlow K, Uludüz D, Yalin OÖ, Faedda N, Lipton RB, Rapoport A, Guidetti V. Experts' opinion about the pediatric secondary headaches diagnostic criteria of the ICHD-3 beta. J Headache Pain. 2017 Nov 29; 18(1):113.
Özge A, Faedda N, Abu-Arafeh I, Gelfand AA, Goadsby PJ, Cuvellier JC, Valeriani M, Sergeev A, Barlow K, Uludüz D, Yalin OÖ, Lipton RB, Rapoport A, Guidetti V. Experts' opinion about the primary headache diagnostic criteria of the ICHD-3rd edition beta in children and adolescents. J Headache Pain. 2017 Nov 23; 18(1):109.
Gelfand AA, Qubty W, Goadsby PJ. Pediatric Migraine Prevention-First, Do No Harm. JAMA Neurol. 2017 08 01; 74(8):893-894.
Bear JJ, Gelfand AA, Goadsby PJ, Bass N. Occipital headaches and neuroimaging in children. Neurology. 2017 Aug 01; 89(5):469-474.
Tso AR, Patniyot IR, Gelfand AA, Goadsby PJ. Increased rate of venous thrombosis may be associated with inpatient dihydroergotamine treatment. Neurology. 2017 Jul 18; 89(3):279-283.
Gelfand AA, Qubty W, Patniyot I, Grimes B, Pletcher MJ, Goadsby PJ, Cummings SR. Home-Based Trials in Adolescent Migraine: A Randomized Clinical Trial. JAMA Neurol. 2017 06 01; 74(6):744-745.
Gelfand AA. Melatonin in the Treatment of Primary Headache Disorders. Headache. 2017 06; 57(6):848-849.
Gelfand AA. Acupuncture for Migraine Prevention: Still Reaching for Convincing Evidence. JAMA Intern Med. 2017 04 01; 177(4):516-517.
Irwin S, Barmherzig R, Gelfand A. Recurrent Gastrointestinal Disturbance: Abdominal Migraine and Cyclic Vomiting Syndrome. Curr Neurol Neurosci Rep. 2017 03; 17(3):21.
Gelfand AA, Johnson H, Lenaerts ME, Litwin JR, De Mesa C, Bogduk N, Goadsby PJ. Neck-Tongue syndrome: A systematic review. Cephalalgia. 2018 02; 38(2):374-382.
Qubty W, Gelfand AA. Psychological and Behavioral Issues in the Management of Migraine in Children and Adolescents. Curr Pain Headache Rep. 2016 Dec; 20(12):69.
Szperka CL, Gelfand AA, Hershey AD. Patterns of Use of Peripheral Nerve Blocks and Trigger Point Injections for Pediatric Headache: Results of a Survey of the American Headache Society Pediatric and Adolescent Section. Headache. 2016 Nov; 56(10):1597-1607.
Gelfand AA, Goadsby PJ. The Role of Melatonin in the Treatment of Primary Headache Disorders. Headache. 2016 Sep; 56(8):1257-66.
Qubty W, Gelfand AA. The Link Between Infantile Colic and Migraine. Curr Pain Headache Rep. 2016 May; 20(5):31.
Johnson HF, Goadsby PJ, Gelfand AA. Predictors of Triptan Response in Pediatric Migraine. Pediatr Neurol. 2016 05; 58:37-40.
Eller M, Gelfand AA, Riggins NY, Shiboski S, Schankin C, Goadsby PJ. Exacerbation of headache during dihydroergotamine for chronic migraine does not alter outcome. Neurology. 2016 Mar 01; 86(9):856-9.
Patniyot IR, Gelfand AA. Acute Treatment Therapies for Pediatric Migraine: A Qualitative Systematic Review. Headache. 2016 Jan; 56(1):49-70.
Qubty W, Gelfand AA. Review of Prevention for Pediatric and Adolescent Migraine. Pediatr Neurol Briefs. 2016 Jan; 30(1):5.
Gelfand AA, Gallagher RC. Cyclic vomiting syndrome versus inborn errors of metabolism: A review with clinical recommendations. Headache. 2016 Jan; 56(1):215-21.
Gelfand AA. Infant Colic. Semin Pediatr Neurol. 2016 Feb; 23(1):79-82.
Gelfand AA. Episodic Syndromes That May Be Associated With Migraine: A.K.A. "the Childhood Periodic Syndromes". Headache. 2015 Nov-Dec; 55(10):1358-64.
Pressman A, Jacobson A, Eguilos R, Gelfand A, Huynh C, Hamilton L, Avins A, Bakshi N, Merikangas K. Prevalence of migraine in a diverse community--electronic methods for migraine ascertainment in a large integrated health plan. Cephalalgia. 2016 Apr; 36(4):325-34.
Gelfand AA. Psychiatric comorbidity and paediatric migraine: examining the evidence. Curr Opin Neurol. 2015 Jun; 28(3):261-4.
Gelfand AA, Fullerton HJ, Jacobson A, Sidney S, Goadsby PJ, Kurth T, Pressman A. Is migraine a risk factor for pediatric stroke? Cephalalgia. 2015 Dec; 35(14):1252-60.
Gelfand AA. Infant colic--a baby's migraine? Cephalalgia. 2015 Dec; 35(14):1243-5.
Gelfand AA. Migraine in young children. Dev Med Child Neurol. 2015 Jun; 57(6):503.
Gelfand AA, Goadsby PJ. Medication overuse in children and adolescents. Curr Pain Headache Rep. 2014 Jul; 18(7):428.
Gelfand AA, Goadsby PJ, Allen IE. The relationship between migraine and infant colic: a systematic review and meta-analysis. Cephalalgia. 2015 Jan; 35(1):63-72.
Young-Lin N, Shalev S, Glenn OA, Gardner M, Lee C, Wynshaw-Boris A, Gelfand AA. Teaching neuroimages: infant with glutaric aciduria type 1 presenting with infantile spasms and hypsarrhythmia. Neurology. 2013 Dec 10; 81(24):e182-3.
Gelfand AA, Reider AC, Goadsby PJ. Outcomes of greater occipital nerve injections in pediatric patients with chronic primary headache disorders. Pediatr Neurol. 2014 Feb; 50(2):135-9.
Gelfand AA. Childhood migraine is associated with a history of infantile colic. J Pediatr. 2013 Sep; 163(3):922-3.
Gelfand AA, Reider AC, Goadsby PJ. Cranial autonomic symptoms in pediatric migraine are the rule, not the exception. Neurology. 2013 Jul 30; 81(5):431-6.
Gelfand AA. Migraine and childhood periodic syndromes in children and adolescents. Curr Opin Neurol. 2013 Jun; 26(3):262-8.
Gelfand AA, Gelfand JM, Goadsby PJ. Migraine and multiple sclerosis: Epidemiology and approach to treatment. Mult Scler Relat Disord. 2013 Apr; 2(2):73-9.
Gelfand AA, Croen LA, Torres AR, Wu YW. Genetic risk factors for perinatal arterial ischemic stroke. Pediatr Neurol. 2013 Jan; 48(1):36-41.
Gelfand AA, Goadsby PJ. Treatment of pediatric migraine in the emergency room. Pediatr Neurol. 2012 Oct; 47(4):233-41.
Gelfand AA, Thomas KC, Goadsby PJ. Before the headache: infant colic as an early life expression of migraine. Neurology. 2012 Sep 25; 79(13):1392-6.
Gelfand AA, Goadsby PJ. Primary sex headache in adolescents. Pediatrics. 2012 Aug; 130(2):e439-41.
Gelfand AA, Goadsby PJ. A Neurologist's Guide to Acute Migraine Therapy in the Emergency Room. Neurohospitalist. 2012 Apr 01; 2(2):51-59.
Gelfand AA, Gelfand JM, Prabakhar P, Goadsby PJ. Ophthalmoplegic "migraine" or recurrent ophthalmoplegic cranial neuropathy: new cases and a systematic review. J Child Neurol. 2012 Jun; 27(6):759-66.
Wu YW, Croen LA, Vanderwerf A, Gelfand AA, Torres AR. Candidate genes and risk for CP: a population-based study. Pediatr Res. 2011 Dec; 70(6):642-6.
Pham CB, Kratz JR, Jelin AC, Gelfand AA. Child neurology: Brachial plexus birth injury: what every neurologist needs to know. Neurology. 2011 Aug 16; 77(7):695-7.
Gelfand AA, Sznewajs A, Glass HC, Jelin AC, Sherr EH. Clinical Reasoning: An encephalopathic 3-day-old infant. Neurology. 2011 Jul 05; 77(1):e1-5.
Gelfand AA. Right brain: we were all once "fixed and dilated". Neurology. 2010 Nov 16; 75(20):1851-2.
Gelfand AA, Fullerton HJ, Goadsby PJ. Child neurology: Migraine with aura in children. Neurology. 2010 Aug 03; 75(5):e16-9.
Gelfand AA, Josephson SA. Substantial radiation exposure for patients with subarachnoid hemorrhage. J Stroke Cerebrovasc Dis. 2011 Mar-Apr; 20(2):131-3.
Gelfand AA. A piece of my mind. Triggers. JAMA. 2006 Sep 13; 296(10):1211-2.
Högenauer C, Santa Ana CA, Porter JL, Millard M, Gelfand A, Rosenblatt RL, Prestidge CB, Fordtran JS. Active intestinal chloride secretion in human carriers of cystic fibrosis mutations: an evaluation of the hypothesis that heterozygotes have subnormal active intestinal chloride secretion. Am J Hum Genet. 2000 Dec; 67(6):1422-7.