Atovaquone is active against AML by upregulating the integrated stress pathway and suppressing oxidative phosphorylation.

Stevens AM, Xiang M, Heppler LN, Tošic I, Jiang K, Munoz JO, Gaikwad AS, Horton TM, Long X, Narayanan P, Seashore EL, Terrell MC, Rashid R, Krueger MJ, Mangubat-Medina AE, Ball ZT, Sumazin P, Walker SR, Hamada Y, Oyadomari S, Redell MS, Frank DA