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FET Fusion Oncoproteins Disrupt Physiologic DNA Repair and Create a Targetable Opportunity for ATR Inhibitor Therapy.
Editor's Note: Inhibition of Phosphatidylinositol 3-Kinase Destabilizes Mycn Protein and Blocks Malignant Progression in Neuroblastoma.
ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma.
ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma.
Abstract 1509: Longitudinal profiling of high-risk pediatric malignancies using a multiomics approach.
Wnt Signaling in the Phenotype and Function of Tumor-Associated Macrophages.
N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma.
Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis.
Abstract 54: Integrative analysis of whole-genome and RNA sequencing in high-risk pediatric malignancies.
Abstract CT015: A phase 1 dose escalation study of TB-403 in pediatric relapsed or refractory medulloblastoma, neuroblastoma, Ewing sarcoma, or alveolar rhabdomyosarcoma.