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Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma.
A dual phosphoinositide-3-kinase alpha/mTOR inhibitor cooperates with blockade of epidermal growth factor receptor in PTEN-mutant glioma.
Inhibition of phosphatidylinositol 3-kinase destabilizes Mycn protein and blocks malignant progression in neuroblastoma.
Integrative genomics identifies distinct molecular classes of neuroblastoma and shows that multiple genes are targeted by regional alterations in DNA copy number.
Shared epigenetic mechanisms in human and mouse gliomas inactivate expression of the growth suppressor SLC5A8.
Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis.
Combinatorial efficacy achieved through two-point blockade within a signaling pathway-a chemical genetic approach.
Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors.
Genetic determinants of malignancy in a mouse model for oligodendroglioma.
Bcl-2 overexpression results in enhanced capacitative calcium entry and resistance to SKF-96365-induced apoptosis.