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Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.
Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism.
RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor.
Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase.
Loss of murine Na+/myo-inositol cotransporter leads to brain myo-inositol depletion and central apnea.
Transforming growth factor-beta inhibits pulmonary surfactant protein B gene transcription through SMAD3 interactions with NKX2.1 and HNF-3 transcription factors.
Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity.
The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes.
Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3.
Phorbol ester down-regulation of lung surfactant protein B gene expression by cytoplasmic trapping of thyroid transcription factor-1 and hepatocyte nuclear factor 3.