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AF1q is a universal marker of neuroblastoma that sustains N-Myc expression and drives tumorigenesis.
Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma.
Epidermal growth factor receptor and EGFRvIII in glioblastoma: signaling pathways and targeted therapies.
Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.
RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines.
Alternative splicing in cancer: implications for biology and therapy.
Upregulation of the microRNA cluster at the Dlk1-Dio3 locus in lung adenocarcinoma.
Myc proteins as therapeutic targets.
Cyclic GMP-dependent protein kinase II inhibits cell proliferation, Sox9 expression and Akt phosphorylation in human glioma cell lines.
RNA interference against a glioma-derived allele of EGFR induces blockade at G2M.