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LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival.
Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder.
Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis.
Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp.
Genome-wide DNA methylation is predictive of outcome in juvenile myelomonocytic leukemia.
A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue.
An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.
Identification of proliferative progenitors associated with prominent postnatal growth of the pons.
KRAS insertion mutations are oncogenic and exhibit distinct functional properties.
Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation.