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Age-of-diagnosis dependent ileal immune intensification and reduced alpha-defensin in older versus younger pediatric Crohn Disease patients despite already established dysbiosis.
ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner.
Abnormal apical-to-basal transport of dietary ovalbumin by secretory IgA stimulates a mucosal Th1 response.
Multiple facets of intestinal permeability and epithelial handling of dietary antigens.
Celiac disease: from oral tolerance to intestinal inflammation, autoimmunity and lymphomagenesis.