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Mitochondrial retention and autophagy dysregulation drive oxidative stress in sickle cell disease erythrocytes.

  • Read more about Mitochondrial retention and autophagy dysregulation drive oxidative stress in sickle cell disease erythrocytes.

Reticulocyte mitochondrial retention increases reactive oxygen species and oxygen consumption in mouse models of sickle cell disease and phlebotomy-induced anemia.

  • Read more about Reticulocyte mitochondrial retention increases reactive oxygen species and oxygen consumption in mouse models of sickle cell disease and phlebotomy-induced anemia.

Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons.

  • Read more about Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons.

Dysregulation of the transcription factor runx1 in juvenile myelomonocytic leukemia.

  • Read more about Dysregulation of the transcription factor runx1 in juvenile myelomonocytic leukemia.

Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study.

  • Read more about Clonal evolution in marrows of patients with Shwachman-Diamond syndrome: a prospective 5-year follow-up study.

Interleukin-7R alpha mRNA expression increases as stem cells differentiate into T and B lymphocyte progenitors.

  • Read more about Interleukin-7R alpha mRNA expression increases as stem cells differentiate into T and B lymphocyte progenitors.

Evidence for a heterogeneous response to erythropoietin in the CFUE pool of human bone marrow.

  • Read more about Evidence for a heterogeneous response to erythropoietin in the CFUE pool of human bone marrow.
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