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Coordinated immune dysregulation in Juvenile Dermatomyositis revealed by single-cell genomics.
TBXT dose sensitivity and the decoupling of nascent mesoderm specification from EMT progression in 2D human gastruloids.
Modulating the Unfolded Protein Response with ISRIB Mitigates Cisplatin Ototoxicity.
Structural and molecular basis of choline uptake into the brain by FLVCR2.
Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity.
Radial glia promote microglial development through integrin α V β 8 -TGFβ1 signaling.
PRDM6 promotes medulloblastoma by repressing chromatin accessibility and altering gene expression.
NOTCH3 drives meningioma tumorigenesis and resistance to radiotherapy.
TOMM40 and TOMM22 of the Translocase Outer Mitochondrial Membrane Complex rescue statin-impaired mitochondrial dynamics, morphology, and mitophagy in skeletal myotubes.
Participant-derived cell line transcriptomic analyses and mouse studies reveal a role for ZNF335 in plasma cholesterol statin response.