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Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.
IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease.
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis.
Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow.
The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction.
Members of the HRT family of basic helix-loop-helix proteins act as transcriptional repressors downstream of Notch signaling.
Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation.
Assessment of the allosteric mechanism of aspartate transcarbamoylase based on the crystalline structure of the unregulated catalytic subunit.
Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.