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Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects.
Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure.
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling.
Activation of hypoxia-inducible factors in hyperoxia through prolyl 4-hydroxylase blockade in cells and explants of primate lung.
Mechanisms of embryonal tumor initiation: distinct roles for MycN expression and MYCN amplification.
Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder.
IL-3 receptor signaling is dispensable for BCR-ABL-induced myeloproliferative disease.
High incidence of epithelial cancers in mice deficient for DNA polymerase delta proofreading.
GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis.
Drug selection with paclitaxel restores expression of linked IL-2 receptor gamma -chain and multidrug resistance (MDR1) transgenes in canine bone marrow.