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Discovery of VH domains that allosterically inhibit ENPP1.

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ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.

  • Read more about ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.

  • Read more about Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases.

Recognizing and exploiting differences between RNAi and small-molecule inhibitors.

  • Read more about Recognizing and exploiting differences between RNAi and small-molecule inhibitors.

Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.

  • Read more about Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.
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