Emin Maltepe, MD, PhD

  1. Jonathan Hyde, Michael Smith, Naveen Swami, Gary Raff, Yen-Chen Chao, Johnny Hwang, Jason Boehme, Sanjeev Datar, Emin Maltepe, Jeffrey Fineman. Abstract 4372620: Pulmonary Vascular Endothelial Dysfunction is Induced by Non-Pulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model. Circulation 2025. PMID:


  2. Smith MA, Guardado ES, Boehme J, Datar SA, Maltepe E, Swami N, Raff GW, Bodansky A, Chelladurai P, Moreno J, Prince AR, Powers N, Huang GN, de Jesus Perez V, Fineman JR. Microvascular preservation & cardiomyocyte hyperplasia underlie adaptive right ventricle development in congenital heart disease-pulmonary arterial hypertension. American journal of physiology. Heart and circulatory physiology 2025. PMID: 40924618


  3. Oqani RK, Maltepe E, Rinaudo P, Wagner DE. Mouse placentae generated by in vitro fertilization exhibit altered gene expression, activated hypoxia responses and reduced fitness†. Biology of reproduction 2025. PMID: 40874534


  4. Yegambaram M, Sun X, Lu Q, Flores AG, Zemskova M, Soto J, Rauckhorst A, Maltepe E, Wang T, Fineman JR, Black SM. c-Myc promotes metabolic reprogramming in pulmonary hypertension via the stimulation of glutaminolysis and the reductive tricarboxylic acid cycle. Redox biology 2025. PMID: 40680382


  5. Boehme JT, Datar SA, Sun X, Gong W, Lu Q, Soto J, Smith MA, Garcia-Flores AE, Raff GW, Wang T, Maltepe E, Black SM, Fineman JR. Mechanotransductive stabilization of HIF-1α is inhibited by mitochondrial antioxidant therapy in the setting of pulmonary overcirculation. Scientific Reports 2025. PMID: 40348934


  6. Yegambaram M, Pokharel MD, Sun X, Lu Q, Soto J, Aggarwal S, Maltepe E, Fineman JR, Wang T, Black SM. Restoration of pp60Src Re-Establishes Electron Transport Chain Complex I Activity in Pulmonary Hypertensive Endothelial Cells. International journal of molecular sciences 2025. PMID: 40332450


  7. Mike JK, White Y, Ha J, Iranmahboub A, Hawkins C, Hutchings RS, Vento C, Manzoor H, Wang A, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Fineman JR, Ferriero DM, Maltepe E. Perinatal Caffeine Administration Improves Outcomes in an Ovine Model of Neonatal Hypoxia-Ischemia. Stroke 2024. PMID: 39429154


  8. Tsoi SM, Steurer M, Maltepe E, Fineman JR. Pre-eclampsia and barker's hypothesis: are we beginning to see the trees within the forest? Pediatric research 2024. PMID: 38822134


  9. Maltepe E, Smith M, Boehme J, Datar SA, Hutchings RS, Vento CA, Manzoor H, Loucks A, Winger JA, Fineman JR. OMX: A Novel Oxygen Delivery Biotherapeutic Improves Outcomes in an Ovine Model of Controlled Hemorrhagic Shock. Shock (Augusta, Ga.) 2024. PMID: 38662597


  10. Sharma M, Fineman DC, Keller RL, Maltepe E, Rinaudo PF, Steurer MA. The effect of fertility treatment and socioeconomic status on neonatal and post-neonatal mortality in the United States. Journal of perinatology : official journal of the California Perinatal Association 2024. PMID: 38212435


  11. EMIN MALTEPE, ANNA A. PENN. 3 Development, Function, and Pathology of the Placenta. Avery's Diseases of the Newborn 2024. PMID:


  12. Mike JK, White Y, Hutchings RS, Vento C, Ha J, Iranmahboub A, Manzoor H, Gunewardena A, Cheah C, Wang A, Goudy BD, Lakshminrusimha S, Long-Boyle J, Fineman JR, Ferriero DM, Maltepe E. Effect of Clemastine on Neurophysiological Outcomes in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy. Children (Basel, Switzerland) 2023. PMID: 38002819


  13. Mike JK, White Y, Hutchings RS, Vento C, Ha J, Manzoor H, Lee D, Losser C, Arellano K, Vanhatalo O, Seifert E, Gunewardena A, Wen B, Wang L, Wang A, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Wu YW, Fineman JR, Ferriero DM, Maltepe E. Perinatal Azithromycin Provides Limited Neuroprotection in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy. Stroke 2023. PMID: 37846563


  14. Sabir H, Maes E, Zweyer M, Schleehuber Y, Imam FB, Silverman J, White Y, Pang R, Pasca AM, Robertson NJ, Maltepe E, Bernis ME. Comparing the efficacy in reducing brain injury of different neuroprotective agents following neonatal hypoxia-ischemia in newborn rats: a multi-drug randomized controlled screening trial. Scientific Reports 2023. PMID: 37301929


  15. Fineman DC, Keller RL, Maltepe E, Rinaudo PF, Steurer MA. Fertility treatment increases the risk of preterm birth independent of multiple gestations. F&S Reports 2023. PMID: 37719103


  16. Ying Liang, Wojciech Ornatowski, Qing Lu, Xutong Sun, Alejandro E Garcia, Evgeny A Zemskov, Emin Maltepe, Jeffrey R Fineman, Kim Tieu, Ting Wang, Stephen M Black. Abstract 13625: Autophagy Plays a Key Role in the Loss of Nitric Oxide Signaling and Endothelial Dysfunction in Pulmonary Vascular Diseases. Circulation 2022. PMID:


  17. Redline RW, Roberts DJ, Parast MM, Ernst LM, Morgan TK, Greene MF, Gyamfi-Bannerman C, Louis JM, Maltepe E, Mestan KK, Romero R, Stone J. Placental pathology is necessary to understand common pregnancy complications and achieve an improved taxonomy of obstetrical disease. American journal of obstetrics and gynecology 2022. PMID: 35973475


  18. Mike JK, Wu KY, White Y, Pathipati P, Ndjamen B, Hutchings RS, Losser C, Vento C, Arellano K, Vanhatalo O, Ostrin S, Windsor C, Ha J, Alhassen Z, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JV, Long-Boyle J, Chen P, Wu YW, Fineman JR, Ferriero DM, Maltepe E. Defining longer term outcomes in an ovine model of moderate perinatal hypoxia-ischemia. 2022. PMID: 35588703


  19. Wojciech Ornatowski, Qing Lu, Xutong Sun, Alejandro Garcia Flores, Anlin Feng, Evgeny Zemskov, Emin Maltepe, Jeffrey Fineman, Ting Wang, Stephen Black. Autophagy plays a key role in hyper-proliferative phenotype in pulmonary vascular diseases. Free Radical Biology and Medicine 2022. PMID:


  20. Jason Boehme, Emin Maltepe. Cellular Oxygen Sensing, Mitochondrial Oxygen Sensing and Reactive Oxygen Species. 2021. PMID:


  21. Fineman DC, Keller RL, Maltepe E, Rinaudo PF, Steurer MA. Outcomes of Very Preterm Infants Conceived with Assisted Reproductive Technologies. The Journal of pediatrics 2021. PMID: 34023343


  22. Sonmezoglu S, Fineman JR, Maltepe E, Maharbiz MM. Monitoring deep-tissue oxygenation with a millimeter-scale ultrasonic implant. Nature biotechnology 2021. PMID: 33782610


  23. Boehme JT, Morris CJ, Chiacchia SR, Gong W, Wu KY, Kameny RJ, Raff GW, Fineman JR, Maltepe E, Datar SA. HIF-1a promotes cellular growth in lymphatic endothelial cells exposed to chronically elevated pulmonary lymph flow. Scientific Reports 2021. PMID: 33446832


  24. Ruggeri E, Lira-Albarrán S, Grow EJ, Liu X, Harner R, Maltepe E, Ramalho-Santos M, Donjacour A, Rinaudo P. Sex-specific epigenetic profile of inner cell mass of mice conceived in vivo or by IVF. Molecular human reproduction 2020. PMID: 33010164


  25. Xiao Z, Donjacour A, Harner R, Simbulan R, Kao CN, Ruggeri E, Liu X, Maltepe E, Rinaudo P. Effect of culture conditions and method of conception on mouse live birth rate. 2020. PMID: 35559924


  26. Bennett NK, Nguyen MK, Darch MA, Nakaoka HJ, Cousineau D, Ten Hoeve J, Graeber TG, Schuelke M, Maltepe E, Kampmann M, Mendelsohn BA, Nakamura JL, Nakamura K. Defining the ATPome reveals cross-optimization of metabolic pathways. Nature communications 2020. PMID: 32859923


  27. Molbay M, Özaydin-Goksu E, Kipmen-Korgun D, Unal A, Ozekinci M, Cebeci E, Maltepe E, Korgun ET. Human placental trophoblast progenitor cells (hTPCs) promote angiogenesis and neurogenesis after focal cerebral ischemia in rats. The International journal of neuroscience 2020. PMID: 32772609


  28. Ornatowski W, Lu Q, Yegambaram M, Garcia AE, Zemskov EA, Maltepe E, Fineman JR, Wang T, Black SM. Complex interplay between autophagy and oxidative stress in the development of pulmonary disease. Redox biology 2020. PMID: 32818797


  29. Zhu T, Chiacchia S, Kameny RJ, Garcia De Herreros A, Gong W, Raff GW, Boehme JB, Maltepe E, Lasheras JC, Black SM, Datar SA, Fineman JR. Mechanical forces alter endothelin-1 signaling: comparative ovine models of congenital heart disease. Pulmonary circulation 2020. PMID: 32489641


  30. Antoni Garcia-Herreros, Rebecca J. Kameny, Terry Zhu, Jason Boehme, Gary Raff, Juan C. Lasheras, Stephen M. Black, Emin Maltepe, Sanjeev A. Datar, Jeffrey R. Fineman. Mechanical Forces Alter Endothelin-1 Signaling: Comparative Ovine Models of Congenital Heart Disease. Biophysical journal 2020. PMID:


  31. Fineman DC, Baer RJ, Chambers CD, Rajagopal S, Maltepe E, Rinaudo PF, Fineman JR, Jelliffe-Pawlowski LL, Steurer MA. Outcomes of pulmonary vascular disease in infants conceived with non-IVF fertility treatment and assisted reproductive technologies at 1 year of age. Pediatric pulmonology 2019. PMID: 31328432


  32. Johnson Kameny R, Datar SA, Boehme JB, Morris C, Zhu T, Goudy BD, Johnson EG, Galambos C, Raff GW, Sun X, Wang T, Chiacchia SR, Lu Q, Black SM, Maltepe E, Fineman JR. Ovine Models of Congenital Heart Disease and the Consequences of Hemodynamic Alterations for Pulmonary Artery Remodeling. American journal of respiratory cell and molecular biology 2019. PMID: 30620615


  33. Kelly GT, Faraj R, Zhang Y, Maltepe E, Fineman JR, Black SM, Wang T. Pulmonary Endothelial Mechanical Sensing and Signaling, a Story of Focal Adhesions and Integrins in Ventilator Induced Lung Injury. Frontiers in physiology 2019. PMID: 31105595


  34. Abed M, Verschueren E, Budayeva H, Liu P, Kirkpatrick DS, Reja R, Kummerfeld SK, Webster JD, Gierke S, Reichelt M, Anderson KR, Newman RJ, Roose-Girma M, Modrusan Z, Pektas H, Maltepe E, Newton K, Dixit VM. The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification. PloS one 2019. PMID: 30951545


  35. Zemskov EA, Lu Q, Ornatowski W, Klinger CN, Desai AA, Maltepe E, Yuan JX, Wang T, Fineman JR, Black SM. Biomechanical Forces and Oxidative Stress: Implications for Pulmonary Vascular Disease. Antioxidants & redox signaling 2019. PMID: 30623676


  36. Stefanski AL, Martinez N, Peterson LK, Callahan TJ, Treacy E, Luck M, Friend SF, Hermesch A, Maltepe E, Phang T, Dragone LL, Winn VD. Murine trophoblast-derived and pregnancy-associated exosome-enriched extracellular vesicle microRNAs: Implications for placenta driven effects on maternal physiology. PloS one 2019. PMID: 30730971


  37. Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, Krtolica A, Maltepe E. Correction: Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. PLoS biology 2019. PMID: 30677022


  38. Boehme J, Le Moan N, Kameny RJ, Loucks A, Johengen MJ, Lesneski AL, Gong W, Goudy BD, Davis T, Tanaka K, Davis A, He Y, Long-Boyle J, Ivaturi V, Gobburu JVS, Winger JA, Cary SP, Datar SA, Fineman JR, Krtolica A, Maltepe E. Preservation of myocardial contractility during acute hypoxia with OMX-CV, a novel oxygen delivery biotherapeutic. PLoS biology 2018. PMID: 30335746


  39. Morris CJ, Kameny RJ, Boehme J, Gong W, He Y, Zhu T, Maltepe E, Raff GW, Fineman JR, Datar SA. KLF2-mediated disruption of PPAR-? signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow. American journal of physiology. Heart and circulatory physiology 2018. PMID: 29631374


  40. Nguyen V, Sabeur K, Maltepe E, Ameri K, Bayraktar O, Rowitch DH. Sonic Hedgehog Agonist Protects Against Complex Neonatal Cerebellar Injury. Cerebellum (London, England) 2018. PMID: 29134361


  41. Emin Maltepe, Anna A. Penn. 5 Development, Function, and Pathology of the Placenta. 2018. PMID:


  42. Black SM, Field-Ridley A, Sharma S, Kumar S, Keller RL, Kameny R, Maltepe E, Datar SA, Fineman JR. Altered Carnitine Homeostasis in Children With Increased Pulmonary Blood Flow Due to Ventricular Septal Defects. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2017. PMID: 28723882


  43. Feuer S, Liu X, Donjacour A, Simbulan R, Maltepe E, Rinaudo P. Common and specific transcriptional signatures in mouse embryos and adult tissues induced by in vitro procedures. 2016. PMID: 27799627


  44. Boehme J, Sun X, Tormos KV, Gong W, Kellner M, Datar SA, Kameny RJ, Yuan JX, Raff GW, Fineman JR, Black SM, Maltepe E. Pulmonary artery smooth muscle cell hyperproliferation and metabolic shift triggered by pulmonary overcirculation. American journal of physiology. Heart and circulatory physiology 2016. PMID: 27591215


  45. Datar SA, Gong W, He Y, Johengen M, Kameny RJ, Raff GW, Maltepe E, Oishi PE, Fineman JR. Disrupted NOS signaling in lymphatic endothelial cells exposed to chronically increased pulmonary lymph flow. American journal of physiology. Heart and circulatory physiology 2016. PMID: 27199125


  46. Rafikova O, Meadows ML, Kinchen JM, Mohney RP, Maltepe E, Desai AA, Yuan JX, Garcia JG, Fineman JR, Rafikov R, Black SM. Metabolic Changes Precede the Development of Pulmonary Hypertension in the Monocrotaline Exposed Rat Lung. PloS one 2016. PMID: 26937637


  47. Simbulan RK, Liu X, Feuer SK, Maltepe E, Donjacour A, Rinaudo P. Adult male mice conceived by in vitro fertilization exhibit increased glucocorticoid receptor expression in fat tissue. 2015. PMID: 26511158


  48. Maltepe E, Fisher SJ. Placenta: the forgotten organ. 2015. PMID: 26443191


  49. Jason Boehme, Kathryn Tormos, Jeff Fineman, Emin Maltepe. Abstract 640: PASMC Hyperproliferation and Metabolic Shift in a Model of Pulmonary Overcirculation. 2015. PMID:


  50. Ameri K, Maltepe E. HIGD1A-mediated dormancy and tumor survival. 2015. PMID: 27308509


  51. Simbulan RK, Di Santo M, Liu X, Lin W, Donjacour A, Maltepe E, Shenoy A, Borini A, Rinaudo P. Embryonic stem cells derived from in vivo or in vitro-generated murine blastocysts display similar transcriptome and differentiation potential. 2015. PMID: 25723476


  52. Boehme J, Maltepe E. Spare hypoxia, spoil the child? The Journal of clinical investigation 2015. PMID: 25689257


  53. Ameri K, Jahangiri A, Rajah AM, Tormos KV, Nagarajan R, Pekmezci M, Nguyen V, Wheeler ML, Murphy MP, Sanders TA, Jeffrey SS, Yeghiazarians Y, Rinaudo PF, Costello JF, Aghi MK, Maltepe E. HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth. 2015. PMID: 25683712


  54. Zhou Y, Yuge A, Rajah AM, Unek G, Rinaudo PF, Maltepe E. LIMK1 regulates human trophoblast invasion/differentiation and is down-regulated in preeclampsia. 2014. PMID: 25307528


  55. Feuer SK, Donjacour A, Simbulan RK, Lin W, Liu X, Maltepe E, Rinaudo PF. Sexually dimorphic effect of in vitro fertilization (IVF) on adult mouse fat and liver metabolomes. 2014. PMID: 25211591


  56. Yuen TJ, Silbereis JC, Griveau A, Chang SM, Daneman R, Fancy SPJ, Zahed H, Maltepe E, Rowitch DH. Oligodendrocyte-encoded HIF function couples postnatal myelination and white matter angiogenesis. Cell 2014. PMID: 25018103


  57. Chelsea Bahney, Aaron Taylor, Ali Sadat, Kathryn Tormos, Ted Miclau, Emin Maltepe, Ralph Marcucio. Therapeutic delivery of placental stem cells to modulate vasculature and promote fracture repair (342.6). 2014. PMID:


  58. Feuer SK, Liu X, Donjacour A, Lin W, Simbulan RK, Giritharan G, Piane LD, Kolahi K, Ameri K, Maltepe E, Rinaudo PF. Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. 2014. PMID: 24684304


  59. Zeldovich VB, Clausen CH, Bradford E, Fletcher DA, Maltepe E, Robbins JR, Bakardjiev AI. Placental syncytium forms a biophysical barrier against pathogen invasion. 2013. PMID: 24348256


  60. Tache V, Ciric A, Moretto-Zita M, Li Y, Peng J, Maltepe E, Milstone DS, Parast MM. Hypoxia and trophoblast differentiation: a key role for PPARγ. 2013. PMID: 23767827


  61. Ameri K, Rajah AM, Nguyen V, Sanders TA, Jahangiri A, Delay M, Donne M, Choi HJ, Tormos KV, Yeghiazarians Y, Jeffrey SS, Rinaudo PF, Rowitch DH, Aghi M, Maltepe E. Nuclear localization of the mitochondrial factor HIGD1A during metabolic stress. PloS one 2013. PMID: 23646141


  62. Smith F, Hu D, Young NM, Lainoff AJ, Jamniczky HA, Maltepe E, Hallgrimsson B, Marcucio RS. The effect of hypoxia on facial shape variation and disease phenotypes in chicken embryos. 2013. PMID: 23592613


  63. Choi HJ, Sanders TA, Tormos KV, Ameri K, Tsai JD, Park AM, Gonzalez J, Rajah AM, Liu X, Quinonez DM, Rinaudo PF, Maltepe E. ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. 2013. PMID: 23437279


  64. G. Giritharan, M.W. Li, F. Di Sebastiano, F.J. Esteban, J.A. Horcajadas, K.C.K. Lloyd, A. Donjacour, E. Maltepe, P.F. Rinaudo. Effect of ICSI on gene expression and development of mouse preimplantation embryos. 2013. PMID:


  65. Kolahi KS, Donjacour A, Liu X, Lin W, Simbulan RK, Bloise E, Maltepe E, Rinaudo P. Effect of substrate stiffness on early mouse embryo development. 2012. PMID: 22860009


  66. Bloise E, Lin W, Liu X, Simbulan R, Kolahi KS, Petraglia F, Maltepe E, Donjacour A, Rinaudo P. Impaired placental nutrient transport in mice generated by in vitro fertilization. 2012. PMID: 22562173


  67. Giritharan G, Delle Piane L, Donjacour A, Esteban FJ, Horcajadas JA, Maltepe E, Rinaudo P. In vitro culture of mouse embryos reduces differential gene expression between inner cell mass and trophectoderm. 2012. PMID: 22383776


  68. Hunkapiller NM, Gasperowicz M, Kapidzic M, Plaks V, Maltepe E, Kitajewski J, Cross JC, Fisher SJ. A role for Notch signaling in trophoblast endovascular invasion and in the pathogenesis of pre-eclampsia. 2011. PMID: 21693515


  69. Giritharan G, Li MW, Di Sebastiano F, De Sebastiano F, Esteban FJ, Horcajadas JA, Lloyd KC, Donjacour A, Maltepe E, Rinaudo PF. Effect of ICSI on gene expression and development of mouse preimplantation embryos. 2010. PMID: 20889529


  70. Park AM, Sanders TA, Maltepe E. Hypoxia-inducible factor (HIF) and HIF-stabilizing agents in neonatal care. 2010. PMID: 20599462


  71. Delle Piane L, Lin W, Liu X, Donjacour A, Minasi P, Revelli A, Maltepe E, Rinaudo PF. Effect of the method of conception and embryo transfer procedure on mid-gestation placenta and fetal development in an IVF mouse model. 2010. PMID: 20576634


  72. Maltepe E, Bakardjiev AI, Fisher SJ. The placenta: transcriptional, epigenetic, and physiological integration during development. 2010. PMID: 20364099


  73. Maltepe E, Saugstad OD. Oxygen in health and disease: regulation of oxygen homeostasis--clinical implications. 2009. PMID: 18852690


  74. Olga Genbacev, Paolo F Rinaudo, Emin Maltepe. Role of oxygen in early development and embryonic stem cell derivation. Stem Cells in Human Reproduction 2006. PMID:


  75. K. Red-Horse, J. Rivera, A. Schanz, Y. Zhou, V. Winn, M. Kapidzic, E. Maltepe, K. Okazaki, R. Kochman, K. C. Vo, L. Giudice, A. Erlebacher, J. M. McCune, C. A. Stoddart, S. J. Fisher. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. 2006. PMID:


  76. Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. 2006. PMID: 16998586


  77. Red-Horse K, Rivera J, Schanz A, Zhou Y, Winn V, Kapidzic M, Maltepe E, Okazaki K, Kochman R, Vo KC, Giudice L, Erlebacher A, McCune JM, Stoddart CA, Fisher SJ. Literature watch. Cytotrophoblast induction of arterial apoptosis and lymphangiogenesis in an in vivo model of human placentation. 2006. PMID: 17394406


  78. Okazaki K, Maltepe E. Oxygen, epigenetics and stem cell fate. 2006. PMID: 17465821


  79. Cowden Dahl KD, Fryer BH, Mack FA, Compernolle V, Maltepe E, Adelman DM, Carmeliet P, Simon MC. Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation. 2005. PMID: 16287860


  80. Maltepe E, Krampitz GW, Okazaki KM, Red-Horse K, Mak W, Simon MC, Fisher SJ. Hypoxia-inducible factor-dependent histone deacetylase activity determines stem cell fate in the placenta. 2005. PMID: 15987772


  81. Adelman DM, Gertsenstein M, Nagy A, Simon MC, Maltepe E. Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. 2000. PMID: 11124810


  82. David M. Adelman, Marina Gertsenstein, Andras Nagy, M. Celeste Simon, Emin Maltepe. Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses. 2000. PMID:


  83. Shiels H, Li X, Schumacker PT, Maltepe E, Padrid PA, Sperling A, Thompson CB, Lindsten T. TRAF4 deficiency leads to tracheal malformation with resulting alterations in air flow to the lungs. 2000. PMID: 10934170


  84. Maltepe E, Keith B, Arsham AM, Brorson JR, Simon MC. The role of ARNT2 in tumor angiogenesis and the neural response to hypoxia. 2000. PMID: 10873592


  85. Adelman DM, Maltepe E, Simon MC. HIF-1 is essential for multilineage hematopoiesis in the embryo. 2000. PMID: 10849668


  86. Adelman DM, Maltepe E, Simon MC. Multilineage embryonic hematopoiesis requires hypoxic ARNT activity. 1999. PMID: 10521392


  87. Chandel NS, Maltepe E, Goldwasser E, Mathieu CE, Simon MC, Schumacker PT. Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. 1998. PMID: 9751731


  88. Maltepe E, Simon MC. Oxygen, genes, and development: an analysis of the role of hypoxic gene regulation during murine vascular development. 1998. PMID: 9625296


  89. Jain S, Maltepe E, Lu MM, Simon C, Bradfield CA. Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse. 1998. PMID: 9545558


  90. An WG, Kanekal M, Simon MC, Maltepe E, Blagosklonny MV, Neckers LM. Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha. 1998. PMID: 9537326


  91. Maltepe E, Schmidt JV, Baunoch D, Bradfield CA, Simon MC. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. 1997. PMID: 9121557


  92. Díaz MO, Pomykala HM, Bohlander SK, Maltepe E, Malik K, Brownstein B, Olopade OI. Structure of the human type-I interferon gene cluster determined from a YAC clone contig. 1994. PMID: 8001965


  93. Porterfield BW, Pomykala H, Maltepe E, Bohlander SK, Rowley JD, Diaz MO. The use of methylthioadenosine phosphorylase activity to select for human chromosome 9 in interspecies and intraspecies hybrid cells. 1993. PMID: 7507266


  94. Olopade OI, Bohlander SK, Pomykala H, Maltepe E, Van Melle E, Le Beau MM, Diaz MO. Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia. 1992. PMID: 1385305