Jessica Neely, MD

Dr. Neely is a pediatric rheumatologist who studies a rare pediatric condition known as juvenile dermatomyositis using multi-modal single cell technologies of biological samples collected from her patients. Her research seeks to identify novel treatment targets and biomarkers for this condition to develop precision medicine approaches to care. Her work also seeks to better understand the immune dysregulation that leads to juvenile dermatomyositis.
Education
06/2019 - Pediatric Rheumatology Fellowship, University of California, San Francisco
06/2016 - Pediatric Residency, University of California, San Francisco
MD, 05/2013 - Medicine, University of Kentucky College of Medicine
Websites

  1. Covert LT, Truskey GA, Kandil S, Neely J, Turnier JL, Ardalan K, Dvergsten JA. Unmasking inflammation in juvenile dermatomyositis: myokine profiles of patients and bioengineered human muscle. Frontiers in immunology 2025. PMID: 41488665


  2. Swaminathan S, Naik N, Shenoi S, Vandenbergen S, Turnier JL, Zheng Z, Neely J, Andrews JS, Lood C. Neutrophil lymphocyte ratio as a marker of skin disease activity in older children with juvenile dermatomyositis. Pediatric rheumatology online journal 2025. PMID: 41286892


  3. Neely J, Sabbagh SE, Dvergsten J, Madubata C, Berthier CC, Zheng Z, Goudsmit C, Matossian S, Ferris SP, Fragiadakis GK, Sirota M, Kahlenberg JM, Kim H, Turnier JL, CARRA Registry Investigators and CARRA Translational Medicine for Juvenile Myositis Working Group. Discovery of tissue-specific proteomic signatures in juvenile dermatomyositis highlights pathways reflecting persistent disease activity, clinical heterogeneity, and myositis-specific autoantibody subtype. Annals of the rheumatic diseases 2025. PMID: 40915939


  4. Rabadam G, Wibrand C, Flynn E, Hartoularos GC, Sun Y, Madubata C, Fragiadakis GK, Ye CJ, Kim S, Gartner ZJ, Sirota M, Neely J. Coordinated immune dysregulation in juvenile dermatomyositis revealed by single-cell genomics. JCI insight 2024. PMID: 38743491


  5. Yang MM, Lee S, Neely J, Hinchcliff M, Wolters PJ, Sirota M. Gene expression meta-analysis reveals aging and cellular senescence signatures in scleroderma-associated interstitial lung disease. Frontiers in immunology 2024. PMID: 38348044


  6. Huang Y, Sompii-Montgomery L, Patti J, Pickering A, Yasin S, Do T, Baker E, Gao D, Abdul-Aziz R, Behrens EM, Canna S, Clark M, Co DO, Collins KP, Eberhard B, Friedman M, Graham TB, Hahn T, Hersh AO, Hobday P, Holland MJ, Huggins J, Lu PY, Mannion ML, Manos CK, Neely J, Onel K, Orandi AB, Ramirez A, Reinhardt A, Riskalla M, Santiago L, Stoll ML, Ting T, Grom AA, Towe C, Schulert GS. Disease Course, Treatments, and Outcomes of Children With Systemic Juvenile Idiopathic Arthritis-Associated Lung Disease. Arthritis care & research 2023. PMID: 37691306


  7. Neely J, Ardalan K, Huber A, Kim S, Childhood Arthritis and Rheumatology Research Alliance Investigators. Baseline characteristics of children with juvenile dermatomyositis enrolled in the first year of the new Childhood Arthritis and Rheumatology Research Alliance registry. Pediatric rheumatology online journal 2022. PMID: 35854378


  8. Neely J, Hartoularos G, Bunis D, Sun Y, Lee D, Kim S, Ye CJ, Sirota M. Multi-Modal Single-Cell Sequencing Identifies Cellular Immunophenotypes Associated With Juvenile Dermatomyositis Disease Activity. Frontiers in immunology 2022. PMID: 35799782


  9. Rychkov D, Neely J, Oskotsky T, Yu S, Perlmutter N, Nititham J, Carvidi A, Krueger M, Gross A, Criswell LA, Ashouri JF, Sirota M. Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis. 2021. PMID: 34177888


  10. Neely J, Shalen J, Sturrock H, Kim S, Childhood Arthritis and Rheumatology Research Alliance Investigators. Access to Care and Diagnostic Delays in Juvenile Dermatomyositis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. ACR Open Rheumatology 2021. PMID: 33932146


  11. Neely J, Kim S. Advances Toward Precision Medicine in Juvenile Dermatomyositis. Current rheumatology reports 2019. PMID: 31813083


  12. Neely J, Rychkov D, Paranjpe M, Waterfield M, Kim S, Sirota M. Gene Expression Meta-Analysis Reveals Concordance in Gene Activation, Pathway, and Cell-Type Enrichment in Dermatomyositis Target Tissues. ACR Open Rheumatology 2019. PMID: 31872188


  13. Neely J, Long CS, Sturrock H, Kim S, Childhood Arthritis and Rheumatology Research Alliance Registry Investigators. Association of Short-Term Ultraviolet Radiation Exposure and Disease Severity in Juvenile Dermatomyositis: Results From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry. Arthritis care & research 2019. PMID: 30714338


  14. Neely JA, Dvorak CC, Pantell MS, Melton A, Huang JN, Shimano KA. Autoimmune Cytopenias in Pediatric Hematopoietic Cell Transplant Patients. Frontiers in pediatrics 2019. PMID: 31131266


  15. Neely J, von Scheven E. Autoimmune haemolytic anaemia and autoimmune thrombocytopenia in childhood-onset systemic lupus erythematosus: updates on pathogenesis and treatment. Current opinion in rheumatology 2018. PMID: 29979258


  16. Sharma A, Easow Mathew M, Sriganesh V, Neely JA, Kalipatnapu S. Gene therapy for haemophilia. 2014. PMID: 25394678