Philip Rosenthal, MD
Dr. Rosenthal is a prolific author and a recipient of a number of professional honors and awards and is committed to clinical service, research and education. He has published numerous research articles on hepatitis. Currently, Dr. Rosenthal is pursuing research on the pharmaceutical treatment of hepatitis B and C, genetics and immunology of biliary disease, use of bioartificial liver support utilizing porcine hepatocytes for patients with fulminant liver failure, as well as researching the quality of life following liver transplantation in children.
Dr. Rosenthal’s professional services to the public include television, newspaper and radio interviews on various topics such as hepatitis A, B, and C, and liver transplants for local, national and international audiences. He is consultant to organizations such as the American Liver Foundation, Parents of Kids with Infectious Disease, the Centers for Disease Control and Prevention (CDC), and the National Institute of Health (NIH)
Education
Honors and Awards
Websites
Kizza J, Katairo T, Kakuru A, Nsengimaana B, Esilu T, Wiringilimaana I, Semakuba FD, Gerlovina I, Hathaway N, Briggs J, Tukwasibwe S, Kiwuwa SM, Kamya MR, Nankabirwa JI, Dorsey G, Rosenthal PJ. Recurrent Plasmodium falciparum Parasitemia and Drug Resistance Mutations During Intermittent Preventive Treatment of Malaria in Pregnancy in Uganda. The Journal of infectious diseases 2026. PMID: 41679334
Nachega JB, Mbala-Kingebeni P, Mulangu S, Ndembi N, Preiser W, Skinner D, Sam-Agudu NA, Ntoumi F, Tegally H, Baxter C, Oliveira T, Bosa HK, Kaleebu P, Kallay O, Uthman OA, Mills EJ, Rosenthal PJ, Zumla A, Muyembe-Tamfum JJ. Ebola outbreak caused by Bundibugyo virus: challenges and priorities for epidemic preparedness and response. Lancet (London, England) 2026. PMID: 42263728
Maitland K, Okao M, Conrad MD, Etwop T, Akite M, Oguda E, Alaroker F, Aromut D, Muhindo R, Uyoga S, Olupot-Olupot P, Mogaka C, Connon R, Katairo T, Okitwi M, Briggs J, Gibb DM, Day NPJ, White NJ, Williams TN, Dondorp AM, Walker AS, George EC, Rosenthal PJ, SMAART-CHARISMA group. Intravenous Artesunate in Artemisinin-Resistant Severe Malaria in Uganda. The New England journal of medicine 2026. PMID: 42234998
Plucinski MM, Wesolowski A, Gerlovina I, Taylor AR, Briggs J, Aranda-Díaz A, Golumbeanu M, Bajic M, Bailey JA, Barratt JLN, Buckee C, Deme AB, Felger I, Ghansah A, Hastings I, Kattenberg JH, Mayor A, Menard D, Moriarty LF, Neafsey D, Okell L, Oyier I, Raman J, Rosenthal PJ, Rosanas-Urgell A, Verity R, Volkman SK, Nsanzabana C, Greenhouse B. Target product profiles of laboratory and data analytical frameworks for genotyping to monitor antimalarial efficacy. PLOS global public health 2026. PMID: 42213656
da Costa Clementino L, Bartlett PJ, Fernandes GFS, Honorio RI, Legac J, Dos Santos JL, Rosenthal PJ, Garcia CRS, Thomas AP, Graminha MAS. Furoxan derivatives with antimalarial activity that disrupt P. falciparum endoplasmic reticulum calcium homeostasis. International journal for parasitology. Drugs and drug resistance 2026. PMID: 42142428
Bower-Lepts C, Jangra A, Kanatani S, Tripathi A, Mlambo G, McCotter-González A, Romano L, Orena S, Okitwi M, Niaré K, Rosenthal PJ, Conrad M, Sinnis P, Mok S. A Plasmodium falciparum PX1 haplotype is associated with reduced susceptibility to artemisinin and lumefantrine. bioRxiv : the preprint server for biology 2026. PMID: 42182324
He MS, He S, Roh M, Kakuru A, Jagannathan P, Dorsey G, Rosenthal P, Aweeka F, Huang L. Development and validation of UHPLC-MS/MS methods for determination of piperaquine in quantitative dried blood samples and microvolume plasma samples. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2026. PMID: 42090845
Nankabirwa JI, Kakuru A, Nguyen AT, Roh ME, Aguti M, Adrama H, Kizza J, Olwoch P, Camanag K, Benjamin-Chung J, Rosenthal PJ, Kamya MR, Dorsey G, Jagannathan P. Impact of intermittent preventive treatment for malaria in pregnancy with sulfadoxine-pyrimethamine, dihydroartemisinin-piperaquine, and their combination on infant outcomes: A randomized controlled trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2026. PMID: 42007686
Kancharla P, Dodean RA, Li Y, Zhang X, Kelly S, Charlton J, Binauhan AJ, Navarrete K, Garcia L, Mu J, Lu J, Caridha D, Madejczyk MS, Jin X, Dennis WE, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca J, Vuong C, Pannone K, Dinh HT, Mdaki K, Leed S, Martin ML, Pybus BS, Chin GC, Chim-Ong A, Cui L, Qahash T, Shoue DA, Ferdig MT, Mockenhaupt FP, van Loon W, Ndoli JM, Kudyba H, Vega-Rodriguez J, Okitwi M, Kreutzfeld O, Docan C, Green C, Liu Y, Agulay A, Mirsalis J, Farrell SN, Probst AS, Nilsen A, Alday PH, Stone Doggett J, McFadden GI, Goodman CD, Catteruccia F, Rosenthal PJ, Riscoe MK, Cooper RA, Roth A, Kelly JX. Potent acridone antimalarial against all three life stages of Plasmodium. Nature communications 2026. PMID: 41980931
Aguti M, Nankabirwa JI, Kizza J, Kakuru A, Ssemukuye T, Adrama H, Olwoch P, Opira B, Odongo B, Camanag K, Nakalembe M, Clark T, Rosenthal PJ, Dorsey G, Jaganathan P, Kamya MR. Natural History and the Burden of Malaria During the First Year of Life in the High-Transmission Setting of Uganda. The American journal of tropical medicine and hygiene 2026. PMID: 41926926
Diamond T, Chapin CA, Diorio CJ, McCuaig S, Lau M, Chu N, Gibson NM, Kreiger PA, Horslen S, Loomes KM, Banc-Husu AM, Chu J, Jensen MK, Leung DH, Narang A, Carter BA, Elisofon S, Fischer R, Lobritto SJ, Leonis M, Peters AL, Rodriguez-Baez N, Romero R, Rosenthal P, Rudnick D, Squires J, Sundaram S, Tolliver KM, Valentino P, Durkalski V, Alonso EM, Behrens EM. CD8 TRM-like T cells expressing perforin and IFN-γ define a pediatric activated T-cell acute liver failure endotype. Hepatology communications 2026. PMID: 41921202
Katairo T, Asua V, Semakuba FD, Nsengimaana B, Kiyaga S, Hathaway N, Murie K, Tukwasibwe S, Wiringilimaana I, Nakasaanya J, Mwubaha C, Achom KB, Esilu TE, Ayitewala A, Mbabazi M, Kabbale KD, Mulondo J, Watyekele E, Aranda-Diaz A, Maiteki CS, Opigo J, Dorsey G, Nsobya SL, Kamya MR, Agaba BB, Ssewanyana I, Greenhouse B, Rosenthal PJ, Briggs J, Conrad MD. Sustained High Prevalence of Multiple Antimalarial Drug Resistance Markers in Uganda in 2023-24. medRxiv : the preprint server for health sciences 2026. PMID: 41891011
Kastenberg ZJ, Beil CA, Henn L, Alonso EM, Hsu EK, Wang K, Ng VL, Gupta NA, Magee JC, Merion RM, Horslen S, Karpen SJ, Kohli R, Loomes K, Miethke A, Tolliver KM, Rosenthal P, Harpavat S, Sokol RJ, Guthery SL, and the Childhood Liver Disease Research Network (ChiLDReN). Demographic Factors and Biliary Atresia: A Childhood Liver Disease Research Network Study. Pediatrics 2026. PMID: 41707679
Kiyaga S, Mbabazi M, Katairo T, Kabbale KD, Asua V, Nsengimaana B, Wiringilimaana I, Semakuba FD, Mwubaha C, Nakasaanya J, Watyekele E, Ayitewala A, Tukwasibwe S, Mulondo J, Nsobya SL, Agaba B, Maiteki-Sebuguzi C, Kamya MR, Kateete DP, Nabende JN, Jjingo D, Mboowa G, Batte C, Ssewanyana I, Aranda-Díaz A, Dorsey G, Rosenthal PJ, Conrad M, Greenhouse B, Briggs J. Accuracy of Plasmodium falciparum genetic data for estimating parasite prevalence and malaria incidence in Uganda. Malaria journal 2026. PMID: 41723456
Wadhwani SI, Spector PR, Feldman AG, Furuya KN, Hartjes K, Jarasvaraparn C, Kelly B, Lerret SM, Mysore K, Pawaria A, Rosenthal P, Shui A, Slowik V, Taylor S, Vittorio J, Valentino PL, Society of Pediatric Liver Transplantation (SPLIT). Defining the Society of Pediatric Liver Transplantation (SPLIT) research agenda: A Delphi consensus project. Hepatology communications 2026. PMID: 41730231
Mbabazi M, Kiyaga S, Katairo T, Kabbale KD, Asua V, Kagurusi BA, Wiringilimaana I, Nsengimaana B, Semakuba FD, Nakasaanya J, Ayitewala A, Watyekele E, Nabende I, Kayondo TM, Arinaitwe E, Mulondo J, Tukwasibwe S, Nsobya SL, Agaba B, Maiteki C, Jjingo D, Kateete DP, Kamya MR, Ssewanyana I, Aranda-Diaz A, Conrad MD, Murphy M, Gerlovina I, Epstein A, Rodriguez-Barraquer I, Rosenthal PJ, Dorsey G, Greenhouse B, Briggs J. Imported malaria predominates in near-elimination settings in Southwestern Uganda. medRxiv : the preprint server for health sciences 2026. PMID: 41646777
Adrama H, Dela Cruz EJ, Ozarslan N, Kakuru A, Odongo B, Gaw SL, Benjamin-Chung J, Kizza J, Aguti M, Ategeka J, Olwoch P, Nakalembe M, Opira B, Clark TD, Kamya MR, Rosenthal PJ, Dorsey G, Roh ME. Impact of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine on sexually transmitted and reproductive tract infections: results from a randomized trial in Uganda. International journal of epidemiology 2026. PMID: 41657027
Aguti M, Kizza J, Kakuru A, Nakalembe M, Nankabirwa JI, Gaw SL, Opira B, Ssemukuye T, Ozarslan N, Ranjit A, Dela Cruz E, Clark TD, Roh ME, Jagannathan P, Rosenthal PJ, Adrama H, Olwoch P, Mayende J, Odongo B, John A, Kamya M, Dorsey G. Maternal and household risk factors for malaria in pregnancy and low birthweight: a prospective cohort study from Uganda. Malaria journal 2025. PMID: 41469677
McClure M, Oruni A, Arinaitwe E, Musiime A, Kyagamba P, Otto G, Adiga J, Rwatooro JA, Kilama M, Krezanoski P, Briggs J, Rosenthal PJ, Nankabirwa JI, Kamya MR, Dorsey G, Greenhouse B, Rodriguez-Barraquer I. Disentangling the roles of different vector species during a malaria resurgence in Eastern Uganda. PLOS global public health 2025. PMID: 41379838
Kiyaga S, Mbabazi M, Katairo T, Kabbale KD, Asua V, Nsengimaana B, Wiringilimaana I, Semakuba FD, Mwubaha C, Nakasaanya J, Watyekele E, Ayitewala A, Tukwasibwe S, Mulondo J, Nsobya SL, Agaba B, Maiteki-Sebuguzi C, Kamya MR, Kateete DP, Nabende JN, Jjingo D, Mboowa G, Batte C, Ssewanyana I, Aranda-Díaz A, Dorsey G, Rosenthal PJ, Conrad M, Greenhouse B, Briggs J. Accuracy of Plasmodium falciparum genetic data for estimating parasite prevalence and malaria incidence in Uganda. Research square 2025. PMID: 41510267
Bass LM, Hawthorne K, Magee JC, Shneider BL, Childhood Liver Disease Research Network (ChiLDReN). Secondary prophylaxis of variceal hemorrhage in biliary atresia-Analysis of prospective multicenter studies. Journal of pediatric gastroenterology and nutrition 2025. PMID: 41267542
Kumar A, Li Y, Zhang X, Gaddam M, Caridha D, Madejczyk MS, Jin X, Dennis WE, Chetree R, Blount C, DeLuca J, Vuong C, Kudyba K, Roncal N, Ashraf K, Lee PJ, Pannone K, Leed S, Dinh HT, Mdaki K, Navarrete K, Charlton J, Binauhan AJ, Qahash T, Kibe KM, Shoue DA, Checkley L, Ferdig MT, Chim-Ong A, Cui L, Orena S, Byaruhanga O, Assimwe J, Tibagambirwa I, Chithanna S, Dodean RA, Legac J, Kreutzfeld O, Rosenthal PJ, Cooper RA, Reynolds KA, Roth A, Kelly JX, Kancharla P. Optimization of Prodiginines as Single-Dose Curative Antimalarials. Journal of medicinal chemistry 2025. PMID: 41253140
Rosenthal PJ. Is Seasonal Malaria Chemoprevention with Sulfadoxine-Pyrimethamine/Amodiaquine Appropriate in East Africa? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2025. PMID: 41231735
Kizza J, Katairo T, Kakuru A, Nsengimaana B, Esilu T, Wiringilimaana I, Semakuba FD, Gerlovina I, Hathaway N, Briggs J, Tukwasibwe S, Kiwuwa SM, Kamya MR, Nankabirwa JI, Dorsey G, Rosenthal PJ. Recurrent Plasmodium falciparum parasitemia and drug resistance mutations during intermittent preventive treatment of malaria in pregnancy in Uganda. medRxiv : the preprint server for health sciences 2025. PMID: 41282777
Haney RS, Butler JH, Wardlaw LA, Merino EF, Mendiola V, Cooper CA, Mathew J, Tumwebaze PK, Rosenthal PJ, Cooper RA, Kyle DE, Rizopoulos Z, Baud D, Brand S, Totrov M, Carlier PR, Cassera MB. Characterization of β-Carboline Derivatives Reveals a High Barrier to Resistance and Potent Activity against Ring-Stage and DHA-Induced Dormant Plasmodium falciparum. ACS infectious diseases 2025. PMID: 41105262
Rosenthal PJ. Improving antimalarial therapeutic efficacy studies. The Lancet. Infectious diseases 2025. PMID: 41043440
Shneider BL, Kanchi RS, Grimm SL, Devaraj S, Emamaullee J, Schraw J, Lupo PJ, Bezerra JA, Loomes KM, Magee JC, Sokol RJ, Wang KS, Kriegmeier A, Hsu E, Molleston JP, Rosenthal P, Kohli R, Karpen SJ, Horslen SP, Jensen MK, Barbetta A, Coarfa C, Childhood Liver Disease Research Network. Plasma proteome correlations with liver stiffness in pediatric cholestasis implicate epithelial to mesenchymal transition. Hepatology communications 2025. PMID: 41021277
Kakuru A, Kizza J, Aguti M, Adrama H, Ategeka J, Olwoch P, Nakalembe M, Nankabirwa JI, Opira B, Ozarslan N, Ranjit A, Dela Cruz E, Clark TD, Roh ME, Gaw SL, Jagannathan P, Rosenthal PJ, Kamya MR, Dorsey G. Dihydroartemisinin-piperaquine plus sulfadoxine-pyrimethamine versus either drug alone for intermittent preventive treatment of malaria in pregnancy: A double-blind, randomized, controlled phase 3 trial from Uganda. PLoS medicine 2025. PMID: 40966190
Aguti M, Kizza J, Kakuru A, Nakalembe M, Nankabirwa JI, Gaw SL, Opira B, Ssemukuye T, Ozarslan N, Ranjit A, Cruz E, Clark TD, Roh ME, Jagannathan P, Rosenthal PJ, Adrama H, Olwoch P, Mayende J, Odongo B, John A, Kamya MR, Dorsey G. Maternal and household risk factors for malaria in pregnancy and low birthweight: a prospective cohort study from Uganda. Research square 2025. PMID: 41001541
Shneider BL, Goodrich NP, Ye W, Molleston JP, Leung DH, Sokol RJ, Cavallo L, Wang K, Valentino PL, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Miethke AG, Loomes KM, Kohli R, Karpen SJ, Kamath BM, Jensen MK, Bezerra JA, Bass LM, Magee JC, ChiLDReN. Prospective Multicenter Longitudinal Measurement of Liver Stiffness in School-Age Children With Cholestatic Liver Disease. Gastro hep advances 2025. PMID: 41142527
Lebel PM, Jeyakumar I, Khoo MWL, Emorut J, Charlton C, Saxena A, Jacobsen A, Huynh E, Wu W, Courville G, Fu PC, Raghavan M, Puccinelli R, Olwoch P, Dorsey G, Rosenthal PJ, DeRisi J, Gomez-Sjoberg R. Remoscope: a label-free imaging cytometer for malaria diagnostics. Transactions of the Royal Society of Tropical Medicine and Hygiene 2025. PMID: 40631413
Kamya MR, Nankabirwa JI, Ebong C, Asua V, Kiggundu M, Orena S, Okitwi M, Tukwasibwe S, Agaba B, Kyabayinze D, Opigo J, Rutazana D, Binagwa B, Mugwanya E, Babirye S, Sebikaari G, Condo PM, Appiah G, Nsobya SL, Conrad MD, Rosenthal PJ, Moriarty LF, Yeka A. Efficacies of artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine, and artesunate-pyronaridine for the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6 months to 10 years in Uganda: a randomised, open The Lancet. Infectious diseases 2025. PMID: 40845863
Maxwell SL, Price JC, Perito ER, Rosenthal P, Wojcicki JM. Weight gain in infancy and metabolic dysfunction-associated steatotic liver disease (MASLD) in a prospective birth cohort of Latino children. Maternal health, neonatology and perinatology 2025. PMID: 40814062
McClure M, Arinaitwe E, Kamya MR, Rosenthal PJ, Nankabirwa J, Kilama M, Musiime A, Dorsey G, Greenhouse B, Rodriguez-Barraquer I. Relating household entomological measures to individual malaria risk. Malaria journal 2025. PMID: 40804728
Okitwi M, Orena S, Tumwebaze PK, Katairo T, Taremwa Y, Byaruhanga O, Tukwasibwe S, Nsobya SL, Legac J, Bailey JA, Cooper RA, Conrad MD, Rosenthal PJ. Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019-2024. Nature communications 2025. PMID: 40783405
Klope MT, Talukder P, Blank BR, Chelebieva S, Chen J, Fontaine SD, Gonciarz RL, Jaishankar P, Lee GJ, Legac J, Mathur V, Narayan A, Okitwi M, Orena S, Settineri NS, Tapia JA, Taremwa Y, Tumwebaze PK, Vinod A, Burrows JN, Rosenthal PJ, Cooper RA, Renslo AR. Identifying a next-generation antimalarial trioxolane in a landscape of artemisinin partial resistance. Science advances 2025. PMID: 40779626
Li J, Wang X, Lackner AI, Narasimhan P, Li L, Mallajosyula V, Johnson MM, Höbler AL, Kirosingh AS, Braun AE, Nankya F, Musinguzi K, Kakuru A, Kamya M, Rosenthal PJ, Dorsey G, Jagannathan P, Angelo M, Pollheimer J, Gaw SL, Winn VD, Nadeau KC, Davis MM. Regulatory KIR+CD8+ T cells are elevated during human pregnancy. Science translational medicine 2025. PMID: 40768597
Arzika AM, Abdou A, Maliki R, Lebas E, Cook C, Vanderschelden B, O'Brien KS, Cotter SY, Varnado NE, Callahan EK, Bailey RL, West SK, Rosenthal PJ, Porco TC, Lietman TM, Keenan JD, MORDOR-Niger Study Group. Biannual Mass Azithromycin Distributions for Preschool Children and Malaria Parasitemia: A Secondary Analysis of the MORDOR Cluster Randomized Trial. JAMA network open 2025. PMID: 40824641
Nardella F, Jiang T, Wang L, Bohmer MJ, Chakraborty S, Okombo J, Calla J, Silva TM, Pazicky S, Che J, Jeon J, Vincent E, Boonyalai N, Coyle R, Buchanan MJ, Schaefer S, Chen D, Khan A, Mayville E, De Souza ML, Treat M, Charlton J, Tumwebaze PK, Tjia S, Montejo L, Cover K, Rosenthal PJ, Cooper RA, Bozdech Z, Lee MCS, Chakrabarti R, Desai SA, Fidock DA, Wang J, Gray NS, Winzeler EA, Chakrabarti D. Plasmodiumfalciparum protein kinase 6 and hemozoin formation are inhibited by a type II human kinase inhibitor exhibiting antimalarial activity. Cell chemical biology 2025. PMID: 40628257
Adrama H, Dela Cruz EJ, Ozarslan N, Kakuru A, Odongo B, Gaw SL, Benjamin-Chung J, Kizza J, Aguti M, Ategeka J, Olwoch P, Nakalembe M, Opira B, Clark TD, Kamya MR, Rosenthal PJ, Dorsey G, Roh ME. Impact of intermittent preventive treatment of malaria in pregnancy with sulfadoxine-pyrimethamine on sexually transmitted and reproductive tract infections: results from a randomised trial in Uganda. medRxiv : the preprint server for health sciences 2025. PMID: 40630588
Kancharla P, Dodean RA, Li Y, Zhang X, Kelly S, Charlton J, Binauhan A, Garcia L, Caridha D, Madejczyk MS, Jin X, Dennis WE, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca J, Vuong C, Pannone K, Dinh HT, Mdaki K, Leed S, Martin ML, Pybus BS, Chimong A, Cui L, Vega-Rodriguez J, Okitwi M, Kreutzfeld O, Docan C, Green C, Liu Y, Agulay A, Mirsalis J, Farrell SN, McFadden GI, Goodman CD, Probst AS, Nilsen A, Catteruccia F, Rosenthal PJ, Riscoe M, Cooper R, Roth A, Kelly J. Potent Acridone Antimalarial against All Three Life Stages of Plasmodium. Research square 2025. PMID: 40678217
Niaré K, Crudale R, Fola AA, Wernsman Young N, Asua V, Conrad MD, Gashema P, Ghansah A, Hangi S, Ishengoma DS, Mazarati JB, Zeleke AJ, Rosenthal PJ, Djimdé AA, Juliano JJ, Bailey JA. Highly multiplexed molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole-genome sequencing assessments for selection and relatedness. Frontiers in genetics 2025. PMID: 40574802
Katairo T, Asua V, Nsengimaana B, Tukwasibwe S, Semakuba FD, Wiringilimaana I, Kagurusi BA, Mwubaha C, Nakasaanya J, Garg S, Kiyaga S, Mbabazi M, Kabbale KD, Ayitewala A, Nsobya SL, Kamya MR, Ssewanyana I, Bailey JA, Aranda-Díaz A, Rosenthal PJ, Greenhouse B, Briggs J, Conrad MD. Performance of molecular inversion probe DR23K and Paragon MAD4HatTeR Amplicon sequencing panels for detection of Plasmodium falciparum mutations associated with antimalarial drug resistance. Malaria journal 2025. PMID: 40506703
Kumar A, Li Y, Zhang X, Jin X, Dennis WE, Chetree R, Blount C, Caridha D, Madejczyk MS, Lee PJ, Pannone K, DeLuca J, Vuong C, Leed S, Dinh HT, Mdaki K, Mahato R, Sen P, Mondal T, Phukan K, Saha A, Chim-Ong A, Cui L, Valmon R, Chithanna S, Dodean RA, Peyton DH, Orena S, Assimwe J, Tibagambirwa I, Angutoko P, Legac J, Kreutzfeld O, Rosenthal PJ, Chenu E, Duffy J, Roth A, Reynolds KA, Kelly JX, Kancharla P. Optimization of Tambjamines Active against Multiple Stages of Malaria Parasites. Journal of medicinal chemistry 2025. PMID: 40450579
Nguyen TD, Zupko RJ, Conrad MD, Rukundo GB, Farinha CC, Asua VD, Tran KT, Grace DM, Rosenthal PJ, Agaba BB, Kamya MR, Opigo J, Boni MF. Slowing the spread of treatment failure to artemisinin-based combination therapies in Uganda. medRxiv : the preprint server for health sciences 2025. PMID: 40463542
Dodean RA, Li Y, Zhang X, Caridha D, Madejczyk MS, Jin X, Dennis WE, Chetree R, Kudyba K, McEnearney S, Lee PJ, Blount C, DeLuca J, Vuong C, Pannone K, Dinh HT, Mdaki K, Leed S, Martin ML, Pybus BS, Pou S, Winter RW, Liebman KM, Williams R, Kumar A, Chim-Ong A, Cui L, Orena S, Assimwe J, Tibagambirwa I, Byaruhanga O, Angutoko P, Legac J, Kreutzfeld O, Rosenthal PJ, Cooper RA, Nilsen A, Riscoe MK, Roth A, Kancharla P, Kelly JX. Development of Next-Generation Antimalarial Acridones with Radical Cure Potential. Journal of medicinal chemistry 2025. PMID: 40179277
Gonzalez-Peralta RP, Wen JW, Hardikar W, Karnsakul WW, Whitworth S, Lin CH, Indolfi G, Rosenthal P, Balistreri W, Schwarz KB, Honegger JR, Zhang X, Svarovskaia EC, Suri V, Kersey K, Leung DH. Long-term efficacy and safety of sofosbuvir-based direct-acting antiviral regimens in paediatric patients with hepatitis C virus infection: an international registry study. The Lancet. Child & adolescent health 2025. PMID: 40113366
Meier-Scherling CPG, Watson OJ, Asua V, Ghinai I, Katairo T, Garg S, Conrad MD, Rosenthal PJ, Okell LC, Bailey JA. Selection of Plasmodium falciparum kelch13 mutations in Uganda in comparison with southeast Asia: a modelling study. The Lancet. Microbe 2025. PMID: 40112841
Niaré K, Crudale R, Fola AA, Wernsman Young N, Asua V, Conrad M, Gashema P, Ghansah A, Hangi S, Ishengoma DS, Mazarati JB, Zeleke AJ, Rosenthal PJ, Djimdé AA, Juliano JJ, Bailey JA. Highly multiplex molecular inversion probe panel in Plasmodium falciparum targeting common SNPs approximates whole genome sequencing assessments for selection and relatedness. medRxiv : the preprint server for health sciences 2025. PMID: 40162260
Rosenthal PJ, Hamer DH, Bausch DG, Nishi JB, Fidock DA. US Public Health and Biomedical Research Institutions Help Keep the World Safe and Deserve Continued Strong Support. The American journal of tropical medicine and hygiene 2025. PMID: 40080909
Ozarslan N, Mong C, Ategeka J, Li L, Buarpung S, Robinson JF, Kizza J, Kakuru A, Kamya MR, Dorsey G, Rosenthal PJ, Gaw SL. Placental malaria induces a unique methylation profile associated with fetal growth restriction. Epigenetics 2025. PMID: 40051167
McClure M, Arinaitwe E, Kamya MR, Rosenthal PJ, Nankabirwa J, Maxwell K, Musiime A, Dorsey G, Greenhouse B, Rodriguez-Barraquer I. Relating household entomological measures to individual malaria risk. Research square 2025. PMID: 39975909
Taylor SA, Harpavat S, Gromer KD, Andreev V, Loomes KM, Bezerra JA, Jarasvaraparn C, Wang K, Horslen S, Rosenthal P, Teckman J, Valentino PL, Ng VL, Karpen SJ, Sokol RJ, Alonso EM, Mack CL, Childhood Liver Disease Research Network (ChiLDReN). Increased serum GM-CSF at diagnosis of biliary atresia is associated with improved biliary drainage. Pediatric research 2025. PMID: 39881181
Katairo T, Asua V, Nsengimaana B, Tukwasibwe S, Semakuba FD, Wiringilimaana I, Garg S, Kiyaga S, Mbabazi M, Kabbale KD, Ayitewala A, Nsobya SL, Kamya MR, Ssewanyana I, Bailey JA, Aranda-Díaz A, Rosenthal PJ, Greenhouse B, Briggs J, Conrad MD. Performance of Molecular Inversion Probe DR23K and Paragon MAD4HatTeR Amplicon Sequencing Panels for Detection of Plasmodium falciparum Mutations Associated with Antimalarial Drug Resistance. Research square 2025. PMID: 39975885
Rosenthal PJ. Artemisinin Partial Resistance and the Treatment of Severe Malaria. JAMA 2025. PMID: 39540803
Okitwi M, Orena S, Tumwebaze PK, Katairo T, Taremwa Y, Byaruhanga O, Tukwasibwe S, Nsobya SL, Legac J, Cooper RA, Conrad MD, Rosenthal PJ. Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019-2024. medRxiv : the preprint server for health sciences 2025. PMID: 39802777
Martinez-Vega R, Ishengoma DS, Gosling R, Rosenthal PJ, Dondorp A, Barnes KI, Nsanzabana C, Djimde AA, Ochola-Oyier LI, Tibenderana J, Chimumbwa J, Golassa L, Kapologwe NA, Mbacham WF, Kamya MR, Fidock DA, Komatsu R, von Seidlein L, Dhorda M. Regional action needed to halt antimalarial drug resistance in Africa. Lancet (London, England) 2024. PMID: 39674185
Gomez-Gonzalez PJ, Gupta A, Drought LG, Patel A, Okombo J, van der Watt M, Walker-Gray R, Schindler KA, Burkhard AY, Yeo T, Narwal SK, Bloxham TS, Flueck C, Walker EM, Rey JA, Fairhurst KJ, Reader J, Park H, Pollard HG, Stewart LB, Brandner-Garrod L, Kristan M, Sterk GJ, van Nuland YM, Manko E, van Schalkwyk DA, Zheng Y, Leurs R, Dechering KJ, Aguiar ACC, Guido RVC, Pereira DB, Tumwebaze PK, Nosbya SL, Rosenthal PJ, Cooper RA, Palmer M, Parkinson T, Burrows JN, Uhlemann AC, Birkholtz LM, Small-Saunders JL, Duffy J, Fidock DA, Brown A, Gardner M, Baker DA. Inhibitors of malaria parasite cyclic nucleotide phosphodiesterases block asexual blood-stage development and mosquito transmission. Science advances 2024. PMID: 39642214
Luth MR, Godinez-Macias KP, Chen D, Okombo J, Thathy V, Cheng X, Daggupati S, Davies H, Dhingra SK, Economy JM, Edgar RCS, Gomez-Lorenzo MG, Istvan ES, Jado JC, LaMonte GM, Melillo B, Mok S, Narwal SK, Ndiaye T, Ottilie S, Palomo Diaz S, Park H, Peña S, Rocamora F, Sakata-Kato T, Small-Saunders JL, Summers RL, Tumwebaze PK, Vanaerschot M, Xia G, Yeo T, You A, Gamo FJ, Goldberg DE, Lee MCS, McNamara CW, Ndiaye D, Rosenthal PJ, Schreiber SL, Serra G, De Siqueira-Neto JL, Skinner-Adams TS, Uhlemann AC, Kato N, Lukens AK, Wirth DF, Fidock DA, Winzeler EA. Systematic in vitro evolution in Plasmodium falciparum reveals key determinants of drug resistance. Science (New York, N.Y.) 2024. PMID: 39607932
Okitwi M, Shoue DA, Checkley LA, Orena S, Ceja FG, Taremwa Y, Tumwebaze PK, Katairo T, Byaruhanga O, Sievert MA, Garg S, Kreutzfeld OK, Legac J, Bailey JA, Nsobya SL, Conrad MD, Rosenthal PJ, Ferdig MT, Cooper RA. The extended recovery ring-stage survival assay is a scalable alternative for artemisinin susceptibility phenotyping of fresh Plasmodium falciparum isolates. Antimicrobial agents and chemotherapy 2024. PMID: 39545737
Lebel PM, Jeyakumar I, Khoo MWL, Charlton C, Saxena A, Jacobsen A, James E, Huynh E, Wu W, Courville G, Fu PC, Raghavan M, Puccinelli R, Peter O, Dorsey G, Rosenthal P, DeRisi J, Gomez-Sjoberg R. Remoscope: a label-free imaging cytometer for malaria diagnostics. medRxiv : the preprint server for health sciences 2024. PMID: 39606416
Kumar A, Li Y, Dodean RA, Roth A, Caridha D, Madejczyk MS, Jin X, Dennis WE, Lee PJ, Pybus BS, Martin M, Pannone K, Dinh HT, Blount C, Chetree R, DeLuca J, Evans M, Nadeau R, Vuong C, Leed S, Black C, Sousa J, Nolan C, Ceja FG, Rasmussen SA, Tumwebaze PK, Rosenthal PJ, Cooper RA, Rottmann M, Orjuela-Sanchez P, Meister S, Winzeler EA, Delves MJ, Matthews H, Baum J, Kirby RW, Burrows JN, Duffy J, Peyton DH, Reynolds KA, Kelly JX, Kancharla P. Tambjamines as Fast-Acting Multistage Antimalarials. ACS infectious diseases 2024. PMID: 39526703
Rosenthal PJ. Refugees. The American journal of tropical medicine and hygiene 2024. PMID: 39499950
Tukwasibwe S, Lewis SN, Taremwa Y, van der Ploeg K, Press KD, Ty M, Namirimu Nankya F, Musinguzi K, Nansubuga E, Bach F, Chamai M, Okitwi M, Tumusiime G, Nakimuli A, Colucci F, Kamya MR, Nankabirwa JI, Arinaitwe E, Greenhouse B, Dorsey G, Rosenthal PJ, Ssewanyana I, Jagannathan P. Natural killer cell antibody-dependent cellular cytotoxicity to Plasmodium falciparum is impacted by cellular phenotypes, erythrocyte polymorphisms, parasite diversity and intensity of transmission. Clinical & translational immunology 2024. PMID: 39493859
Zumla A, Rosenthal PJ, Sam-Agudu NA, Ogoina D, Mbala-Kingebeni P, Ntoumi F, Nakouné E, Njouom R, Ndembi N, Mills EJ, Muyembe-Tamfum JJ, Nachega JB. The 2024 Public Health Emergency of International Concern: A Global Failure to Control Mpox. The American journal of tropical medicine and hygiene 2024. PMID: 39406210
Mwebaza N, Roh ME, Geng YZ, Opio L, Opira B, Marzan F, Mwima MW, Ssemukuye T, Guo K, Gingrich D, Fotaki N, Kakuru A, Kizza J, Aguti M, Adrama H, Kamya M, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. Drug-Drug Interaction Between Dihydroartemisinin-Piperaquine and Sulfadoxine-Pyrimethamine During Malaria Chemoprevention in Pregnant Women. Clinical pharmacology and therapeutics 2024. PMID: 39402742
Jacobson KB, Röltgen K, Lam B, Nayebare P, Kakuru A, Kizza J, Aguti M, Nankya F, Briggs J, Takahashi S, Greenhouse B, Rodriguez-Barraquer I, van der Ploeg K, Wohlstadter JN, Sigal GB, Roh ME, Nankabirwa JI, Cuu G, Gaw SL, Rosenthal PJ, Kamya MR, Ssewanyana I, Dorsey G, Boyd SD, Jagannathan P. Gestational SARS-CoV-2 Infection in a Ugandan Birth Cohort: High Incidence, Mild Maternal Disease, and Evidence of Association with Transient Infant Stunting. The American journal of tropical medicine and hygiene 2024. PMID: 39288758
Jain AK, Busgang SA, Gennings C, Yates KP, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Carpenter D, Fishbein M, Neuschwander-Tetri BA, Tonasia J, Vos MB. Environmental toxicants modulate disease severity in pediatric metabolic dysfunction-associated steatohepatitis. Journal of pediatric gastroenterology and nutrition 2024. PMID: 39282813
Klope MT, Tapia Cardona JA, Chen J, Gonciarz RL, Cheng K, Jaishankar P, Kim J, Legac J, Rosenthal PJ, Renslo AR. Synthesis and In Vivo Profiling of Desymmetrized Antimalarial Trioxolanes with Diverse Carbamate Side Chains. ACS medicinal chemistry letters 2024. PMID: 39411530
Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, Jagannathan P, Rodriguez-Barraquer I, Dorsey G. Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda. PLOS global public health 2024. PMID: 39208072
Tukwasibwe S, Garg S, Katairo T, Asua V, Kagurusi BA, Mboowa G, Crudale R, Tumusiime G, Businge J, Alula D, Kasozi J, Wadembere I, Ssewanyana I, Arinaitwe E, Nankabirwa JI, Nsobya SL, Kamya MR, Greenhouse B, Dorsey G, Bailey JA, Briggs J, Conrad MD, Rosenthal PJ. Varied Prevalence of Antimalarial Drug Resistance Markers in Different Populations of Newly Arrived Refugees in Uganda. The Journal of infectious diseases 2024. PMID: 38874098
Kreutzfeld O, Orena S, Okitwi M, Tumwebaze PK, Byaruhanga O, Katairo T, Conrad MD, Legac J, Garg S, Crudale R, Aydemir O, Giesbrecht D, Nsobya SL, Blasco B, Duffey M, Rouillier M, Bailey JA, Cooper RA, Rosenthal PJ. Ex vivo susceptibilities to ganaplacide and diversity in potential resistance mediators in Ugandan Plasmodium falciparum isolates. Antimicrobial agents and chemotherapy 2024. PMID: 39136468
Dhorda M, Kaneko A, Komatsu R, Kc A, Mshamu S, Gesase S, Kapologwe N, Assefa A, Opigo J, Adoke Y, Ebong C, Karema C, Uwimana A, Mangara JN, Amaratunga C, Peto TJ, Tripura R, Callery JJ, Adhikari B, Mukaka M, Cheah PY, Mutesa L, Day NPJ, Barnes KI, Dondorp A, Rosenthal PJ, White NJ, von Seidlein L. Artemisinin-resistant malaria in Africa demands urgent action. Science (New York, N.Y.) 2024. PMID: 39024426
Ishengoma DS, Gosling R, Martinez-Vega R, Beshir KB, Bailey JA, Chimumbwa J, Sutherland C, Conrad MD, Tadesse FG, Juliano JJ, Kamya MR, Mbacham WF, Ménard D, Rosenthal PJ, Raman J, Tatarsky A, Tessema SK, Fidock DA, Djimde AA. Urgent action is needed to confront artemisinin partial resistance in African malaria parasites. Nature medicine 2024. PMID: 38710833
Ozarslan N, Robinson JF, Buarpung S, Kim MY, Ansbro MR, Akram J, Montoya DJ, Kamya MR, Kakuru A, Dorsey G, Rosenthal PJ, Cheng G, Feeney ME, Fisher SJ, Gaw SL. Gravidity influences distinct transcriptional profiles of maternal and fetal placental macrophages at term. Frontiers in immunology 2024. PMID: 38994356
Rosenthal PJ, Asua V, Conrad MD. Author Correction: Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa. Nature reviews. Microbiology 2024. PMID: 38413816
Nachega JB, Sam-Agudu NA, Ogoina D, Mbala-Kingebeni P, Ntoumi F, Nakouné E, Njouom R, Lewis RF, Gandhi M, Rosenthal PJ, Rawat A, Wilson LA, Kindrachuk J, Liesenborghs L, Mills EJ, Preiser W, Rimoin AW, Sullivan NJ, Peeters M, Delaporte E, Baxter C, Harrison L, Hermans MP, Mohr EL, Gonsalves G, Ndembi N, Zumla A, Muyembe-Tamfum JJ, Mpox Research Consortium. The surge of mpox in Africa: a call for action. The Lancet. Global health 2024. PMID: 38735300
Ovchinsky N, Aumar M, Baker A, Baumann U, Bufler P, Cananzi M, Czubkowski P, Durmaz Ö, Fischer R, Indolfi G, Karnsakul WW, Lacaille F, Lee WS, Maggiore G, Rosenthal P, Ruiz M, Sokal E, Sturm E, van der Woerd W, Verkade HJ, Wehrman A, Clemson C, Yu Q, Ni Q, Ruvido J, Manganaro S, Mattsson JP. Efficacy and safety of odevixibat in patients with Alagille syndrome (ASSERT): a phase 3, double-blind, randomised, placebo-controlled trial. The lancet. Gastroenterology & hepatology 2024. PMID: 38670135
Jonas MM, Romero R, Rosenthal P, Lin CH, Verucchi G, Wen J, Balistreri WF, Whitworth S, Bansal S, Leung DH, Narkewicz MR, Gonzalez-Peralta RP, Mangia A, Karnsakul W, Rao GS, Shao J, de Jong J, Parhy B, Osinusi A, Kersey K, Murray KF, Sokal EM, Schwarz KB. Sofosbuvir-velpatasvir in children 3-17 years old with hepatitis C virus infection. Journal of pediatric gastroenterology and nutrition 2024. PMID: 38644678
Di Chio C, Starvaggi J, Totaro N, Previti S, Natale B, Cosconati S, Bogacz M, Schirmeister T, Legac J, Rosenthal PJ, Zappalà M, Ettari R. Development of Novel Peptidyl Nitriles Targeting Rhodesain and Falcipain-2 for the Treatment of Sleeping Sickness and Malaria. International journal of molecular sciences 2024. PMID: 38673995
Rosenthal PJ, Asua V, Bailey JA, Conrad MD, Ishengoma DS, Kamya MR, Rasmussen C, Tadesse FG, Uwimana A, Fidock DA. The emergence of artemisinin partial resistance in Africa: how do we respond? The Lancet. Infectious diseases 2024. PMID: 38552654
Kamya MR, Nankabirwa JI, Arinaitwe E, Rek J, Zedi M, Maiteki-Sebuguzi C, Opigo J, Staedke SG, Oruni A, Donnelly MJ, Greenhouse B, Briggs J, Krezanoski PJ, Bousema T, Rosenthal PJ, Olwoch P, Jagannathan P, Rodriguez-Barraquer I, Dorsey G. Dramatic resurgence of malaria after 7 years of intensive vector control interventions in Eastern Uganda. medRxiv : the preprint server for health sciences 2024. PMID: 38559091
Maxwell SL, Price JC, Perito ER, Rosenthal P, Wojcicki JM. Food insecurity is a risk factor for metabolic dysfunction-associated steatotic liver disease in Latinx children. Pediatric obesity 2024. PMID: 38453472
Pandurangi S, Mourya R, Nalluri S, Fei L, Dong S, Harpavat S, Guthery SL, Molleston JP, Rosenthal P, Sokol RJ, Wang KS, Ng V, Alonso EM, Hsu EK, Karpen SJ, Loomes KM, Magee JC, Shneider BL, Horslen SP, Teckman JH, Bezerra JA, and the Childhood Liver Disease Research Network. Diagnostic accuracy of serum matrix metalloproteinase-7 as a biomarker of biliary atresia in a large North American cohort. Hepatology (Baltimore, Md.) 2024. PMID: 38446707
Somé AF, Conrad MD, Kabré Z, Fofana A, Yerbanga RS, Bazié T, Neya C, Somé M, Kagambega TJ, Legac J, Garg S, Bailey JA, Ouédraogo J-B, Rosenthal PJ, Cooper RA. Ex vivo drug susceptibility and resistance mediating genetic polymorphisms of Plasmodium falciparum in Bobo-Dioulasso, Burkina Faso. Antimicrobial agents and chemotherapy 2024. PMID: 38411062
Himes R, Rosenthal P, Dilwali N, Smith K, Venick R, Gonzalez-Peralta RP. Real-world experience of maralixibat in Alagille syndrome: Novel findings outside of clinical trials. Journal of pediatric gastroenterology and nutrition 2024. PMID: 38334237
Rosenthal PJ, Asua V, Conrad MD. Emergence, transmission dynamics and mechanisms of artemisinin partial resistance in malaria parasites in Africa. Nature reviews. Microbiology 2024. PMID: 38321292
Meier-Scherling CPG, Watson OJ, Asua V, Ghinai I, Katairo T, Garg S, Conrad M, Rosenthal PJ, Okell LC, Bailey JA. Selection of artemisinin partial resistance Kelch13 mutations in Uganda in 2016-22 was at a rate comparable to that seen previously in South-East Asia. medRxiv : the preprint server for health sciences 2024. PMID: 38352505
Sok V, Marzan F, Roh M, Guo K, Legac J, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. Determination of sulfadoxine and pyrimethamine in microvolume human plasma using ultra high performance liquid chromatography-tandam mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2024. PMID: 38309043
Wang L, Bohmer MJ, Wang J, Nardella F, Calla J, Laureano De Souza M, Schindler KA, Montejo L, Mittal N, Rocamora F, Treat M, Charlton JT, Tumwebaze PK, Rosenthal PJ, Cooper RA, Chakrabarti R, Winzeler EA, Chakrabarti D, Gray NS. Discovery of Potent Antimalarial Type II Kinase Inhibitors with Selectivity over Human Kinases. Journal of medicinal chemistry 2024. PMID: 38214254
Van Hove JLK, Friederich MW, Strode DK, Van Hove RA, Miller KR, Sharma R, Shah H, Estrella J, Gabel L, Horslen S, Kohli R, Lovell MA, Miethke AG, Molleston JP, Romero R, Squires JE, Alonso EM, Guthery SL, Kamath BM, Loomes KM, Rosenthal P, Mysore KR, Cavallo LA, Valentino PL, Magee JC, Sundaram SS, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases. Hepatology communications 2024. PMID: 38180987
Cheng K, Rosenthal P. Diagnosis and management of Alagille and progressive familial intrahepatic cholestasis. Hepatology communications 2023. PMID: 38055640
Teckman J, Rosenthal P, Ignacio RV, Spino C, Bass LM, Horslen S, Wang K, Magee JC, Karpen S, Asai A, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Shneider BL, Sokol RJ, ChiLDReN (Childhood Liver Disease Research Network). Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance. Hepatology communications 2023. PMID: 38055647
Jain AK, Buchannan P, Yates KP, Belt P, Schwimmer JB, Rosenthal P, Murray KF, Molleston JP, Scheimann A, Xanthakos SA, Behling CA, Hertel P, Nilson J, Neuschwander-Tetri BA, Tonascia J, Vos MB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Nutrition assessment and MASH severity in children using the Healthy Eating Index. Hepatology communications 2023. PMID: 38055641
Pal K, Lala S, Agarwal P, Patel TS, Legac J, Rahman MA, Ahmedi S, Shahid N, Singh S, Kumari K, Madhav H, Sen A, Manzoor N, Dixit BC, Van Zyl R, Rosenthal PJ, Hoda N. Naphthyl bearing 1,3,4-thiadiazoleacetamides targeting the parasitic folate pathway as anti-infectious agents: in silico, synthesis, and biological approach. RSC Medicinal Chemistry 2023. PMID: 38107179
Boster JM, Goodrich NP, Spino C, Loomes KM, Alonso EM, Kamath BM, Sokol RJ, Karpen S, Miethke A, Shneider BL, Molleston JP, Kohli R, Horslen SP, Rosenthal P, Valentino PL, Teckman JH, Hangartner TN, Sundaram SS, Childhood Liver Disease Research Network (ChiLDReN). Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease. Hepatology communications 2023. PMID: 37902507
Roh ME, Zongo I, Haro A, Huang L, Somé AF, Yerbanga RS, Conrad MD, Wallender E, Legac J, Aweeka F, Ouédraogo JB, Rosenthal PJ. Seasonal malaria chemoprevention drug levels and drug resistance markers in children with or without malaria in Burkina Faso: a case control study. The Journal of infectious diseases 2023. PMID: 37221018
Ozarslan N, Robinson JF, Buarpung S, Kim MY, Ansbro MR, Akram J, Montoya DJ, Kamya MR, Kakuru A, Dorsey G, Rosenthal PJ, Cheng G, Feeney ME, Fisher SJ, Gaw SL. Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity. bioRxiv : the preprint server for biology 2023. PMID: 37808856
Schwarzenberg SJ, King WC, Ling SC, Murray KF, Mogul D, Rosenthal P, Rodriguez-Baez N, Teckman J, Schwarz KB, Hepatitis B Research Network (HBRN). Change in Health-related Quality of Life in Youth with Chronic Hepatitis B Living in North America:A 5-year Cohort Study. Journal of pediatric gastroenterology and nutrition 2023. PMID: 37756340
Kirosingh AS, Delmastro A, Kakuru A, van der Ploeg K, Bhattacharya S, Press KD, Ty M, Parte L, Kizza J, Muhindo M, Devachanne S, Gamain B, Nankya F, Musinguzi K, Rosenthal PJ, Feeney ME, Kamya M, Dorsey G, Jagannathan P. Malaria-specific Type 1 regulatory T cells are more abundant in first pregnancies and associated with placental malaria. EBioMedicine 2023. PMID: 37634385
Conrad MD, Asua V, Garg S, Giesbrecht D, Niaré K, Smith S, Namuganga JF, Katairo T, Legac J, Crudale RM, Tumwebaze PK, Nsobya SL, Cooper RA, Kamya MR, Dorsey G, Bailey JA, Rosenthal PJ. Evolution of Partial Resistance to Artemisinins in Malaria Parasites in Uganda. The New England journal of medicine 2023. PMID: 37611122
Nachega JB, Mbala-Kingebeni P, Rosenthal PJ, Rimoin AW, Hoff NA, Liesenborghs L, Vanlerberghe V, Andrei G, Rawat A, Wilson LA, Forrest J, Mills EJ, Hermans MP, Mulangu S, Ntoumi F, Zumla A, Muyembe-Tamfum JJ. The Human Mpox Global Outbreak: Available Control Tools and the Opportunity to Break a Cycle of Neglect in Endemic Countries. The American journal of tropical medicine and hygiene 2023. PMID: 37580027
Rosenthal PJ. Proteasome inhibitors: The next generation of antimalarial drugs? Cell chemical biology 2023. PMID: 37207628
Squires JE, Miethke AG, Valencia CA, Hawthorne K, Henn L, Van Hove JLK, Squires RH, Bove K, Horslen S, Kohli R, Molleston JP, Romero R, Alonso EM, Bezerra JA, Guthery SL, Hsu E, Karpen SJ, Loomes KM, Ng VL, Rosenthal P, Mysore K, Wang KS, Friederich MW, Magee JC, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children. Hepatology communications 2023. PMID: 37184518
Ghany MG, Belle SH, Kleiner DE, Smith C, Kelley SS, Rosenthal P, Fontana RJ, Hepatitis B Research Network. Safety and yield of percutaneous liver biopsy in adults and children with chronic hepatitis B: Results from a prospective, multicenter study. Hepatology communications 2023. PMID: 37184524
Kreutzfeld O, Tumwebaze PK, Okitwi M, Orena S, Byaruhanga O, Katairo T, Conrad MD, Rasmussen SA, Legac J, Aydemir O, Giesbrecht D, Forte B, Campbell P, Smith A, Kano H, Nsobya SL, Blasco B, Duffey M, Bailey JA, Cooper RA, Rosenthal PJ. Susceptibility of Ugandan Plasmodium falciparum Isolates to the Antimalarial Drug Pipeline. Microbiology spectrum 2023. PMID: 37158739
Previti S, Ettari R, Di Chio C, Legac J, Bogacz M, Zimmer C, Schirmeister T, Rosenthal PJ, Zappalà M. Influence of amino acid size at the P3 position of N-Cbz-tripeptide Michael acceptors targeting falcipain-2 and rhodesain for the treatment of malaria and human african trypanosomiasis. Bioorganic chemistry 2023. PMID: 37163812
Blank BR, Gut J, Rosenthal PJ, Renslo AR. Artefenomel Regioisomer RLA-3107 Is a Promising Lead for the Discovery of Next-Generation Endoperoxide Antimalarials. ACS medicinal chemistry letters 2023. PMID: 37077383
Wojcicki JM, Gill RM, Wilson L, Lin J, Rosenthal P. Shorter leukocyte telomere length protects against NAFLD progression in children. Scientific Reports 2023. PMID: 37012261
Hong H, Aslam-Mir U, Kajubi R, Wallender E, Mwebaza N, Dorsey G, Rosenthal PJ, Aweeka FT, Huang L. Efavirenz-Based Antiretroviral Therapy but Not Pregnancy Increased Unbound Piperaquine Exposure in Women during Malaria Chemoprevention. Antimicrobial agents and chemotherapy 2023. PMID: 36916944
Harpavat S, Hawthorne K, Setchell KDR, Rivas MN, Henn L, Beil CA, Karpen SJ, Ng VL, Alonso EM, Bezerra JA, Guthery SL, Horslen S, Loomes KM, McKiernan P, Magee JC, Merion RM, Molleston JP, Rosenthal P, Thompson RJ, Wang KS, Sokol RJ, Shneider BL, for Childhood Liver Disease Research Network (ChiLDReN). Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy. Hepatology (Baltimore, Md.) 2022. PMID: 36131538
Gonzalez-Peralta RP, Wirth S, Squires RH, Mutschler F, Lang T, Pawlowska M, Sluzewski W, Majda-Stanislawska E, Fischler B, Balistreri WF, Jonas MM, Blondet N, Rosenthal P, Alkhouri N, Romero R, Grandhi A, Castronuovo P, Caro L, Du L, Rosenbloom DIS, Haber BA. Elbasvir/grazoprevir in children aged 3-18 years with chronic HCV genotype 1 or 4 infection: a pharmacokinetic modeling study. Hepatology communications 2023. PMID: 36790337
Miloh T, Goldstein A, Howard R, Mogul DB, Marden JR, Anderson A, Gaburo K, Kirson N, Rosenthal P. Costs of pediatric liver transplantation among commercially- and medicaid-insured patients with cholestasis in the United States. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2023. PMID: 36747344
Briggs J, Takahashi S, Nayebare P, Cuu G, Rek J, Zedi M, Kizza T, Arinaitwe E, Nankabirwa JI, Kamya M, Jagannathan P, Jacobson K, Rosenthal PJ, Dorsey G, Greenhouse B, Ssewanyana I, Rodríguez-Barraquer I. Seroprevalence of Antibodies to SARS-CoV-2 in Rural Households in Eastern Uganda, 2020-2022. JAMA network open 2023. PMID: 36790811
Zhang H, Ginn J, Zhan W, Leung A, Liu YJ, Toita A, Okamoto R, Wong TT, Imaeda T, Hara R, Michino M, Yukawa T, Chelebieva S, Tumwebaze PK, Vendome J, Beuming T, Sato K, Aso K, Rosenthal PJ, Cooper RA, Liverton N, Foley M, Meinke PT, Nathan CF, Kirkman LA, Lin G. Structure-Activity Relationship Studies of Antimalarial Plasmodium Proteasome Inhibitors─Part II. Journal of medicinal chemistry 2023. PMID: 36630286
Nankabirwa JI, Bousema T, Blanken SL, Rek J, Arinaitwe E, Greenhouse B, Rosenthal PJ, Kamya MR, Staedke SG, Dorsey G. Measures of malaria transmission, infection, and disease in an area bordering two districts with and without sustained indoor residual spraying of insecticide in Uganda. PloS one 2022. PMID: 36584122
Pal K, Raza MK, Legac J, Rahman A, Manzoor S, Bhattacharjee S, Rosenthal PJ, Hoda N. Identification, in-vitro anti-plasmodial assessment and docking studies of series of tetrahydrobenzothieno[2,3-d]pyrimidine-acetamide molecular hybrids as potential antimalarial agents. European journal of medicinal chemistry 2022. PMID: 36621136
Nachega JB, Nsanzimana S, Rawat A, Wilson LA, Rosenthal PJ, Siedner MJ, Varma JK, Kilmarx PH, Mutesa L, Tanner M, Binagwaho A, Forrest J, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Ntoumi F, Zumla A, de Oliveira T, Mills EJ. Advancing detection and response capacities for emerging and re-emerging pathogens in Africa. The Lancet. Infectious diseases 2022. PMID: 36563700
Mawejje HD, Asiimwe JR, Kyagamba P, Kamya MR, Rosenthal PJ, Lines J, Dorsey G, Staedke SG. Impact of different mosquito collection methods on indicators of Anopheles malaria vectors in Uganda. Malaria journal 2022. PMID: 36536428
Mawejje HD, Weetman D, Epstein A, Lynd A, Opigo J, Maiteki-Sebuguzi C, Lines J, Kamya MR, Rosenthal PJ, Donnelly MJ, Dorsey G, Staedke SG. Characterizing pyrethroid resistance and mechanisms in Anopheles gambiae (s.s.) and Anopheles arabiensis from 11 districts in Uganda. Current research in parasitology & vector-borne diseases 2022. PMID: 36590346
Sharma B, Chowdhary S, Legac J, Rosenthal PJ, Kumar V. Quinoline-based heterocyclic hydrazones: Design, synthesis, anti-plasmodial assessment, and mechanistic insights. Chemical biology & drug design 2022. PMID: 36418231
Nachega JB, Sam-Agudu NA, Machekano RN, Rosenthal PJ, Schell S, de Waard L, Bekker A, Gachuno OW, Kinuthia J, Mwongeli N, Budhram S, Vannevel V, Somapillay P, Prozesky HW, Taljaard J, Parker A, Agyare E, Opoku AB, Makarfi AU, Abdullahi AM, Adirieje C, Ishoso DK, Pipo MT, Tshilanda MB, Bongo-Pasi Nswe C, Ditekemena J, Sigwadhi LN, Nyasulu PS, Hermans MP, Sekikubo M, Musoke P, Nsereko C, Agbeno EK, Yeboah MY, Umar LW, Ntakwinja M, Mukwege DM, Birindwa EK, Mushamuka SZ, Smith ER, Mills EJ, Otshudiema JO, Mbala-Kingebeni P, Tamfum JM, Zumla A, Tsegaye A, Mteta A, Sewankambo NK, Suleman F, Adejumo P, Anderson JR, Noormahomed EV, Deckelbaum RJ, Stringer JSA, Mukalay A, Taha TE, Fowler MG, Wasserheit JN, Masekela R, Mellors JW, Siedner MJ, Myer L, Kengne AP, Yotebieng M, Mofenson LM, Langenegger E, AFREhealth Research Collaboration on COVID-19 and Pregnancy. Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Pregnancy in Sub-Saharan Africa: A 6-Country Retrospective Cohort Analysis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022. PMID: 36130257
Rosenthal PJ. Response to "The Importance of Exercising Caution When Comparing Results from Malaria Vaccines Administered on the EPI Schedule and on a Seasonal Schedule". The American journal of tropical medicine and hygiene 2022. PMID: 36410330
Felzen A, van Wessel DBE, Gonzales E, Thompson RJ, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering D, Nicastro E, Kelly D, Nebbia G, Arnell H, Fischler B, Hulscher JBF, Serranti D, Arikan C, Polat E, Debray D, Lacaille F, Goncalves C, Hierro L, Mu?oz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsofi A, Calvo PL, Grabhorn E, Hartleif S, van der Woerd WJ, Kamath BM, Wang JS, Li L, Durmaz ?, Kerkar N, J?rgensen MH, Fischer R, Jimenez-Rivera C, Alam S, Cananzi M, Laverdure N, Ferreira CT, Guerrero FO, Wang H, Sency V, Kim KM, Chen HL, de Carvalho E, Fabre A, Bernabeu JQ, Zellos A, Alonso EM, Sokol RJ, Suchy FJ, Loomes KM, McKiernan PJ, Rosenthal P, Turmelle Y, Horslen S, Schwarz K, Bezerra JA, Wang K, Hansen BE, Verkade HJ, NAtural course and Prognosis of PFIC and Effect of biliary Diversion (NAPPED) Consortium. Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency. JHEP reports : innovation in hepatology 2022. PMID: 36687469
Leung DH, Devaraj S, Goodrich NP, Chen X, Rajapakshe D, Ye W, Andreev V, Minard CG, Guffey D, Molleston JP, Bass LM, Karpen SJ, Kamath BM, Wang KS, Sundaram SS, Rosenthal P, McKiernan P, Loomes KM, Jensen MK, Horslen SP, Bezerra JA, Magee JC, Merion RM, Sokol RJ, Shneider BL, Alonso E, Bass L, Kelly S, Riordan M, Melin-Aldana H, Bezerra J, Bove K, Heubi J, Miethke A, Tiao G, Denlinger J, Chapman E, Sokol R, Feldman A, Mack C, Narkewicz M, Suchy F, Sundaram SS, Van Hove J, Garcia B, Kauma M, Kocher K, Steinbeiss M, Lovell M, Loomes KM, Piccoli D, Rand E, Russo P, Spinner N, Erlichman J, Stalford S, Pakstis D, King S, Squires R, Sindhi R, Venkat V, Bukauskas K, McKiernan P, Haberstroh L, Squires J, Rosenthal P, Bull L, Curry J, Langlois C, Kim G, Teckman J, Kociela V, Nagy R, Patel S, Cerkoski J, Molleston JP, Bozic M, Subbarao G, Klipsch A, Sawyers C, Cummings O, Horslen SP, Murray K, Hsu E, Cooper K, Young M, Finn L, Kamath BM, Ng V, Quammie C, Putra J, Sharma D, Parmar A, Guthery S, Jensen K, Rutherford A, Lowichik A, Book L, Meyers R, Hall T, Wang KS, Michail S, Thomas D, Goodhue C, Kohli R, Wang L, Soufi N, Thomas D, Karpen S, Gupta N, Romero R, Vos MB, Tory R, Berauer JP, Abramowsky C, McFall J, Shneider BL, Harpavat S, Hertel P, Leung D, Tessier M, Schady D, Cavallo L, Olvera D, Banks C, Tsai C, Thompson R, Doo E, Hoofnagle J, Sherker A, Torrance R, Hall S, Magee J, Merion R, Spino C, Ye W, Childhood Liver Disease Research Network. Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease. Hepatology (Baltimore, Md.) 2022. PMID: 36069569
Tumwebaze PK, Conrad MD, Okitwi M, Orena S, Byaruhanga O, Katairo T, Legac J, Garg S, Giesbrecht D, Smith SR, Ceja FG, Nsobya SL, Bailey JA, Cooper RA, Rosenthal PJ. Decreased susceptibility of Plasmodium falciparum to both dihydroartemisinin and lumefantrine in northern Uganda. Nature communications 2022. PMID: 36289202
Nachega JB, Sam-Agudu NA, Siedner MJ, Rosenthal PJ, Mellors JW, Zumla A, Hermans MP, Ntakwinja MB, Mukwege DM, Langenegger E, Mofenson LM, African Forum for Research and Education in Health (AFREhealth) Research Collaboration on COVID-19 a. Prioritizing Pregnant Women for Coronavirus Disease 2019 Vaccination in African Countries. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2022. PMID: 36130226
Namuganga JF, Nankabirwa JI, Maiteki-Ssebuguzi C, Gonahasa S, Opigo J, Staedke SG, Rutazaana D, Ebong C, Dorsey G, Tomko SS, Kizza T, Mawejje HD, Arinaitwe E, Rosenthal PJ, Kamya MR. East Africa International Center of Excellence for Malaria Research: Impact on Malaria Policy in Uganda. The American journal of tropical medicine and hygiene 2022. PMID: 36228904
Nankabirwa JI, Rek J, Arinaitwe E, Namuganga JF, Nsobya SL, Asua V, Mawejje HD, Epstein A, Greenhouse B, Rodriguez-Barraquer I, Briggs J, Krezanoski PJ, Rosenthal PJ, Conrad M, Smith D, Staedke SG, Drakeley C, Bousema T, Andolina C, Donnelly MJ, Kamya MR, Dorsey G. East Africa International Center of Excellence for Malaria Research: Summary of Key Research Findings. The American journal of tropical medicine and hygiene 2022. PMID: 36228916
Nankabirwa JI, Arinaitwe E, Briggs J, Rek J, Rosenthal PJ, Kamya MR, Olwoch P, Smith DL, Rodriguez-Barraquer I, Dorsey G, Greenhouse B. Simulating the Impacts of Augmenting Intensive Vector Control with Mass Drug Administration or Test-and-Treat Strategies on the Malaria Infectious Reservoir. The American journal of tropical medicine and hygiene 2022. PMID: 36191870
Ebel NH, Goldstein A, Howard R, Mogul DB, Marden JR, Anderson A, Gaburo K, Kirson N, Rosenthal P. Health care resource utilization by patients with Alagille syndrome. The Journal of pediatrics 2022. PMID: 36179890
Briggs J, Takahashi S, Nayebare P, Cuu G, Rek J, Zedi M, Kizza T, Arinaitwe E, Nankabirwa JI, Kamya M, Jagannathan P, Jacobson K, Rosenthal PJ, Dorsey G, Greenhouse B, Ssewanyana I, Rodríguez-Barraquer I. Reconstructing the SARS-CoV-2 epidemic in eastern Uganda through longitudinal serosurveillance in a malaria cohort. medRxiv : the preprint server for health sciences 2022. PMID: 36172117
Garg S, Kreutzfeld O, Chelebieva S, Tumwebaze PK, Byaruhanga O, Okitwi M, Orena S, Katairo T, Nsobya SL, Conrad MD, Aydemir O, Legac J, Gould AE, Bayles BR, Bailey JA, Duffey M, Lin G, Kirkman LA, Cooper RA, Rosenthal PJ. Susceptibilities of Ugandan Plasmodium falciparum Isolates to Proteasome Inhibitors. Antimicrobial agents and chemotherapy 2022. PMID: 36094216
Hughes E, Wallender E, Kajubi R, Jagannathan P, Ochieng T, Kakuru A, Kamya MR, Clark TD, Rosenthal PJ, Dorsey G, Aweeka F, Savic RM. Piperaquine induced QTc prolongation decreases with repeated monthly dihydroartemisinin-piperaquine dosing in pregnant Ugandan women. 2021. PMID: 34864925
Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P. The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca2+ Homeostasis by Targeting a Unique Ion Channel. Pharmaceutics 2022. PMID: 35890267
Rosenthal P. Advances in Pediatric Liver Diseases. Clinics in liver disease 2022. PMID: 35868690
Plucinski M, Ashley EA, Bassat Q, Venkatesan M, Rosenthal PJ, Halsey ES. STARTER Checklist for Antimalarial Therapeutic Efficacy Reporting. The American journal of tropical medicine and hygiene 2022. PMID: 35880678
Plucinski MM, Ashley EA, Bassat Q, Venkatesan M, Rosenthal PJ, Halsey ES. STARTER checklist for antimalarial therapeutic efficacy reporting. Malaria journal 2022. PMID: 35698123
Shneider BL, Spino CA, Kamath BM, Magee JC, Ignacio RV, Huang S, Horslen SP, Molleston JP, Miethke AG, Kohli R, Leung DH, Jensen MK, Loomes KM, Karpen SJ, Mack C, Rosenthal P, Squires RH, Baker A, Rajwal S, Kelly D, Sokol RJ, Thompson RJ, for ChiLDReN and UK IMAGO/IMAGINE Investigators. Impact of long-term administration of maralixibat on children with cholestasis secondary to Alagille syndrome. 2022. PMID: 35672955
Shneider BL, Kamath BM, Magee JC, Goodrich NP, Loomes KM, Ye W, Spino C, Alonso EM, Molleston JP, Bezerra JA, Wang KS, Karpen SJ, Horslen SP, Guthery SL, Rosenthal P, Squires RH, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases-Examination of cholestatic liver disease in Alagille syndrome. 2022. PMID: 35506349
de Vries LE, Jansen PAM, Barcelo C, Munro J, Verhoef JMJ, Pasaje CFA, Rubiano K, Striepen J, Abla N, Berning L, Bolscher JM, Demarta-Gatsi C, Henderson RWM, Huijs T, Koolen KMJ, Tumwebaze PK, Yeo T, Aguiar ACC, Angulo-Barturen I, Churchyard A, Baum J, Fernández BC, Fuchs A, Gamo FJ, Guido RVC, Jiménez-Diaz MB, Pereira DB, Rochford R, Roesch C, Sanz LM, Trevitt G, Witkowski B, Wittlin S, Cooper RA, Rosenthal PJ, Sauerwein RW, Schalkwijk J, Hermkens PHH, Bonnert RV, Campo B, Fidock DA, Llinás M, Niles JC, Kooij TWA, Dechering KJ. Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183. Nature communications 2022. PMID: 35444200
Bass LM, Ye W, Hawthorne K, Leung DH, Murray KF, Molleston JP, Romero R, Karpen S, Rosenthal P, Loomes KM, Wang KS, Squires RH, Miethke A, Ng VL, Horslen S, Jensen MK, Sokol RJ, Magee JC, Shneider BL, ChiLDReN. The Risk of Variceal Hemorrhage and Pre-Transplant Mortality in Children with Biliary Atresia. 2022. PMID: 35271743
Rosenthal PJ, Björkman A, Dhorda M, Djimde A, Dondorp AM, Gaye O, Guerin PJ, Juma E, Kwiatkowski DP, Merson L, Ntoumi F, Price RN, Raman J, Roos DS, Ter Kuile F, Tinto H, Tomko SS, White NJ, Barnes KI. Cooperation in Countering Artemisinin Resistance in Africa: Learning from COVID-19. The American journal of tropical medicine and hygiene 2022. PMID: 35413688
Das D, Vongpromek R, Assawariyathipat T, Srinamon K, Kennon K, Stepniewska K, Ghose A, Sayeed AA, Faiz MA, Netto RLA, Siqueira A, Yerbanga SR, Ouédraogo JB, Callery JJ, Peto TJ, Tripura R, Koukouikila-Koussounda F, Ntoumi F, Ong'echa JM, Ogutu B, Ghimire P, Marfurt J, Ley B, Seck A, Ndiaye M, Moodley B, Sun LM, Archasuksan L, Proux S, Nsobya SL, Rosenthal PJ, Horning MP, McGuire SK, Mehanian C, Burkot S, Delahunt CB, Bachman C, Price RN, Dondorp AM, Chappuis F, Guérin PJ, Dhorda M. Field evaluation of the diagnostic performance of EasyScan GO: a digital malaria microscopy device based on machine-learning. Malaria journal 2022. PMID: 35413904
Rosenthal PJ. Malaria in 2022: Challenges and Progress. The American journal of tropical medicine and hygiene 2022. PMID: 35413687
Khalili M, Kleiner DE, King WC, Sterling RK, Ghany MG, Chung RT, Bhan AK, Rosenthal P, Lisker-Melman M, Ramachandran R, Lok AS. Reply to Li, Henry, and Nguyen. 2022. PMID: 35158369
Lopes EA, Mestre R, Fontinha D, Legac J, Pei JV, Sanches-Vaz M, Mori M, Lehane AM, Rosenthal PJ, Prudêncio M, Santos MMM. Discovery of spirooxadiazoline oxindoles with dual-stage antimalarial activity. European journal of medicinal chemistry 2022. PMID: 35390711
Perrillo RP, Lin HS, Schwarz KB, Rosenthal P, Lisker-Melman M, Chung RT, Prokunina-Olsson L, Coherty G, Feld J, Hepatitis B Research Network (HBRN). Changes in serum hepatitis B surface and e antigen, IP-10, and aminotransferase levels during combination therapy of immune tolerant chronic hepatitis B. 2022. PMID: 35188674
Huang L, Sok V, Aslam-Mir U, Marzan F, Whalen M, Rosenthal PJ, Aweeka F. Determination of unbound piperaquine in human plasma by ultra-high performance liquid chromatography tandem mass spectrometry. 2022. PMID: 35531322
Okitwi M, Orena S, Thomas K, Tumwebaze PK, Byaruhanga O, Nsobya SL, Conrad MD, Bayles BR, Rosenthal PJ, Cooper RA. Impact of Short-Term Storage on Ex Vivo Antimalarial Susceptibilities of Fresh Ugandan Plasmodium falciparum Isolates. Antimicrobial agents and chemotherapy 2022. PMID: 35266828
Brinkmann S, Semmler S, Kersten C, Patras MA, Kurz M, Fuchs N, Hammerschmidt SJ, Legac J, Hammann PE, Vilcinskas A, Rosenthal PJ, Schirmeister T, Bauer A, Schäberle TF. Identification, Characterization, and Synthesis of Natural Parasitic Cysteine Protease Inhibitors: Pentacitidins Are More Potent Falcitidin Analogues. ACS chemical biology 2022. PMID: 35262340
Nachega JB, Sam-Agudu NA, Machekano RN, Rabie H, van der Zalm MM, Redfern A, Dramowski A, O'Connell N, Pipo MT, Tshilanda MB, Byamungu LN, Masekela R, Jeena PM, Pillay A, Gachuno OW, Kinuthia J, Ishoso DK, Amoako E, Agyare E, Agbeno EK, Martyn-Dickens C, Sylverken J, Enimil A, Jibril AM, Abdullahi AM, Amadi O, Umar UM, Sigwadhi LN, Hermans MP, Otokoye JO, Mbala-Kingebeni P, Muyembe-Tamfum JJ, Zumla A, Sewankambo NK, Aanyu HT, Musoke P, Suleman F, Adejumo P, Noormahomed EV, Deckelbaum RJ, Fowler MG, Tshilolo L, Smith G, Mills EJ, Umar LW, Siedner MJ, Kruger M, Rosenthal PJ, Mellors JW, Mofenson LM, African Forum for Research and Education in Health (AFREhealth) COVID-19 Research Collaboration on C. Assessment of Clinical Outcomes Among Children and Adolescents Hospitalized With COVID-19 in 6 Sub-Saharan African Countries. JAMA pediatrics 2022. PMID: 35044430
Taft BR, Yokokawa F, Kirrane T, Mata AC, Huang R, Blaquiere N, Waldron G, Zou B, Simon O, Vankadara S, Chan WL, Ding M, Sim S, Straimer J, Guiguemde A, Lakshminarayana SB, Jain JP, Bodenreider C, Thompson C, Lanshoeft C, Shu W, Fang E, Qumber J, Chan K, Pei L, Chen YL, Schulz H, Lim J, Abas SN, Ang X, Liu Y, Angulo-Barturen I, Jiménez-Díaz MB, Gamo FJ, Crespo-Fernandez B, Rosenthal PJ, Cooper RA, Tumwebaze P, Aguiar ACC, Campo B, Campbell S, Wagner J, Diagana TT, Sarko C. Discovery and Preclinical Pharmacology of INE963, a Potent and Fast-Acting Blood-Stage Antimalarial with a High Barrier to Resistance and Potential for Single-Dose Cures in Uncomplicated Malaria. Journal of medicinal chemistry 2022. PMID: 35229610
Kreutzfeld O, Tumwebaze PK, Byaruhanga O, Katairo T, Okitwi M, Orena S, Rasmussen SA, Legac J, Conrad MD, Nsobya SL, Aydemir O, Bailey JA, Duffey M, Cooper RA, Rosenthal PJ. Decreased susceptibility to dihydrofolate reductase inhibitors associated with genetic polymorphisms in Ugandan Plasmodium falciparum isolates. The Journal of infectious diseases 2021. PMID: 34460932
Johnson Valiente A, Liem KS, Schwarz KB, Rosenthal P, Murray KF, Mogul D, Teckman J, Rodriguez-Baez N, Schwarzenberg SJ, Feld JJ, Wong DK, Lewis-Ximenez LL, Lauer G, Hansen BE, Ling SC, Janssen HLA, Gehring AJ. The Inflammatory Cytokine Profile Associated with Liver Damage is Broader and Stronger in Chronic Hepatitis B Patients Compared to Acute Hepatitis B Patients. The Journal of infectious diseases 2021. PMID: 34286845
Terrault NA, Wahed AS, Feld JJ, Cooper SL, Ghany MG, Lisker-Melman M, Perrillo R, Sterling RK, Khalili M, Chung RT, Rosenthal P, Fontana RJ, Sarowar A, Lau DTY, Wang J, Lok AS, Janssen HLA. Incidence and prediction of HBsAg seroclearance in a prospective multi-ethnic HBeAg-negative chronic hepatitis B cohort. 2021. PMID: 34743343
Schwarzenberg SJ, Ling SC, Rosenthal P, Murray KF, Teckman J, Mogul D, Rodriguez-Baez N, Schwarz K. Lessons Learned from Children Enrolled into the Hepatitis B Virus Research Network Multi-Center Prospective Study. 2022. PMID: 35045562
Leung DH, Sorensen LG, Ye W, Hawthorne K, Ng VL, Loomes KM, Fredericks EM, Alonso EM, Heubi JE, Horslen SP, Karpen SJ, Molleston JP, Rosenthal P, Sokol RJ, Squires RH, Wang KS, Kamath BM, Magee JC, Childhood Liver Disease Research Network (ChiLDReN). Neurodevelopmental Outcomes in Children with Inherited Liver Disease and Native Liver. 2021. PMID: 34694263
Taylor SA, Venkat V, Arnon R, Gopalareddy VV, Rosenthal P, Anderson SG, Anand R, Daniel JF, Society of Pediatric Liver Transplantation. Organ-specific comorbidities are associated with distinct complications after liver transplantation for biliary atresia. 2021. PMID: 34821466
Fidock DA, Rosenthal PJ. Artemisinin resistance in Africa: How urgent is the threat? Med (New York, N.Y.) 2021. PMID: 35005674
Wallender E, Ali AM, Hughes E, Kakuru A, Jagannathan P, Muhindo MK, Opira B, Whalen M, Huang L, Duvalsaint M, Legac J, Kamya MR, Dorsey G, Aweeka F, Rosenthal PJ, Savic RM. Identifying an optimal dihydroartemisinin-piperaquine dosing regimen for malaria prevention in young Ugandan children. 2021. PMID: 34795281
Kanai M, Yeo T, Asua V, Rosenthal PJ, Fidock DA, Mok S. Comparative Analysis of Plasmodium falciparum Genotyping via SNP Detection, Microsatellite Profiling, and Whole-Genome Sequencing. Antimicrobial agents and chemotherapy 2021. PMID: 34694871
Hertel PM, Hawthorne K, Kim S, Finegold MJ, Shneider BL, Squires JE, Gupta NA, Bull LN, Murray KF, Kerkar N, Ng VL, Molleston JP, Bezerra JA, Loomes KM, Taylor SA, Schwarz KB, Turmelle YP, Rosenthal P, Magee JC, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Presentation and Outcomes of Infants with Idiopathic Cholestasis: A Multi-Center Prospective Study. Journal of pediatric gastroenterology and nutrition 2021. PMID: 34310436
Rosenthal PJ. Are Artemisinin-Based Combination Therapies For Malaria Beginning To Fail in Africa? The American journal of tropical medicine and hygiene 2021. PMID: 34491214
Cheng K, Rosenthal P, Roberts JP, Perito ER. Liver transplant in children and adults with cystic fibrosis: Impact of growth failure and nutritional status. American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2021. PMID: 34379865
Kreutzfeld O, Rasmussen SA, Ramanathan AA, Tumwebaze PK, Byaruhanga O, Katairo T, Asua V, Okitwi M, Orena S, Legac J, Conrad MD, Nsobya SL, Aydemir O, Bailey J, Duffey M, Bayles BR, Vaidya AB, Cooper RA, Rosenthal PJ. Associations between Varied Susceptibilities to PfATP4 Inhibitors and Genotypes in Ugandan Plasmodium falciparum Isolates. Antimicrobial agents and chemotherapy 2021. PMID: 34339273
Khalili M, Kleiner DE, King WC, Sterling RK, Ghany MG, Chung RT, Bhan AK, Rosenthal P, Lisker-Melman M, Ramachandran R, Lok AS, ; and the Hepatitis B Research Network (HBRN). Hepatic Steatosis and Steatohepatitis in a Large North American Cohort of Adults With Chronic Hepatitis B. The American journal of gastroenterology 2021. PMID: 33840726
Murithi JM, Pascal C, Bath J, Boulenc X, Gnädig NF, Pasaje CFA, Rubiano K, Yeo T, Mok S, Klieber S, Desert P, Jiménez-Díaz MB, Marfurt J, Rouillier M, Cherkaoui-Rbati MH, Gobeau N, Wittlin S, Uhlemann AC, Price RN, Wirjanata G, Noviyanti R, Tumwebaze P, Cooper RA, Rosenthal PJ, Sanz LM, Gamo FJ, Joseph J, Singh S, Bashyam S, Augereau JM, Giraud E, Bozec T, Vermat T, Tuffal G, Guillon JM, Menegotto J, Sallé L, Louit G, Cabanis MJ, Nicolas MF, Doubovetzky M, Merino R, Bessila N, Angulo-Barturen I, Baud D, Bebrevska L, Escudié F, Niles JC, Blasco B, Campbell S, Courtemanche G, Fraisse L, Pellet A, Fidock DA, Leroy D. The antimalarial MMV688533 provides potential for single-dose cures with a high barrier to Plasmodium falciparum parasite resistance. Science translational medicine 2021. PMID: 34290058
Stokes BH, Dhingra SK, Rubiano K, Mok S, Straimer J, Gnädig NF, Deni I, Schindler KA, Bath JR, Ward KE, Striepen J, Yeo T, Ross LS, Legrand E, Ariey F, Cunningham CH, Souleymane IM, Gansané A, Nzoumbou-Boko R, Ndayikunda C, Kabanywanyi AM, Uwimana A, Smith SJ, Kolley O, Ndounga M, Warsame M, Leang R, Nosten F, Anderson TJ, Rosenthal PJ, Ménard D, Fidock DA. Plasmodium falciparum K13 mutations in Africa and Asia impact artemisinin resistance and parasite fitness. eLife 2021. PMID: 34279219
van Wessel DBE, Thompson RJ, Gonzales E, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering D, Algoufi T, Mazhar N, Nicastro E, Kelly D, Nebbia G, Arnell H, Fischler B, Hulscher JBF, Serranti D, Arikan C, Debray D, Lacaille F, Goncalves C, Hierro L, Muñoz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsofi A, Luigi Calvo P, Krebs-Schmitt D, Hartleif S, van der Woerd WL, Wang JS, Li LT, Durmaz Ö, Kerkar N, Hørby Jørgensen M, Fischer R, Jimenez-Rivera C, Alam S, Cananzi M, Laverdure N, Targa Ferreira C, Ordonez F, Wang H, Sency V, Mo Kim K, Chen HL, Carvalho E, Fabre A, Quintero Bernabeu J, Alonso EM, Sokol RJ, Suchy FJ, Loomes KM, McKiernan PJ, Rosenthal P, Turmelle Y, Rao GS, Horslen S, Kamath BM, Rogalidou M, Karnsakul WW, Hansen B, Verkade HJ, Natural Course and Prognosis of PFIC and Effect of Biliary Diversion Consortium. Impact of Genotype, Serum Bile Acids, and Surgical Biliary Diversion on Native Liver Survival in FIC1 Deficiency. Hepatology (Baltimore, Md.) 2021. PMID: 33666275
Duvalsaint M, Conrad MD, Tukwasibwe S, Tumwebaze PK, Legac J, Cooper RA, Rosenthal PJ. Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum. Malaria journal 2021. PMID: 34193148
Ekusai-Sebatta D, Arinaitwe E, Mpimbaza A, Nankabirwa JI, Drakeley C, Rosenthal PJ, Staedke SG, Muyinda H. Challenges and opportunities for use of long-lasting insecticidal nets to prevent malaria during overnight travel in Uganda: a qualitative study. Malaria journal 2021. PMID: 34174892
Tumwebaze PK, Katairo T, Okitwi M, Byaruhanga O, Orena S, Asua V, Duvalsaint M, Legac J, Chelebieva S, Ceja FG, Rasmussen SA, Conrad MD, Nsobya SL, Aydemir O, Bailey JA, Bayles BR, Rosenthal PJ, Cooper RA. Drug susceptibility of Plasmodium falciparum in eastern Uganda: a longitudinal phenotypic and genotypic study. The Lancet. Microbe 2021. PMID: 34553183
Andolina C, Rek JC, Briggs J, Okoth J, Musiime A, Ramjith J, Teyssier N, Conrad M, Nankabirwa JI, Lanke K, Rodriguez-Barraquer I, Meerstein-Kessel L, Arinaitwe E, Olwoch P, Rosenthal PJ, Kamya MR, Dorsey G, Greenhouse B, Drakeley C, Staedke SG, Bousema T. Sources of persistent malaria transmission in a setting with effective malaria control in eastern Uganda: a longitudinal, observational cohort study. The Lancet. Infectious diseases 2021. PMID: 34146476
Ling SC, Lin HS, Murray KF, Rosenthal P, Mogul D, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Schwarz KB, Hepatitis B Research Network (HBRN). Chronic Hepatitis Is Common and Often Untreated Among Children with Hepatitis B Infection in the United States and Canada. The Journal of pediatrics 2021. PMID: 34022250
Pal K, Raza MK, Legac J, Ataur Rahman M, Manzoor S, Rosenthal PJ, Hoda N. Design, synthesis, crystal structure and anti-plasmodial evaluation of tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine derivatives. RSC Medicinal Chemistry 2021. PMID: 34223162
Lee AY, Lehrman ED, Perito ER, Kerlan RK, Kohi MP, Kolli KP, Taylor AG, Ostroff JW, Kang SM, Roberts JP, Rhee S, Rosenthal P, Fidelman N. Non-operative management of biliary complications after Liver Transplantation in pediatric patients: A 30-year experience. Pediatric transplantation 2021. PMID: 33951255
Karpen SJ, Kamath BM, Alexander JJ, Ichetovkin I, Rosenthal P, Sokol RJ, Dunn S, Thompson RJ, Heubi JE. Use of a Comprehensive 66-Gene Cholestasis Sequencing Panel in 2171 Cholestatic Infants, Children, and Young Adults. Journal of pediatric gastroenterology and nutrition 2021. PMID: 33720099
Palmer MJ, Deng X, Watts S, Krilov G, Gerasyuto A, Kokkonda S, El Mazouni F, White J, White KL, Striepen J, Bath J, Schindler KA, Yeo T, Shackleford DM, Mok S, Deni I, Lawong A, Huang A, Chen G, Wang W, Jayaseelan J, Katneni K, Patil R, Saunders J, Shahi SP, Chittimalla R, Angulo-Barturen I, Jiménez-Díaz MB, Wittlin S, Tumwebaze PK, Rosenthal PJ, Cooper RA, Aguiar ACC, Guido RVC, Pereira DB, Mittal N, Winzeler EA, Tomchick DR, Laleu B, Burrows JN, Rathod PK, Fidock DA, Charman SA, Phillips MA. Potent Antimalarials with Development Potential Identified by Structure-Guided Computational Optimization of a Pyrrole-Based Dihydroorotate Dehydrogenase Inhibitor Series. Journal of medicinal chemistry 2021. PMID: 33876936
Rani A, Sharma A, Legac J, Rosenthal PJ, Singh P, Kumar V. A trio of quinoline-isoniazid-phthalimide with promising antiplasmodial potential: Synthesis, in-vitro evaluation and heme-polymerization inhibition studies. Bioorganic & medicinal chemistry 2021. PMID: 33895706
Rosenthal PJ. Has artemisinin resistance emerged in Africa? The Lancet. Infectious diseases 2021. PMID: 33864802
Asua V, Conrad MD, Aydemir O, Duvalsaint M, Legac J, Duarte E, Tumwebaze P, Chin DM, Cooper RA, Yeka A, Kamya MR, Dorsey G, Nsobya SL, Bailey J, Rosenthal PJ. Changing Prevalence of Potential Mediators of Aminoquinoline, Antifolate, and Artemisinin Resistance Across Uganda. The Journal of infectious diseases 2021. PMID: 33146722
Shavelle RM, Kwak JH, Saur R, Brooks JC, Rosenthal P. Life Expectancy after Liver Transplantation for Non-Cirrhotic Hepatocellular Carcinoma. 2021. PMID: 33722096
Zhan W, Zhang H, Ginn J, Leung A, Liu YJ, Michino M, Toita A, Okamoto R, Wong TT, Imaeda T, Hara R, Yukawa T, Chelebieva S, Tumwebaze PK, Lafuente-Monasterio MJ, Martinez-Martinez MS, Vendome J, Beuming T, Sato K, Aso K, Rosenthal PJ, Cooper RA, Meinke PT, Nathan CF, Kirkman LA, Lin G. Development of a Highly Selective Plasmodium falciparum Proteasome Inhibitor with Anti-malaria Activity in Humanized Mice. Angewandte Chemie (International ed. in English) 2021. PMID: 33433953
Tukwasibwe S, Traherne JA, Chazara O, Jayaraman J, Trowsdale J, Moffett A, Jiang W, Nankabirwa JI, Rek J, Arinaitwe E, Nsobya SL, Atuheirwe M, Frank M, Godwin A, Jagannathan P, Cose S, Kamya MR, Dorsey G, Rosenthal PJ, Colucci F, Nakimuli A. Diversity of KIR genes and their HLA-C ligands in Ugandan populations with historically varied malaria transmission intensity. Malaria journal 2021. PMID: 33632228
Briggs J, Kuchta A, Murphy M, Tessema S, Arinaitwe E, Rek J, Chen A, Nankabirwa JI, Drakeley C, Smith D, Bousema T, Kamya M, Rodriguez-Barraquer I, Staedke S, Dorsey G, Rosenthal PJ, Greenhouse B. Within-household clustering of genetically related Plasmodium falciparum infections in a moderate transmission area of Uganda. Malaria journal 2021. PMID: 33531029
Ssewanyana I, Rek J, Rodriguez I, Wu L, Arinaitwe E, Nankabirwa JI, Beeson JG, Mayanja-Kizza H, Rosenthal PJ, Dorsey G, Kamya MR, Drakeley C, Greenhouse B, Tetteh KKA. Impact of a Rapid Decline in Malaria Transmission on Antimalarial IgG Subclasses and Avidity. Frontiers in immunology 2021. PMID: 33584643
Mwesigwa M, Webster JL, Nsobya SL, Rowan A, Basnet MS, Phares CR, Weinberg M, Klosovsky A, Naoum M, Rosenthal PJ, Stauffer W. Prevalence of Malaria Parasite Infections among U.S.-Bound Congolese Refugees with and without Splenomegaly. 2021. PMID: 33534754
Nsobya SL, Walakira A, Namirembe E, Kiggundu M, Nankabirwa JI, Ruhamyankaka E, Arinaitwe E, Conrad MD, Kamya MR, Dorsey G, Rosenthal PJ. Deletions of pfhrp2 and pfhrp3 genes were uncommon in rapid diagnostic test-negative Plasmodium falciparum isolates from Uganda. Malaria journal 2021. PMID: 33386076
Rosenthal PJ. Year 100 of the American Journal of Tropical Medicine and Hygiene: A Remarkable Year. The American journal of tropical medicine and hygiene 2021. PMID: 33432913
Rek J, Musiime A, Zedi M, Otto G, Kyagamba P, Asiimwe Rwatooro J, Arinaitwe E, Nankabirwa J, Staedke SG, Drakeley C, Rosenthal PJ, Kamya M, Dorsey G, Krezanoski PJ. Non-adherence to long-lasting insecticide treated bednet use following successful malaria control in Tororo, Uganda. PloS one 2020. PMID: 33270743
Newton KP, Lavine JE, Wilson L, Behling C, Vos MB, Molleston JP, Rosenthal P, Miloh T, Fishbein MH, Jain AK, Murray KF, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Alanine Aminotransferase and Gamma-Glutamyl Transpeptidase Predict Histologic Improvement in Pediatric Nonalcoholic Steatohepatitis. Hepatology (Baltimore, Md.) 2020. PMID: 32416645
Nayebare P, Asua V, Conrad MD, Kajubi R, Kakuru A, Nankabirwa JI, Muhanguzi D, Dorsey G, Kamya MR, Nsobya S, Rosenthal PJ. Associations between Malaria-Preventive Regimens and Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Ugandan Pregnant Women. Antimicrobial agents and chemotherapy 2020. PMID: 33020152
Hughes E, Imperial M, Wallender E, Kajubi R, Huang L, Jagannathan P, Zhang N, Kakuru A, Natureeba P, Mwima MW, Muhindo M, Mwebaza N, Clark TD, Opira B, Nakalembe M, Havlir D, Kamya M, Rosenthal PJ, Dorsey G, Aweeka F, Savic RM. Piperaquine Exposure Is Altered by Pregnancy, HIV, and Nutritional Status in Ugandan Women. Antimicrobial agents and chemotherapy 2020. PMID: 33020153
Arinaitwe E, Nankabirwa JI, Krezanoski P, Rek J, Kamya V, Epstein A, Rosenthal PJ, Drakeley C, Kamya MR, Dorsey G, Staedke SG. Association between recent overnight travel and use of long-lasting insecticidal nets in rural Uganda: a prospective cohort study in Tororo. Malaria journal 2020. PMID: 33176793
Butler JH, Baptista RP, Valenciano AL, Zhou B, Kissinger JC, Tumwebaze PK, Rosenthal PJ, Cooper RA, Yue JM, Cassera MB. Resistance to Some But Not Other Dimeric Lindenane Sesquiterpenoid Esters Is Mediated by Mutations in a Plasmodium falciparum Esterase. ACS infectious diseases 2020. PMID: 32970404
Venkat V, Ng VL, Magee JC, Ye W, Hawthorne K, Harpavat S, Molleston JP, Murray KF, Wang KS, Soufi N, Bass LM, Alonso EM, Bezerra JA, Jensen MK, Kamath BM, Loomes KM, Mack CL, Rosenthal P, Shneider BL, Squires RH, Sokol RJ, Karpen SJ, Childhood Liver Disease Research Network. Modeling Outcomes in Children With Biliary Atresia With Native Liver After 2 Years of Age. Hepatology communications 2020. PMID: 33305153
Arinaitwe E, Mpimbaza A, Nankabirwa JI, Kamya V, Asiimwe A, Kuule JK, Kamya MR, Drakeley C, Dorsey G, Rosenthal PJ, Staedke SG. Malaria Diagnosed in an Urban Setting Strongly Associated with Recent Overnight Travel: A Case-Control Study from Kampala, Uganda. The American journal of tropical medicine and hygiene 2020. PMID: 32840203
Cuu G, Asua V, Tukwasibwe S, Nsobya SL, Nanteza A, Kimuda MP, Mpimbaza A, Rosenthal PJ. Associations between Aminoquinoline Resistance Genotypes and Clinical Presentations of Plasmodium falciparum Infection in Uganda. Antimicrobial agents and chemotherapy 2020. PMID: 32660999
Rosenthal PJ, Bausch DG, Goraleski KA, Hill DR, Jacobson JA, John CC, Breman JG. Keep Politics out of Funding Decisions for Medical Research and Public Health. The American journal of tropical medicine and hygiene 2020. PMID: 32700678
Shneider BL, Goodrich NP, Ye W, Sawyers C, Molleston JP, Merion RM, Leung DH, Karpen SJ, Kamath BM, Cavallo L, Wang K, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Murray KF, Loomes KM, Jensen MK, Bezerra JA, Bass LM, Sokol RJ, Magee JC, Childhood Liver Disease Research Network (ChiLDReN). Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease. Hepatology communications 2020. PMID: 33163838
Xanthakos SA, Lavine JE, Yates KP, Schwimmer JB, Molleston JP, Rosenthal P, Murray KF, Vos MB, Jain AK, Scheimann AO, Miloh T, Fishbein M, Behling CA, Brunt EM, Sanyal AJ, Tonascia J, NASH Clinical Research Network. Progression of Fatty Liver Disease in Children Receiving Standard of Care Lifestyle Advice. Gastroenterology 2020. PMID: 32712103
Teckman J, Rosenthal P, Hawthorne K, Spino C, Bass LM, Murray KF, Kerkar N, Magee JC, Karpen S, Heubi JE, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Sherker AH, Sokol RJ, ChiLDReN (Childhood Liver Disease Research Network). Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension. The Journal of pediatrics 2020. PMID: 32663593
Rodriguez-Baez N, Murray KF, Kleiner DE, Ling SC, Rosenthal P, Carlin K, Cooper K, Schwarz KB, Schwarzenberg SJ, Teckman JH, Ghany MG, Alawad AS. Hepatic Histology in Treatment-naïve Children With Chronic Hepatitis B Infection Living in the United States and Canada. Journal of pediatric gastroenterology and nutrition 2020. PMID: 32265408
Kumar S, Saini A, Legac J, Rosenthal PJ, Raj R, Kumar V. Amalgamating Isatin/Indole/Nitroimidazole with 7-chloroquinolines via azide-alkyne cycloaddition: Synthesis, anti-plasmodial, and cytotoxic evaluation. Chemical biology & drug design 2020. PMID: 32515142
Tukwasibwe S, Nakimuli A, Traherne J, Chazara O, Jayaraman J, Trowsdale J, Moffett A, Jagannathan P, Rosenthal PJ, Cose S, Colucci F. Variations in killer-cell immunoglobulin-like receptor and human leukocyte antigen genes and immunity to malaria. Cellular & molecular immunology 2020. PMID: 32541835
Andrus JK, Evans-Gilbert T, Santos JI, Guzman MG, Rosenthal PJ, Toscano C, Valenzuela MT, Siqueira M, Etienne C, Breman JG. Perspectives on Battling COVID-19 in Countries of Latin America and the Caribbean. The American journal of tropical medicine and hygiene 2020. PMID: 32524963
Rosenthal PJ, Breman JG, Djimde AA, John CC, Kamya MR, Leke RGF, Moeti MR, Nkengasong J, Bausch DG. COVID-19: Shining the Light on Africa. The American journal of tropical medicine and hygiene 2020. PMID: 32372749
Mwebaza N, Cheah V, Forsman C, Kajubi R, Marzan F, Wallender E, Dorsey G, Rosenthal PJ, Aweeka F, Huang L. Determination of piperaquine concentration in human plasma and the correlation of capillary versus venous plasma concentrations. PloS one 2020. PMID: 32470030
Kancharla P, Dodean RA, Li Y, Pou S, Pybus B, Melendez V, Read L, Bane CE, Vesely B, Kreishman-Deitrick M, Black C, Li Q, Sciotti RJ, Olmeda R, Luong TL, Gaona H, Potter B, Sousa J, Marcsisin S, Caridha D, Xie L, Vuong C, Zeng Q, Zhang J, Zhang P, Lin H, Butler K, Roncal N, Gaynor-Ohnstad L, Leed SE, Nolan C, Ceja FG, Rasmussen SA, Tumwebaze PK, Rosenthal PJ, Mu J, Bayles BR, Cooper RA, Reynolds KA, Smilkstein MJ, Riscoe MK, Kelly JX. Lead Optimization of Second-Generation Acridones as Broad-Spectrum Antimalarials. Journal of medicinal chemistry 2020. PMID: 32390431
Kamath BM, Spino C, McLain R, Magee JC, Fredericks EM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Alonso EM, Murray KF, Loomes KM, Kyle Jensen M, Karpen SJ, Rosenthal P, Thomas D, Sokol RJ, Shneider BL, Childhood Liver Disease Research Network (ChiLDReN). Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With Alagille Syndrome. Hepatology communications 2020. PMID: 32626833
Rosenthal P, Narkewicz MR, Yao BB, Jolley CD, Lobritto SJ, Wen J, Molleston JP, Hsu EK, Jonas MM, Zha J, Liu L, Leung DH. Ombitasvir, Paritaprevir, Ritonavir, and Dasabuvir Mini-Tabs Plus Ribavirin for Children Aged 3-11 Years with Hepatitis C Genotype 1a. Advances in therapy 2020. PMID: 32451952
Blank BR, Gonciarz RL, Talukder P, Gut J, Legac J, Rosenthal PJ, Renslo AR. Antimalarial Trioxolanes with Superior Drug-Like Properties and In Vivo Efficacy. ACS infectious diseases 2020. PMID: 32369341
Kamya MR, Kakuru A, Muhindo M, Arinaitwe E, Nankabirwa JI, Rek J, Bigira V, Kapisi J, Wanzira H, Achan J, Natureeba P, Gasasira A, Havlir D, Jagannathan P, Rosenthal PJ, Rodriguez-Barraquer I, Dorsey G. The Impact of Control Interventions on Malaria Burden in Young Children in a Historically High-Transmission District of Uganda: A Pooled Analysis of Cohort Studies from 2007 to 2018. The American journal of tropical medicine and hygiene 2020. PMID: 32431280
Rosenthal PJ. The Importance of Diagnostic Testing during a Viral Pandemic: Early Lessons from Novel Coronavirus Disease (COVID-19). The American journal of tropical medicine and hygiene 2020. PMID: 32238224
Verity R, Aydemir O, Brazeau NF, Watson OJ, Hathaway NJ, Mwandagalirwa MK, Marsh PW, Thwai K, Fulton T, Denton M, Morgan AP, Parr JB, Tumwebaze PK, Conrad M, Rosenthal PJ, Ishengoma DS, Ngondi J, Gutman J, Mulenga M, Norris DE, Moss WJ, Mensah BA, Myers-Hansen JL, Ghansah A, Tshefu AK, Ghani AC, Meshnick SR, Bailey JA, Juliano JJ. The impact of antimalarial resistance on the genetic structure of Plasmodium falciparum in the DRC. Nature communications 2020. PMID: 32355199
Rosenthal PJ. Are three drugs for malaria better than two? Lancet (London, England) 2020. PMID: 32171077
Taylor SA, Venkat V, Arnon R, Gopalareddy VV, Rosenthal P, Erinjeri J, Anand R, Daniel JF, Society of Pediatric Liver Transplantation. Improved Outcomes for Liver Transplantation in Patients with Biliary Atresia Since Pediatric End-Stage Liver Disease Implementation: Analysis of the Society of Pediatric Liver Transplantation Registry. The Journal of pediatrics 2020. PMID: 32005543
Sindhe KMV, Wu W, Legac J, Zhang YK, Easom EE, Cooper RA, Plattner JJ, Freund YR, DeRisi JL, Rosenthal PJ. Plasmodium falciparum Resistance to a Lead Benzoxaborole Due to Blocked Compound Activation and Altered Ubiquitination or Sumoylation. mBio 2020. PMID: 31992618
Kamath BM, Ye W, Goodrich NP, Loomes KM, Romero R, Heubi JE, Leung DH, Spinner NB, Piccoli DA, Alonso EM, Guthery SL, Karpen SJ, Mack CL, Molleston JP, Murray KF, Rosenthal P, Squires JE, Teckman J, Wang KS, Thompson R, Magee JC, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study. Hepatology communications 2020. PMID: 33313463
Kakande E, Greenhouse B, Bajunirwe F, Drakeley C, Nankabirwa JI, Walakira A, Nsobya SL, Katureebe A, Rek J, Arinaitwe E, Rosenthal PJ, Kamya MR, Dorsey G, Rodriguez-Barraquer I. Associations between red blood cell variants and malaria among children and adults from three areas of Uganda: a prospective cohort study. Malaria journal 2020. PMID: 31941490
Rosenthal PJ. Falcipain cysteine proteases of malaria parasites: An update. Biochimica et biophysica acta. Proteins and proteomics 2020. PMID: 31927030
Legac J, Adeniyi AA, Kisten P, Rosenthal PJ, Singh P, Kumar V. Functionalized Naphthalimide-4-aminoquinoline Conjugates as Promising Antiplasmodials, with Mechanistic Insights. ACS medicinal chemistry letters 2020. PMID: 32071682
Squires JE, Ng VL, Hawthorne K, Henn LL, Sorensen LG, Fredericks EM, Alonso EM, Murray KF, Loomes KM, Karpen SJ, Cavallo LA, Molleston JP, Bezerra JA, Rosenthal P, Squires RH, Wang KS, Schwarz KB, Arnon R, Magee JC, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Neurodevelopmental Outcomes in Preschool and School Aged Children With Biliary Atresia and Their Native Liver. Journal of pediatric gastroenterology and nutrition 2020. PMID: 31503218
Aguiar L, Biosca A, Lantero E, Gut J, Vale N, Rosenthal PJ, Nogueira F, Andreu D, Fernàndez-Busquets X, Gomes P. Coupling the Antimalarial Cell Penetrating Peptide TP10 to Classical Antimalarial Drugs Primaquine and Chloroquine Produces Strongly Hemolytic Conjugates. Molecules (Basel, Switzerland) 2019. PMID: 31842498
Rani A, Kumar S, Legac J, Adeniyi AA, Awolade P, Singh P, Rosenthal PJ, Kumar V. Design, synthesis, heme binding and density functional theory studies of isoindoline-dione-4-aminoquinolines as potential antiplasmodials. Future medicinal chemistry 2019. PMID: 31802710
Oldenburg CE, Amza A, Cooley G, Kadri B, Nassirou B, Arnold BF, Rosenthal PJ, O'Brien KS, West SK, Bailey RL, Porco TC, Keenan JD, Lietman TM, Martin DL. Biannual versus annual mass azithromycin distribution and malaria seroepidemiology among preschool children in Niger: a sub-study of a cluster randomized trial. Malaria journal 2019. PMID: 31796025
Kortz TB, Nyirenda J, Tembo D, Elfving K, Baltzell K, Bandawe G, Rosenthal PJ, Macfarlane SB, Mandala W, Nyirenda TS. Distinct Biomarker Profiles Distinguish Malawian Children with Malarial and Non-malarial Sepsis. The American journal of tropical medicine and hygiene 2019. PMID: 31595873
Tilley L, Rosenthal PJ. Malaria parasites fine-tune mutations to resist drugs. Nature 2019. PMID: 31822828
Sharma B, Kaur S, Legac J, Rosenthal PJ, Kumar V. Synthesis, anti-plasmodial and cytotoxic evaluation of 1H-1,2,3-triazole/acyl hydrazide integrated tetrahydro-β-carboline-4-aminoquinoline conjugates. Bioorganic & medicinal chemistry letters 2019. PMID: 31740250
Rosenthal PJ. Be Careful What You Eat! The American journal of tropical medicine and hygiene 2019. PMID: 31549613
Schwarz KB, Lombardero M, Di Bisceglie AM, Murray KF, Rosenthal P, Ling SC, Cloonan YK, Rodriguez-Baez N, Schwarzenberg SJ, Hoofnagle JH, Teckman J, Hepatitis B Research Network (HBRN). Phenotypes of Chronic Hepatitis B in Children From a Large North American Cohort. Journal of pediatric gastroenterology and nutrition 2019. PMID: 31436702
de J Parra Y, Andueza L FD, Ferrer M RE, Bruno Colmenarez J, Acosta ME, Charris J, Rosenthal PJ, Gut J. [(7-chloroquinolin-4-yl)amino]acetophenones and their copper(II) derivatives: Synthesis, characterization, computational studies and antimalarial activity. EXCLI journal 2019. PMID: 31762723
Conrad MD, Nsobya SL, Rosenthal PJ. The Diversity of the Plasmodium falciparum K13 Propeller Domain Did Not Increase after Implementation of Artemisinin-Based Combination Therapy in Uganda. Antimicrobial agents and chemotherapy 2019. PMID: 31358588
Rosenthal PJ. Artemisinin Resistance in Eastern India. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019. PMID: 30541018
Danial E, Fleck-Derderian S, Rosenthal P. Has Rotavirus Vaccination Decreased the Prevalence of Biliary Atresia? Journal of clinical gastroenterology 2019. PMID: 30222646
Black DD, Mack C, Kerkar N, Miloh T, Sundaram SS, Anand R, Gupta A, Alonso E, Arnon R, Bulut P, Karpen S, Lin CH, Rosenthal P, Ryan M, Squires RH, Valentino P, Elsea SH, Shneider BL. A Prospective Trial of Withdrawal and Reinstitution of Ursodeoxycholic Acid in Pediatric Primary Sclerosing Cholangitis. Hepatology communications 2019. PMID: 31701072
Schwarz KB, Rosenthal P, Murray KF, Honegger JR, Hardikar W, Hague R, Mittal N, Massetto B, Brainard DM, Hsueh CH, Shao J, Parhy B, Narkewicz MR, Rao GS, Whitworth S, Bansal S, Balistreri WF. Ledipasvir-Sofosbuvir for 12 Weeks in Children 3 to <6 Years Old With Chronic Hepatitis C. Hepatology (Baltimore, Md.) 2019. PMID: 31220349
Rosenthal P, Schwarz KB, Gonzalez-Peralta RP, Lin CH, Kelly DA, Nightingale S, Balistreri WF, Bansal S, Jonas MM, Massetto B, Brainard DM, Hsueh CH, Shao J, Parhy B, Davison S, Feiterna-Sperling C, Gillis LA, Indolfi G, Sokal EM, Murray KF, Wirth S. Sofosbuvir and Ribavirin Therapy for Children Aged 3 to <12 Years With Hepatitis C Virus Genotype 2 or 3 Infection. Hepatology (Baltimore, Md.) 2019. PMID: 31222783
Conrad MD, Rosenthal PJ. Antimalarial drug resistance in Africa: the calm before the storm? The Lancet. Infectious diseases 2019. PMID: 31375467
Whalen ME, Kajubi R, Chamankhah N, Huang L, Orukan F, Wallender E, Kamya MR, Dorsey G, Jagannathan P, Rosenthal PJ, Mwebaza N, Aweeka FT. Reduced Exposure to Piperaquine, Compared to Adults, in Young Children Receiving Dihydroartemisinin-Piperaquine as Malaria Chemoprevention. Clinical pharmacology and therapeutics 2019. PMID: 31173649
Rosenthal PJ. A shorter course for anti-relapse therapy against vivax malaria. Lancet (London, England) 2019. PMID: 31327565
Guler JL, Rosenthal PJ. Mass Drug Administration to Control and Eliminate Malaria in Africa: How Do We Best Utilize the Tools at Hand? Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019. PMID: 30304408
Lunde CS, Stebbins EE, Jumani RS, Hasan MM, Miller P, Barlow J, Freund YR, Berry P, Stefanakis R, Gut J, Rosenthal PJ, Love MS, McNamara CW, Easom E, Plattner JJ, Jacobs RT, Huston CD. Identification of a potent benzoxaborole drug candidate for treating cryptosporidiosis. Nature communications 2019. PMID: 31249291
Arzika AM, Maliki R, Boubacar N, Kane S, Cotter SY, Lebas E, Cook C, Bailey RL, West SK, Rosenthal PJ, Porco TC, Lietman TM, Keenan JD, MORDOR Study Group. Biannual mass azithromycin distributions and malaria parasitemia in pre-school children in Niger: A cluster-randomized, placebo-controlled trial. PLoS medicine 2019. PMID: 31237871
Zhan W, Visone J, Ouellette T, Harris JC, Wang R, Zhang H, Singh PK, Ginn J, Sukenick G, Wong TT, Okoro JI, Scales RM, Tumwebaze PK, Rosenthal PJ, Kafsack BFC, Cooper RA, Meinke PT, Kirkman LA, Lin G. Improvement of Asparagine Ethylenediamines as Anti-malarial Plasmodium-Selective Proteasome Inhibitors. Journal of medicinal chemistry 2019. PMID: 31177777
Ramesh A, Nakielny S, Hsu J, Kyohere M, Byaruhanga O, de Bourcy C, Egger R, Dimitrov B, Juan YF, Sheu J, Wang J, Kalantar K, Langelier C, Ruel T, Mpimbaza A, Wilson MR, Rosenthal PJ, DeRisi JL. Metagenomic next-generation sequencing of samples from pediatric febrile illness in Tororo, Uganda. PloS one 2019. PMID: 31220115
Mpimbaza A, Nayiga S, Ndeezi G, Rosenthal PJ, Karamagi C, Katahoire A. Understanding the context of delays in seeking appropriate care for children with symptoms of severe malaria in Uganda. PloS one 2019. PMID: 31166968
Rosenthal PJ, Tan KR. Expanded Availability of Intravenous Artesunate for the Treatment of Severe Malaria in the United States. The American journal of tropical medicine and hygiene 2019. PMID: 30927931
Stoye A, Juillard A, Tang AH, Legac J, Gut J, White KL, Charman SA, Rosenthal PJ, Grau GER, Hunt NH, Payne RJ. Falcipain Inhibitors Based on the Natural Product Gallinamide A Are Potent in Vitro and in Vivo Antimalarials. Journal of medicinal chemistry 2019. PMID: 31062592
Di Bisceglie AM, King WC, Lisker-Melman M, Khalili M, Belle SH, Feld JJ, Ghany MG, Janssen HLA, Lau D, Lee WM, Ling SC, Cooper S, Rosenthal P, Schwarz KB, Sterling RK, Teckman JH, Terrault N, Hepatitis B Research Network (HBRN). Age, race and viral genotype are associated with the prevalence of hepatitis B e antigen in children and adults with chronic hepatitis B. Journal of viral hepatitis 2019. PMID: 30974509
Rani A, Legac J, Rosenthal PJ, Kumar V. Substituted 1,3-dioxoisoindoline-4-aminoquinolines coupled via amide linkers: Synthesis, antiplasmodial and cytotoxic evaluation. Bioorganic chemistry 2019. PMID: 30991190
Berauer JP, Mezina AI, Okou DT, Sabo A, Muzny DM, Gibbs RA, Hegde MR, Chopra P, Cutler DJ, Perlmutter DH, Bull LN, Thompson RJ, Loomes KM, Spinner NB, Rajagopalan R, Guthery SL, Moore B, Yandell M, Harpavat S, Magee JC, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Alonso EM, Rosenthal P, Squires RH, Wang KS, Finegold MJ, Russo P, Sherker AH, Sokol RJ, Karpen SJ, Childhood Liver Disease Research Network (ChiLDReN). Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome. Hepatology (Baltimore, Md.) 2019. PMID: 30664273
Yeka A, Wallender E, Mulebeke R, Kibuuka A, Kigozi R, Bosco A, Kyambadde P, Opigo J, Kalyesubula S, Senzoga J, Vinden J, Conrad M, Rosenthal PJ. Comparative Efficacy of Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine for the Treatment of Uncomplicated Malaria in Ugandan Children. The Journal of infectious diseases 2019. PMID: 30418593
Nankabirwa JI, Briggs J, Rek J, Arinaitwe E, Nayebare P, Katrak S, Staedke SG, Rosenthal PJ, Rodriguez-Barraquer I, Kamya MR, Dorsey G, Greenhouse B. Persistent Parasitemia Despite Dramatic Reduction in Malaria Incidence After 3 Rounds of Indoor Residual Spraying in Tororo, Uganda. The Journal of infectious diseases 2019. PMID: 30383230
Asua V, Vinden J, Conrad MD, Legac J, Kigozi SP, Kamya MR, Dorsey G, Nsobya SL, Rosenthal PJ. Changing Molecular Markers of Antimalarial Drug Sensitivity across Uganda. Antimicrobial agents and chemotherapy 2019. PMID: 30559133
Rosenthal P, Ling SC, Belle SH, Murray KF, Rodriguez-Baez N, Schwarzenberg SJ, Teckman J, Lin HS, Schwarz KB, Hepatitis B Research Network (HBRN). Combination of Entecavir/Peginterferon Alfa-2a in Children With Hepatitis B e Antigen-Positive Immune Tolerant Chronic Hepatitis B Virus Infection. Hepatology (Baltimore, Md.) 2019. PMID: 30318613
Rosenthal PJ, John CC, Rabinovich NR. Malaria: How Are We Doing and How Can We Do Better? The American journal of tropical medicine and hygiene 2019. PMID: 30628572
Wallender E, Zhang N, Conrad M, Kakuru A, Muhindo M, Tumwebaze P, Kajubi R, Mota D, Legac J, Jagannathan P, Havlir D, Kamya M, Dorsey G, Aweeka F, Rosenthal PJ, Savic RM. Modeling Prevention of Malaria and Selection of Drug Resistance with Different Dosing Schedules of Dihydroartemisinin-Piperaquine Preventive Therapy during Pregnancy in Uganda. Antimicrobial agents and chemotherapy 2019. PMID: 30530597
Chotsiri P, Zongo I, Milligan P, Compaore YD, Somé AF, Chandramohan D, Hanpithakpong W, Nosten F, Greenwood B, Rosenthal PJ, White NJ, Ouédraogo JB, Tarning J. Optimal dosing of dihydroartemisinin-piperaquine for seasonal malaria chemoprevention in young children. Nature communications 2019. PMID: 30696903
Hilk K, Zerofsky M, Rhee S, Rosenthal P, Perito ER. Center variation in screening for and management of metabolic syndrome in pediatric liver transplant recipients: A survey of SPLIT centers. Pediatric transplantation 2019. PMID: 30664821
Arinaitwe E, Dorsey G, Nankabirwa JI, Kigozi SP, Katureebe A, Kakande E, Rek J, Rosenthal PJ, Drakeley C, Kamya MR, Staedke SG. Association Between Recent Overnight Travel and Risk of Malaria: A Prospective Cohort Study at 3 Sites in Uganda. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2019. PMID: 29868722
Chambers JH, Zerofsky M, Lustig RH, Rosenthal P, Perito ER. Diet and Exercise in Pediatric Liver Transplant Recipients: Behaviors and Association With Metabolic Syndrome. Journal of pediatric gastroenterology and nutrition 2019. PMID: 30234760
Rosenthal PJ, Vinetz JM, Siegel C, Kazura JW. Volume 100 of the American Journal of Tropical Medicine and Hygiene. The American journal of tropical medicine and hygiene 2019. PMID: 30652665
Loomes KM, Spino C, Goodrich NP, Hangartner TN, Marker AE, Heubi JE, Kamath BM, Shneider BL, Rosenthal P, Hertel PM, Karpen SJ, Molleston JP, Murray KF, Schwarz KB, Squires RH, Teckman J, Turmelle YP, Alonso EM, Sherker AH, Magee JC, Sokol RJ, Childhood Liver Disease Research Network. Bone Density in Children With Chronic Liver Disease Correlates With Growth and Cholestasis. Hepatology (Baltimore, Md.) 2018. PMID: 30063078
Mpimbaza A, Katahoire A, Rosenthal PJ, Karamagi C, Ndeezi G. Caregiver responses and association with delayed care-seeking in children with uncomplicated and severe malaria. Malaria journal 2018. PMID: 30563514
Rosenthal PJ. Artemisinin Resistance Outside of Southeast Asia. The American journal of tropical medicine and hygiene 2018. PMID: 30426924
Murray KF, Balistreri WF, Bansal S, Whitworth S, Evans HM, Gonzalez-Peralta RP, Wen J, Massetto B, Kersey K, Shao J, Garrison KL, Parhy B, Brainard DM, Arnon R, Gillis LA, Jonas MM, Lin CH, Narkewicz MR, Schwarz K, Rosenthal P. Safety and Efficacy of Ledipasvir-Sofosbuvir With or Without Ribavirin for Chronic Hepatitis C in Children Ages 6-11. Hepatology (Baltimore, Md.) 2018. PMID: 30070726
Rosenthal P. Advances in Pediatric Hepatology. Clinics in liver disease 2018. PMID: 30266164
Leung DH, Wirth S, Yao BB, Viani RM, Gonzalez-Peralta RP, Jonas MM, Lobritto SJ, Narkewicz MR, Sokal E, Fortuny C, Hsu EK, Del Valle-Segarra A, Zha J, Larsen L, Liu L, Shuster DL, Cohen DE, Rosenthal P. Ombitasvir/Paritaprevir/Ritonavir With or Without Dasabuvir and With or Without Ribavirin for Adolescents With HCV Genotype 1 or 4. Hepatology communications 2018. PMID: 30411078
Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL, Thomas D, Sherker AH, Sokol RJ, Childhood Liver Disease Research Network. Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome. Hepatology communications 2018. PMID: 30288474
Alonso EM, Ye W, Hawthorne K, Venkat V, Loomes KM, Mack CL, Hertel PM, Karpen SJ, Kerkar N, Molleston JP, Murray KF, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Suchy FJ, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Bezerra JA, Magee JC, ChiLDReN Network. Impact of Steroid Therapy on Early Growth in Infants with Biliary Atresia: The Multicenter Steroids in Biliary Atresia Randomized Trial. The Journal of pediatrics 2018. PMID: 30244988
Nsanzabana C, Ariey F, Beck HP, Ding XC, Kamau E, Krishna S, Legrand E, Lucchi N, Miotto O, Nag S, Noedl H, Roper C, Rosenthal PJ, Schallig HDFH, Taylor SM, Volkman SK, Gonzalez IJ. Molecular assays for antimalarial drug resistance surveillance: A target product profile. PloS one 2018. PMID: 30235327
Mpimbaza A, Walakira A, Ndeezi G, Katahoire A, Karamagi C, Nsobya SL, Tukwasibwe S, Asua V, Rosenthal PJ. Associations between erythrocyte polymorphisms and risks of uncomplicated and severe malaria in Ugandan children: A case control study. PloS one 2018. PMID: 30222732
Savic RM, Jagannathan P, Kajubi R, Huang L, Zhang N, Were M, Kakuru A, Muhindo MK, Mwebaza N, Wallender E, Clark TD, Opira B, Kamya M, Havlir DV, Rosenthal PJ, Dorsey G, Aweeka FT. Intermittent Preventive Treatment for Malaria in Pregnancy: Optimization of Target Concentrations of Dihydroartemisinin-Piperaquine. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2018. PMID: 29547881
Siqueira-Neto JL, Debnath A, McCall LI, Bernatchez JA, Ndao M, Reed SL, Rosenthal PJ. Cysteine proteases in protozoan parasites. PLoS neglected tropical diseases 2018. PMID: 30138453
Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance. Proceedings of the National Academy of Sciences of the United States of America 2018. PMID: 29967165
Siddiqui FA, Cabrera M, Wang M, Brashear A, Kemirembe K, Wang Z, Miao J, Chookajorn T, Yang Z, Cao Y, Dong G, Rosenthal PJ, Cui L. Plasmodium falciparum Falcipain-2a Polymorphisms in Southeast Asia and Their Association With Artemisinin Resistance. The Journal of infectious diseases 2018. PMID: 29659945
Kortz T, Rosenthal PJ. Reconciling Conflicting Results From Pediatric Sepsis Studies: The Need for Context-Specific Sepsis Bundles. Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies 2018. PMID: 29863649
Schaub JR, Huppert KA, Kurial SNT, Hsu BY, Cast AE, Donnelly B, Karns RA, Chen F, Rezvani M, Luu HY, Mattis AN, Rougemont AL, Rosenthal P, Huppert SS, Willenbring H. De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation. Nature 2018. PMID: 29720662
Narkewicz MR, Horslen S, Hardison RM, Shneider BL, Rodriguez-Baez N, Alonso EM, Ng VL, Leonis MA, Loomes KM, Rudnick DA, Rosenthal P, Romero R, Subbarao GC, Li R, Belle SH, Squires RH, Pediatric Acute Liver Failure Study Group. A Learning Collaborative Approach Increases Specificity of Diagnosis of Acute Liver Failure in Pediatric Patients. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2018. PMID: 29723692
Harlow KE, Africa JA, Wells A, Belt PH, Behling CA, Jain AK, Molleston JP, Newton KP, Rosenthal P, Vos MB, Xanthakos SA, Lavine JE, Schwimmer JB, Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN). Clinically Actionable Hypercholesterolemia and Hypertriglyceridemia in Children with Nonalcoholic Fatty Liver Disease. The Journal of pediatrics 2018. PMID: 29661561
Bull LN, Pawlikowska L, Strautnieks S, Jankowska I, Czubkowski P, Dodge JL, Emerick K, Wanty C, Wali S, Blanchard S, Lacaille F, Byrne JA, van Eerde AM, Kolho KL, Houwen R, Lobritto S, Hupertz V, McClean P, Mieli-Vergani G, Sokal E, Rosenthal P, Whitington PF, Pawlowska J, Thompson RJ. Outcomes of surgical management of familial intrahepatic cholestasis 1 and bile salt export protein deficiencies. Hepatology communications 2018. PMID: 29761168
Publicover J, Gaggar A, Jespersen JM, Halac U, Johnson AJ, Goodsell A, Avanesyan L, Nishimura SL, Holdorf M, Mansfield KG, Judge JB, Koshti A, Croft M, Wakil AE, Rosenthal P, Pai E, Cooper S, Baron JL. An OX40/OX40L interaction directs successful immunity to hepatitis B virus. Science translational medicine 2018. PMID: 29563320
Ng VL, Sorensen LG, Alonso EM, Fredericks EM, Ye W, Moore J, Karpen SJ, Shneider BL, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Rosenthal P, Squires RH, Wang K, Arnon R, Schwarz KB, Turmelle YP, Haber BH, Sherker AH, Magee JC, Sokol RJ, Childhood Liver Disease Research Network (ChiLDReN). Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study. The Journal of pediatrics 2018. PMID: 29519540
Wallender E, Vucicevic K, Jagannathan P, Huang L, Natureeba P, Kakuru A, Muhindo M, Nakalembe M, Havlir D, Kamya M, Aweeka F, Dorsey G, Rosenthal PJ, Savic RM. Predicting Optimal Dihydroartemisinin-Piperaquine Regimens to Prevent Malaria During Pregnancy for Human Immunodeficiency Virus-Infected Women Receiving Efavirenz. The Journal of infectious diseases 2018. PMID: 29272443
Capela R, Magalhães J, Miranda D, Machado M, Sanches-Vaz M, Albuquerque IS, Sharma M, Gut J, Rosenthal PJ, Frade R, Perry MJ, Moreira R, Prudêncio M, Lopes F. Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability. European journal of medicinal chemistry 2018. PMID: 29499488
Katrak S, Nayebare P, Rek J, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B. Clinical consequences of submicroscopic malaria parasitaemia in Uganda. Malaria journal 2018. PMID: 29402282
Verstraete SG, Wojcicki JM, Perito ER, Rosenthal P. Bisphenol a increases risk for presumed non-alcoholic fatty liver disease in Hispanic adolescents in NHANES 2003-2010. Environmental health : a global access science source 2018. PMID: 29391015
Younossi ZM, Stepanova M, Balistreri W, Schwarz K, Murray KF, Rosenthal P, Bansal S, Hunt S. Health-related Quality of Life in Adolescent Patients With Hepatitis C Genotype 1 Treated With Sofosbuvir and Ledipasvir. Journal of pediatric gastroenterology and nutrition 2018. PMID: 28957984
Perito ER, Phelps A, Vase T, Feldstein VA, Lustig RH, Rosenthal P. Subclinical Atherosclerosis in Pediatric Liver Transplant Recipients: Carotid and Aorta Intima-Media Thickness and Their Predictors. The Journal of pediatrics 2017. PMID: 29224938
Dunavan CP, Rosenthal PJ. "The Way We Were" Ken Warren's Legacy and Modern Investments in Global Health. The American journal of tropical medicine and hygiene 2017. PMID: 29187275
Rasmussen SA, Ceja FG, Conrad MD, Tumwebaze PK, Byaruhanga O, Katairo T, Nsobya SL, Rosenthal PJ, Cooper RA. Changing Antimalarial Drug Sensitivities in Uganda. Antimicrobial agents and chemotherapy 2017. PMID: 28923866
Rani A, Singh A, Gut J, Rosenthal PJ, Kumar V. Microwave-promoted facile access to 4-aminoquinoline-phthalimides: Synthesis and anti-plasmodial evaluation. European journal of medicinal chemistry 2017. PMID: 29174811
Conrad MD, Mota D, Foster M, Tukwasibwe S, Legac J, Tumwebaze P, Whalen M, Kakuru A, Nayebare P, Wallender E, Havlir DV, Jagannathan P, Huang L, Aweeka F, Kamya MR, Dorsey G, Rosenthal PJ. Impact of Intermittent Preventive Treatment During Pregnancy on Plasmodium falciparum Drug Resistance-Mediating Polymorphisms in Uganda. The Journal of infectious diseases 2017. PMID: 28968782
Conrad MD, Mota D, Musiime A, Kilama M, Rek J, Kamya M, Dorsey G, Rosenthal PJ. Comparative Prevalence of Plasmodium falciparum Resistance-Associated Genetic Polymorphisms in Parasites Infecting Humans and Mosquitoes in Uganda. The American journal of tropical medicine and hygiene 2017. PMID: 29016309
Mpimbaza A, Ndeezi G, Katahoire A, Rosenthal PJ, Karamagi C. Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study. The American journal of tropical medicine and hygiene 2017. PMID: 29016322
Katrak S, Murphy M, Nayebare P, Rek J, Smith M, Arinaitwe E, Nankabirwa JI, Kamya M, Dorsey G, Rosenthal PJ, Greenhouse B. Performance of Loop-Mediated Isothermal Amplification for the Identification of Submicroscopic Plasmodium falciparum Infection in Uganda. The American journal of tropical medicine and hygiene 2017. PMID: 29016335
Walakira A, Tukwasibwe S, Kiggundu M, Verra F, Kakeeto P, Ruhamyankaka E, Drakeley C, Dorsey G, Kamya MR, Nsobya SL, Rosenthal PJ. Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2017. PMID: 28939159
Rosenthal PJ, Goraleski KA, Rabinovich NR, Walker PF. Let's Eliminate Diseases, Not Institutes: The Case for the Fogarty International Center. The American journal of tropical medicine and hygiene 2017. PMID: 28990909
