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Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.

  • Read more about Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.

A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.

  • Read more about A Kinase Inhibitor Targeted to mTORC1 Drives Regression in Glioblastoma.

Cholesterol: An Achilles' Heel for Glioblastoma?

  • Read more about Cholesterol: An Achilles' Heel for Glioblastoma?

An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.

  • Read more about An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.

PPAR?: Welcoming the New Kid on the CML Stem Cell Block.

  • Read more about PPAR?: Welcoming the New Kid on the CML Stem Cell Block.

Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.

  • Read more about Combined MYC and P53 defects emerge at medulloblastoma relapse and define rapidly progressive, therapeutically targetable disease.

Drugging MYCN through an allosteric transition in Aurora kinase A.

  • Read more about Drugging MYCN through an allosteric transition in Aurora kinase A.

When deletions gain functions: commandeering epigenetic mechanisms.

  • Read more about When deletions gain functions: commandeering epigenetic mechanisms.

MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.

  • Read more about MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.

EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma.

  • Read more about EGFR phosphorylates tumor-derived EGFRvIII driving STAT3/5 and progression in glioblastoma.

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