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A rare population of CD24(+)ITGB4(+)Notch(hi) cells drives tumor propagation in NSCLC and requires Notch3 for self-renewal.
Distinct neural stem cell populations give rise to disparate brain tumors in response to N-MYC.
Asymmetry-defective oligodendrocyte progenitors are glioma precursors.
Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma.
Non-stem cell origin for oligodendroglioma.
The SPS affair: a complex tale of illicit proliferation.
JunB protects against myeloid malignancies by limiting hematopoietic stem cell proliferation and differentiation without affecting self-renewal.
Single-cell profiling identifies aberrant STAT5 activation in myeloid malignancies with specific clinical and biologic correlates.
Discovery of drug-resistant and drug-sensitizing mutations in the oncogenic PI3K isoform p110 alpha.
A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma.