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Failure of human rhombic lip differentiation underlies medulloblastoma formation.
Brain-restricted mTOR inhibition with binary pharmacology.
RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
A transcriptional switch governs fibroblast activation in heart disease.
Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.
Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects.
Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.
De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation.