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De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation.
Discovery of stimulation-responsive immune enhancers with CRISPR activation.
Divergent clonal selection dominates medulloblastoma at recurrence.
Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.
Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.
Clonal selection drives genetic divergence of metastatic medulloblastoma.
Public health: The toxic truth about sugar.