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Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.
Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects.
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation.
Divergent clonal selection dominates medulloblastoma at recurrence.
Loss of oncogenic Notch1 with resistance to a PI3K inhibitor in T-cell leukaemia.
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy.
Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.
Type 2 innate lymphoid cells control eosinophil homeostasis.
Subgroup-specific structural variation across 1,000 medulloblastoma genomes.