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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities.
Malaria parasites fine-tune mutations to resist drugs.
Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.
Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects.
Thymic tuft cells promote an IL-4-enriched medulla and shape thymocyte development.
Author Correction: Discovery of stimulation-responsive immune enhancers with CRISPR activation.
De novo formation of the biliary system by TGFß-mediated hepatocyte transdifferentiation.
Discovery of stimulation-responsive immune enhancers with CRISPR activation.
Divergent clonal selection dominates medulloblastoma at recurrence.