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UCSF School of Medicine | Department of Pediatrics UCSF Medical Center

Combinatorial targeting of epigenome-modifying enzymes with small molecule drugs synergistically increases HbF.

  • Read more about Combinatorial targeting of epigenome-modifying enzymes with small molecule drugs synergistically increases HbF.

HLH-like toxicities predict poor survival following use of tisagenlecleucel in children and young adults with B-ALL.

  • Read more about HLH-like toxicities predict poor survival following use of tisagenlecleucel in children and young adults with B-ALL.

Histone Deacetylase-6 Modulates the Effects of 4oC Platelets on Vascular Endothelial Permeability.

  • Read more about Histone Deacetylase-6 Modulates the Effects of 4oC Platelets on Vascular Endothelial Permeability.

The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry.

  • Read more about The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry.

Higher doses of tisagenlecleucel associate with improved outcomes: a report from the pediatric real-world CAR consortium.

  • Read more about Higher doses of tisagenlecleucel associate with improved outcomes: a report from the pediatric real-world CAR consortium.

5-Azacytidine depletes HSCs and synergizes with an anti-CD117 antibody to augment donor engraftment in immunocompetent mice.

  • Read more about 5-Azacytidine depletes HSCs and synergizes with an anti-CD117 antibody to augment donor engraftment in immunocompetent mice.

American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation.

  • Read more about American Society of Hematology 2021 guidelines for sickle cell disease: stem cell transplantation.

A simple and robust methylation test for risk stratification of patients with juvenile myelomonocytic leukemia.

  • Read more about A simple and robust methylation test for risk stratification of patients with juvenile myelomonocytic leukemia.

JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β.

  • Read more about JMML tumor cells disrupt normal hematopoietic stem cells by imposing inflammatory stress through overproduction of IL-1β.

Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm.

  • Read more about Successful treatment and integrated genomic analysis of an infant with FIP1L1-RARA fusion-associated myeloid neoplasm.

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