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Biallelic loss-of-function PTPN6 variants lead to inflammatory lung disease and hemolytic anemia.
Immune profiling links autoimmune hepatitis to human herpesvirus 6 and relaxin receptor antigens.
Myeloid-targeting immunotherapies overcome inhibitory barriers in immune-evasive neuroblastoma.
SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency.
Sidestepping SHP2 inhibition.
All eyes on a phosphatase in glioma stem cells.
A SHHecret target of relapsed medulloblastoma: Astrocytes.
Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.
Compromised counterselection by FAS creates an aggressive subtype of germinal center lymphoma.
The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses.