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The epigenetic regulator ATF7ip inhibits Il2 expression, regulating Th17 responses.
Impaired aVß8 and TGFß signaling lead to microglial dysmaturation and neuromotor dysfunction.
PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia.
GPR56/ADGRG1 regulates development and maintenance of peripheral myelin.
Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy.
EXTL3 mutations cause skeletal dysplasia, immune deficiency, and developmental delay.
A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.
Identification of a novel cis-regulatory element essential for immune tolerance.
CCR4 drives ATLL jail break.
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes.