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A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70.
Identification of a novel cis-regulatory element essential for immune tolerance.
CCR4 drives ATLL jail break.
Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance.
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes.
Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia.
Expansion of immunoglobulin-secreting cells and defects in B cell tolerance in Rag-dependent immunodeficiency.
Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15.
Complementation of a pathogenic IFNGR2 misfolding mutation with modifiers of N-glycosylation.
A viral CTL escape mutation leading to immunoglobulin-like transcript 4-mediated functional inhibition of myelomonocytic cells.