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Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice.
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2.
Making or breaking the heart: from lineage determination to morphogenesis.
A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling.
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient.
A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
A functional enhancer suppresses silencing of a transgene and prevents its localization close to centrometric heterochromatin.
The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin.
Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II.