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Effect of Azithromycin treatment on the microbial composition, functional dynamics and resistomes of endocervical, vaginal and rectal microbiomes of women in Fiji with Chlamydia trachomatis infection.
TP53 Inactivation Confers Resistance to the Menin Inhibitor Revumenib in Acute Myeloid Leukemia.
In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer.
MIR192 Upregulates GLP-1 Receptor and Improves Statin-Induced Impairment of Insulin Secretion.
Synergistic RAS-MAPK and AKT Activation in MYC-Driven Tumors via Adjacent PVT1 Rearrangements.
De novo design of Ras isoform selective binders.
C12ORF57: a novel principal regulator of synaptic AMPA currents and excitatory neuronal homeostasis.
Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor.
Haplotype editing with CRISPR/Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL.
Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C.