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A Large Animal Model of Heritable Pulmonary Arterial Hypertension Using Gene-edited BMPR2 Sheep.
COUNTERING AGE-ASSOCIATED ALTERATIONS IN OLIGODENDROCYTE-DERIVED EXTRACELLULAR MATRIX REJUVENATES COGNITION.
Structure-guided design of a targeted autoantibody degrader for neurologic disease.
Genome-wide CRISPRi screen identifies basigin loss as protective in cardiac hypoxia.
A Transcriptional Atlas of Endothelial Cell Zonation Along the Pulmonary Vascular Tree.
Human stem cell models for group 3 medulloblastoma uncover JARID1B as a regulator of the chromatin landscape.
Acute Myeloid Leukemia Relapse after Bromodomain Inhibitor Treatment or Chemotherapy is Characterized by Myc-Ras Transcriptional Remodeling.
STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma.
Pulmonary Vascular Endothelial Dysfunction is Induced by Non-Pulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model.
Daple-FLT3 (CCDC88C-FLT3) gene fusion requires the coiled-coil domain for maximal activation and pericentrosomal localization.