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Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor.
Haplotype editing with CRISPR/Cas9 as a therapeutic approach for dominant-negative missense mutations in NEFL.
Heart tube morphogenesis is regulated by segment-specific gene regulatory networks controlled by MEF2C.
Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation.
Microglia regulate GABAergic neurogenesis in prenatal human brain through IGF1.
Adhesion G protein-coupled receptor ADGRG1 promotes protective microglial response in Alzheimer's disease.
Dark Microglia Are Abundant in Normal Postnatal Development, where they Remodel Synapses via Phagocytosis and Trogocytosis, and Are Dependent on TREM2.
Proteomic profiling of the local and systemic immune response to pediatric respiratory viral infections.
Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4 + cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype.
Leukemia-derived apelin selects endothelial niche clones to promote tumorigenesis.