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Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease.
Postnatal Abrogation of VEGFR2 Blocks Terminal Cap2 Differentiation by Preventing the Developmental Progression from a Capillary Intermediate Cell State.
Integrated single-nuclei and spatial transcriptomic profiling of human sacrococcygeal teratomas reveals heterogeneity in cellular composition and X-chromosome inactivation.
Synthesis errors in oligonucleotides are propagated into the genome by homology-directed repair.
CD38 expression by neonatal human naïve CD4 + T cells shapes their distinct metabolic state and tolerogenic potential.
Multi-selective RAS(ON) Inhibition Targets Oncogenic RAS Mutations and Overcomes RAS/MAPK-Mediated Resistance to FLT3 and BCL2 Inhibitors in Acute Myeloid Leukemia.
Yes-associated Protein Induces Age-dependent Inflammatory Signaling in the Pulmonary Endothelium.
A remarkable expansion of secreted cysteine knot proteins reveals novel virulence factors in the human fungal pathogen Histoplasma.
Effect of Azithromycin treatment on the microbial composition, functional dynamics and resistomes of endocervical, vaginal and rectal microbiomes of women in Fiji with Chlamydia trachomatis infection.
TP53 Inactivation Confers Resistance to the Menin Inhibitor Revumenib in Acute Myeloid Leukemia.