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Human stem cell models for group 3 medulloblastoma uncover JARID1B as a regulator of the chromatin landscape.
Acute Myeloid Leukemia Relapse after Bromodomain Inhibitor Treatment or Chemotherapy is Characterized by Myc-Ras Transcriptional Remodeling.
STING activation reshapes the tumor microenvironment leading to tumor regression in osteosarcoma.
Pulmonary Vascular Endothelial Dysfunction is Induced by Non-Pulsatile Pulmonary Blood Flow in an Ovine Classic Glenn Model.
NOVA: a novel R-package enabling multi-parameter analysis and visualization of neural activity in MEA recordings.
Daple-FLT3 (CCDC88C-FLT3) gene fusion requires the coiled-coil domain for maximal activation and pericentrosomal localization.
In vivo genome-wide CRISPR screens in human T cells to enhance T cell therapy for solid tumors.
Bicistronic CAR T-cells Against CD70 & Active Integrin β2 Overcome Antigen Heterogeneity and Preserve Safety in Acute Myeloid Leukemia.
MitoScribe single-cell molecular recorder logs graded signaling dynamics into mitochondrial DNA.
Reduced TBX5 dosage undermines developmental control of atrial cardiomyocyte identity in a model of human atrial disease.