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Bradykinin contributes to vasogenic edema in murine experimental cerebral malaria.
Redirection of sphingolipid metabolism drives cytoskeletal defects in SPLIS and reveals ROCK inhibition as therapy.
CD38 expression by neonatal human naive CD4+ T cells shapes their distinct metabolic and tolerogenic properties.
TP53/TAU axis regulates microtubule bundling to control alveolar stem cell mediated regeneration.
Pharmacologic inhibition of IRE1α-dependent decay protects alveolar epithelial identity and prevents pulmonary fibrosis in mice.
Clonal expansion of alveolar fibroblast progeny drives pulmonary fibrosis in mouse models.
Neutrophil-specific Shp1 loss results in lethal pulmonary hemorrhage in mouse models of acute lung injury.
CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target.
Unveiling the proteome-wide autoreactome enables enhanced evaluation of emerging CAR T cell therapies in autoimmunity.
Neutralizing IFN-γ autoantibodies are rare and pathogenic in HLA-DRB1*15:02 or 16:02 individuals.