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KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease.
The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas.
Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes.
CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cells.
Schwann cell-derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment.
CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2.
Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency.
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.
Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice.
Broad-spectrum antibodies against self-antigens and cytokines in RAG deficiency.