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Locoregionally administered B7-H3-targeted CAR T cells for treatment of atypical teratoid/rhabdoid tumors.
Viable bacterial colonization is highly limited in the human intestine in utero.
Lentiviral gene therapy for X-linked chronic granulomatous disease.
Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma.
Pan-viral serology implicates enteroviruses in acute flaccid myelitis.
The creatine kinase pathway is a metabolic vulnerability in EVI1-positive acute myeloid leukemia.
Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis.
The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.
Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.