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Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma.
RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer.
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma.
Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis.
Targeting of av integrin identifies a core molecular pathway that regulates fibrosis in several organs.
Autoimmunity's collateral damage: Immunodeficiency hints at autoreactivity to cytokines.
Vessel remodeling in the newborn: platelets fill the gap.
HIV evolution: CTL escape mutation and reversion after transmission.
Defective DNA polymerase-delta proofreading causes cancer susceptibility in mice.
T lymphocytes with a normal ADA gene accumulate after transplantation of transduced autologous umbilical cord blood CD34+ cells in ADA-deficient SCID neonates.