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Lymphatic disorders caused by mosaic, activating KRAS variants respond to MEK inhibition.
ADAM8 signaling drives neutrophil migration and ARDS severity.
αVβ8 integrin targeting to prevent posterior capsular opacification (PCO).
The effects of low-dose IL-2 on Treg adoptive cell therapy in patients with Type 1 diabetes.
SLC26A6-selective inhibitor identified in a small-molecule screen blocks fluid absorption in small intestine.
Repurposing calcium-sensing receptor agonist cinacalcet for treatment of CFTR-mediated secretory diarrheas.
KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice.
Th17 reprogramming of T cells in systemic juvenile idiopathic arthritis.
Immunomodulatory activity of humanized anti-IL-7R monoclonal antibody RN168 in subjects with type 1 diabetes.
Task-related fMRI BOLD response to hyperinsulinemia in healthy older adults.