Honeybadger, a micropeptide encoded by an alternative PVT1 transcript, is a critical negative regulator of RAS-MAPK signaling in MYC-driven tumors.

Paithane U, Tiwari A, Hall B, Tashiro K, Saulnier O, Trinh Q, Soni A, Nakashima T, Bobkov AA, Fujimoto LM, Saraswat M, Sarmashghi S, Hendrikse LD, Masihi MB, Saha S, Ghosh S, James B, Erickson A, Eisemann T, Tzaridis T, Konety B, Dehm SM, Beroukhim R, Chavez L, Largaespada DA, Stein L, Suzuki H, Weiss WA, Yeh J, Zhao J, Wechsler-Reya RJ, Taylor MD, Bagchi A