The UCSF Pediatric Allergy, Immunology, and Bone Marrow Transplantation research programs aim to advance our understanding of complex disorders of the immune system, and to improve outcomes of children with severe allergic, immunologic, malignant, and non-malignant diseases (including bone marrow failure, primary immunodeficiency disorders, immune dysregulatory disorders, and metabolic diseases) using cutting-edge care that includes all available cellular modalities. Some of the exciting work that our researchers are involved in includes:


  • Clinical research on oral immunotherapy for treatment of food allergy
  • Clinical research on epicutaneous immunotherapy for treatment of food allergy
  • Translational research on precision IgE profiling in food allergy
  • Translational research on eosinophilic esophagitis


  • Laboratory and translational research on genetic and molecular basis of immune system disorders
    • Newborn screening for T-cell disorders: spectrum and outcomes
    • Functional analysis of candidate genes in primary T-cell immunodeficiencies
    • Sequencing of newborn blood spot DNA to improve and expand newborn screening
    • Measurements of T-cell production and diversity pre- and post- treatment for severe combined immunodeficiency disease (SCID)
    • CRISPR/Cas9 modification of iPS and hematopoietic stem cells to study T-cell development and treatment for SCID
  • United States Immune Deficiency Network (USIDNET)Registry and clinical research on the natural history of primary immunodeficiencies
  • UCSF Jeffrey Modell Foundation Diagnostic Center for Primary Immunodeficiencies: Laboratory studies to uncover molecular mechanisms of immune defects
  • Laboratory studies on novel genetic susceptibilities to autoimmunity
  • Translational studies on the immune dysregulation of disseminated coccidodiomycosis.
  • Clinical trial of recombinant pegylated adenosine deaminase for patients with ADA-Deficient SCID
  • Clinical research on the psychosocial Impact of infant SCID diagnosis on parents and relatives
  • Clinical research on the optimization of pre-transplant management of patients with chronic granulomatous disease through Immune Deficiency Foundation (IDF)

Bone Marrow Transplant & Cellular Therapy

  • Laboratory and clinical research on the use of genetically-corrected autologous hematopoietic cells (“Gene Therapy”) to treat SCID
  • Clinical research on optimizing the dose of the conditioning agents to be administered during the pre-transplant period
  • Clinical research on non-chemotherapy-based methods to engraft hematopoietic stem cells
  • Clinical research on optimizing the method of ex vivo graft manipulation for mismatched donor transplantation
  • Clinical research on the role of post-transplant immunomodulation in preventing leukemic relapse following allogeneic hematopoietic cell transplantation
  • Clinical research on preventing transplant-related morbidity and mortality, especially that related to opportunistic infections and organ toxicity
  • Expanded access studies of investigational medications and cellular therapies to diagnose and treat rare or severe transplant-related complications, including opportunistic infections and graft-versus-host-disease (GVHD)

In addition, we actively participate in and lead studies through several national clinical trial consortiums, including:

Faculty Research

See Faculty section for more information

Clinical Research Staff

Kenny Truong, Research Nurse Manager
Carol Fraser-Brown, Clinical Research Coordinator
Kevin Magruder, Clinical Research Coordinator
Ying Lu, Clinical Research Coordinator
Jacklyn Alvarez-Sanchez, Clinical Research Coordinator
Jueeli Dahake, Data Manager & Clinical Research Coordinator
To Reach a Member of the Clinical Research Team, please call 415-476-2656


Elizabeth Dunn, Clinical Research Coordinator PIDTC Senior Project Manager
Sharon Kidd, Clinical Research Coordinator,
Kiana Soriano, Clinical Research Coordinator, 
Alison Yip, Clinical Research Coordinator, 
To Reach a Member of the PIDTC Studies Team, please call (415) 502-0203

Research Resources

Search for a Clinical Trial at UCSF Benioff Children’s Hospital
National Directory of Ongoing Clinical Trials:
PIDTC Trials: