Amy Gelfand, MD

Dr. Amy Gelfand is a board-certified child neurologist and Director of Pediatric Headache at UCSF. She specializes in diagnosing and treating children who suffer from a variety of headache disorders, as well as children with childhood periodic syndromes such as abdominal migraine that may be precursors to migraine headache later in life. Her research focuses on the epidemiology and treatment of pediatric migraine and childhood periodic syndromes.

Gelfand received her medical degree from Harvard Medical School. Subsequently, she completed a residency in pediatrics and residency in child neurology at UCSF, then subspecialty fellowship training in pediatric headache at UCSF.

She is the recipient of a teaching award from the UCSF Pediatrics Residents and writing awards from the Resident and Fellows Section of the medical journal, Neurology. Gelfand is a member of the American Academy of Neurology, Child Neurology Society, American Headache Society and International Headache Society.

She is the Principal Investigator of the BRAiN-M Study (Bringing Relief to Adolescents Naturally using Melatonin): http://brain-m.ucsf.edu.
Education
Cert, 2013 - Medicine (Advance Training in Clinical Research), University of California, San Francisco
M.D., 2006 - School of Medicine, Harvard University
Residency, - School of Medicine, University of California, San Francisco
Websites
  1. Özge A, Valeriani M, Guidetti V, Sakai F, Uludüz D, Topaloglu P, Abu-Arafeh I, Gelfand AA, Grazzi L, Wang SJ, Mack KJ, Hikita T, Bruijn J, Orr SL, Hershey AD. Transition of headache care from childhood to adulthood: Focusing needs, barriers, and models of care. A position paper of the IHS Child and Adolescent Committee. Cephalalgia : an international journal of headache 2025. PMID: 40905708



  2. VanderPluym JH, Cheng N, Zhu Y, Wang Z, Morris C, Jones A, Gelfand AA, Gautreaux J. Treatment of medication-overuse headache in children and adolescents: A systematic review. Headache 2025. PMID: 40439245



  3. Goadsby PJ, Evers S, Gelfand AA, Lipton RB, May A, Pozo-Rosich P, Schoenen J, Schwedt TJ, Tassorelli C, Terwindt G, Wang SJ. International Classification of Headache Disorders-4 - Work in progress 2. Cephalalgia : an international journal of headache 2025. PMID: 40239022



  4. Szperka CL, Evans M, Patterson Gentile C, Panigrahi P, Raj NR, Marquez de Prado B, Hershey AD, Gelfand AA. Headache trajectories in children and adolescents with new onset continuous headache. Cephalalgia : an international journal of headache 2024. PMID: 39370854


  5. Schwedt TJ, Pradhan AA, Oshinsky ML, Brin MF, Rosen H, Lalvani N, Charles A, Ashina M, Do TP, Burstein R, Gelfand AA, Dodick DW, Pozo-Rosich P, Lipton RB, Ailani J, Szperka CL, Charleston L, Digre KB, Russo AF, Buse DC, Powers SW, Tassorelli C, Goadsby PJ, Headache Research Priorities Working Group Members. The headache research priorities: Research goals from the American Headache Society and an international multistakeholder expert group. Headache 2024. PMID: 39149968



  6. Gelfand A. Thank you to Dr. Dana Turner. Headache 2024. PMID: 38924081



  7. Goadsby PJ, Evers S, Gelfand AA, Lipton RB, May A, Pozo-Rosich P, Schoenen J, Schwedt TJ, Tassorelli C, Terwindt G, Wang SJ. International Classification of Headache Disorders-4 - Work in Progress 1. Cephalalgia : an international journal of headache 2024. PMID: 38388354


  8. Cohen F, Vallimont J, Gelfand AA. Caution regarding fabricated citations from artificial intelligence. Headache 2023. PMID: 37873980


  9. Gelfand AA, Allen IE, Grimes B, Irwin S, Qubty W, Greene K, Waung M, Powers SW, Szperka CL. Melatonin for migraine prevention in children and adolescents: A randomized, double-blind, placebo-controlled trial after single-blind placebo lead-in. Headache 2023. PMID: 37466211


  10. Canfora M, Pallotto IK, Davis JK, Farley S, Khayata MJ, Hornik CP, Reeve BB, Rikhi A, Gelfand AA, Szperka CL, Kessel S, Pezzuto T, Hammett A, Lemmon ME. More Than a Headache: Lived Experience of Migraine in Youth. Pediatric neurology 2023. PMID: 37451179



  11. Begasse de Dhaem O, Wattiez AS, de Boer I, Pavitt S, Powers SW, Pradhan A, Gelfand AA, Nahman-Averbuch H. Bridging the gap between preclinical scientists, clinical researchers, and clinicians: From animal research to clinical practice. Headache 2023. PMID: 36633108



  12. Gelfand AA. Infantile colic. Handbook of clinical neurology 2023. PMID: 38043962




  13. Gelfand AA, Robbins MS, Szperka CL. New Daily Persistent Headache-A Start With an Uncertain End. JAMA neurology 2022. PMID: 35788252


  14. Gelfand AA, Halker Singh RB, Robbins MS. Worsening migraine: Another casualty of natural disasters. 2022. PMID: 35670096


  15. Khayata MJ, Farley S, Davis JK, Hornik CP, Reeve BB, Rikhi A, Gelfand AA, Szperka CL, Kessel S, Pezzuto T, Hammett A, Lemmon ME. Beyond pain control: Outcome and treatment preferences in pediatric migraine. 2022. PMID: 35524445



  16. Myers KA, Barmherzig R, Raj NR, Berrahmoune S, Ingelmo P, Saint-Martin C, Khan AQ, Kouri M, Morris C, Hershey AD, Kacperski J, Kabbouche MA, Mohamed N, Rao RR, Lagman-Bartolome AM, Gelfand AA, Szperka CL, Orr SL. The spectrum of indomethacin-responsive headaches in children and adolescents. 2022. PMID: 35302385




  17. Hsu WY, Anderson A, Rowles W, Peters KE, Li V, Stone KL, Ashbrook LH, Gelfand AA, Bove RM. Effects of melatonin on sleep disturbances in multiple sclerosis: A randomized, controlled pilot study. 2021. PMID: 34777854


  18. Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GM, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR. Author Correction: Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nature medicine 2021. PMID: 34548659


  19. Abu-Arafeh I, Gelfand AA. The childhood migraine syndrome. Nature reviews. Neurology 2021. PMID: 34040231



  20. Greene KA, Lu V, Luciano MS, Qubty W, Irwin SL, Grimes B, Gelfand AA. Benign paroxysmal torticollis: phenotype, natural history, and quality of life. Pediatric research 2021. PMID: 33564129


  21. Gelfand AA, Ross AC, Pavitt S, Szperka CL, Irwin SL, Bertisch S, Stone KL, Frazier R, Grimes B, Allen IE. Would chronotype change the impact of the relationship between early school schedules and adolescent migraine frequency? A response. Headache 2021. PMID: 33544394


  22. Gelfand AA. Headache refresh 2021. Headache 2021. PMID: 33616933


  23. Gelfand AA, Goadsby PJ. Treating Migraine in Children and Adolescents. JAMA pediatrics 2021. PMID: 32761182


  24. Gelfand AA, Pavitt S, Ross AC, Szperka CL, Irwin SL, Bertisch S, Stone KL, Frazier R, Grimes B, Allen IE. Later high school start time is associated with lower migraine frequency in adolescents. Headache 2020. PMID: 33237581


  25. Cabana MD, Wright P, Scozzafava I, Olarte A, DiSabella M, Liu X, Gelfand AA. Newborn Daily Crying Time Duration. Journal of pediatric nursing 2020. PMID: 33181371



  26. Orr SL, Gelfand AA, Hranilovich J, Irwin SL, Kabbouche M, Lagman-Bartolome AM, Lavell C, O'Brien HL, Rajapakse T, Rao R, Szperka C, Werner K, VanderPluym J, Yonker M, Hershey A. The Development of the Medical Transfer Packet for Transition of Care of the Pediatric Patient with Headache. Headache 2020. PMID: 32969505


  27. Gelfand AA, Ross AC, Irwin SL, Greene KA, Qubty WF, Allen IE. Melatonin for Acute Treatment of Migraine in Children and Adolescents: A Pilot Randomized Trial. Headache 2020. PMID: 32965037



  28. VanderPluym J, Gautreaux J, Burch R, Whitaker E, Roberts J, Turner DP, Gelfand AA. Evidence Regarding Medication Overuse Headache in Children and Adolescents: Protocol for a Systematic Review. Headache 2020. PMID: 31913513



  29. Hornik CP, Gelfand AA, Szperka CL, Pezzuto T, Utevsky A, Kessel S, McCune S, Alexander JJ, Benjamin DK, Cohen-Wolkowiez M. Development of a Prospective Real-World Data Clinical Registry of Children and Adolescents With Migraine. Headache 2019. PMID: 31758549


  30. Turner SB, Rende EK, Pezzuto T, Weaver S, Henderlong-Kropp A, Greene KA, Bicknese AR, Dilts JJ, Gautreaux J, Victorio MCC, Strauss LD, Lagman-Bartolome AM, Szperka CL, Yonker M, Hershey AD, Gelfand AA. Pediatric Migraine Action Plan (PedMAP). Headache 2019. PMID: 31710105


  31. Turner SB, Rende EK, Szperka CL, Hershey AD, Gelfand AA. The Development of the Pediatric Migraine Action Plan (PedMAP). Headache 2019. PMID: 31710107


  32. Schubert RD, Hawes IA, Ramachandran PS, Ramesh A, Crawford ED, Pak JE, Wu W, Cheung CK, O'Donovan BD, Tato CM, Lyden A, Tan M, Sit R, Sowa GA, Sample HA, Zorn KC, Banerji D, Khan LM, Bove R, Hauser SL, Gelfand AA, Johnson-Kerner BL, Nash K, Krishnamoorthy KS, Chitnis T, Ding JZ, McMillan HJ, Chiu CY, Briggs B, Glaser CA, Yen C, Chu V, Wadford DA, Dominguez SR, Ng TFF, Marine RL, Lopez AS, Nix WA, Soldatos A, Gorman MP, Benson L, Messacar K, Konopka-Anstadt JL, Oberste MS, DeRisi JL, Wilson MR. Pan-viral serology implicates enteroviruses in acute flaccid myelitis. Nature medicine 2019. PMID: 31636453



  33. Hershey AD, Oskoui M, Pringsheim T, Holler-Managan Y, Potrebic S, Billinghurst L, Gloss D, Licking N, Sowell M, Victorio MC, Gersz E, Vrijsen E, Zanitsch H, Yonker M, Mack K, Gelfand AA, Szperka CL, Powers SW. New Guidelines: Interpretation, Application and the Future. Headache 2019. PMID: 31529478


  34. Greene K, Irwin SL, Gelfand AA. Pediatric Migraine: An Update. Neurologic clinics 2019. PMID: 31563234


  35. Gelfand AA, Buse DC, Cabana MD, Grimes B, Goadsby PJ, Allen IE. The Association Between Parental Migraine and Infant Colic: A Cross-Sectional, Web-Based, U.S. Survey Study. Headache 2019. PMID: 31222745


  36. Hall AL, Karvounides D, Gelfand AA, Mankin H, Kessel S, Corroo J, Malavolta CP, Pezzuto T, Chadehumbe M, Szperka CL. Improving the Patient Experience With Migraine Camp, a One-Day Group Intervention for Adolescents With Chronic Headache and Their Parents. Headache 2019. PMID: 31165479


  37. Berger A, Litwin J, Allen IE, Qubty W, Irwin S, Waung M, Gelfand AA. Preliminary Evidence that Melatonin Is not a Biomarker in Children and Adolescents With Episodic Migraine. Headache 2019. PMID: 31054199


  38. Gelfand AA, Pavitt S, Greene K, Szperka CL, Irwin S, Grimes B, Allen IE. High School Start Time and Migraine Frequency in High School Students. Headache 2019. PMID: 31016722


  39. Gelfand AA, Loder E. Potential Benefits of Migraine-What Is It Good For? JAMA neurology 2019. PMID: 30556821



  40. Szperka CL, VanderPluym J, Orr SL, Oakley CB, Qubty W, Patniyot I, Lagman-Bartolome AM, Morris C, Gautreaux J, Victorio MC, Hagler S, Narula S, Candee MS, Cleves-Bayon C, Rao R, Fryer RH, Bicknese AR, Yonker M, Hershey AD, Powers SW, Goadsby PJ, Gelfand AA. Recommendations on the Use of Anti-CGRP Monoclonal Antibodies in Children and Adolescents. Headache 2018. PMID: 30324723







  41. Qubty W, Patniyot I, Gelfand A. Telemedicine in a pediatric headache clinic: A prospective survey. Neurology 2018. PMID: 29626180


  42. Gelfand JM, Gelfand AA, Goadsby PJ, Benn BS, Koth LL. Migraine is common in patients with sarcoidosis. Cephalalgia : an international journal of headache 2018. PMID: 29580067


  43. Irwin SL, Qubty W, Allen IE, Patniyot I, Goadsby PJ, Gelfand AA. Transcranial Magnetic Stimulation for Migraine Prevention in Adolescents: A Pilot Open-Label Study. Headache 2018. PMID: 29528485


  44. Starling AJ, Tepper SJ, Marmura MJ, Shamim EA, Robbins MS, Hindiyeh N, Charles AC, Goadsby PJ, Lipton RB, Silberstein SD, Gelfand AA, Chiacchierini RP, Dodick DW. A multicenter, prospective, single arm, open label, observational study of sTMS for migraine prevention (ESPOUSE Study). Cephalalgia : an international journal of headache 2018. PMID: 29504483


  45. Buse DC, Powers SW, Gelfand AA, VanderPluym JH, Fanning KM, Reed ML, Adams AM, Lipton RB. Adolescent Perspectives on the Burden of a Parent's Migraine: Results from the CaMEO Study. Headache 2018. PMID: 29355924


  46. Özge A, Abu-Arafeh I, Gelfand AA, Goadsby PJ, Cuvellier JC, Valeriani M, Sergeev A, Barlow K, Uludüz D, Yalin OÖ, Faedda N, Lipton RB, Rapoport A, Guidetti V. Experts' opinion about the pediatric secondary headaches diagnostic criteria of the ICHD-3 beta. The journal of headache and pain 2017. PMID: 29285571


  47. Özge A, Faedda N, Abu-Arafeh I, Gelfand AA, Goadsby PJ, Cuvellier JC, Valeriani M, Sergeev A, Barlow K, Uludüz D, Yalin OÖ, Lipton RB, Rapoport A, Guidetti V. Experts' opinion about the primary headache diagnostic criteria of the ICHD-3rd edition beta in children and adolescents. The journal of headache and pain 2017. PMID: 29285570


  48. Gelfand AA, Qubty W, Goadsby PJ. Pediatric Migraine Prevention-First, Do No Harm. JAMA neurology 2017. PMID: 28628697


  49. Bear JJ, Gelfand AA, Goadsby PJ, Bass N. Occipital headaches and neuroimaging in children. Neurology 2017. PMID: 28667183



  50. Gelfand AA, Qubty W, Patniyot I, Grimes B, Pletcher MJ, Goadsby PJ, Cummings SR. Home-Based Trials in Adolescent Migraine: A Randomized Clinical Trial. JAMA neurology 2017. PMID: 28437521





  51. Gelfand AA, Johnson H, Lenaerts ME, Litwin JR, De Mesa C, Bogduk N, Goadsby PJ. Neck-Tongue syndrome: A systematic review. Cephalalgia : an international journal of headache 2017. PMID: 28100071






  52. Johnson HF, Goadsby PJ, Gelfand AA. Predictors of Triptan Response in Pediatric Migraine. Pediatric neurology 2016. PMID: 26968976


  53. Eller M, Gelfand AA, Riggins NY, Shiboski S, Schankin C, Goadsby PJ. Exacerbation of headache during dihydroergotamine for chronic migraine does not alter outcome. Neurology 2016. PMID: 26843569





  54. Gelfand AA. Infant Colic. Seminars in pediatric neurology 2015. PMID: 27017027



  55. Pressman A, Jacobson A, Eguilos R, Gelfand A, Huynh C, Hamilton L, Avins A, Bakshi N, Merikangas K. Prevalence of migraine in a diverse community--electronic methods for migraine ascertainment in a large integrated health plan. Cephalalgia : an international journal of headache 2015. PMID: 26069243



  56. Gelfand AA, Fullerton HJ, Jacobson A, Sidney S, Goadsby PJ, Kurth T, Pressman A. Is migraine a risk factor for pediatric stroke? Cephalalgia : an international journal of headache 2015. PMID: 25754176






  57. Young-Lin N, Shalev S, Glenn OA, Gardner M, Lee C, Wynshaw-Boris A, Gelfand AA. Teaching neuroimages: infant with glutaric aciduria type 1 presenting with infantile spasms and hypsarrhythmia. Neurology 2013. PMID: 24323445







  58. Gelfand AA, Croen LA, Torres AR, Wu YW. Genetic risk factors for perinatal arterial ischemic stroke. Pediatric neurology 2013. PMID: 23290018



  59. Gelfand AA, Thomas KC, Goadsby PJ. Before the headache: infant colic as an early life expression of migraine. Neurology 2012. PMID: 22972642


  60. Gelfand AA, Goadsby PJ. Primary sex headache in adolescents. Pediatrics 2012. PMID: 22753551




  61. Wu YW, Croen LA, Vanderwerf A, Gelfand AA, Torres AR. Candidate genes and risk for CP: a population-based study. Pediatric research 2011. PMID: 21857382


  62. Pham CB, Kratz JR, Jelin AC, Gelfand AA. Child neurology: Brachial plexus birth injury: what every neurologist needs to know. Neurology 2011. PMID: 21844527


  63. Gelfand AA, Sznewajs A, Glass HC, Jelin AC, Sherr EH. Clinical Reasoning: An encephalopathic 3-day-old infant. Neurology 2011. PMID: 21727263



  64. Gelfand AA, Fullerton HJ, Goadsby PJ. Child neurology: Migraine with aura in children. Neurology 2010. PMID: 20679627



  65. Gelfand AA. A piece of my mind. Triggers. JAMA 2006. PMID: 16968834