Marie - Coralie Cornet, MD

Dr. Marie Cornet is a Neonatologist at Benioff Children Hospital, University of California, San Francisco. She cares for premature babies and term neonates who require intensive care at birth. She is part of the Neuro-intensive Care Nursery (NICN) leadership team. Her research focuses on neonatal neurology, term encephalopathy, and neonatal seizures.

Dr. Cornet joined the Division of Neonatology at UCSF in 2018. She completed her pediatric residency and obtained a PhD in medical science at the University of Louvain. She did a year of Neonatology in London before moving to UCSF to pursue research in neonatal seizures supported by a Belgian American Educational Grant. She completed her neonatology Fellowship and advanced training in clinical research at UCSF.

Dr. Cornet has published several studies of early predictors and signs of seizures and hypoxic-ischemic encephalopathy. She also studied how maternal treatment may influence neonatal adaptation at birth and the risk of hypoxic-ischemic encephalopathy. Her current work focuses on the role of maternal infection and inflammation on neonatal and neurodevelopmental outcomes. Dr. Cornet has received funding from the UCSF Newborn Brain Research Institute, the Thrasher Foundation, and the NIH.
Education
09/2022 - Neonatology, University of California
PhD, 05/2022 - Medecine, University of Louvain
10/2015 - Pediatrics, University of Louvain
MD, 06/2010 - Medecine, University of Louvain
Honors and Awards
  • Bhatt Ramanathan Award for outstanding research, California Academy of Neonatologist, 2023
  • K23: Mentored Patient-Oriented Research Career Development Award, NICHD, 2022
  • Melvin M. Grumbach Award for Excellence in Research, UCSF, 2022
  • Early Career Award, Thrasher Research Fund, 2021
  • Newborn Brain Research Institute Innovation Award, UCSF, 2021

  1. Cornet MC, Gonzalez FF, Glass HC, Wu TW, Wisnowski JL, Li Y, Heagerty P, Juul SE, Wu YW. Chorioamnionitis and Two-Year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2024. PMID: 39577760


  2. Cornet MC, Numis AL, Monsell SE, Chan NH, Gonzalez FF, Comstock BA, Juul SE, Wusthoff CJ, Wu YW, Glass HC. Assessing Early Severity of Hypoxic-Ischemic Encephalopathy: The Role of Electroencephalogram Background in Addition to Sarnat Exam. The Journal of pediatrics 2024. PMID: 39557386


  3. Bernardo D, Kim J, Cornet MC, Numis AL, Scheffler A, Rao VR, Amorim E, Glass HC. Machine learning for forecasting initial seizure onset in neonatal hypoxic-ischemic encephalopathy. Epilepsia 2024. PMID: 39495029


  4. Cornet MC, Kuzniewicz MW, Scheffler AW, Gaw SL, Yeh P, Newman TB, Wu YW. Epidural Analgesia During Labor and Neonatal Hypoxic-Ischemic Encephalopathy. JAMA network open 2024. PMID: 39283635


  5. Gonzalez FF, Monsell SE, Cornet MC, Glass H, Wisnowski J, Mathur A, McKinstry R, Li Y, Wu TW, Mayock DE, Heagerty PJ, Juul SE, Wu YW. Perinatal arterial ischemic stroke diagnosed in infants receiving therapeutic hypothermia for hypoxic-ischemic encephalopathy. Pediatric research 2024. PMID: 39191951


  6. Cornet MC, Wu YW, Forquer H, Avalos LA, Sriram A, Scheffler AW, Newman TB, Kuzniewicz MW. Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study. Archives of disease in childhood. Fetal and neonatal edition 2023. PMID: 38071585


  7. Kearney RE, Wu YW, Vargas-Calixto J, Kuzniewicz MW, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick PA. Construction of a comprehensive fetal monitoring database for the study of perinatal hypoxic ischemic encephalopathy. MethodsX 2024. PMID: 38524309


  8. Morell AS, Monsell SE, Cornet MC, Wisnowski JL, McKinstry RC, Mathur AM, Li Y, Glass HC, Gonzalez FF, Mayock DE, Benninger KL, Van Meurs KP, Lampland AL, Wu TW, Riley D, Mietzsch U, Chalak L, Flibotte J, Weitkamp JH, Ahmad KA, Yanowitz TD, Baserga M, Merhar S, Rao R, Sokol GM, Comstock BA, Heagerty PJ, Juul SE, Wu YW. Genetic and Congenital Anomalies in Infants With Hypoxic-Ischemic Encephalopathy. Pediatric neurology 2024. PMID: 38518503


  9. Vargas-Calixto J, Wu YW, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick P, Kearney R. Prediction of Hypoxic-Ischemic Encephalopathy Using Events in Fetal Heart Rate and Uterine Pressure. Computing in cardiology 2023. PMID: 39364002


  10. Vargas-Calixto J, Wu YW, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick PA, Kearney RE. Accounting for Nulliparity in the Prediction of Hypoxic-Ischemic Encephalopathy Using Cardiotocography. ... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics 2023. PMID: 38031586


  11. Gonzalez FF, Voldal E, Comstock BA, Mayock DE, Goodman AM, Cornet MC, Wu TW, Redline RW, Heagerty P, Juul SE, Wu YW. Placental Histologic Abnormalities and 2-Year Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy. Neonatology 2023. PMID: 37742617


  12. Cornet MC, Kuzniewicz M, Scheffler A, Forquer H, Hamilton E, Newman TB, Wu YW. Perinatal Hypoxic-Ischemic Encephalopathy: Incidence Over Time Within a Modern US Birth Cohort. Pediatric neurology 2023. PMID: 37883841


  13. Vargas-Calixto J, Wu Y, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick PA, Kearney RE. Timely Detection of Infants at Risk of Intrapartum Acidosis and Hypoxic-Ischemic Encephalopathy Using Cardiotocography. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2023. PMID: 38083649


  14. Pijpers JA, Au PYB, Weeke LC, Vein AA, Smit LS, Vilan A, Jacobs E, de Vries LS, Steggerda SJ, Cilio MR, Carapancea E, Cornet MC, Appendino JP, Peeters-Scholte CMPCD. Early recognition of characteristic conventional and amplitude-integrated EEG patterns of seizures in SCN2A and KCNQ3-related epilepsy in neonates. Seizure 2023. PMID: 37429183


  15. Engel C, Valence S, Delplancq G, Maroofian R, Accogli A, Agolini E, Alkuraya FS, Baglioni V, Bagnasco I, Becmeur-Lefebvre M, Bertini E, Borggraefe I, Brischoux-Boucher E, Bruel AL, Brusco A, Bubshait DK, Cabrol C, Cilio MR, Cornet MC, Coubes C, Danhaive O, Delague V, Denommé-Pichon AS, Di Giacomo MC, Doco-Fenzy M, Engels H, Cremer K, Gérard M, Gleeson JG, Heron D, Goffeney J, Guimier A, Harms FL, Houlden H, Iacomino M, Kaiyrzhanov R, Kamien B, Karimiani EG, Kraus D, Kuentz P, Kutsche K, Lederer D, Massingham L, Mignot C, Morris-Rosendahl D, Nagarajan L, Odent S, Ormières C, Partlow JN, Pasquier L, Penney L, Philippe C, Piccolo G, Poulton C, Putoux A, Rio M, Rougeot C, Salpietro V, Scheffer I, Schneider A, Srivastava S, Straussberg R, Striano P, Valente EM, Venot P, Villard L, Vitobello A, Wagner J, Wagner M, Zaki MS, Zara F, Lesca G, Yassaee VR, Miryounesi M, Hashemi-Gorji F, Beiraghi M, Ashrafzadeh F, Galehdari H, Walsh C, Novelli A, Tacke M, Sadykova D, Maidyrov Y, Koneev K, Shashkin C, Capra V, Zamani M, Van Maldergem L, Burglen L, Piard J. BRAT1-related disorders: phenotypic spectrum and phenotype-genotype correlations from 97 patients. European journal of human genetics : EJHG 2023. PMID: 37344571


  16. Juul SE, Comstock BA, Cornet MC, Gonzalez FF, Mayock DE, Glass HC, Schreiber MD, Heagerty PJ, Wu YW. Safety of High Dose Erythropoietin Used with Therapeutic Hypothermia as Treatment for Newborn Hypoxic-Ischemic Encephalopathy: Secondary Analysis of the HEAL Randomized Controlled Trial. The Journal of pediatrics 2023. PMID: 37019334


  17. Vargas-Calixto J, Wu Y, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick P, Kearney R. The Nonlinear Dynamic Response of Intrapartum Fetal Heart Rate to Uterine Pressure. Computing in cardiology 2023. PMID: 38037619


  18. Chan S, Duck M, Frometa K, Liebowitz M, Rosenstein MG, Tesfalul M, Cornet MC, Kramer KP. Improving the Rate of Delayed Cord Clamping in Preterm Infants: A Quality Improvement Project. Hospital pediatrics 2023. PMID: 36946125


  19. Carapancea E, Cornet MC, Milh M, De Cosmo L, Huang EJ, Granata T, Striano P, Ceulemans B, Stein A, Morris-Rosendahl D, Conti G, Mitra N, Raymond FL, Rowitch DH, Solazzi R, Vercellino F, De Liso P, D'Onofrio G, Boniver C, Danhaive O, Carkeek K, Salpietro V, Weckhuysen S, Fedrigo M, Angelini A, Castellotti B, Lederer D, Benoit V, Raviglione F, Guerrini R, Dilena R, Cilio MR. Clinical and Neurophysiological Phenotypes in Neonates With BRAT1 Encephalopathy. Neurology 2023. PMID: 36599696


  20. Cornet MC, Grose C, Vexler Z, Wu YW, Fullerton HJ. The Role of Infection and Inflammation in the Pathogenesis of Pediatric Arterial Ischemic Stroke. Seminars in pediatric neurology 2022. PMID: 36456035


  21. Vargas-Calixto J, Wu Y, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick PA, Kearney RE. Multi-Chain Semi-Markov Analysis of Intrapartum Cardiotocography. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2022. PMID: 36086200


  22. Cornet MC, Li Y, Simmons RL, Baker A, Fullerton HJ, Hetts SW, Glass HC. Outcome of Neonates Presenting With Severe Cardiac Failure due to Cerebral Arteriovenous Fistula. 2022. PMID: 35462109


  23. Li Y, Wisnowski JL, Chalak L, Mathur AM, McKinstry RC, Licona G, Mayock DE, Chang T, Van Meurs KP, Wu TW, Ahmad KA, Cornet MC, Rao R, Scheffler A, Wu YW. Mild hypoxic-ischemic encephalopathy (HIE): timing and pattern of MRI brain injury. 2022. PMID: 35354930


  24. Cornet MC, Kemper AR, Maisels MJ, Watchko J, Newman TB. Neonatal hyperbilirubinemia and bilirubin neurotoxicity: what can be learned from the database analysis? 2022. PMID: 35136201


  25. Vargas-Calixto J, Wu Y, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick P, Kearney R. Temporal Evolution of Intrapartum Fetal Heart Rate Features. Computing in cardiology 2021. PMID: 38013902


  26. Cornet MC, Morabito V, Lederer D, Glass HC, Ferrao Santos S, Numis AL, Ferriero DM, Sands TT, Cilio MR. Neonatal presentation of genetic epilepsies: Early differentiation from acute provoked seizures. Epilepsia 2021. PMID: 34153113


  27. El Kosseifi C, Cornet MC, Cilio MR. Neonatal Developmental and Epileptic Encephalopathies. Seminars in pediatric neurology 2019. PMID: 31813518


  28. Ritter-Makinson S, Clemente-Perez A, Higashikubo B, Cho FS, Holden SS, Bennett E, Chkhaidze A, Eelkman Rooda OHJ, Cornet MC, Hoebeek FE, Yamakawa K, Cilio MR, Delord B, Paz JT. Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome. Cell reports 2019. PMID: 30673603


  29. Ritter-Makinson S, Clemente-Perez A, Higashikubo B, Cho FS, Holden SS, Bennett E, Chkhaidze A, Eelkman Rooda OHJ, Cornet MC, Hoebeek FE, Yamakawa K, Cilio MR, Delord B, Paz JT. Augmented Reticular Thalamic Bursting and Seizures in Scn1a-Dravet Syndrome. Cell reports 2019. PMID: 30605686


  30. Cornet MC, Cilio MR. Genetics of neonatal-onset epilepsies. Handbook of clinical neurology 2019. PMID: 31324323


  31. Cornet MC, Pasupuleti A, Fang A, Gonzalez F, Shimotake T, Ferriero DM, Glass HC, Cilio MR. Predictive value of early EEG for seizures in neonates with hypoxic-ischemic encephalopathy undergoing therapeutic hypothermia. Pediatric research 2018. PMID: 29895836


  32. Cornet MC, Sands TT, Cilio MR. Neonatal epilepsies: Clinical management. Seminars in fetal & neonatal medicine 2018. PMID: 29426806


  33. Cornet MC, Maton P, Langhendries JP, Marion W, Marguglio A, Smeets S, Vervoort A, François A. [Use of therapeutic hypothermia in sudden unexpected postnatal collapse]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 2014. PMID: 25089044


  34. Blumental S, Huisman E, Cornet MC, Ferreiro C, De Schutter I, Reynders M, Wybo I, Kabamba-Mukadi B, Armano R, Hermans D, Nassogne MC, Mahadeb B, Fonteyne C, Van Berlaer G, Levy J, Moulin D, Vergison A, Malfroot A, Lepage P. Pandemic A/H1N1v influenza 2009 in hospitalized children: a multicenter Belgian survey. BMC infectious diseases 2011. PMID: 22060843