Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies.

PloS one
2021
https://researcherprofiles.org/profile/432739357
34324576
Wadhwa A, Yin S, Freeman B, Hershow RB, Killerby M, Yousaf AR, Lester S, Mills L, Buono SA, Pomeroy M, Owusu D, Chu VT, Tate JE, Bhattacharyya S, Hall P, Thornburg NJ, Kirking HL
Abstract

Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott ArchitectTM SARS-CoV-2 IgG assay indicated that the assays had high concordance, with rare paired discordant tests results.

Journal Issue
Volume 16 of Issue 7