Jason Pomerantz, MD

Jason Pomerantz, MD, FACS, FAAP is Associate Professor in Residence in Plastic and Reconstructive Surgery at University of California San Francisco. He is a highly regarded and respected surgeon-scientist who is devoted to clinical and basic science teaching and mentoring. Dr. Pomerantz developed his subspecialty in pediatric and adult craniofacial surgery and is Surgical Director of UCSF’s Craniofacial Center. He is one of two craniofacial surgeons at UCSF and the sole craniofacial surgeon providing care of facial trauma and craniofacial reconstruction at Zuckerberg San Francisco General Hospital. Additionally, Dr. Pomerantz is one of four surgeons at UCSF performing facial gender affirmation surgery, and the only surgeon to perform these procedures at ZSFGH, where he led and performed the first series of facial gender affirmation operations for an underserved population at a county hospital in the United States. He also is Co-Chair of the Department of Surgery Research Committee at UCSF, overseeing the department research activities focused on student and resident scholarly work and Director of Pomerantz Laboratory. The Pomerantz Laboratory studies basic and translational aspects of tissue regeneration. Their research program is closely related to regenerative medicine. With foundations in muscle and cancer biology, they are investigating regenerative mechanisms including stem cell function and de-differentiation. By employing model organisms such as zebrafish and mouse and extending discoveries to human cells and tissues, they aim to gain fundamental insight that can be translated into clinical advances, most notably solving the structural and reconstructive problems of the limbs, face, and head.
Education
2009 - Craniofacial Surgery, Fellowship, University of Washington
2008 - Plastic Surgery, Residency, University of California, San Francisco
2006 - Postdoctoral Fellowship, Regeneration Biology, Stanford University
2003 - General Surgery, Residency, University of California, San Francisco
2001 - General Surgery, Internship, University of California, San Francisco
MD, 2000 - Medicine, Albert Einstein College of Medicine
1998 - Research Fellowship, Howard Hughes Medical Institute, Albert Einstein College of Medicine
BA, 1994 - Biology, University of Pennsylvania
Honors and Awards
  • Teaching Award for Clinical Faculty, UCSF School of Medicine, Medical Student Class of 2022, University of California, San Francisco, 2022
  • American Society of Maxillofacial Surgeons, CRANIO Fellowship, 2013
  • New Faculty Physician Scientist Award, California Institute of Regenerative Medicine, 2013
  • American Society of Maxillofacial Surgeons, ASMS Merck Scholarship, 2007
  • Clifford C. Snyder, M.D. Award, Plastic Surgery Research Council, 2006
  • PSEF Scientific Essay Contest D. Ralph Millard, MD Investigator Award Coauthor. First Place, 2005
  • Distinction in Molecular Biology, Albert Einstein College of Medicine, 2000
  • Continued Support, Completion of Medical Studies, 1998
  • Continued Support, Additional Research Year, 1997
  • Outstanding Poster Presentation, Thirteenth Annual Meeting on Oncogenes, Frederick, Maryland, 1997
  • Medical Student Research Training Fellowship, Howard Hughes Medical Institute, 1996
  • Honors Degree in Biology, University of Pennsylvania, 1994
  • Magna Cum Laude, University of Pennsylvania, 1994
  • Dean's List, University of Pennsylvania, 1991
Websites

  1. Rohrer L, Striedinger K, Pomerantz J. Rodent Model of Masseter Volumetric Muscle Loss for Studying Bioengineering Materials. Journal of visualized experiments : JoVE 2024. PMID: 38884461


  2. Rohrer L, Kato S, Browne S, Striedinger K, Healy KE, Pomerantz JH. Acrylated Hyaluronic-Acid Based Hydrogel for the Treatment of Craniofacial Volumetric Muscle Loss. Tissue engineering. Part A 2024. PMID: 38534963


  3. Do A, Rorison E, Borucki A, Shibata GS, Pomerantz JH, Hoffman WY. Opioid-free Pain Management after Cleft Lip Repair. Plastic and reconstructive surgery. Global open 2023. PMID: 37691705


  4. Danial E, Rios J, Badiee R, Rosenbluth G, Pomerantz JH. Analyzing Linguistic Disparities in Telehealth Care Outcomes at a Multidisciplinary Craniofacial Center. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2023. PMID: 37605606


  5. Perkins IU, Tan SY, McCalmont TH, Chou PM, Mully TW, Gerami P, Pomerantz JH, Reyes-Múgica M, Balkin DM, Kruse LL, Huang B, Reichek JL, Gangopadhyay N, Chiosea S, Green JR, Chamlin SL, Frieden IJ, Bastian BC, Yeh I. Melanoma in infants, caused by a gene fusion involving the anaplastic lymphoma kinase (ALK). Pigment cell & melanoma research 2023. PMID: 37475109


  6. Barruet E, Striedinger K, Marangoni P, Pomerantz JH. Loss of transcriptional heterogeneity in aged human muscle stem cells. PloS one 2023. PMID: 37192223


  7. Braun M, Pomerantz JH, Hoffman WY, Mathes EF. Long-pulsed neodymium-doped yttrium aluminum garnet for hair reduction in pediatric microtia repair. Pediatric dermatology 2023. PMID: 36807931


  8. Zebolsky AL, Gulati A, Badiee RK, Pardo ST, Deutsch MB, Knott PD, Park AM, Pomerantz JH, Hoffman WY, Seth R. Patient-Reported Outcomes in Gender-Affirming Facial Surgery: Recommendations from a Multidisciplinary Gender Health Panel. Facial plastic surgery & aesthetic medicine 2023. PMID: 36795977


  9. Alcon A, Badiee RK, Barnes LL, Pardo ST, Zevin B, Pomerantz JH. Gender-Affirming Facial Feminization Surgery at a Public, Safety-Net Hospital: A Single-Center Early Experience. The Journal of craniofacial surgery 2022. PMID: 36210502


  10. Badiee RK, Maru J, Yang SC, Alcon A, Rosenbluth G, Pomerantz JH. Racial and Socioeconomic Disparities in Prompt Craniosynostosis Workup and Treatment. The Journal of craniofacial surgery 2022. PMID: 36409867


  11. Logjes RJ, Breugem CC, Pomerantz JH. Letter: Robin Sequence: 5-Year Speech Outcomes-A Case-Control Study. Plastic and reconstructive surgery 2022. PMID: 35708683


  12. Badiee RK, Popowitz E, Mark IT, Alcon A, Hwang J, Rorison E, Auguste KI, Hoffman WY, Sun PP, Pomerantz JH. Superior Long-term Appearance of Strip Craniectomy Compared with Cranial Vault Reconstruction in Metopic Craniosynostosis. 2022. PMID: 35169528


  13. Badiee RK, Yang SC, Alcon A, Weeks AC, Rosenbluth G, Pomerantz JH. Disparities in Timing of Alveolar Bone Grafting and Dental Reconstruction in Patients With Clefts. 2022. PMID: 35044260


  14. Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, Pomerantz JH, Hsiao EC. Modeling the ACVR1R206H mutation in human skeletal muscle stem cells. 2021. PMID: 34755602


  15. Ryan Badiee, Emma Popowitz, Ian Mark, Joan Hwang, Eve Rorison, Kurtis Auguste, William Y. Hoffman, Peter P. Sun, Jason H. Pomerantz. Comparing Long-term Outcomes of Open Cranial Vault Reconstruction and Minimally Invasive Strip Craniectomy in Metopic Craniosynostosis. Plastic & Reconstructive Surgery Global Open 2021. PMID:


  16. Andre Alcon, Ryan K. Badiee, Laura L. Barnes, Seth T. Pardo, Barry Zevin, Jason H. Pomerantz. An Early Experience with Gender-affirming Facial Feminization Surgery at a Public, Safety-net Hospital. Plastic & Reconstructive Surgery Global Open 2021. PMID:


  17. Badiee RK, Popowitz E, Mark I, Hwang J, Rorison E, Auguste KI, Hoffman WY, Sun PP, and Pomerantz JH.. Comparing Long-term Outcomes of Open Cranial Vault Reconstruction and Minimally Invasive Strip Craniectomy in Metopic Craniosynostosis Plastic and Reconstructive Surgery - Global Open. 2021. PMID:


  18. Striedinger K, Barruet E, Pomerantz JH. Purification and preservation of satellite cells from human skeletal muscle. STAR protocols 2021. PMID: 33554137


  19. Logjes RJH, Upton S, Mendelsohn BA, Badiee RK, Breugem CC, Hoffman WY, Pomerantz JH. Long-term Speech Outcomes of Cleft Palate Repair in Robin Sequence versus Isolated Cleft Palate. Plastic and reconstructive surgery. Global open 2021. PMID: 33564582


  20. Barruet E, Garcia SM, Wu J, Morales BM, Tamaki S, Moody T, and Pomerantz JH.. ACVR1R206H increases osteogenic/ECM gene expression and impairs myofiber formation in human skeletal muscle stem cells bioRxiv 2021. PMID:


  21. Callen AL, Badiee RK, Phelps A, Potigailo V, Wang E, Lee S, Talbott J, Glastonbury C, Pomerantz JH, Narvid J. Facial Feminization Surgery: Key CT Findings for Preoperative Planning and Postoperative Evaluation. AJR. American journal of roentgenology 2020. PMID: 33377414


  22. Callen AL, Badiee RK, Phelps A, Potigailo V, Wang E, Lee S, Talbott J, Glastonbury C, Pomerantz JH, Narvid J. Facial Feminization Surgery: Key CT Findings for Preoperative Planning and Postoperative Evaluation. AJR. American journal of roentgenology 2021. PMID: 33377802


  23. Wong A, Garcia SM, Tamaki S, Striedinger K, Barruet E, Hansen SL, Young DM, Pomerantz JH. Satellite cell activation and retention of muscle regenerative potential after long-term denervation. Stem cells (Dayton, Ohio) 2020. PMID: 33326654


  24. Badiee RK, Willsher H, Rorison E, Langham M, Donnelly A, Rosenbluth G, Pomerantz JH. Transitioning Multidisciplinary Craniofacial Care to Telehealth during the COVID-19 Pandemic: A Single Center Experience. Plastic and reconstructive surgery. Global open 2020. PMID: 33133981


  25. Lee S, Hesse R, Tamaki S, Garland C, Pomerantz JH. Human ARF Specifically Inhibits Epimorphic Regeneration in the Zebrafish Heart. Genes 2020. PMID: 32570883


  26. Emilie Barruet, Steven Garcia, Stanley Tamaki, Blanca M Morales, Jake Wu, Tania Moody, Jason H Pomerantz, Edward Chiaming Hsiao. MON-710 ACVR1 Activation in Primary and iPS-Derived Human Skeletal Muscle Stem Cells Impairs Myogenic Transcriptional Signature and Function. Journal of the Endocrine Society 2020. PMID:


  27. Barruet E, Garcia SM, Striedinger K, Wu J, Lee S, Byrnes L, Wong A, Xuefeng S, Tamaki S, Brack AS, Pomerantz JH. Functionally heterogeneous human satellite cells identified by single cell RNA sequencing. eLife 2020. PMID: 32234209


  28. Trentesaux C, Striedinger K, Pomerantz JH, Klein OD. From gut to glutes: The critical role of niche signals in the maintenance and renewal of adult stem cells. Current opinion in cell biology 2020. PMID: 32036295


  29. Balkin DM, Poranki M, Forester CM, Dorsey MJ, Slavotinek A, Pomerantz JH. TASP1 mutation in a female with craniofacial anomalies, anterior segment dysgenesis, congenital immunodeficiency and macrocytic anemia. Molecular genetics & genomic medicine 2019. PMID: 31350873


  30. Nguyen AB, Grimes B, Neuhaus J, Pomerantz JH. A Cross-sectional Study of the Association between Homelessness and Facial Fractures. Plastic and reconstructive surgery. Global open 2019. PMID: 31624672


  31. Ko J, Pomerantz JH, Perry H, Shieh JT, Slavotinek AM, Oberoi S, Klein OD. Case Report of Floating-Harbor Syndrome With Bilateral Cleft Lip. The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 2019. PMID: 31248274


  32. Wong A, Pomerantz JH. The Role of Muscle Stem Cells in Regeneration and Recovery after Denervation: A Review. Plastic and reconstructive surgery 2019. PMID: 30817650


  33. Davies MR, Garcia S, Tamaki S, Liu X, Lee S, Jose A, Pomerantz JH, Feeley BT. Muscle stem cell activation in a mouse model of rotator cuff injury. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2018. PMID: 28786534


  34. Garcia SM, Tamaki S, Lee S, Wong A, Jose A, Dreux J, Kouklis G, Sbitany H, Seth R, Knott PD, Heaton C, Ryan WR, Kim EA, Hansen SL, Hoffman WY, Pomerantz JH. High-Yield Purification, Preservation, and Serial Transplantation of Human Satellite Cells. Stem cell reports 2018. PMID: 29478895


  35. Cho GJ, Wang F, Garcia SM, Viner J, Hoffman WY, McDermott MW, Pomerantz JH. Recalcitrant Invasive Skin Cancer of the Scalp: Combined Extirpation and Microsurgical Reconstruction Without Cranioplasty. The Journal of craniofacial surgery 2017. PMID: 28045814


  36. Niethamer TK, Larson AR, O'Neill AK, Bershteyn M, Hsiao EC, Klein OD, Pomerantz JH, Bush JO. EPHRIN-B1 Mosaicism Drives Cell Segregation in Craniofrontonasal Syndrome hiPSC-Derived Neuroepithelial Cells. Stem cell reports 2017. PMID: 28238796


  37. Garcia SM, Tamaki S, Xu X, Pomerantz JH. Human Satellite Cell Isolation and Xenotransplantation. Methods in molecular biology (Clifton, N.J.) 2017. PMID: 28842905


  38. Hesse RG, Kouklis GK, Ahituv N, Pomerantz JH. The human ARF tumor suppressor senses blastema activity and suppresses epimorphic tissue regeneration. eLife 2015. PMID: 26575287


  39. Xu X, Wilschut KJ, Kouklis G, Tian H, Hesse R, Garland C, Sbitany H, Hansen S, Seth R, Knott PD, Hoffman WY, Pomerantz JH. Human Satellite Cell Transplantation and Regeneration from Diverse Skeletal Muscles. Stem cell reports 2015. PMID: 26352798


  40. Balkin DM, Chen I, Oberoi S, Pomerantz JH. Bilateral Coronoidectomy by Craniofacial Approach for Hecht Syndrome-Related Trismus. The Journal of craniofacial surgery 2015. PMID: 26335328


  41. Xiaoti Xu, Karlijn Wilschut, Gayle Kouklis, Hua Tian, Robert Hesse, Jason H. Pomerantz. Abstract 143. Plastic & Reconstructive Surgery 2015. PMID:


  42. Tamaki S, Nye C, Slorach E, Scharp D, Blau HM, Whiteley PE, Pomerantz JH. Simultaneous silencing of multiple RB and p53 pathway members induces cell cycle reentry in intact human pancreatic islets. BMC biotechnology 2014. PMID: 25305068


  43. Pomerantz JH, Blau HM. Tumor suppressors: enhancers or suppressors of regeneration? Development (Cambridge, England) 2013. PMID: 23715544


  44. Garland CB, Pomerantz JH. Regenerative strategies for craniofacial disorders. Frontiers in physiology 2012. PMID: 23248598


  45. Blau HM, Pomerantz JH. Re"evolutionary" regenerative medicine. JAMA 2010. PMID: 21177496


  46. Sacco A, Mourkioti F, Tran R, Choi J, Llewellyn M, Kraft P, Shkreli M, Delp S, Pomerantz JH, Artandi SE, Blau HM. Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice. Cell 2010. PMID: 21145579


  47. Pajcini KV, Corbel SY, Sage J, Pomerantz JH, Blau HM. Transient inactivation of Rb and ARF yields regenerative cells from postmitotic mammalian muscle. Cell stem cell 2010. PMID: 20682446


  48. Pomerantz JH, Mukherjee S, Palermo AT, Blau HM. Reprogramming to a muscle fate by fusion recapitulates differentiation. Journal of cell science 2009. PMID: 19295131


  49. Palermo A, Doyonnas R, Bhutani N, Pomerantz J, Alkan O, Blau HM. Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009. PMID: 19141533


  50. Kostin V. Pajcini, Jason H. Pomerantz, Ozan Alkan, Regis Doyonnas, Helen M. Blau. Myoblasts and macrophages share molecular components that contribute to cell-cell fusion. Journal of Experimental Medicine 2008. PMID:


  51. Gruber RP, Weintraub J, Pomerantz J. Suture techniques for the nasal tip. Aesthetic surgery journal 2008. PMID: 19083512


  52. Wan DC, Pomerantz JH, Brunet LJ, Kim JB, Chou YF, Wu BM, Harland R, Blau HM, Longaker MT. Noggin suppression enhances in vitro osteogenesis and accelerates in vivo bone formation. The Journal of biological chemistry 2007. PMID: 17609215


  53. Zhang F, Pomerantz JH, Sen G, Palermo AT, Blau HM. Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons. Proceedings of the National Academy of Sciences of the United States of America 2007. PMID: 17360535


  54. Wehrman TS, Raab WJ, Casipit CL, Doyonnas R, Pomerantz JH, Blau HM. A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions. Proceedings of the National Academy of Sciences of the United States of America 2006. PMID: 17148612


  55. Pomerantz JH and Blau HM (published as "APA Pomerantz, Jason MD; Pomerantz, Blau J."). 49: Plastic Surgery Research Council 2005 Clifford C. Synder, MD Award - Nuclear Cloning by Fusion of Somatic Cells Plastic and Reconstructive Surgery. 2006. PMID:


  56. Derrick C. Wan, Jason Pomerantz, Randall Nacamuli, Matthew Siedhoff, Helen Blau, Michael T. Longaker. Noggin suppression enhances osteogenesis of murine osteoblasts. Journal of the American College of Surgeons 2005. PMID:


  57. Derrick Wan, Jason H. Pomerantz, Randall P. Nacamuli, Michael T. Longaker. PSEF 2005 Scientific Essay Contest D. Ralph Millard, MD Investigator Award, First Place: siRNA Mediated Noggin Suppression Enhances Osteoblast Differentiation and Mineral Deposition. Plastic & Reconstructive Surgery 2005. PMID:


  58. Palermo AT, Labarge MA, Doyonnas R, Pomerantz J, Blau HM. Bone marrow contribution to skeletal muscle: a physiological response to stress. Developmental biology 2005. PMID: 15733662


  59. Pomerantz J, Blau HM. Nuclear reprogramming: a key to stem cell function in regenerative medicine. Nature cell biology 2004. PMID: 15340448


  60. Blau H and Pomerantz J.. Adult Bone-Marrow-Derived Stem Cells. From Brain to Brawn Differentiation. 2004. PMID:


  61. Blau HM, Doyonnas R, Labarge MA, Sacco A, Palermo A, and Pomerantz J.. Muscle injury: Blood to the rescue Experimental Hematology. 2004. PMID:


  62. Pomerantz J and Blau HM.. Reprogramming Mechanisms: Inducing the myogenic program in non-muscle cells Differentiation. 2004. PMID:


  63. Chin L, Tam A, Pomerantz J, Wong M, Holash J, Bardeesy N, Shen Q, O'Hagan R, Pantginis J, Zhou H, Horner JW, Cordon-Cardo C, Yancopoulos GD, DePinho RA. Essential role for oncogenic Ras in tumour maintenance. Nature 1999. PMID: 10440378


  64. Orlow I, Rabbani F, Chin L, Pomerantz J, Ligeois N, Dudas M, Depinho R, Cordón-Cardó C. Involvement of the Ink4a gene (p16 and p19arf) in murine tumorigenesis. International journal of oncology 1999. PMID: 10375589


  65. Chin L, Pomerantz J, DePinho RA. The INK4a/ARF tumor suppressor: one gene--two products--two pathways. Trends in biochemical sciences 1998. PMID: 9757829


  66. Pomerantz J, Schreiber-Agus N, Liégeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 1998. PMID: 9529248


  67. Chin L, Pomerantz J, Wong M, Horner J, and DePinho R.. The familial melanoma gene INK4a, cooperates with activated RAS in development of melanoma: A mouse model Journal of Dermatological Science. 1998. PMID:


  68. Chin L, Pomerantz J, Polsky D, Jacobson M, Cohen C, Cordon-Cardo C, Horner JW, DePinho RA. Cooperative effects of INK4a and ras in melanoma susceptibility in vivo. Genes & development 1997. PMID: 9353252


  69. Chin L, Pomerantz J, Liegeois N, Jacobson M, Horner J, and DePinho R.. Mouse Models to examine the role of INK4a and RAS in malignant melanoma Journal Investigative Dermatology. 1997. PMID: