Angela Rivers, MD, PhD

Publications
  1. An Analysis of Racial and Ethnic Backgrounds Within the CASiRe International Cohort of Sickle Cell Disease Patients: Implications for Disease Phenotype and Clinical Research.
  2. A study of the geographic distribution and associated risk factors of leg ulcers within an international cohort of sickle cell disease patients: the CASiRe group analysis.
  3. Potential role of LSD1 inhibitors in the treatment of sickle cell disease: a review of preclinical animal model data.
  4. Pharmacological inhibition of LSD1 and mTOR reduces mitochondrial retention and associated ROS levels in the red blood cells of sickle cell disease.
  5. Adverse Reactions to Pneumococcal Vaccine in Pediatric and Adolescent Patients with Sickle Cell Disease.
  6. RN-1, a potent and selective lysine-specific demethylase 1 inhibitor, increases γ-globin expression, F reticulocytes, and F cells in a sickle cell disease mouse model.
  7. Rationally designed capsid and transgene cassette of AAV6 vectors for dendritic cell-based cancer immunotherapy.
  8. Optimizing the transduction efficiency of capsid-modified AAV6 serotype vectors in primary human hematopoietic stem cells in vitro and in a xenograft mouse model in vivo.
  9. Drug-loaded sickle cells programmed ex vivo for delayed hemolysis target hypoxic tumor microvessels and augment tumor drug delivery.
  10. Optimization of the capsid of recombinant adeno-associated virus 2 (AAV2) vectors: the final threshold?
  11. High-efficiency transduction of human monocyte-derived dendritic cells by capsid-modified recombinant AAV2 vectors.
  12. Optimized adeno-associated virus (AAV)-protein phosphatase-5 helper viruses for efficient liver transduction by single-stranded AAV vectors: therapeutic expression of factor IX at reduced vector doses.
  13. Congenital cytopenias and bone marrow failure syndromes.
  14. Type 2B von Willebrand disease associated with the release of platelet agglutinates from megakaryocytes in the bone marrow.
  15. Optimization of recombinant adeno-associated viral vectors for human beta-globin gene transfer and transgene expression.