Devan Jaganath, MD, MPH

I am a pediatric infectious diseases physician, and my research program is focused on improving the care of children with tuberculosis (TB). In particular, I utilize epidemiology and data science methods to develop and identify new tools and biomarkers for TB diagnosis and treatment, and evaluate their accuracy and implementation through multi-center clinical studies.
Education
MPH, - , Johns Hopkins Bloomberg School of Public Health
Pediatrics, - , Johns Hopkins Hospital
MD, - , University of California, Los Angeles
Pediatric Infectious Diseases, - , University of California, San Francisco
BA, - , University of Pennsylvania

  1. Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant'Anna CC, Sharma S, Starke JR, Triasih R, Achar J, Amanullah F, Armitage LY, Aurilio RB, Buck WC, Centis R, Chabala C, Cruz AT, Demers AM, du Preez K, Enimil A, Furin J, Garcia-Prats AJ, Gonzalez NE, Hoddinott G, Isaakidis P, Jaganath D, Kabra SK, Kampmann B, Kay A, Kitai I, Lopez-Varela E, Maleche-Obimbo E, Malaspina FM, Velásquez JN, Nuttall JJC, Oliwa JN, Andrade IO, Perez-Velez CM, Rabie H, Seddon JA, Sekadde MP, Shen A, Skrahina A, Soriano-Arandes A, Steenhoff AP, Tebruegge M, Tovar MA, Tsogt B, van der Zalm MM, Welch H, Migliori GB. Clinical standards for drug-susceptible TB in children and adolescents. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023. PMID: 37491754



  2. Huddart S, Asege L, Jaganath D, Golla M, Dang H, Lovelina L, Derendinger B, Andama A, Christopher DJ, Nhung NV, Theron G, Denkinger CM, Nahid P, Cattamanchi A, Yu C. Continuous cough monitoring: a novel digital biomarker for TB diagnosis and treatment response monitoring. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023. PMID: 36855045




  3. Jaganath D, Reza TF, Wambi P, Nakafeero J, Kiconco E, Nanyonga G, Oumo EA, Nsereko MC, Sekadde MP, Nabukenya-Mudiope MG, Kato-Maeda M, Andama A, Yoon C, Mohanty S, Wobudeya E, Cattamanchi A. The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children. 2022. PMID: 35451001


  4. Zimmer AJ, Ugarte-Gil C, Pathri R, Dewan P, Jaganath D, Cattamanchi A, Pai M, Grandjean Lapierre S. Making cough count in tuberculosis care. Communications medicine 2022. PMID: 35814294


  5. Andama A, Whitman GR, Crowder R, Reza TF, Jaganath D, Mulondo J, Nalugwa TK, Semitala FC, Worodria W, Cook C, Wood RC, Weigel KM, Olson AM, Lohmiller Shaw J, Kato-Maeda M, Denkinger CM, Nahid P, Cangelosi GA, Cattamanchi A. Accuracy of Tongue Swab Testing Using Xpert MTB-RIF Ultra for Tuberculosis Diagnosis. Journal of clinical microbiology 2022. PMID: 35758702



  6. Jaganath D, Beaudry J, Salazar-Austin N. Tuberculosis in Children. 2022. PMID: 35168714


  7. Willis CN, Larson SR, Andama A, Jaganath D, Misra M, Cattamanchi A, Mohanty SK. Engineered Electroactive Solutions for Electrochemical Detection of Tuberculosis-Associated Volatile Organic Biomarkers. IEEE sensors journal 2021. PMID: 36157103


  8. Chitnis AS, Jaganath D, Gish RG, Wong RJ. Diagnosis and Treatment of Latent Tuberculosis Infection. The American journal of gastroenterology 2021. PMID: 34382949


  9. Magni R, Rruga F, Alsaab FM, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A. Author Correction: Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes. Scientific Reports 2021. PMID: 34580341


  10. Fossati A, Richards AL, Chen KH, Jaganath D, Cattamanchi A, Ernst JD, Swaney DL. Toward Comprehensive Plasma Proteomics by Orthogonal Protease Digestion. Journal of proteome research 2021. PMID: 34319755


  11. Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M, Sekadde MP, Mudiope M, Kato-Maeda M, Starke J, Andama A, Mohanty S, Wobudeya E, Cattamanchi A. A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda. Journal of the Pediatric Infectious Diseases Society 2021. PMID: 33416072


  12. Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mukwatamundu J, Mwebe S, Semitala CF, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A. The transition to Xpert MTB/RIF ultra: diagnostic accuracy for pulmonary tuberculosis in Kampala, Uganda. BMC infectious diseases 2021. PMID: 33430790


  13. Magni R, Rruga F, Alsaab F, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A. Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes. Scientific Reports 2020. PMID: 32811861


  14. Jaganath D, Rajan J, Yoon C, Ravindran R, Andama A, Asege L, Mwebe SZ, Katende J, Nakaye M, Semitala FC, Khan IH, Cattamanchi A. Evaluation of multi-antigen serological screening for active tuberculosis among people living with HIV. PloS one 2020. PMID: 32497095


  15. Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mwebe S, Semitala F, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A. Accuracy and incremental yield of urine Xpert MTB/RIF Ultra versus Determine TB-LAM for diagnosis of pulmonary tuberculosis. Diagnostic microbiology and infectious disease 2019. PMID: 31727376


  16. Wobudeya E, Jaganath D, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Outcomes of empiric treatment for pediatric tuberculosis, Kampala, Uganda, 2010-2015. BMC public health 2019. PMID: 31035984


  17. Jaganath D, Wobudeya E, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Seasonality of childhood tuberculosis cases in Kampala, Uganda, 2010-2015. PloS one 2019. PMID: 30964908


  18. Jaganath D, Johnson K, Tschudy MM, Topel K, Stackhouse B, Solomon BS. Desirability of Clinic-Based Financial Services in Urban Pediatric Primary Care. The Journal of pediatrics 2018. PMID: 30029865


  19. Quinn C, Johnson K, Raney C, Baker J, Topel K, Tschudy MM, Jaganath D, Solomon BS. "In the Clinic They Know Us": Preferences for Clinic-Based Financial and Employment Services in Urban Pediatric Primary Care. Academic pediatrics 2018. PMID: 29959085


  20. Jaganath D, Jorakate P, Makprasert S, Sangwichian O, Akarachotpong T, Thamthitiwat S, Khemla S, DeFries T, Baggett HC, Whistler T, Gregory CJ, Rhodes J. Staphylococcus aureus Bacteremia Incidence and Methicillin Resistance in Rural Thailand, 2006-2014. The American journal of tropical medicine and hygiene 2018. PMID: 29761760




  21. Grajeda LM, Ivanescu A, Saito M, Crainiceanu C, Jaganath D, Gilman RH, Crabtree JE, Kelleher D, Cabrera L, Cama V, Checkley W. Modelling subject-specific childhood growth using linear mixed-effect models with cubic regression splines. Emerging themes in epidemiology 2016. PMID: 26752996


  22. Gaviola C, Miele CH, Wise RA, Gilman RH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Hansel NN, Checkley W, CRONICAS Cohort Study Group. Urbanisation but not biomass fuel smoke exposure is associated with asthma prevalence in four resource-limited settings. Thorax 2015. PMID: 26699762


  23. Miele CH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Gilman RH, Johnson CM, Diette GB, Wise RA, Checkley W, CRONICAS Cohort Study Group. Urbanization and Daily Exposure to Biomass Fuel Smoke Both Contribute to Chronic Bronchitis Risk in a Population with Low Prevalence of Daily Tobacco Smoking. COPD 2015. PMID: 26552585


  24. Wampande EM, Mupere E, Jaganath D, Nsereko M, Mayanja HK, Eisenach K, Boom WH, Gagneux S, Joloba ML, Tuberculosis Research Unit. Distribution and transmission of Mycobacterium tuberculosis complex lineages among children in peri-urban Kampala, Uganda. BMC pediatrics 2015. PMID: 26424324


  25. Jaganath D, Miranda JJ, Gilman RH, Wise RA, Diette GB, Miele CH, Bernabe-Ortiz A, Checkley W, CRONICAS Cohort Study Group. Prevalence of chronic obstructive pulmonary disease and variation in risk factors across four geographically diverse resource-limited settings in Peru. Respiratory research 2015. PMID: 25889777


  26. Jaganath D, Khatry SK, Murray-Kolb LE, LeClerq SC, Christian P. The role of pre-primary classes on school-age cognition in rural Nepal. The Journal of pediatrics 2014. PMID: 25557964


  27. Checkley W, White AC, Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA, Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, Xiao L, Zhu G, Houpt ER. A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium. The Lancet. Infectious diseases 2014. PMID: 25278220


  28. Bearnot B, Coria A, Barnett BS, Clark EH, Gartland MG, Jaganath D, Mendenhall E, Seu L, Worjoloh AG, Carothers CL, Vermund SH, Heimburger DC. Global health research in narrative: a qualitative look at the FICRS-F experience. The American journal of tropical medicine and hygiene 2014. PMID: 25246694



  29. Jaganath D, Saito M, Gilman RH, Queiroz DM, Rocha GA, Cama V, Cabrera L, Kelleher D, Windle HJ, Crabtree JE, Checkley W. First detected Helicobacter pylori infection in infancy modifies the association between diarrheal disease and childhood growth in Peru. Helicobacter 2014. PMID: 24750275


  30. Jaganath D, Walker AS, Ssali F, Musiime V, Kiweewa F, Kityo C, Salata R, Mugyenyi P, DART Trial , ARROW Trial. HIV-associated anemia after 96 weeks on therapy: determinants across age ranges in Uganda and Zimbabwe. AIDS research and human retroviruses 2014. PMID: 24506102


  31. Jaganath D, Zalwango S, Okware B, Nsereko M, Kisingo H, Malone L, Lancioni C, Okwera A, Joloba M, Mayanja-Kizza H, Boom WH, Stein C, Mupere E, Tuberculosis Research Unit. Contact investigation for active tuberculosis among child contacts in Uganda. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013. PMID: 24077055



  32. Young SD, Cumberland WG, Lee SJ, Jaganath D, Szekeres G, Coates T. Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial. Annals of internal medicine 2013. PMID: 24026317






  33. Vecsey CG, Peixoto L, Choi JH, Wimmer M, Jaganath D, Hernandez PJ, Blackwell J, Meda K, Park AJ, Hannenhalli S, Abel T. Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus. Physiological genomics 2012. PMID: 22930738




  34. Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, Abel T. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature 2009. PMID: 19847264