Devan Jaganath, MD, MPH

I am a pediatric infectious diseases physician, and my research program is focused on improving the care of children with tuberculosis (TB). In particular, I utilize epidemiology and data science methods to develop and identify new tools and biomarkers for TB diagnosis and treatment, and evaluate their accuracy and implementation through multi-center clinical studies.
Education
MPH, - , Johns Hopkins Bloomberg School of Public Health
Pediatrics, - , Johns Hopkins Hospital
MD, - , University of California, Los Angeles
Pediatric Infectious Diseases, - , University of California, San Francisco
BA, - , University of Pennsylvania

  1. Jaganath D, Nabeta P, Nicol MP, Castro R, Wambi P, Zar HJ, Workman L, Lodha R, Singh UB, Bavdekar A, Sanghavi S, Trollip A, Mace A, Bonnet M, Lounnas M, de Haas P, Tiemersma E, Alland D, Banada P, Cattamanchi A, Ruhwald M, Wobudeya E, Denkinger CM. Stool processing methods for Xpert Ultra testing in childhood tuberculosis: A prospective, multi-country accuracy study. medRxiv : the preprint server for health sciences 2024. PMID: 39763536


  2. Fossati A, Wambi P, Jaganath D, Calderon R, Castro R, Mohapatra A, McKetney J, Luiz J, Nerurkar R, Nkereuwem E, Franke MF, Mousavian Z, Collins JM, Sigal GB, Segal MR, Kampman B, Wobudeya E, Cattamanchi A, Ernst JD, Zar HJ, Swaney DL, COMBO Study. Plasma proteomics for novel biomarker discovery in childhood tuberculosis. medRxiv : the preprint server for health sciences 2024. PMID: 39677468


  3. Wambi P, West NS, Nabugoomu J, Kityamuwesi A, Crowder R, Kunihira L, Wobudeya E, Cattamanchi A, Jaganath D, Katamba A. A mixed methods evaluation of 99DOTS digital adherence technology uptake among adolescents treated for pulmonary tuberculosis in Uganda. medRxiv : the preprint server for health sciences 2024. PMID: 39677470


  4. Huddart S, Yadav V, Sieberts SK, Omberg L, Raberahona M, Rakotoarivelo R, Lyimo IN, Lweno O, Christopher DJ, Nhung NV, Theron G, Worodria W, Yu CY, Bachman CM, Burkot S, Dewan P, Kulhare S, Small PM, Cattamanchi A, Jaganath D, Grandjean Lapierre S. A dataset of Solicited Cough Sound for Tuberculosis Triage Testing. Scientific data 2024. PMID: 39424635


  5. Wick JM, Ni Y, Halmer N, Wong RJ, Chitnis AS, Jaganath D, Krueger AL, Skarbinski J. Tuberculosis and Chronic Hepatitis B Virus Infection Screening Among Non-US-Born Persons in an Integrated Health System in California. Open forum infectious diseases 2024. PMID: 39296340


  6. Marusinec R, Clifton T, Chitnis AS, Jaganath D. Advanced pulmonary tuberculosis in Alameda County: Ten-year incidence and risk factors. Journal of clinical tuberculosis and other mycobacterial diseases 2024. PMID: 39224114


  7. Bertumen JB, Pascopella L, Han E, Glenn-Finer R, Wong RJ, Chitnis A, Jaganath D, Jewell MP, Gounder P, McElroy S, Stockman L, Barry P. Expected vs Reported Chronic Hepatitis B Infection Cases in Persons with Active Tuberculosis - California, 2016-2020. Journal of public health management and practice : JPHMP 2024. PMID: 38985652


  8. Bertumen JB, Pascopella L, Han E, Glenn-Finer R, Wong RJ, Chitnis A, Jaganath D, Jewell M, Gounder P, McElroy S, Stockman L, Barry P. Epidemiology and Treatment Outcomes of Tuberculosis with Chronic Hepatitis B Infection-California, 2016-2020. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2024. PMID: 38531668


  9. Bijker EM, Horn L, LaCourse S, MacLean EL, Marais BJ, Nicol MP, Olbrich L, Seddon JA, Sutherland JS, Song R, Zar HJ, Jaganath D, Child TB Diagnostics Consensus Group. The inclusion of children and adolescents in tuberculosis diagnostic development and evaluation-a consensus statement. The Lancet. Infectious diseases 2024. PMID: 38971177


  10. Worodria W, Castro R, Kik SV, Dalay V, Derendinger B, Festo C, Nguyen TQ, Raberahona M, Sudarsan S, Andama A, Thangakunam B, Lyimo I, Nguyen VN, Rakotoarivelo R, Theron G, Yu C, Denkinger CM, Lapierre SG, Cattamanchi A, Christopher DJ, Jaganath D, R2D2 TB Network. An independent, multi-country head-to-head accuracy comparison of automated chest x-ray algorithms for the triage of pulmonary tuberculosis. medRxiv : the preprint server for health sciences 2024. PMID: 38946949


  11. Jeppson MA, Rasmussen Z, Castro R, Nalugwa T, Kisakye E, Mangeni W, Andama A, Jaganath D, Cattamanchi A, Mohanty SK. Integration of Electrochemical Sensing and Machine Learning to Detect Tuberculosis via Methyl Nicotinate in Patient Breath. medRxiv : the preprint server for health sciences 2024. PMID: 38826389


  12. Huddart S, Yadav V, Sieberts SK, Omberg L, Raberahona M, Rakotoarivelo R, Lyimo IN, Lweno O, Christopher DJ, Nhung NV, Theron G, Worodria W, Yu CY, Bachman CM, Burkot S, Dewan P, Kulhare S, Small PM, Cattamanchi A, Jaganath D, Lapierre SG. Solicited Cough Sound Analysis for Tuberculosis Triage Testing: The CODA TB DREAM Challenge Dataset. medRxiv : the preprint server for health sciences 2024. PMID: 38585855


  13. Shah K, Nakafeero J, Kadota JL, Wambi P, Nanyonga G, Kiconco E, Deus A, Sekadde MP, Nabukenya-Mudiope MG, Tukamuhebwa HA, Mupere E, Mohanty S, Cattamanchi A, Wobudeya E, Shete PB, Jaganath D. The socioeconomic burden of pediatric tuberculosis and role of child-sensitive social protection. BMC public health 2023. PMID: 38007477


  14. Suliman S, Jaganath D, DiNardo A. Predicting pediatric TB: the need for age-specific host biosignatures. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2023. PMID: 37144361


  15. Chiang SS, Graham SM, Schaaf HS, Marais BJ, Sant'Anna CC, Sharma S, Starke JR, Triasih R, Achar J, Amanullah F, Armitage LY, Aurilio RB, Buck WC, Centis R, Chabala C, Cruz AT, Demers AM, du Preez K, Enimil A, Furin J, Garcia-Prats AJ, Gonzalez NE, Hoddinott G, Isaakidis P, Jaganath D, Kabra SK, Kampmann B, Kay A, Kitai I, Lopez-Varela E, Maleche-Obimbo E, Malaspina FM, Velásquez JN, Nuttall JJC, Oliwa JN, Andrade IO, Perez-Velez CM, Rabie H, Seddon JA, Sekadde MP, Shen A, Skrahina A, Soriano-Arandes A, Steenhoff AP, Tebruegge M, Tovar MA, Tsogt B, van der Zalm MM, Welch H, Migliori GB. Clinical standards for drug-susceptible TB in children and adolescents. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023. PMID: 37491754


  16. Chen J, Marusinec R, Brown R, Shiau R, Jaganath D, Chitnis AS. Epidemiology of Culture-Negative Pulmonary Tuberculosis-Alameda County, 2010-2019. Journal of public health management and practice : JPHMP 2023. PMID: 36867649


  17. Huddart S, Asege L, Jaganath D, Golla M, Dang H, Lovelina L, Derendinger B, Andama A, Christopher DJ, Nhung NV, Theron G, Denkinger CM, Nahid P, Cattamanchi A, Yu C. Continuous cough monitoring: a novel digital biomarker for TB diagnosis and treatment response monitoring. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2023. PMID: 36855045


  18. Leddy AM, Jaganath D, Triasih R, Wobudeya E, Bellotti de Oliveira MC, Sheremeta Y, Becerra MC, Chiang SS. Social Determinants of Adherence to Treatment for Tuberculosis Infection and Disease Among Children, Adolescents, and Young Adults: A Narrative Review. Journal of the Pediatric Infectious Diseases Society 2022. PMID: 36314549


  19. Wu IL, Chen J, Shiau R, Chitnis AS, Jaganath D. Tuberculosis Disease Among Adults Aged 65 Years and Older: Alameda County, California, 2016-2019. Open forum infectious diseases 2022. PMID: 36438617


  20. Jaganath D, Reza TF, Wambi P, Nakafeero J, Kiconco E, Nanyonga G, Oumo EA, Nsereko MC, Sekadde MP, Nabukenya-Mudiope MG, Kato-Maeda M, Andama A, Yoon C, Mohanty S, Wobudeya E, Cattamanchi A. The Role of C-Reactive Protein as a Triage Tool for Pulmonary Tuberculosis in Children. 2022. PMID: 35451001


  21. Zimmer AJ, Ugarte-Gil C, Pathri R, Dewan P, Jaganath D, Cattamanchi A, Pai M, Grandjean Lapierre S. Making cough count in tuberculosis care. Communications medicine 2022. PMID: 35814294


  22. Andama A, Whitman GR, Crowder R, Reza TF, Jaganath D, Mulondo J, Nalugwa TK, Semitala FC, Worodria W, Cook C, Wood RC, Weigel KM, Olson AM, Lohmiller Shaw J, Kato-Maeda M, Denkinger CM, Nahid P, Cangelosi GA, Cattamanchi A. Accuracy of Tongue Swab Testing Using Xpert MTB-RIF Ultra for Tuberculosis Diagnosis. Journal of clinical microbiology 2022. PMID: 35758702


  23. Wu IL, Chitnis AS, Jaganath D. A narrative review of tuberculosis in the United States among persons aged 65 years and older. Journal of clinical tuberculosis and other mycobacterial diseases 2022. PMID: 35757390


  24. Jaganath D, Beaudry J, Salazar-Austin N. Tuberculosis in Children. 2022. PMID: 35168714


  25. Willis CN, Larson SR, Andama A, Jaganath D, Misra M, Cattamanchi A, Mohanty SK. Engineered Electroactive Solutions for Electrochemical Detection of Tuberculosis-Associated Volatile Organic Biomarkers. IEEE sensors journal 2021. PMID: 36157103


  26. Chitnis AS, Jaganath D, Gish RG, Wong RJ. Diagnosis and Treatment of Latent Tuberculosis Infection. The American journal of gastroenterology 2021. PMID: 34382949


  27. Magni R, Rruga F, Alsaab FM, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A. Author Correction: Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes. Scientific Reports 2021. PMID: 34580341


  28. Fossati A, Richards AL, Chen KH, Jaganath D, Cattamanchi A, Ernst JD, Swaney DL. Toward Comprehensive Plasma Proteomics by Orthogonal Protease Digestion. Journal of proteome research 2021. PMID: 34319755


  29. Jaganath D, Wambi P, Reza TF, Nakafeero J, Aben EO, Kiconco E, Nannyonga G, Nsereko M, Sekadde MP, Mudiope M, Kato-Maeda M, Starke J, Andama A, Mohanty S, Wobudeya E, Cattamanchi A. A Prospective Evaluation of Xpert MTB/RIF Ultra for Childhood Pulmonary Tuberculosis in Uganda. Journal of the Pediatric Infectious Diseases Society 2021. PMID: 33416072


  30. Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mukwatamundu J, Mwebe S, Semitala CF, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A. The transition to Xpert MTB/RIF ultra: diagnostic accuracy for pulmonary tuberculosis in Kampala, Uganda. BMC infectious diseases 2021. PMID: 33430790


  31. Magni R, Rruga F, Alsaab F, Sharif S, Howard M, Espina V, Kim B, Lepene B, Lee G, Alayouni MA, Steinberg H, Araujo R, Kashanchi F, Riccardi F, Morreira S, Araujo A, Poli F, Jaganath D, Semitala FC, Worodria W, Andama A, Choudhary A, Honnen WJ, Petricoin EF, Cattamanchi A, Colombatti R, de Waard JH, Oberhelman R, Pinter A, Gilman RH, Liotta LA, Luchini A. Lipoarabinomannan antigenic epitope differences in tuberculosis disease subtypes. Scientific Reports 2020. PMID: 32811861


  32. Jaganath D, Rajan J, Yoon C, Ravindran R, Andama A, Asege L, Mwebe SZ, Katende J, Nakaye M, Semitala FC, Khan IH, Cattamanchi A. Evaluation of multi-antigen serological screening for active tuberculosis among people living with HIV. PloS one 2020. PMID: 32497095


  33. Andama A, Jaganath D, Crowder R, Asege L, Nakaye M, Katumba D, Mwebe S, Semitala F, Worodria W, Joloba M, Mohanty S, Somoskovi A, Cattamanchi A. Accuracy and incremental yield of urine Xpert MTB/RIF Ultra versus Determine TB-LAM for diagnosis of pulmonary tuberculosis. Diagnostic microbiology and infectious disease 2019. PMID: 31727376


  34. Wobudeya E, Jaganath D, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Outcomes of empiric treatment for pediatric tuberculosis, Kampala, Uganda, 2010-2015. BMC public health 2019. PMID: 31035984


  35. Jaganath D, Wobudeya E, Sekadde MP, Nsangi B, Haq H, Cattamanchi A. Seasonality of childhood tuberculosis cases in Kampala, Uganda, 2010-2015. PloS one 2019. PMID: 30964908


  36. Jaganath D, Johnson K, Tschudy MM, Topel K, Stackhouse B, Solomon BS. Desirability of Clinic-Based Financial Services in Urban Pediatric Primary Care. The Journal of pediatrics 2018. PMID: 30029865


  37. Quinn C, Johnson K, Raney C, Baker J, Topel K, Tschudy MM, Jaganath D, Solomon BS. "In the Clinic They Know Us": Preferences for Clinic-Based Financial and Employment Services in Urban Pediatric Primary Care. Academic pediatrics 2018. PMID: 29959085


  38. Jaganath D, Jorakate P, Makprasert S, Sangwichian O, Akarachotpong T, Thamthitiwat S, Khemla S, DeFries T, Baggett HC, Whistler T, Gregory CJ, Rhodes J. Staphylococcus aureus Bacteremia Incidence and Methicillin Resistance in Rural Thailand, 2006-2014. The American journal of tropical medicine and hygiene 2018. PMID: 29761760


  39. Jaganath D, Schaaf HS, Donald PR. Revisiting the mutant prevention concentration to guide dosing in childhood tuberculosis. The Journal of antimicrobial chemotherapy 2017. PMID: 28333284


  40. Jaganath D, Lamichhane G, Shah M. Carbapenems against Mycobacterium tuberculosis: a review of the evidence. The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2016. PMID: 27776583


  41. Grajeda LM, Ivanescu A, Saito M, Crainiceanu C, Jaganath D, Gilman RH, Crabtree JE, Kelleher D, Cabrera L, Cama V, Checkley W. Modelling subject-specific childhood growth using linear mixed-effect models with cubic regression splines. Emerging themes in epidemiology 2016. PMID: 26752996


  42. Gaviola C, Miele CH, Wise RA, Gilman RH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Hansel NN, Checkley W, CRONICAS Cohort Study Group. Urbanisation but not biomass fuel smoke exposure is associated with asthma prevalence in four resource-limited settings. Thorax 2015. PMID: 26699762


  43. Miele CH, Jaganath D, Miranda JJ, Bernabe-Ortiz A, Gilman RH, Johnson CM, Diette GB, Wise RA, Checkley W, CRONICAS Cohort Study Group. Urbanization and Daily Exposure to Biomass Fuel Smoke Both Contribute to Chronic Bronchitis Risk in a Population with Low Prevalence of Daily Tobacco Smoking. COPD 2015. PMID: 26552585


  44. Wampande EM, Mupere E, Jaganath D, Nsereko M, Mayanja HK, Eisenach K, Boom WH, Gagneux S, Joloba ML, Tuberculosis Research Unit. Distribution and transmission of Mycobacterium tuberculosis complex lineages among children in peri-urban Kampala, Uganda. BMC pediatrics 2015. PMID: 26424324


  45. Jaganath D, Miranda JJ, Gilman RH, Wise RA, Diette GB, Miele CH, Bernabe-Ortiz A, Checkley W, CRONICAS Cohort Study Group. Prevalence of chronic obstructive pulmonary disease and variation in risk factors across four geographically diverse resource-limited settings in Peru. Respiratory research 2015. PMID: 25889777


  46. Jaganath D, Khatry SK, Murray-Kolb LE, LeClerq SC, Christian P. The role of pre-primary classes on school-age cognition in rural Nepal. The Journal of pediatrics 2014. PMID: 25557964


  47. Checkley W, White AC, Jaganath D, Arrowood MJ, Chalmers RM, Chen XM, Fayer R, Griffiths JK, Guerrant RL, Hedstrom L, Huston CD, Kotloff KL, Kang G, Mead JR, Miller M, Petri WA, Priest JW, Roos DS, Striepen B, Thompson RC, Ward HD, Van Voorhis WA, Xiao L, Zhu G, Houpt ER. A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium. The Lancet. Infectious diseases 2014. PMID: 25278220


  48. Bearnot B, Coria A, Barnett BS, Clark EH, Gartland MG, Jaganath D, Mendenhall E, Seu L, Worjoloh AG, Carothers CL, Vermund SH, Heimburger DC. Global health research in narrative: a qualitative look at the FICRS-F experience. The American journal of tropical medicine and hygiene 2014. PMID: 25246694


  49. Young SD, Holloway I, Jaganath D, Rice E, Westmoreland D, Coates T. Project HOPE: online social network changes in an HIV prevention randomized controlled trial for African American and Latino men who have sex with men. American journal of public health 2014. PMID: 25033137


  50. Jaganath D, Saito M, Gilman RH, Queiroz DM, Rocha GA, Cama V, Cabrera L, Kelleher D, Windle HJ, Crabtree JE, Checkley W. First detected Helicobacter pylori infection in infancy modifies the association between diarrheal disease and childhood growth in Peru. Helicobacter 2014. PMID: 24750275


  51. Jaganath D, Walker AS, Ssali F, Musiime V, Kiweewa F, Kityo C, Salata R, Mugyenyi P, DART Trial , ARROW Trial. HIV-associated anemia after 96 weeks on therapy: determinants across age ranges in Uganda and Zimbabwe. AIDS research and human retroviruses 2014. PMID: 24506102


  52. Jaganath D, Zalwango S, Okware B, Nsereko M, Kisingo H, Malone L, Lancioni C, Okwera A, Joloba M, Mayanja-Kizza H, Boom WH, Stein C, Mupere E, Tuberculosis Research Unit. Contact investigation for active tuberculosis among child contacts in Uganda. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2013. PMID: 24077055


  53. Jaganath D, Mulenga C, Hoffman RM, Hamilton J, Boneh G. This is My Story: participatory performance for HIV and AIDS education at the University of Malawi. Health education research 2013. PMID: 24047713


  54. Young SD, Cumberland WG, Lee SJ, Jaganath D, Szekeres G, Coates T. Social networking technologies as an emerging tool for HIV prevention: a cluster randomized trial. Annals of internal medicine 2013. PMID: 24026317


  55. Young SD, Harrell L, Jaganath D, Cohen AC, Shoptaw S. Feasibility of recruiting peer educators for an online social networking-based health intervention. Health education journal 2013. PMID: 25530624


  56. Young SD, Jaganath D. Feasibility of using social networking technologies for health research among men who have sex with men: a mixed methods study. American journal of men's health 2013. PMID: 23407600


  57. Young SD, Jaganath D. Online social networking for HIV education and prevention: a mixed-methods analysis. Sexually transmitted diseases 2013. PMID: 23324979


  58. Jaganath D, Mupere E. Childhood tuberculosis and malnutrition. The Journal of infectious diseases 2012. PMID: 23033147


  59. Vecsey CG, Peixoto L, Choi JH, Wimmer M, Jaganath D, Hernandez PJ, Blackwell J, Meda K, Park AJ, Hannenhalli S, Abel T. Genomic analysis of sleep deprivation reveals translational regulation in the hippocampus. Physiological genomics 2012. PMID: 22930738


  60. Jaganath D, Gill HK, Cohen AC, Young SD. Harnessing Online Peer Education (HOPE): integrating C-POL and social media to train peer leaders in HIV prevention. AIDS care 2011. PMID: 22149081


  61. Boneh G, Jaganath D. Performance as a component of HIV/AIDS education: Process and Collaboration for Empowerment and Discussion. American journal of public health 2011. PMID: 21233444


  62. Vecsey CG, Baillie GS, Jaganath D, Havekes R, Daniels A, Wimmer M, Huang T, Brown KM, Li XY, Descalzi G, Kim SS, Chen T, Shang YZ, Zhuo M, Houslay MD, Abel T. Sleep deprivation impairs cAMP signalling in the hippocampus. Nature 2009. PMID: 19847264