Yvonne Wu, MD, MPH

Dr. Yvonne Wu is a child neurologist and epidemiologist with expertise in newborn brain injury and cerebral palsy (CP). After obtaining a BS from Yale and an MD from Harvard Medical School, she completed her Child Neurology Residency training at University of California, San Francisco (UCSF) and obtained a MPH in Epidemiology at University of California, Berkeley. The goal of Dr. Wu's research is to develop new strategies to prevent CP. Her research has been funded by NIH, Thrasher Research Fund, CP Alliance, CP International Research Foundation and others. Dr. Wu has been the recipient of several teaching awards at UCSF. She is on the Editorial Boards of Pediatric Neurology and Journal of Child Neurology, and served as an elected Council Member for the Society for Pediatric Research. Dr. Wu has published over 77 papers, including in high impact journals such as JAMA, NEJM, and Pediatrics. She authors UpToDate chapters on hypoxic-ischemic encephalopathy, and has written several review chapters on perinatal stroke and cerebral palsy. Dr. Dr. Wu has studied erythropoietin as a novel neuroprotective therapy for newborn infants with hypoxic-ischemic brain injury. She was the PI of NEAT and NEAT O (Phase I and Phase II studies), and is currently the PI of a large NIH-funded multi-center Phase III clinical trial (HEAL) studying erythropoietin in this population (www.heal-trial.org).
Education
M.P.H., 2000 - Public Health, UC Berkeley
Pediatrics and Neurology Residencies, 1998 - School of Medicine, University of California, San Francisco
M.D., 1992 - School of Medicine, Harvard University
B. S., 1988 - Psychobiology, Yale
Websites

  1. Glass HC, Wood TR, Comstock BA, Numis AL, Bonifacio SL, Cornet MC, Gonzalez FF, Morell A, Kolnik SE, Li Y, Mathur A, Mietzsch U, Wu TW, Wusthoff CJ, Thoresen M, Heagerty PJ, Juul SE, Wu YW. Predictors of Death or Severe Impairment in Neonates With Hypoxic-Ischemic Encephalopathy. JAMA network open 2024. PMID: 39636636


  2. Cornet MC, Gonzalez FF, Glass HC, Wu TW, Wisnowski JL, Li Y, Heagerty P, Juul SE, Wu YW. Chorioamnionitis and Two-Year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2024. PMID: 39577760


  3. Chan NH, Hawkins CC, Rodrigues BV, Cornet MC, Gonzalez FF, Wu YW. Neuroprotection for neonatal hypoxic-ischemic encephalopathy: A review of novel therapies evaluated in clinical studies. Developmental medicine and child neurology 2024. PMID: 39563426


  4. Cornet MC, Numis AL, Monsell SE, Chan NH, Gonzalez FF, Comstock BA, Juul SE, Wusthoff CJ, Wu YW, Glass HC. Assessing Early Severity of Hypoxic-Ischemic Encephalopathy: The Role of Electroencephalogram Background in Addition to Sarnat Exam. The Journal of pediatrics 2024. PMID: 39557386


  5. Frymoyer A, Vasconcelos AG, Juul SE, Comstock BA, Heagerty PJ, Wu YW. On target dosing: erythropoietin exposure in neonates with hypoxic-ischemic encephalopathy in the HEAL trial. Pediatric research 2024. PMID: 39523391


  6. Cornet MC, Kuzniewicz MW, Scheffler AW, Gaw SL, Yeh P, Newman TB, Wu YW. Epidural Analgesia During Labor and Neonatal Hypoxic-Ischemic Encephalopathy. JAMA network open 2024. PMID: 39283635


  7. Lew CO, Calabrese E, Chen JV, Tang F, Chaudhari G, Lee A, Faro J, Juul S, Mathur A, McKinstry RC, Wisnowski JL, Rauschecker A, Wu YW, Li Y. Artificial Intelligence Outcome Prediction in Neonates with Encephalopathy (AI-OPiNE). Radiology. Artificial intelligence 2024. PMID: 38984984


  8. Gonzalez FF, Monsell SE, Cornet MC, Glass H, Wisnowski J, Mathur A, McKinstry R, Li Y, Wu TW, Mayock DE, Heagerty PJ, Juul SE, Wu YW. Perinatal arterial ischemic stroke diagnosed in infants receiving therapeutic hypothermia for hypoxic-ischemic encephalopathy. Pediatric research 2024. PMID: 39191951


  9. Mietzsch U, Kolnik SE, Wood TR, Natarajan N, Gonzalez FF, Glass H, Mayock DE, Bonifacio SL, Van Meurs K, Comstock BA, Heagerty PJ, Wu TW, Wu YW, Juul SE, HEAL Trial Study Group. Evolution of the Sarnat exam and association with 2-year outcomes in infants with moderate or severe hypoxic-ischaemic encephalopathy: a secondary analysis of the HEAL Trial. Archives of disease in childhood. Fetal and neonatal edition 2023. PMID: 38071538


  10. Cornet MC, Wu YW, Forquer H, Avalos LA, Sriram A, Scheffler AW, Newman TB, Kuzniewicz MW. Maternal treatment with selective serotonin reuptake inhibitors during pregnancy and delayed neonatal adaptation: a population-based cohort study. Archives of disease in childhood. Fetal and neonatal edition 2023. PMID: 38071585


  11. Wu YW, Wisnowski JL, Glass HC, Mathur AM, Li Y, Monsell SE, Juul SE, McKinstry RC. Correction: Advancing brain MRI as a prognostic indicator in hypoxic-ischemic encephalopathy. Pediatric research 2023. PMID: 38071279


  12. Kearney RE, Wu YW, Vargas-Calixto J, Kuzniewicz MW, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick PA. Construction of a comprehensive fetal monitoring database for the study of perinatal hypoxic ischemic encephalopathy. MethodsX 2024. PMID: 38524309


  13. Chen JV, Li Y, Tang F, Chaudhari G, Lew C, Lee A, Rauschecker AM, Haskell-Mendoza AP, Wu YW, Calabrese E. Automated neonatal nnU-Net brain MRI extractor trained on a large multi-institutional dataset. Scientific Reports 2024. PMID: 38403673


  14. Morell AS, Monsell SE, Cornet MC, Wisnowski JL, McKinstry RC, Mathur AM, Li Y, Glass HC, Gonzalez FF, Mayock DE, Benninger KL, Van Meurs KP, Lampland AL, Wu TW, Riley D, Mietzsch U, Chalak L, Flibotte J, Weitkamp JH, Ahmad KA, Yanowitz TD, Baserga M, Merhar S, Rao R, Sokol GM, Comstock BA, Heagerty PJ, Juul SE, Wu YW. Genetic and Congenital Anomalies in Infants With Hypoxic-Ischemic Encephalopathy. Pediatric neurology 2024. PMID: 38518503


  15. Numis AL, Glass HC, Comstock BA, Gonzalez F, Maitre NL, Massey SL, Mayock DE, Mietzsch U, Natarajan N, Sokol GM, Bonifacio S, Van Meurs K, Thomas C, Ahmad K, Heagerty P, Juul SE, Wu YW, Wusthoff CJ. Relationship of Neonatal Seizure Burden Prior to Treatment and Response to Initial Anti-Seizure Medication. The Journal of pediatrics 2024. PMID: 38360261


  16. Wu TW, Schmicker R, Wood TR, Mietzsch U, Comstock B, Heagerty PJ, Rao R, Gonzalez F, Juul S, Wu YW. Esophageal versus Rectal Temperature Monitoring during Whole-body Therapeutic Hypothermia for Hypoxic-ischemic Encephalopathy: Association with Short and Long-term Outcomes. The Journal of pediatrics 2024. PMID: 38309524


  17. Vargas-Calixto J, Wu YW, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick P, Kearney R. Prediction of Hypoxic-Ischemic Encephalopathy Using Events in Fetal Heart Rate and Uterine Pressure. Computing in cardiology 2023. PMID: 39364002


  18. Glass HC, Numis AL, Comstock BA, Gonzalez FF, Mietzsch U, Bonifacio SL, Massey S, Thomas C, Natarajan N, Mayock DE, Sokol GM, Van Meurs KP, Ahmad KA, Maitre N, Heagerty PJ, Juul SE, Wu YW, Wusthoff CJ. Association of EEG Background and Neurodevelopmental Outcome in Neonates With Hypoxic-Ischemic Encephalopathy Receiving Hypothermia. Neurology 2023. PMID: 37816642


  19. Rao R, Comstock BA, Wu TW, Mietzsch U, Mayock DE, Gonzalez FF, Wood TR, Heagerty PJ, Juul SE, Wu YW. Time to Reaching Target Cooling Temperature and Two-Year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2023. PMID: 38006967


  20. Vargas-Calixto J, Wu YW, Kuzniewicz M, Cornet MC, Forquer H, Gerstley L, Hamilton E, Warrick PA, Kearney RE. Accounting for Nulliparity in the Prediction of Hypoxic-Ischemic Encephalopathy Using Cardiotocography. ... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics 2023. PMID: 38031586


  21. Wisnowski JL, Monsell SE, Bluml S, Goodman AM, Li Y, Comstock B, Heagerty P, Juul SE, Wu YW, McKinstry RC, Mathur A, HEAL Consortium. Brain Injury Outcomes after Adjuvant Erythropoietin Neuroprotection for Moderate or Severe Neonatal Hypoxic-Ischemic Encephalopathy: A Report from the HEAL Trial. Developmental neuroscience 2023. PMID: 37906983


  22. Mike JK, White Y, Hutchings RS, Vento C, Ha J, Manzoor H, Lee D, Losser C, Arellano K, Vanhatalo O, Seifert E, Gunewardena A, Wen B, Wang L, Wang A, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JVS, Long-Boyle J, Wu YW, Fineman JR, Ferriero DM, Maltepe E. Perinatal Azithromycin Provides Limited Neuroprotection in an Ovine Model of Neonatal Hypoxic-Ischemic Encephalopathy. Stroke 2023. PMID: 37846563


  23. Croen LA, Ames JL, Qian Y, Alexeeff S, Ashwood P, Gunderson EP, Wu YW, Boghossian AS, Yolken R, Van de Water J, Weiss LA. Inflammatory Conditions During Pregnancy and Risk of Autism and Other Neurodevelopmental Disorders. Biological Psychiatry Global Open Science 2023. PMID: 38045769


  24. Mietzsch U, Wood TR, Wu TW, Natarajan N, Glass HC, Gonzalez FF, Mayock DE, Comstock BA, Heagerty PJ, Juul SE, Wu YW, HEAL Study Group. Early Glycemic State and Outcomes of Neonates With Hypoxic-Ischemic Encephalopathy. Pediatrics 2023. PMID: 37655394


  25. Gonzalez FF, Voldal E, Comstock BA, Mayock DE, Goodman AM, Cornet MC, Wu TW, Redline RW, Heagerty P, Juul SE, Wu YW. Placental Histologic Abnormalities and 2-Year Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy. Neonatology 2023. PMID: 37742617


  26. Wu YW, Wisnowski JL, Glass HC, Mathur AM, Li Y, Monsell SE, Juul SE, McKinstry RC. Advancing brain MRI as a prognostic indicator in hypoxic-ischemic encephalopathy. Pediatric research 2023. PMID: 37696979


  27. Vesoulis ZA, Trivedi SB, Morris HF, McKinstry RC, Li Y, Mathur AM, Wu YW. Deep Learning to Optimize Magnetic Resonance Imaging Prediction of Motor Outcomes After Hypoxic-Ischemic Encephalopathy. Pediatric neurology 2023. PMID: 37774643


  28. Cornet MC, Kuzniewicz M, Scheffler A, Forquer H, Hamilton E, Newman TB, Wu YW. Perinatal Hypoxic-Ischemic Encephalopathy: Incidence Over Time Within a Modern US Birth Cohort. Pediatric neurology 2023. PMID: 37883841


  29. Juul SE, Voldal E, Comstock BA, Massaro AN, Bammler TK, Mayock DE, Heagerty PJ, Wu YW, Numis AL, HEAL consortium. Association of High-Dose Erythropoietin With Circulating Biomarkers and Neurodevelopmental Outcomes Among Neonates With Hypoxic Ischemic Encephalopathy: A Secondary Analysis of the HEAL Randomized Clinical Trial. JAMA network open 2023. PMID: 37418263


  30. Chalak LF, Kang S, Kota S, Liu H, Liu Y, Juul SE, Wu YW. Evaluation of neurovascular coupling during neuroprotective therapies: A single site HEAL ancillary study. Early human development 2023. PMID: 37419079


  31. Juul SE, Comstock BA, Cornet MC, Gonzalez FF, Mayock DE, Glass HC, Schreiber MD, Heagerty PJ, Wu YW. Safety of High Dose Erythropoietin Used with Therapeutic Hypothermia as Treatment for Newborn Hypoxic-Ischemic Encephalopathy: Secondary Analysis of the HEAL Randomized Controlled Trial. The Journal of pediatrics 2023. PMID: 37019334


  32. Wu YW, Monsell SE, Glass HC, Wisnowski JL, Mathur AM, McKinstry RC, Bluml S, Gonzalez FF, Comstock BA, Heagerty PJ, Juul SE. How well does neonatal neuroimaging correlate with neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy? Pediatric research 2023. PMID: 36859442


  33. Guttmann KF, Li S, Wu YW, Juul SE, Wilfond BS, Weiss EM, HEAL Recruitment Collaborative. Factors That Impact Hospital-Specific Enrollment Rates for a Neonatal Clinical Trial: An Analysis of the HEAL Study. Ethics & human research 2023. PMID: 36691692


  34. Glass HC, Wusthoff CJ, Comstock BA, Numis AL, Gonzalez FF, Maitre N, Massey SL, Mayock DE, Mietzsch U, Natarajan N, Sokol GM, Bonifacio SL, Van Meurs KP, Thomas C, Ahmad KA, Heagerty PJ, Juul SE, Wu YW. Risk of seizures in neonates with hypoxic-ischemic encephalopathy receiving hypothermia plus erythropoietin or placebo. Pediatric research 2022. PMID: 36470964


  35. Zhou L, Meng Q, von Ehrenstein OS, Xiao J, Gao Y, Wu YW, Ritz B, Liew Z. Parental Age and Childhood Risk for Cerebral Palsy in California. The Journal of pediatrics 2022. PMID: 36372095


  36. Molloy EJ, El-Dib M, Juul SE, Benders M, Gonzalez F, Bearer C, Wu YW, Robertson NJ, Hurley T, Branagan A, Michael Cotten C, Tan S, Laptook A, Austin T, Mohammad K, Rogers E, Luyt K, Bonifacio S, Soul JS, Gunn AJ, Newborn Brain Society Guidelines and Publications Committee. Neuroprotective therapies in the NICU in term infants: present and future. Pediatric research 2022. PMID: 36195634


  37. Cornet MC, Grose C, Vexler Z, Wu YW, Fullerton HJ. The Role of Infection and Inflammation in the Pathogenesis of Pediatric Arterial Ischemic Stroke. Seminars in pediatric neurology 2022. PMID: 36456035


  38. Wu YW, Comstock BA, Gonzalez FF, Mayock DE, Goodman AM, Maitre NL, Chang T, Van Meurs KP, Lampland AL, Bendel-Stenzel E, Mathur AM, Wu TW, Riley D, Mietzsch U, Chalak L, Flibotte J, Weitkamp JH, Ahmad KA, Yanowitz TD, Baserga M, Poindexter BB, Rogers EE, Lowe JR, Kuban KCK, O'Shea TM, Wisnowski JL, McKinstry RC, Bluml S, Bonifacio S, Benninger KL, Rao R, Smyser CD, Sokol GM, Merhar S, Schreiber MD, Glass HC, Heagerty PJ, Juul SE, HEAL Consortium. Trial of Erythropoietin for Hypoxic-Ischemic Encephalopathy in Newborns. The New England journal of medicine 2022. PMID: 35830641


  39. Mike JK, Wu KY, White Y, Pathipati P, Ndjamen B, Hutchings RS, Losser C, Vento C, Arellano K, Vanhatalo O, Ostrin S, Windsor C, Ha J, Alhassen Z, Goudy BD, Vali P, Lakshminrusimha S, Gobburu JV, Long-Boyle J, Chen P, Wu YW, Fineman JR, Ferriero DM, Maltepe E. Defining longer term outcomes in an ovine model of moderate perinatal hypoxia-ischemia. 2022. PMID: 35588703


  40. Li Y, Wisnowski JL, Chalak L, Mathur AM, McKinstry RC, Licona G, Mayock DE, Chang T, Van Meurs KP, Wu TW, Ahmad KA, Cornet MC, Rao R, Scheffler A, Wu YW. Mild hypoxic-ischemic encephalopathy (HIE): timing and pattern of MRI brain injury. 2022. PMID: 35354930


  41. Weiss EM, Guttmann KF, Olszewski AE, Magnus BE, Li S, Kim SY, Shah AR, Juul SE, Wu YW, Ahmad KA, Bendel-Stenzel E, Isaza NA, Lampland AL, Mathur AM, Rao R, Riley D, Russell DG, Salih ZNI, Torr CB, Weitkamp JH, Anani UE, Chang T, Dudley J, Flibotte J, Havrilla EM, O'Kane AC, Perez K, Stanley BJ, Shah SK, Wilfond BS. Parental Enrollment Decision-making for a Neonatal Clinical Trial. The Journal of pediatrics 2021. PMID: 34400207


  42. Holmes BB, Russ JB, Wu YW, Gallagher RC, Gano D. Clinical Reasoning: A 2-Day-Old Boy With Sudden Cardiac Arrest and Encephalopathy. Neurology 2021. PMID: 34158382


  43. Chalak L, Redline RW, Goodman AM, Juul SE, Chang T, Yanowitz TD, Maitre N, Mayock DE, Lampland AL, Bendel-Stenzel E, Riley D, Mathur AM, Rao R, Van Meurs KP, Wu TW, Gonzalez FF, Flibotte J, Mietzsch U, Sokol GM, Ahmad KA, Baserga M, Weitkamp JH, Poindexter BB, Comstock BA, Wu YW. Acute and Chronic Placental Abnormalities in a Multicenter Cohort of Newborn Infants with Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2021. PMID: 34144032


  44. Wisnowski JL, Bluml S, Panigrahy A, Mathur AM, Berman J, Chen PK, Dix J, Flynn T, Fricke S, Friedman SD, Head HW, Ho CY, Kline-Fath B, Oveson M, Patterson R, Pruthi S, Rollins N, Ramos YM, Rampton J, Rusin J, Shaw DW, Smith M, Tkach J, Vasanawala S, Vossough A, Whitehead MT, Xu D, Yeom K, Comstock B, Heagerty PJ, Juul SE, Wu YW, McKinstry RC, HEAL Study Group. Integrating neuroimaging biomarkers into the multicentre, high-dose erythropoietin for asphyxia and encephalopathy (HEAL) trial: rationale, protocol and harmonisation. BMJ open 2021. PMID: 33888528


  45. Weiss EM, Olszewski AE, Guttmann KF, Magnus BE, Li S, Shah AR, Juul SE, Wu YW, Ahmad KA, Bendel-Stenzel E, Isaza NA, Lampland AL, Mathur AM, Rao R, Riley D, Russell DG, Salih ZNI, Torr CB, Weitkamp JH, Anani UE, Chang T, Dudley J, Flibotte J, Havrilla EM, Kathen CM, O'Kane AC, Perez K, Stanley BJ, Wilfond BS, Shah SK. Parental Factors Associated With the Decision to Participate in a Neonatal Clinical Trial. JAMA network open 2021. PMID: 33433595


  46. Guttmann KF, Wu YW, Juul SE, Weiss EM. Consent Related Challenges for Neonatal Clinical Trials. The American journal of bioethics : AJOB 2020. PMID: 32364480


  47. Wu YW, Goodman AM, Chang T, Mulkey SB, Gonzalez FF, Mayock DE, Juul SE, Mathur AM, Van Meurs K, McKinstry RC, Redline RW. Placental pathology and neonatal brain MRI in a randomized trial of erythropoietin for hypoxic-ischemic encephalopathy. Pediatric research 2019. PMID: 31261373


  48. Massaro AN, Wu YW, Bammler TK, MacDonald JW, Mathur A, Chang T, Mayock D, Mulkey SB, van Meurs K, Afsharinejad Z, Juul SE. Dried blood spot compared to plasma measurements of blood-based biomarkers of brain injury in neonatal encephalopathy. Pediatric research 2019. PMID: 30661082


  49. Newman TB, Wu YW, Kuzniewicz MW, Grimes BA, McCulloch CE. Childhood Seizures After Phototherapy. Pediatrics 2018. PMID: 30249623


  50. Parker SJ, Kuzniewicz M, Niki H, Wu YW. Antenatal and Intrapartum Risk Factors for Hypoxic-Ischemic Encephalopathy in a US Birth Cohort. The Journal of pediatrics 2018. PMID: 30270166


  51. Juul SE, Comstock BA, Heagerty PJ, Mayock DE, Goodman AM, Hauge S, Gonzalez F, Wu YW. High-Dose Erythropoietin for Asphyxia and Encephalopathy (HEAL): A Randomized Controlled Trial - Background, Aims, and Study Protocol. Neonatology 2018. PMID: 29514165


  52. Massaro AN, Wu YW, Bammler TK, Comstock B, Mathur A, McKinstry RC, Chang T, Mayock DE, Mulkey SB, Van Meurs K, Juul S. Plasma Biomarkers of Brain Injury in Neonatal Hypoxic-Ischemic Encephalopathy. The Journal of pediatrics 2018. PMID: 29478510


  53. Mulkey SB, Ramakrishnaiah RH, McKinstry RC, Chang T, Mathur AM, Mayock DE, Van Meurs KP, Schaefer GB, Luo C, Bai S, Juul SE, Wu YW. Erythropoietin and Brain Magnetic Resonance Imaging Findings in Hypoxic-Ischemic Encephalopathy: Volume of Acute Brain Injury and 1-Year Neurodevelopmental Outcome. The Journal of pediatrics 2017. PMID: 28456387


  54. Frymoyer A, Juul SE, Massaro AN, Bammler TK, Wu YW. High-dose erythropoietin population pharmacokinetics in neonates with hypoxic-ischemic encephalopathy receiving hypothermia. Pediatric research 2017. PMID: 28099423


  55. Wu YW, Kuzniewicz MW, Croen L, Walsh EM, McCulloch CE, Newman TB. Risk of Autism Associated With Hyperbilirubinemia and Phototherapy. Pediatrics 2016. PMID: 27669736


  56. Wu YW, Mathur AM, Chang T, McKinstry RC, Mulkey SB, Mayock DE, Van Meurs KP, Rogers EE, Gonzalez FF, Comstock BA, Juul SE, Msall ME, Bonifacio SL, Glass HC, Massaro AN, Dong L, Tan KW, Heagerty PJ, Ballard RA. High-Dose Erythropoietin and Hypothermia for Hypoxic-Ischemic Encephalopathy: A Phase II Trial. Pediatrics 2016. PMID: 27244862


  57. Ananth AL, Robichaux-Viehoever A, Kim YM, Hanson-Kahn A, Cox R, Enns GM, Strober J, Willing M, Schlaggar BL, Wu YW, Bernstein JA. Clinical Course of Six Children With GNAO1 Mutations Causing a Severe and Distinctive Movement Disorder. Pediatric neurology 2016. PMID: 27068059


  58. Schwarz MD, Li M, Tsao J, Zhou R, Wu YW, Sankar R, Wu JY, Hussain SA. A lack of clinically apparent vision loss among patients treated with vigabatrin with infantile spasms: The UCLA experience. Epilepsy & behavior : E&B 2016. PMID: 26921595


  59. Bear JJ, Wu YW. Maternal Infections During Pregnancy and Cerebral Palsy in the Child. Pediatric neurology 2016. PMID: 26857522


  60. Shang L, Henderson LB, Cho MT, Petrey DS, Fong CT, Haude KM, Shur N, Lundberg J, Hauser N, Carmichael J, Innis J, Schuette J, Wu YW, Asaikar S, Pearson M, Folk L, Retterer K, Monaghan KG, Chung WK. De novo missense variants in PPP2R5D are associated with intellectual disability, macrocephaly, hypotonia, and autism. Neurogenetics 2015. PMID: 26576547


  61. Wu YW, Sullivan J, McDaniel SS, Meisler MH, Walsh EM, Li SX, Kuzniewicz MW. Incidence of Dravet Syndrome in a US Population. Pediatrics 2015. PMID: 26438699


  62. Wickremasinghe AC, Risley RJ, Kuzniewicz MW, Wu YW, Walsh EM, Wi S, McCulloch CE, Newman TB. Risk of Sensorineural Hearing Loss and Bilirubin Exchange Transfusion Thresholds. Pediatrics 2015. PMID: 26283777


  63. Hannah Glass, Yvonne Wu. Epidemiology of neonatal seizures. Journal of Pediatric Neurology 2015. PMID:


  64. Yvonne Wu, Petra Liljestrand, Donna Ferriero, Jean Hayward, Rita Jeremy, Gabriel Escobar, Thomas Newman. Prevalence of motor abnormalities among healthy 5-year-old children. Journal of Pediatric Neurology 2015. PMID:


  65. Wu YW, Mehravari AS, Numis AL, Gross P. Cerebral palsy research funding from the National Institutes of Health, 2001 to 2013. Developmental medicine and child neurology 2015. PMID: 25951080


  66. Wu YW, Gonzalez FF. Erythropoietin: a novel therapy for hypoxic-ischaemic encephalopathy? Developmental medicine and child neurology 2015. PMID: 25800490


  67. Wu YW, Kuzniewicz MW, Wickremasinghe AC, Walsh EM, Wi S, McCulloch CE, Newman TB. Risk for cerebral palsy in infants with total serum bilirubin levels at or above the exchange transfusion threshold: a population-based study. JAMA pediatrics 2015. PMID: 25560920


  68. Rogers EE, Bonifacio SL, Glass HC, Juul SE, Chang T, Mayock DE, Durand DJ, Song D, Barkovich AJ, Ballard RA, Wu YW. Erythropoietin and hypothermia for hypoxic-ischemic encephalopathy. Pediatric neurology 2014. PMID: 25439577


  69. Kuzniewicz MW, Wickremasinghe AC, Wu YW, McCulloch CE, Walsh EM, Wi S, Newman TB. Incidence, etiology, and outcomes of hazardous hyperbilirubinemia in newborns. Pediatrics 2014. PMID: 25092943


  70. Brooks JC, Strauss DJ, Shavelle RM, Tran LM, Rosenbloom L, Wu YW. Recent trends in cerebral palsy survival. Part II: individual survival prognosis. Developmental medicine and child neurology 2014. PMID: 25041081


  71. Brooks JC, Strauss DJ, Shavelle RM, Tran LM, Rosenbloom L, Wu YW. Recent trends in cerebral palsy survival. Part I: period and cohort effects. Developmental medicine and child neurology 2014. PMID: 24966011


  72. Khankhanian P, Baranzini SE, Johnson BA, Madireddy L, Nickles D, Croen LA, Wu YW. Sequencing of the IL6 gene in a case-control study of cerebral palsy in children. BMC medical genetics 2013. PMID: 24314052


  73. Wu YW, Hess CP, Singhal NS, Groden C, Toro C. Idiopathic basal ganglia calcifications: an atypical presentation of PKAN. Pediatric neurology 2013. PMID: 23968566


  74. Crisham Janik MD, Newman TB, Cheng YW, Xing G, Gilbert WM, Wu YW. Maternal diagnosis of obesity and risk of cerebral palsy in the child. The Journal of pediatrics 2013. PMID: 23932316


  75. Grether JK, Qian Y, Croughan MS, Wu YW, Schembri M, Camarano L, Croen LA. Is infertility associated with childhood autism? Journal of autism and developmental disorders 2013. PMID: 22777105


  76. Gelfand AA, Croen LA, Torres AR, Wu YW. Genetic risk factors for perinatal arterial ischemic stroke. Pediatric neurology 2013. PMID: 23290018


  77. Gardner MA, Li BC, Wu YW, Slavotinek AM. Intraparenchymal hemorrhage in a neonate with cleidocranial dysostosis. Pediatric neurology 2012. PMID: 23127269


  78. Wu YW, Bauer LA, Ballard RA, Ferriero DM, Glidden DV, Mayock DE, Chang T, Durand DJ, Song D, Bonifacio SL, Gonzalez FF, Glass HC, Juul SE. Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics 2012. PMID: 23008465


  79. Lang TC, Fuentes-Afflick E, Gilbert WM, Newman TB, Xing G, Wu YW. Cerebral palsy among Asian ethnic subgroups. Pediatrics 2012. PMID: 22430449


  80. Kenneth F. Swaiman, Yvonne W. Wu. Chapter 69 Cerebral Palsy. Swaiman\u0027s Pediatric Neurology 2012. PMID:


  81. Wu YW, Croen LA, Vanderwerf A, Gelfand AA, Torres AR. Candidate genes and risk for CP: a population-based study. Pediatric research 2011. PMID: 21857382


  82. Jeng S, Gupta N, Wrensch M, Zhao S, Wu YW. Prevalence of congenital hydrocephalus in California, 1991-2000. Pediatric neurology 2011. PMID: 21763944


  83. Yvonne W. Wu, Guibo Xing, Elena Fuentes-Afflick, Beate Danielson, Lloyd H. Smith, William M. Gilbert. Racial, Ethnic, and Socioeconomic Disparities in the Prevalence of Cerebral Palsy. Obstetrical & Gynecological Survey 2011. PMID:


  84. Yvonne W. Wu, Trinh N. Pham, Beate Danielsen, Dena Towner, Lloyd Smith, S. Claiborne Johnston. Nighttime Delivery and Risk of Neonatal Encephalopathy. Obstetrical & Gynecological Survey 2011. PMID:


  85. Sukhov A, Wu Y, Xing G, Smith LH, Gilbert WM. Risk factors associated with cerebral palsy in preterm infants. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2011. PMID: 21463212


  86. Brooks JC, Fisher-Owens SA, Wu YW, Strauss DJ, Newman TB. Evidence suggests there was not a "resurgence" of kernicterus in the 1990s. Pediatrics 2011. PMID: 21444599


  87. Wu YW, Xing G, Fuentes-Afflick E, Danielson B, Smith LH, Gilbert WM. Racial, ethnic, and socioeconomic disparities in the prevalence of cerebral palsy. Pediatrics 2011. PMID: 21339278


  88. Wu YW, Pham TN, Danielsen B, Towner D, Smith L, Johnston SC. Nighttime delivery and risk of neonatal encephalopathy. American journal of obstetrics and gynecology 2010. PMID: 21074140


  89. Yvonne W. Wu, Lisa A. Croen. Reply. Annals of neurology 2010. PMID:


  90. Wu YW, Croen LA, Torres AR, Van De Water J, Grether JK, Hsu NN. Interleukin-6 genotype and risk for cerebral palsy in term and near-term infants. Annals of neurology 2009. PMID: 19938160


  91. Agrawal N, Johnston SC, Wu YW, Sidney S, Fullerton HJ. Imaging data reveal a higher pediatric stroke incidence than prior US estimates. Stroke 2009. PMID: 19762687


  92. Aitken LA, Lindan CE, Sidney S, Gupta N, Barkovich AJ, Sorel M, Wu YW. Chiari type I malformation in a pediatric population. Pediatric neurology 2009. PMID: 19433279


  93. Armstrong-Wells J, Johnston SC, Wu YW, Sidney S, Fullerton HJ. Prevalence and predictors of perinatal hemorrhagic stroke: results from the kaiser pediatric stroke study. Pediatrics 2009. PMID: 19255009


  94. Jordan LC, Johnston SC, Wu YW, Sidney S, Fullerton HJ. The importance of cerebral aneurysms in childhood hemorrhagic stroke: a population-based study. Stroke 2008. PMID: 19023102


  95. Glass HC, Pham TN, Danielsen B, Towner D, Glidden D, Wu YW. Antenatal and intrapartum risk factors for seizures in term newborns: a population-based study, California 1998-2002. The Journal of pediatrics 2008. PMID: 18760807


  96. Anderson JE, Teitel D, Wu YW. Venous hum causing tinnitus: case report and review of the literature. Clinical pediatrics 2008. PMID: 18626105


  97. Liljestrand P, Jeremy RJ, Wu YW, Ferriero DM, Escobar GJ, Newman TB. Use of the motor performance checklist to study motor outcomes in 5-year-olds. Journal of paediatrics and child health 2007. PMID: 17803665


  98. Day SM, Wu YW, Strauss DJ, Shavelle RM, Reynolds RJ. Change in ambulatory ability of adolescents and young adults with cerebral palsy. Developmental medicine and child neurology 2007. PMID: 17718819


  99. Wu Y, Green NL, Wrensch MR, Zhao S, Gupta N. Ventriculoperitoneal shunt complications in California: 1990 to 2000. Neurosurgery 2007. PMID: 17881969


  100. Fullerton HJ, Wu YW, Sidney S, Johnston SC. Recurrent hemorrhagic stroke in children: a population-based cohort study. Stroke 2007. PMID: 17761928


  101. Escobar GJ, Liljestrand P, Hudes ES, Ferriero DM, Wu YW, Jeremy RJ, Newman TB. Five-year neurodevelopmental outcome of neonatal dehydration. The Journal of pediatrics 2007. PMID: 17643761


  102. Gupta N, Park J, Solomon C, Kranz DA, Wrensch M, Wu YW. Long-term outcomes in patients with treated childhood hydrocephalus. Journal of neurosurgery 2007. PMID: 17566197


  103. Day SM, Strauss DJ, Vachon PJ, Rosenbloom L, Shavelle RM, Wu YW. Growth patterns in a population of children and adolescents with cerebral palsy. Developmental medicine and child neurology 2007. PMID: 17355471


  104. Hecht JH, Glenn OA, Wara DW, Wu YW. JC virus granule cell neuronopathy in a child with CD40 ligand deficiency. Pediatric neurology 2007. PMID: 17352955


  105. Fullerton HJ, Wu YW, Sidney S, Johnston SC. Risk of recurrent childhood arterial ischemic stroke in a population-based cohort: the importance of cerebrovascular imaging. Pediatrics 2007. PMID: 17332202


  106. Wu YW, Croen LA, Henning L, Najjar DV, Schembri M, Croughan MS. Potential association between infertility and spinal neural tube defects in offspring. Birth defects research. Part A, Clinical and molecular teratology 2006. PMID: 17022023


  107. Miller SP, Wu YW, Lee J, Lammer EJ, Iovannisci DM, Glidden DV, Bonifacio SL, Collins A, Shaw GM, Barkovich AJ, Ferriero DM. Candidate gene polymorphisms do not differ between newborns with stroke and normal controls. Stroke 2006. PMID: 17008620


  108. Wu YW, Lindan CE, Henning LH, Yoshida CK, Fullerton HJ, Ferriero DM, Barkovich AJ, Croen LA. Neuroimaging abnormalities in infants with congenital hemiparesis. Pediatric neurology 2006. PMID: 16939859


  109. Wu YW, Croen LA, Shah SJ, Newman TB, Najjar DV. Cerebral palsy in a term population: risk factors and neuroimaging findings. Pediatrics 2006. PMID: 16882824


  110. Newman TB, Liljestrand P, Jeremy RJ, Ferriero DM, Wu YW, Hudes ES, Escobar GJ, Jaundice and Infant Feeding Study Team. Outcomes among newborns with total serum bilirubin levels of 25 mg per deciliter or more. The New England journal of medicine 2006. PMID: 16672700


  111. Wu YW, Lynch JK, Nelson KB. Perinatal arterial stroke: understanding mechanisms and outcomes. Seminars in neurology 2005. PMID: 16341998


  112. Steven P. Miller, Vijay Ramaswamy, David Michelson, A James Barkovich, Barbara Holshouser, Nathaniel Wycliffe, David V. Gudden, Douglas Deming, Colin Partridge, Yvonne W. Wu, Stephen Ashwal, Donna M. Ferrero. Patterns of Brain Injury in Term Neonatal Encephalopathy. Obstetrical & Gynecological Survey 2005. PMID:


  113. Lee J, Croen LA, Lindan C, Nash KB, Yoshida CK, Ferriero DM, Barkovich AJ, Wu YW. Predictors of outcome in perinatal arterial stroke: a population-based study. Annals of neurology 2005. PMID: 16010659


  114. Janet Lee, Lisa A. Croen, Kendall H. Backstrand, Cathleen K. Yoshida, Louis H. Henning, Camilla Lindan, Donna M. Ferriero, Heather J. Fullerton, A J. Barkovich, Yvonne W. Wu. Maternal and Infant Characteristics Associated With Perinatal Arterial Stroke in the Infant. Obstetrical & Gynecological Survey 2005. PMID:


  115. Miller SP, Ramaswamy V, Michelson D, Barkovich AJ, Holshouser B, Wycliffe N, Glidden DV, Deming D, Partridge JC, Wu YW, Ashwal S, Ferriero DM. Patterns of brain injury in term neonatal encephalopathy. The Journal of pediatrics 2005. PMID: 15812446


  116. Lee J, Croen LA, Backstrand KH, Yoshida CK, Henning LH, Lindan C, Ferriero DM, Fullerton HJ, Barkovich AJ, Wu YW. Maternal and infant characteristics associated with perinatal arterial stroke in the infant. JAMA 2005. PMID: 15701914


  117. Wu YW, Backstrand KH, Zhao S, Fullerton HJ, Johnston SC. Declining diagnosis of birth asphyxia in California: 1991-2000. Pediatrics 2004. PMID: 15574618


  118. Wu YW, Day SM, Strauss DJ, Shavelle RM. Prognosis for ambulation in cerebral palsy: a population-based study. Pediatrics 2004. PMID: 15520106


  119. Wu YW, March WM, Croen LA, Grether JK, Escobar GJ, Newman TB. Perinatal stroke in children with motor impairment: a population-based study. Pediatrics 2004. PMID: 15342829


  120. Yvonne W. Wu, Gabriel J. Escobar, Judith K. Grether, Lisa A. Croen, John D. Greene, Thomas B. Newman. Chorioamnionitis and Cerebral Palsy in Term and Near-Term Infants. Obstetrical & Gynecological Survey 2004. PMID:


  121. Jackson RA, Gibson KA, Wu YW, Croughan MS. Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstetrics and gynecology 2004. PMID: 14990421


  122. Wu YW, Escobar GJ, Grether JK, Croen LA, Greene JD, Newman TB. Chorioamnionitis and cerebral palsy in term and near-term infants. JAMA 2003. PMID: 14645309


  123. Fullerton HJ, Wu YW, Zhao S, Johnston SC. Risk of stroke in children: ethnic and gender disparities. Neurology 2003. PMID: 12874397


  124. Wu YW, Hamrick SE, Miller SP, Haward MF, Lai MC, Callen PW, Barkovich AJ, Ferriero DM. Intraventricular hemorrhage in term neonates caused by sinovenous thrombosis. Annals of neurology 2003. PMID: 12838529


  125. Strauss DJ, Day SM, Shavelle RM, Wu YW. Remote symptomatic epilepsy: does seizure severity increase mortality? Neurology 2003. PMID: 12578917


  126. Day S, Strauss D, Shavelle R, Wu YW. Excess mortality in remote symptomatic epilepsy. Journal of insurance medicine (New York, N.Y.) 2003. PMID: 14971087


  127. Wu YW, Miller SP, Chin K, Collins AE, Lomeli SC, Chuang NA, Barkovich AJ, Ferriero DM. Multiple risk factors in neonatal sinovenous thrombosis. Neurology 2002. PMID: 12177381


  128. Wu YW. Systematic review of chorioamnionitis and cerebral palsy. Mental retardation and developmental disabilities research reviews 2002. PMID: 11921383