Ann Petru, MD

Ann Petru, MD is a Pediatric Infectious Diseases physician who has been working at Children’s Hospital Oakland since completing her residency there. She was involved in many clinical trials in the 1980s and 1990s, then started to focus more on HIV and AIDS as that epidemic started to affect children. In addition to HIV and AIDS, she has focused on common and challenging problems in the field, including use of antibiotics in children, common “Staph” and “Strep” infections, bacterial and other forms of meningitis, Epstein-Barr virus infection (EBV), and coccidioidomycosis (the fungus that causes Valley Fever). However, her primary focus has been the treatment support of children living with HIV/AIDS and preventing transmission of HIV from mothers to their babies.

Dr. Petru provided care for the first pediatric HIV/AIDS case in the Bay Area in 1983. In 1986, she started the Pediatric HIV/AIDS Program, which has treated more than 800 HIV-infected and HIV-exposed infants, children and adolescents. Many of her patients were among the first to participate in clinical trials that provided AZT treatment for children, then followed by many other drugs as they were becoming available for adults and where data in children was lacking. These groundbreaking studies allowed her and her staff to evaluate many drug combinations for HIV management, immunizations in children with HIV, and the long-term effects on children receiving drugs for HIV disease. Because drug therapies have been so successful, children are living much longer and their treatment has become far simpler and better tolerated. Aggressive identification of HIV infection before and during pregnancy and improved therapies have dramatically reduced transmission of HIV from mothers to their children over the last 20 years. However, many families in the Bay Area and other areas in northern California are adopting children with HIV infection from other countries, so her clinic continues to see a slow but steady influx of new patients.
Education
Residency, - Pediatrics, Children's Hospital & Research Center
MD, - , University of California
Honors and Awards
  • Women's Hall of Fame Inductee, Alameda County, 2015
  • Best East Bay Doctors, Oakland Magazine, 2009-2010
  • Bronze Bambino, Children's Hospital Oakland, 2008
  • "Miracle-Maker" Award, Children's Miracle Network, 1994
  • Teacher of the Year, Children's Hospital Oakland, 1985
Publications
  1. From Microcytosis to Macrodiagnosis.
  2. Twelve-year-old With Chronic Chest and Abdominal Pain.
  3. Paucity of Intact Non-Induced Provirus with Early, Long-Term Antiretroviral Therapy of Perinatal HIV Infection.
  4. Comparison of moderate and severe hospitalized Pediatric 2009 H1N1 influenza cases.
  5. Photo quiz. Painful arthritis and extremity rash in an 8-year-old boy.
  6. Vaccine-acquired rotavirus in infants with severe combined immunodeficiency.
  7. Purulent pericardial effusion in a 14-year-old girl.
  8. Rhinovirus associated with severe lower respiratory tract infections in children.
  9. Altered iron metabolism in children with human immunodeficiency virus disease.
  10. Severe pneumonia due to adenovirus serotype 14: a new respiratory threat?
  11. A seven-month-old infant with acute onset of neurologic deterioration.
  12. Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen.
  13. Temporal trends in early clinical manifestations of perinatal HIV infection in a population-based cohort.
  14. Safety and immunogenicity of a heptavalent pneumococcal conjugate vaccine in infants with human immunodeficiency virus type 1 infection.
  15. When the time comes to talk about HIV: factors associated with diagnostic disclosure and emotional distress in HIV-infected children.
  16. Oral ganciclovir in children: pharmacokinetics, safety, tolerance, and antiviral effects. The Pediatric AIDS Clinical Trials Group.
  17. Oral manifestations and dental status in paediatric HIV infection.
  18. Use of human immunodeficiency virus (HIV) human hyperimmune immunoglobulin in HIV type 1-infected children (Pediatric AIDS clinical trials group protocol 273).
  19. Influence of HLA alleles on the rate of progression of vertically transmitted HIV infection in children: association of several HLA-DR13 alleles with long-term survivorship and the potential association of HLA-A*2301 with rapid progression to AIDS. Long-T
  20. A descriptive survey of pediatric human immunodeficiency virus-infected long-term survivors.
  21. Severe esophagitis in a newborn infant.
  22. Altered representation of naive and memory CD8 T cell subsets in HIV-infected children.
  23. No evidence of perinatal transmission of HTLV-II.
  24. Reliability of polymerase chain reaction in the detection of human immunodeficiency virus infection in children.
  25. Foreign body pulmonary granulomas in an abuser of nasally inhaled drugs.
  26. Multisystem disease in an eight-year-old boy.
  27. Fatal adenovirus infection in a child with acquired immunodeficiency syndrome.
  28. Randomized comparative study of ampicillin/sulbactam vs. ceftriaxone for treatment of soft tissue and skeletal infections in children.
  29. African sleeping sickness in the United States. Successful treatment with eflornithine.
  30. Malassezia furfur: a cause of occlusion of percutaneous central venous catheters in infants in the intensive care nursery.
  31. Mycoplasmas: their role in pediatric disease.
  32. Esophagitis associated with Candida infection in a neonate.