Benjamin Huang, MD

Wong JC, Weinfurtner KM, Westover T, Kim J, Lebish EJ, Del Pilar Alzamora M, Huang BJ, Walsh M, Abdelhamed S, Ma J, Klco JM, Shannon K. 5G2 mutant mice model loss of a commonly deleted segment of chromosome 7q22 in myeloid malignancies. Leukemia 2024. PMID: 38443608

Tarlock K, Gerbing RB, Ries RE, Smith JL, Leonti AR, Huang BJ, Kirkey DC, Robinson L, Peplinski JH, Lange B, Cooper TM, Gamis AS, Kolb EA, Aplenc R, Pollard JA, Meshinchi S. Prognostic Impact of Co-occurring Mutations in FLT3-ITD Pediatric Acute Myeloid Leukemia. Blood advances 2024. PMID: 38295280

Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Yang W, Fan Y, Wu G, Baker SD, Ma X, Wang L, Alonzo TA, Rubnitz JE, Pounds S, Klco JM. A new genomic framework to categorize pediatric acute myeloid leukemia. Nature genetics 2024. PMID: 38212634

Temple WC, Nix MA, Naik A, Izgutdina A, Huang BJ, Wicaksono G, Phojanakong P, Serrano JAC, Young EP, Ramos E, Salangsang F, Steri V, Xirenayi S, Hermiston M, Logan AC, Stieglitz E, Wiita AP. Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies. Journal for immunotherapy of cancer 2023. PMID: 38007238

Mandal K, Wicaksono G, Yu C, Adams JJ, Hoopmann MR, Temple WC, Izgutdina A, Escobar BP, Gorelik M, Ihling CH, Nix MA, Naik A, Xie WH, Hübner J, Rollins LA, Reid SM, Ramos E, Kasap C, Steri V, Serrano JAC, Salangsang F, Phojanakong P, McMillan M, Gavallos V, Leavitt AD, Logan AC, Rooney CM, Eyquem J, Sinz A, Huang BJ, Stieglitz E, Smith CC, Moritz RL, Sidhu SS, Huang L, Wiita AP. Structural surfaceomics reveals an AML-specific conformation of integrin ß2 as a CAR T cellular therapy target. Nature cancer 2023. PMID: 37904046

Meyer LK, Huang I, Huang BJ, Chung JH, Pawar A, Hermiston ML, Loh ML, Ohgami RS, Ruiz-Cordero R, Bhargava P, Marinoff AE. Hemophagocytic lymphohistiocytosis and clonally related T-cell malignancies in a pediatric patient. Pediatric blood & cancer 2023. PMID: 37702960

Chen PY, Huang BJ, Harris M, Boone C, Wang W, Carias H, Mesiona B, Mavrici D, Kohler AC, Bollag G, Zhang C, Zhang Y, Shannon K. Structural and functional analyses of a germline KRAS T50I mutation provide insights into Raf activation. JCI insight 2023. PMID: 37681415

Levinson A, Tjoa K, Huang BJ, Meyer LK, Kim MO, Brady SW, Zhang J, Shannon KM, Wandler A. Opposing Effects of KDM6A and JDP2 on Glucocorticoid Sensitivity in T-ALL. Blood advances 2023. PMID: 36897249

Perkins IU, Tan SY, McCalmont TH, Chou PM, Mully TW, Gerami P, Pomerantz JH, Reyes-Múgica M, Balkin DM, Kruse LL, Huang B, Reichek JL, Gangopadhyay N, Chiosea S, Green JR, Chamlin SL, Frieden IJ, Bastian BC, Yeh I. Melanoma in infants, caused by a gene fusion involving the anaplastic lymphoma kinase (ALK). Pigment cell & melanoma research 2023. PMID: 37475109

Umeda M, Ma J, Westover T, Ni Y, Song G, Maciaszek JL, Rusch M, Rahbarinia D, Foy S, Huang BJ, Walsh MP, Kumar P, Liu Y, Fan Y, Wu G, Baker SD, Ma X, Wang L, Rubnitz JE, Pounds S, Klco JM. Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis. Research square 2023. PMID: 37398194

Huang BJ, Shannon K. NFIA-ETO2, TP53, and erythroid leukemogenesis. Blood 2023. PMID: 37140954

Marinoff AE, Aaronson K, Agrawal AK, Braun BS, Golden C, Huang BJ, Michlitsch J, Southworth E, Thrall A, Vo KT, Stieglitz E. Venetoclax in combination with chemotherapy as treatment for pediatric advanced hematologic malignancies. Pediatric blood & cancer 2023. PMID: 37036306

Liu Y, Klein J, Bajpai R, Dong L, Tran Q, Kolekar P, Smith JL, Ries RE, Huang BJ, Wang YC, Alonzo TA, Tian L, Mulder HL, Shaw TI, Ma J, Walsh MP, Song G, Westover T, Autry RJ, Gout AM, Wheeler DA, Wan S, Wu G, Yang JJ, Evans WE, Loh M, Easton J, Zhang J, Klco JM, Meshinchi S, Brown PA, Pruett-Miller SM, Ma X. Etiology of oncogenic fusions in 5,190 childhood cancers and its clinical and therapeutic implication. Nature communications 2023. PMID: 37019972

Ferrato MH, Marsh AG, Franke KR, Huang BJ, Kolb EA, DeRyckere D, Grahm DK, Chandrasekaran S, Crowgey EL. Machine learning classifier approaches for predicting response to RTK-type-III inhibitors demonstrate high accuracy using transcriptomic signatures and ex vivo data. Bioinformatics advances 2023. PMID: 37250111

Meyer L, Huang I, Huang B, Steen E, Chung JH, Pawar A, Hermiston M, Ohgami R, Ruiz-Cordero R, Bhargava P, Marinoff A. Pediatric Blood & Cancer Clonally Related T-cell Malignancies and Hemophagocytic Lymphohistiocytosis in a Pediatric Patient 2023. PMID:

Farrar JE, Smith JL, Othus M, Huang BJ, Wang YC, Ries R, Hylkema T, Pogosova-Agadjanyan EL, Challa S, Leonti A, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb EA, Ma X, Stirewalt DL, Alonzo TA, Meshinchi S. Long Noncoding RNA Expression Independently Predicts Outcome in Pediatric Acute Myeloid Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2023. PMID: 36795987

Farrar JE, Smith JL, Othus M, Huang BJ, Wang Y-C, Ries RE, Hylkema TA, Pogosova-Agadjanyan EL, Challa S, Leonti AR, Shaw TI, Triche TJ, Gamis AS, Aplenc R, Kolb AE, Ma X, Stirewalt D, Alonzo TA, Meshinchi S. Blood. American Society of Hematology A Robust Long Non-Coding RNA Expression Classifier for Risk Stratification in Pediatric AML 2022. PMID:

Lamble AJ, Ries RE, Alonzo TA, Wang Y-C, Farrar JE, Huang BJ, Kutny MA, Pollard JA, Aplenc R, Gamis AS, Kolb EA, Cooper TM, Meshinchi S. Blood. American Society of Hematology Expanding the High-Risk Definition for Children with Newly Diagnosed Acute Myeloid Leukemia 2022. PMID:

Mandal, Kamal; Wicaksono, Gianina; Yu, Clinton; Adams, Jarrett J.; Hoopmann, Michael R.; Temple, William C.; Escobar, Bonell Patino; Gorelik, Maryna; Ihling, Christian; Nix, Matthew A.; Naik, Akul; Ramos, Emilio; Kasap, Corynn; Steri, Veronica; Serrano, Juan Antonio Camara; Salangsang, Fernando; Phojanakong, Paul; McMillan, Melanie; Gavallos, Victor; Leavitt, Andrew D.; Sinz, Andrea; Huang, Benjamin J.; Stieglitz, Elliot; Smith, Catherine; Moritz, Robert L.; Sidhu, Sachdeva S.; Huang, Lan; Wiita, Arun P. Blood. American Society of Hematology Structural Surfaceomics Reveals an AML-Specific Conformation of Integrin-β2 As an Immunotherapeutic Target 2022. PMID:

Meyer LK, Roy RP, Pölönen P, Elsayed A, Huang BJ, Kimura S, Delgado-Martin C, Vincent TL, Ryan T, Wood BL, Chen Z, Liu Y, Zhang J, Horton TM, Loh ML, Devidas M, Raetz EA, Hayashi RJ, Winter SS, Dunsmore KP, Hunger SP, Pounds SB, Hermiston ML, Yang JJ, Mullighan CG, Teachey DT, Olshen AB. Blood. American Society of Hematology A Transcriptional Classifier Identifies Pediatric T-Cell Acute Lymphoblastic Leukemias at High Risk for End of Induction Minimal Residual Disease 2022. PMID:

Obermayer A, Yao S, Smith JL, Ries RE, Wang Y-C, Farrar JE, Furlan SN, Triche R, Ma X, Huang BJ, Wang X, Meshinchi S, Shaw TI. Blood. American Society of Hematology Transcriptome Analysis and Machine Learning Prioritize Therapeutic Strategies for High-Risk Pediatric AML Patients of the KMT2A-Fusion Subgroup 2022. PMID:

Levinson A, Tjoa K, Huang BJ, Meyer LK, Brady SW, Zhang J, Shannon KM, Wandler A. Blood. American Society of Hematology. 140: 5973-5974. 15 Nov 2022 Opposing Effects of KDM6A and JDP2 on Glucocorticoid Sensitivity in T-ALL 2022. PMID:

Le Q, Hadland B, Smith JL, Leonti A, Huang BJ, Ries R, Hylkema TA, Castro S, Tang TT, McKay CN, Perkins L, Pardo L, Sarthy J, Beckman AK, Williams R, Idemmili R, Furlan S, Ishida T, Call L, Srivastava S, Loeb AM, Milano F, Imren S, Morris SM, Pakiam F, Olson JM, Loken MR, Brodersen L, Riddell SR, Tarlock K, Bernstein ID, Loeb KR, Meshinchi S. CBFA2T3-GLIS2 model of pediatric acute megakaryoblastic leukemia identifies FOLR1 as a CAR T cell target. The Journal of clinical investigation 2022. PMID: 36136600

Huang BJ, Smith JL, Farrar JE, Wang YC, Umeda M, Ries RE, Leonti AR, Crowgey E, Furlan SN, Tarlock K, Armendariz M, Liu Y, Shaw TI, Wei L, Gerbing RB, Cooper TM, Gamis AS, Aplenc R, Kolb EA, Rubnitz J, Ma J, Klco JM, Ma X, Alonzo TA, Triche T, Meshinchi S. Integrated stem cell signature and cytomolecular risk determination in pediatric acute myeloid leukemia. Nature communications 2022. PMID: 36123353

Smith TH, Higgins JE, Lo FY, Hipp MJ, Valentine CC, Leonti AR, Ries RE, Meshinchi S, Huang BJ, Salk JJ. Cancer Research Longitudinal monitoring of pediatric acute myeloid leukemia using duplex sequencing of patient-specific panels reveals ultra-low frequency MRD that marks persistent carcinogenesis and complex clonal evolution 2022. PMID:

Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Tian L, Liu Y, Chen X, Kolekar P, Tran Q, Foy SG, Maciaszek JL, Kleist AB, Leonti AR, Ju B, Easton J, Wu H, Valentine V, Valentine MB, Liu YC, Ries RE, Smith JL, Parganas E, Iacobucci I, Hiltenbrand R, Miller J, Myers JR, Rampersaud E, Rahbarinia D, Rusch M, Wu G, Inaba H, Wang YC, Alonzo TA, Downing JR, Mullighan CG, Pounds S, Babu MM, Zhang J, Rubnitz JE, Meshinchi S, Ma X, Klco JM. Integrated genomic analysis identifies UBTF tandem duplications as a recurrent lesion in pediatric acute myeloid leukemia. 2022. PMID: 35176137

Meyer LK, Delgado-Martin C, Sharp PP, Huang BJ, McMinn D, Vincent TL, Ryan T, Horton TM, Wood BL, Teachey DT, Taunton J, Kirk CJ, Hermiston ML. Inhibition of the Sec61 translocon overcomes cytokine-induced glucocorticoid resistance in T-cell acute lymphoblastic leukaemia. 2022. PMID: 35434798

Huang BJ, Smith J, Wang J, Taghizadeh K, Leonti AR, Ries RE, Liu Y, Kolekar P, Tarlock K, Gerbing RB, Crowgey E, Furlan SN, Shaw TI, Hagiwara K, Wei L, Cooper T, Gamis AS, Aplenc R, Kolb EA, Farrar JE, Triche TJ, Alonzo T, Ma X, Meshinchi S. CBFB-MYH11 Fusion Transcripts Distinguish Acute Myeloid Leukemias with Distinct Molecular Landscapes and Outcomes. Blood advances 2021. PMID: 34547772

Umeda M, Ma J, Huang BJ, Hagiwara K, Westover T, Abdelhamed S, Barajas JM, Thomas ME, Walsh MP, Song G, Tian L, Liu Y, Chen X, Kolekar P, Tran Q, Foy S, Maciaszek JL, Kleist AB, Leonti AR, Ju B, Easton J, Wu H, Valentine V, Valentine M, Liu Y-C, Ries RE, Smith JL, Parganas E, Iacobucci I, Hiltenbrand R, Miller J, Myers J, Rampersaud E, Rahbarinia D, Rusch M, Wu G, Inaba H, Wang Y-C, Alonzo TA, Downing JR, Mullighan CG, Pounds SB, Babu MM, Zhang J, Rubnitz JE, Meshinchi S, Ma X, Klco JM. Blood. American Society of Hematology Integrated Genomic Analysis Identifies UBTF Tandem Duplications As a Subtype-Defining Lesion in Pediatric Acute Myeloid Leukemia 2021. PMID:

Buteyn NJ, Burke CG, Smith JL, Ries RE, Leonti AR, Shaw TI, Huang BJ, Alonzo TA, Furlan SN, Farrar JE, Meshinchi S, Triche TJ. Blood. American Society of Hematology EZH2-Mediated MHC Class II Silencing Drives Immune Evasion in AML with t(16;21) FUS-ERG 2021. PMID:

Huang BJ, Smith JL, Shaw TI, Furlan SN, Ries RE, Leonti AR, Crowgey EL, Wei L, Farrar JE, Triche T, Ma X, Le Q, Meshinchi S. Blood. American Society of Hematology Integrated Transcriptomics and Proteomics Identifies Therapeutic Targets in Pediatric Acute Myeloid Leukemia 2021. PMID:

Le Q, Smith JL, Tang TT, Castro S, Nourigat-Mckay C, Perkins L, Huang BJ, Ries RE, Leonti AR, Hylkema TA, Pardo L, Abrahams C, Bedard K, Molina A, Eidenschink Brodersen L, Loken MR, Meshinchi S. Blood. American Society of Hematology Targeting FOLR1 in High-Risk CBF2AT3-GLIS2 AML with Stro-002 FOLR1-Directed Antibody-Drug Conjugate 2021. PMID:

Smith JL, Ries RE, Wang Y-C, Leonti AR, Alonzo TA, Gamis AS, Aplenc R, Kolb AE, Huang BJ, Ma X, Shaw TI, Meshinchi S. Blood. American Society of Hematology ETS Family Transcription Factor Fusions in Childhood AML: Distinct Expression Networks and Clinical Implications 2021. PMID:

Meyer LK, Roy R, Huang BJ, Delgado-Martin C, Vincent TL, Wood BL, Liu Y, Zhang J, Mullighan CG, Horton TM, Loh ML, Devidas M, Raetz EA, Hayashi RJ, Winter SS, Dunsmore KP, Hunger S, Teachey DT, Olshen AB Hermiston ML. Journal of Clinical Oncology Targeted gene expression classifier identifies pediatric T-cell acute lymphoblastic leukemia (T-ALL) patients at high risk for end induction minimal residual disease positivity 2021. PMID:

Meyer L, Roy RP, Huang B, Kimura S, Polonen P, Delgado-Martin C, Vincent T, Ryan T, Wood B, Liu Y, Zhang J, Mullighan C, Horton T, Loh M, Devidas M, Raetz E, Hayashi R, Winter S, Dunsmore K, Hunger S, Teachey D, Hermiston M, Olshen AB. Leukemia Research A Targeted Gene Expression Classifier Identifies Pediatric T-ALL Patient at High Risk for End Induction Minimal Residual Disease Positivity 2022. PMID:

Peretz CAC, McGary LHF, Kumar T, Jackson H, Jacob J, Durruthy-Durruthy R, Levis MJ, Perl A, Huang BJ, Smith CC. Single-cell DNA sequencing reveals complex mechanisms of resistance to quizartinib. Volume 5 of Issue 5. Blood advances 2021. PMID: 33666651

Higgins J, Lo FY, Hipp MJ, Valentine CC, Williams LN, Leonti AR, Ries RE, Radich JP, Meshinchi S, Huang BJ, Salk JJ. Blood. American Society of Hematology Duplex Sequencing with Patient-Specific Hybrid Capture Panels Reveals Ultra-Low Frequency Measurable Residual Disease in Pediatric Acute Myeloid Leukemia 2020. PMID:

Huang BJ, Smith JL, Ries RE, Leonti AR, Crowgey EL, Furlan SN, Shaw T, Wei L, Wang Y-C, Gerbing RB, Alonzo TA, Cooper TM, Kolb EA, Ma X, Farrar JE, Triche TJ, Meshinchi S. Blood. American Society of Hematology Integrated Stem Cell Signature and Cytomolecular Risk Determination in Pediatric Acute Myeloid Leukemia 2020. PMID:

Huang BJ, Wang X, Harris M, Wandler A, Hwang E, Burgess MR, Li Q, Severson P, Powell B, Kolb EA, Meshinchi S, Taylor BS, Bollag G, Shannon KM. Blood. American Society of Hematology Co-Targeting BET Bromodomain Proteins and Aberrant Signaling in AML 2020. PMID:

Ries RE, Triche TJ, Smith JL, Leonti AR, Alonzo TA, Farrar JE, Chen X, Liu Y, Shaw T, Huang BJ, Wang Y-C, Gerbing RB, Hirsch BA, Raimondi SC, Gamis AS, Aplenc R, Zhang J, Kolb EA, Ma X, Meshinchi S. Blood. American Society of Hematology Genome and Transcriptome Profiling of Monosomy 7 AML Defines Novel Risk and Therapeutic Cohorts 2020. PMID:

Pucciarelli D, Angus SP, Huang B, Zhang C, Nakaoka HJ, Krishnamurthi G, Bandyopadhyay S, Clapp DW, Shannon K, Johnson GL, Nakamura JL. Nf1-Mutant Tumors Undergo Transcriptome and Kinome Remodeling after Inhibition of either mTOR or MEK. Molecular cancer therapeutics 2020. PMID: 32847978

Zambetti NA, Firestone AJ, Remsberg JR, Huang BJ, Wong JC, Long AM, Predovic M, Suciu RM, Inguva A, Kogan SC, Haigis KM, Cravatt BF, Shannon K. Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice. Blood 2020. PMID: 32219446

Wandler AM, Huang BJ, Craig JW, Hayes K, Yan H, Meyer LK, Scacchetti A, Monsalve G, Dail M, Li Q, Wong JC, Weinberg O, Hasserjian RP, Kogan SC, Jonsson P, Yamamoto K, Sampath D, Nakitandwe J, Downing JR, Zhang J, Aster JC, Taylor BS, Shannon K. Loss of glucocorticoid receptor expression mediates in vivo dexamethasone resistance in T-cell acute lymphoblastic leukemia. Leukemia 2020. PMID: 32066867

Meyer LK, Huang BJ, Delgado-Martin C, Roy RP, Hechmer A, Wandler AM, Vincent TL, Fortina P, Olshen AB, Wood BL, Horton TM, Shannon KM, Teachey DT, Hermiston ML. Glucocorticoids paradoxically facilitate steroid resistance in T cell acute lymphoblastic leukemias and thymocytes. The Journal of clinical investigation 2020. PMID: 31687977

Huang BJ, Wandler AM, Meyer LK, Dail M, Daemen A, Sampath D, Li Q, Wang X, Wong JC, Nakitandwe J, Downing JR, Zhang J, Taylor BS, Shannon K. Convergent genetic aberrations in murine and human T lineage acute lymphoblastic leukemias. PLoS genetics 2019. PMID: 31199785

Meyer LK, Delgado-Martin C, Roy R, Huang BJ, Vincent T, Olshen A, Wood BL, Liu Y, Zhang J, Mullighan CG, Horton TM, Loh ML, Devidas M, Raetz EA, Hayashi RJ, Winter S, Dunsmore KP, Hunger S, Teachey DT, Hermiston HL. Journal of Clinical Oncology. American Society of Clinical Oncology Gene expression signature associated with in vitro dexamethasone resistance and post-induction minimal residual disease in pediatric T-cell acute lymphoblastic leukemia 2019. PMID:

Meyer LK, Huang B, Roy R, Hechmer A, Wandler A, Delgado-Martin C, Olshen AB, Horton TM, Teachey DT, Shannon KM, Hermiston ML. Blood. American Society of Hematology Glucocorticoids Paradoxically Induce Intrinsic Steroid Resistance through a STAT5-Mediated Survival Mechanism in T-Cell Acute Lymphoblastic Leukemia 2018. PMID:

Meyer LK, Delgado-Martin C, Huang BJ, Wandler AM, Horton TM, Teachey DT, Shannon KM, Hermiston ML. British Journal of Haematology Glucocorticoids paradoxically induce steroid resistance through a STAT5-mediated survival mechanism in T-cell acute lymphoblastic leukemia/lymphoma 2018. PMID:

Delgado-Martin C, Meyer LK, Huang BJ, Shimano KA, Zinter MS, Nguyen JV, Smith GA, Taunton J, Winter SS, Roderick JR, Kelliher MA, Horton TM, Wood BL, Teachey DT, Hermiston ML. JAK/STAT pathway inhibition overcomes IL7-induced glucocorticoid resistance in a subset of human T-cell acute lymphoblastic leukemias. Leukemia 2017. PMID: 28484265

Burgess MR, Hwang E, Mroue R, Bielski CM, Wandler AM, Huang BJ, Firestone AJ, Young A, Lacap JA, Crocker L, Asthana S, Davis EM, Xu J, Akagi K, Le Beau MM, Li Q, Haley B, Stokoe D, Sampath D, Taylor BS, Evangelista M, Shannon K. KRAS Allelic Imbalance Enhances Fitness and Modulates MAP Kinase Dependence in Cancer. Cell 2017. PMID: 28215705

Huang B, Hwang E, Wandler AM, Powell B, Bollag G, Shannon K. Blood. American Society of Hematology Response and Resistance to Bromodomain Inhibition in AML Driven By Hyperactive Ras Signaling 2016. PMID:

Wandler AM, Huang B, Scacchetti A, Craig J, Yan H, Monsalve G, Li Q, Dail M, Wong JC, Nakitandwe J, Weinberg O, Hasserjian RP, Kogan SC, Sampath D, Downing JR, Yamamoto K, Taylor BS, Aster JC, Zhang J, Shannon K. Blood. American Society of Hematology Resistant T-Cell Acute Lymphoblastic Leukemias That Emerge after In Vivo Treatment with Dexamethasone Frequently Down-Regulate Glucocorticoid Receptor Protein Expression 2016. PMID:

Huang B, Dvorak CC, Wahlstrom J, Hwang J, Long-Boyle JR, Cowan MJ, Horn BN. Blood. American Society of Hematology Risk Factors for Graft Failure with Busulfan/Fludarabine-Based Conditioning in Children Undergoing Allogeneic Hematopoietic Cell Transplantation for Nonmalignant Disorders 2014. PMID:

Dail M, Li Q, McDaniel A, Wong J, Akagi K, Huang B, Kang HC, Kogan SC, Shokat K, Wolff L, Braun BS, Shannon K. Mutant Ikzf1, KrasG12D, and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents. Proceedings of the National Academy of Sciences of the United States of America 2010. PMID: 20194733

Li Q, Haigis K, McDaniel A, Huang B, Miller M, Shieh A, Kogan S, Wolff L, Jacks T, Shannon K. Blood. American Society of Hematology Expressing N-Ras(G12D) from the endogenous promoter induces myeloproliferative disease (MPD) and cooperates with retroviral insertional mutagenesis (RIM) to generate acute myeloid leukemia (AML) 2007. PMID: