Emmanuelle Waubant, MD, PhD

Dr Waubant trained as a neurologist in Toulouse, France. She continued her training as a neuroimmunology fellow in Dr Stephen Hauser’s UCSF laboratory, focusing on matrix metalloproteinases (MMP) and their tissue inhibitors (TIMP), and their role in migration of lymphocytes through equivalents of the blood-brain barrier. In 1994, Dr Waubant returned to Toulouse to complete her 2-year junior faculty/chief residency in neurology. Dr Waubant later returned as a clinical research fellow at the UCSF MS Center with Dr Donald Goodkin. During that 3-year period, she furthered her in vitro MMP work to the study in the human disease that helped to understand the role of MMP-9 and TIMP-1 in patients with MS and their relationship to disease activity. After completing her clinical research training at the UCSF MS center, Dr Waubant returned to France to lead a clinical research center at Salpetriere Hospital in Paris for 2 years. She returned to the UCSF MS center in September 2001 as a faculty. She is also the Race to Erase MS Medical Director and coordinates clinical research collaborations between 6 American MS Centers of Excellence. With the support of the National MS Society, she has started a regional pediatric MS clinic at UCSF in January 2006 that she directs and has since seen over 350 patients with pediatric MS or related disorders. She is the editor of the first text book on Pediatric MS and related disorders. Dr Waubant is At-large Board Director and on the program committee of the the American Committee on Treatment and Research in MS and the Chair of the U.S. Pediatric MS Steering Committee. She is also chairing the international Clinical Trial Task Force for pediatric MS.
Dr Waubant’s specific interests include the translation of promising agents from the bench to the bedside, understanding factors that predict the response to MS therapies, and risk factors for pediatric MS susceptibility and disease modification. Currently, she is the co-lead investigator for a trial of vitamin D in relapsing-remitting MS sponsored by the NMSS and is the recipient of a large multicenter NIH grant to study risk factors in pediatric MS and their interactions. Dr. Waubant is also a very active mentor for junior investigators.
Honors and Awards
  • Fellow of the American Neurological Association, American Neurological Association, 2013
  • Nominated for the Outstanding Faculty Mentorship Award, UCSF, 2013
  • Nominated for the Outstanding Faculty Mentorship Award, UCSF, 2012
  • Nominated for the Outstanding Faculty Mentorship Award, UCSF, 2011
  • Fellow of the American Academy of Neurology, American Academy of Neurology, 2010
  • Selected one of the "Best Doctors in America", Best Doctors in America, 2010
  • Nominated for the Chancellor's Award for the Advancement of Women, UCSF, 2010
  • Nominated for the Outstanding Faculty Mentorship Award, UCSF, 2010
  • Nominated for the Outstanding Faculty Mentorship Award, UCSF, 2008
Websites
  1. Wilson E, Meeks HD, Barney BJ, Waltz M, Canenguez K, Casper TC, Rose JW, Rodriguez M, Tillema JM, Chitnis T, Gorman MP, Rensel M, Abrams AW, Krupp LB, Lotze TE, Fisher KS, Shukla NM, Schreiner TL, Mar SS, Waubant E, Virupakshaiah A, Wheeler YS, Ness JM, Benson LA, as the United States Network of Pediatric Multiple Sclerosis Centers. Epidemiology and Impact of Social Hardships in Children With Multiple Sclerosis in the United States. Neurology 2024. PMID: 39531607


  2. Jank L, Singh SS, Lee J, Dhukhwa A, Siavoshi F, Joshi D, Minney V, Gupta K, Ghimire S, Deme P, Schoeps VA, Soman K, Ladakis D, Smith M, Borkowski K, Newman J, Baranzini SE, Waubant EL, Fitzgerald KC, Mangalam A, Haughey N, Kornberg M, Chamling X, Calabresi PA, Bhargava P. Restoring the Multiple Sclerosis Associated Imbalance of Gut Indole Metabolites Promotes Remyelination and Suppresses Neuroinflammation. bioRxiv : the preprint server for biology 2024. PMID: 39554063


  3. Hua LH, Solomon AJ, Tenembaum S, Scalfari A, Rovira À, Rostasy K, Newsome SD, Marrie RA, Magyari M, Kantarci O, Hemmer B, Hemingway C, Harnegie MP, Graves JS, Cohen JA, Bove R, Banwell B, Corboy JR, Waubant E. Differential Diagnosis of Suspected Multiple Sclerosis in Pediatric and Late-Onset Populations: A Review. JAMA neurology 2024. PMID: 39283621


  4. Schoeps VA, Bhargava P, Virupakshaiah A, Ladakis DC, Moseley C, Chong J, Aaen G, Graves JS, Benson L, Gorman MP, Rensel M, Abrams A, Mar S, Lotze TE, Chitnis T, Waldman A, Krupp L, Rodriguez M, Tillema JM, Rose J, Schreiner T, Qureshi F, Peterson S, Barcellos LF, Casper TC, Newman J, Borkowski K, Waubant E, US Network of Pediatric MS Centers. Distinct plasma lipids predict axonal injury and multiple sclerosis activity. Journal of neurology, neurosurgery, and psychiatry 2024. PMID: 39266284


  5. Jensen SKG, Camposano S, Berens A, Waltz M, Krupp LB, Charvet L, Belman AL, Aaen GS, Benson LA, Candee M, Casper TC, Chitnis T, Graves J, Wheeler YS, Kahn I, Lotze TE, Mar SS, Rensel M, Rodriguez M, Rose JW, Rubin JP, Tillema JM, Waldman AT, Weinstock-Guttman B, Barcellos LF, Waubant E, Gorman MP, US Network of Pediatric Multiple Sclerosis Centers. Early Adversity and Socioeconomic Factors in Pediatric Multiple Sclerosis: A Case-Control Study. Neurology(R) neuroimmunology & neuroinflammation 2024. PMID: 39146511


  6. Mirza AI, Zhu F, Knox N, Black LJ, Daly A, Bonner C, Van Domselaar G, Bernstein CN, Marrie RA, Hart J, Yeh EA, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H. Mediterranean diet and associations with the gut microbiota and pediatric-onset multiple sclerosis using trivariate analysis. Communications medicine 2024. PMID: 39030379


  7. Jing J, Zhang Z, Su L, Gao C, Guo A, Liu X, Wang H, Zhang X, Liu Y, Comi G, Waubant E, Shi FD, Tian DC. Central vein sign and trigeminal lesions of multiple sclerosis visualised by 7T MRI. Journal of neurology, neurosurgery, and psychiatry 2024. PMID: 38453475


  8. Pilloni G, Casper TC, Mar S, Ness J, Schreiner T, Waltz M, Waubant E, Weinstock-Guttman B, Wheeler Y, Krupp L, Charvet L. Increased intraindividual variability (IIV) in reaction time is the earliest indicator of cognitive change in MS: A two-year observational study. International journal of clinical and health psychology : IJCHP 2024. PMID: 39105175


  9. Moseley CE, Virupakshaiah A, Forsthuber TG, Steinman L, Waubant E, Zamvil SS. MOG CNS Autoimmunity and MOGAD. Neurology(R) neuroimmunology & neuroinflammation 2024. PMID: 38996203


  10. Virupakshaiah A, Schoeps VA, Race J, Waltz M, Sharayah S, Nasr Z, Moseley CE, Zamvil SS, Gaudioso C, Schuette A, Casper TC, Rose J, Flanagan EP, Rodriguez M, Tillema JM, Chitnis T, Gorman MP, Graves JS, Benson LA, Rensel M, Abrams A, Krupp L, Lotze TE, Aaen G, Wheeler Y, Schreiner T, Waldman A, Chong J, Mar S, Waubant E. Predictors of a relapsing course in myelin oligodendrocyte glycoprotein antibody-associated disease. Journal of neurology, neurosurgery, and psychiatry 2024. PMID: 38964848


  11. Mohan SD, Peterson S, Brenton JN, Carmichael SL, Virupakshaiah A, Rodriguez M, Tillema JM, Mar S, Rensel MR, Abrams A, Chitnis T, Benson L, Gorman M, Lotze T, Shukla N, Graves J, Aaen G, Casper TC, Waubant E. Association of nutritional intake with clinical and imaging activity in pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2024. PMID: 39078111


  12. Schoeps VA, Virupakshaiah A, Waubant E. Unveiling the Performance of Proposed MOGAD Diagnostic Criteria. Neurology 2024. PMID: 38870485


  13. Nasr Z, Casper TC, Waltz M, Virupakshaiah A, Lotze T, Shukla N, Chitnis T, Gorman M, Benson LA, Rodriguez M, Tillema JM, Krupp L, Schreiner T, Mar S, Rensel M, Rose J, Liu C, Guye S, Manlius C, Waubant E, U.S. Network of Pediatric Multiple Sclerosis Centers. Clinical and magnetic resonance imaging outcomes in pediatric-onset MS patients on fingolimod and ocrelizumab. Multiple sclerosis and related disorders 2024. PMID: 38838422


  14. Virupakshaiah A, Moseley CE, Elicegui S, Gerwitz LM, Spencer CM, George E, Shah M, Cree BAC, Waubant E, Zamvil SS. Life-Threatening MOG Antibody-Associated Hemorrhagic ADEM With Elevated CSF IL-6. Neurology(R) neuroimmunology & neuroinflammation 2024. PMID: 38630950


  15. Bitarafan S, Zhu F, Mirza A, Bernstein CN, Van Domselaar G, Marrie RA, Yeh EA, Zhao Y, Banwell B, Waubant E, Tremlett H. Assessment of dietary intake and its inflammatory potential in persons with pediatric-onset multiple sclerosis. Multiple sclerosis and related disorders 2024. PMID: 38604004


  16. Ziaei A, Solomon O, Casper TC, Waltz M, Weinstock-Guttman B, Aaen G, Wheeler Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Waldman AT, Krupp L, James JA, Hart J, Barcellos LF, Waubant E. Gene-environment interactions: Epstein-Barr virus infection and risk of pediatric-onset multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2024. PMID: 38332747


  17. George E, Russ JB, Validrighi A, Early H, Mamlouk MD, Glenn OA, Francisco CM, Waubant E, Lindan C, Li Y. Clinical and Imaging Findings in Children with Myelin Oligodendrocyte Glycoprotein Antibody Associated Disease (MOGAD): From Presentation to Relapse. AJNR. American journal of neuroradiology 2024. PMID: 38176731



  18. Zhu F, Zhao Y, Arnold DL, Bar-Or A, Bernstein CN, Bonner C, Graham M, Hart J, Knox N, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Banwell B, Waubant E, Tremlett H, US Network of Pediatric MS Centers, the Canadian Pediatric Demyelinating Disease Network. A cross-sectional study of MRI features and the gut microbiome in pediatric-onset multiple sclerosis. Annals of clinical and translational neurology 2023. PMID: 38130033


  19. Nasr Z, Virupakshaiah A, Schoeps VA, Cherbuin N, Casper TC, Waltz M, Hart J, Rodriguez M, Gorman MP, Benson LA, Chitnis T, Rensel M, Abrams A, Krupp L, Waldman AT, Lotze T, Aaen GS, Mar S, Schreiner T, Wheeler Y, Rose J, Shukla NM, Barcellos LF, Lucas R, Waubant E. Gene-environment interactions and risk of pediatric-onset multiple sclerosis associated with time spent outdoors. Multiple sclerosis and related disorders 2023. PMID: 38141560


  20. Schoeps VA, Zhou X, Horton MK, Zhu F, McCauley KE, Nasr Z, Virupakshaiah A, Gorman MP, Benson LA, Weinstock-Guttman B, Waldman A, Banwell BL, Bar-Or A, Marrie RA, van Domselaar G, O'Mahony J, Mirza AI, Bernstein CN, Yeh EA, Casper TC, Lynch SV, Tremlett H, Baranzini S, Waubant E, US Network of Pediatric MS Centers. Short-chain fatty acid producers in the gut are associated with pediatric multiple sclerosis onset. Annals of clinical and translational neurology 2023. PMID: 37955284


  21. Sacco S, Virupakshaiah A, Papinutto N, Schoeps VA, Akula A, Zhao H, Arona J, Stern WA, Chong J, Hart J, Zamvil SS, Sati P, Henry RG, Waubant E. Susceptibility-based imaging aids accurate distinction of pediatric-onset MS from myelin oligodendrocyte glycoprotein antibody-associated disease. Multiple sclerosis (Houndmills, Basingstoke, England) 2023. PMID: 37897254


  22. Rutatangwa A, Aaen G, Krysko KM, Belman A, Benson LA, Chitnis T, Gorman M, Goyal M, Graves JS, Wheeler Y, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Rodriguez M, Rose J, Schreiner T, Tillema JM, Weinstock-Guttman B, Waltz M, Casper TC, Waubant E, U.S. Network of Pediatric MS Centers. Characteristics and predictors of disease course in children initially presenting with ADEM. Multiple sclerosis and related disorders 2023. PMID: 39491412


  23. Solomon AJ, Arrambide G, Brownlee WJ, Flanagan EP, Amato MP, Amezcua L, Banwell BL, Barkhof F, Corboy JR, Correale J, Fujihara K, Graves J, Harnegie MP, Hemmer B, Lechner-Scott J, Marrie RA, Newsome SD, Rocca MA, Royal W, Waubant EL, Yamout B, Cohen JA. Differential diagnosis of suspected multiple sclerosis: an updated consensus approach. The Lancet. Neurology 2023. PMID: 37479377


  24. Abdelhak A, Petermeier F, Benkert P, Schädelin S, Oechtering J, Maleska Maceski A, Kabesch M, Geis T, Laub O, Leipold G, Gobbi C, Zecca C, Green A, Tumani H, Willemse E, Wiendl H, Granziera C, Kappos L, Leppert D, Waubant E, Wellmann S, Kuhle J. Serum neurofilament light chain reference database for individual application in paediatric care: a retrospective modelling and validation study. The Lancet. Neurology 2023. PMID: 37524100


  25. Virupakshaiah A, Ladakis DC, Nourbakhsh B, Bhargava P, Dilwali S, Schoeps V, Borkowski K, Newman JW, Waubant E. Several serum lipid metabolites are associated with relapse risk in pediatric-onset multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2023. PMID: 37199529


  26. Malani Shukla N, Casper TC, Ness J, Wheeler Y, Chitnis T, Lotze T, Gorman M, Benson L, Weinstock-Guttmann B, Aaen G, Rodriguez M, Tillema JM, Krupp L, Schreiner T, Mar S, Goyal M, Rensel M, Abrams A, Rose J, Waltz M, Liu T, Manlius C, Waubant E, U.S. Network of Pediatric Multiple Sclerosis Centers. Demographic Features and Clinical Course of Patients With Pediatric-Onset Multiple Sclerosis on Newer Disease-Modifying Treatments. Pediatric neurology 2023. PMID: 37348193


  27. Cassard SD, Fitzgerald KC, Qian P, Emrich SA, Azevedo CJ, Goodman AD, Sugar EA, Pelletier D, Waubant E, Mowry EM. High-dose vitamin D3 supplementation in relapsing-remitting multiple sclerosis: a randomised clinical trial. EClinicalMedicine 2023. PMID: 37125397


  28. Ziaei A, Nasr Z, Hart J, Francisco C, Rutatangwa A, Leppert D, Kuhle J, Flanagan E, Waubant E. High serum neurofilament levels are observed close to disease activity events in pediatric-onset MS and MOG antibody-associated diseases. Multiple sclerosis and related disorders 2023. PMID: 37031551


  29. Van Haren KP, Cunanan K, Awani A, Gu M, Pe?a D, Chromik LC, Pova?an M, Rossi NC, Goodman J, Sundaram V, Winterbottom J, Raymond GV, Cowan T, Enns GM, Waubant E, Steinman L, Barker PB, Spielman D, Fatemi A. A Phase 1 Study of Oral Vitamin D3 in Boys and Young Men With X-Linked Adrenoleukodystrophy. Neurology. Genetics 2023. PMID: 37090939


  30. Schreiner T, Wilson-Murphy M, Mendelt-Tillema J, Waltz M, Codden R, Benson L, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Roalstad S, Rodriguez M, Rose J, Shukla N, Waubant E, Wheeler Y, Casper TC, Chitnis T. Characteristics of pediatric patients with multiple sclerosis and related disorders infected with SARS-CoV-2. Multiple sclerosis (Houndmills, Basingstoke, England) 2023. PMID: 36960480


  31. Bhise V, Waltz M, Casper TC, Aaen G, Benson L, Chitnis T, Gorman M, Goyal MS, Wheeler Y, Lotze T, Mar S, Rensel M, Abrams A, Rodriguez M, Rose J, Schreiner T, Shukla N, Waubant E, Weinstock-Guttman B, Ness J, Krupp L, Mendelt-Tillema J, U.S. Network of Pediatric Multiple Sclerosis Centers. Silent findings: Examination of asymptomatic demyelination in a pediatric US cohort. Multiple sclerosis and related disorders 2023. PMID: 36871372


  32. Horton MK, Shim JE, Wallace A, Graves JS, Aaen G, Greenberg B, Mar S, Wheeler Y, Weinstock-Guttman B, Waldman A, Schreiner T, Rodriguez M, Tillema JM, Chitnis T, Krupp L, Casper TC, Rensel M, Hart J, Quach HL, Quach DL, Schaefer C, Waubant E, Barcellos LF. Rare and low-frequency coding genetic variants contribute to pediatric-onset multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2023. PMID: 36755464


  33. Nasr Z, Schoeps VA, Ziaei A, Virupakshaiah A, Adams C, Casper TC, Waltz M, Rose J, Rodriguez M, Tillema JM, Chitnis T, Graves JS, Benson L, Rensel M, Krupp L, Waldman AT, Weinstock-Guttman B, Lotze T, Greenberg B, Aaen G, Mar S, Schreiner T, Hart J, Simpson-Yap S, Mesaros C, Barcellos LF, Waubant E. Gene-environment interactions increase the risk of paediatric-onset multiple sclerosis associated with household chemical exposures. Journal of neurology, neurosurgery, and psychiatry 2023. PMID: 36725329


  34. Horton MK, Robinson SC, Shao X, Quach H, Quach D, Choudhary V, Bellesis KH, Dorin P, Mei J, Chinn T, Meyers TJ, Bakshi N, Marcus JF, Waubant E, Schaefer CA, Barcellos LF. A Cross-Trait, Mendelian Randomization Study to Investigate Whether Migraine Is a Risk Factor for Multiple Sclerosis. Neurology 2023. PMID: 36631270



  35. Umeton RP, Waltz M, Aaen GS, Benson L, Gorman M, Goyal M, Graves JS, Harris Y, Krupp L, Lotze TE, Shukla NM, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, Roalstad S, Rodriguez M, Rose J, Waubant E, Weinstock-Guttman B, Casper C, Chitnis T, and the U.S. Network of Pediatric MS Centers. Therapeutic Response in Pediatric Neuromyelitis Optica Spectrum Disorder. Neurology 2022. PMID: 36460473




  36. Gaudioso CM, Mar S, Casper TC, Codden R, Nguyen A, Aaen G, Benson L, Chitnis T, Francisco C, Gorman MP, Goyal MS, Graves J, Greenberg BM, Hart J, Krupp L, Lotze T, Narula S, Pittock SJ, Rensel M, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Wheeler Y, Waubant E, Flanagan EP, United States Network of Pediatric Multiple Sclerosis Centers. MOG and AQP4 Antibodies among Children with Multiple Sclerosis and Controls. Annals of neurology 2022. PMID: 36088544


  37. Krupp LB, Waubant E, Waltz M, Casper TC, Belman A, Wheeler Y, Ness J, Graves J, Gorman M, Benson L, Mar S, Goyal M, Schreiner T, Weinstock-Guttman B, Rodriguez M, Tillema JM, Lotze T, Aaen G, Rensel M, Rose J, Chitinis T, George A, Charvet LE, and the US Network of Pediatric MS Centers. A new look at cognitive functioning in pediatric MS. Multiple sclerosis (Houndmills, Basingstoke, England) 2022. PMID: 36189711



  38. Mirza AI, Zhu F, Knox N, Forbes JD, Bonner C, Van Domselaar G, Bernstein CN, Graham M, Marrie RA, Hart J, Yeh EA, Arnold DL, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H. The metabolic potential of the paediatric-onset multiple sclerosis gut microbiome. 2022. PMID: 35500534


  39. Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of CaliforniaSan Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG. Reply to "Spinal cord atrophy is a preclinical marker of progressive MS". 2022. PMID: 35233827


  40. Liang G, Zhu F, Mirza AI, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E, Tremlett H, Canadian Paediatric Demyelinating Disease Network. Stability of the gut microbiota in persons with paediatric-onset multiple sclerosis and related demyelinating diseases. 2022. PMID: 35296164


  41. Hardy D, Chitnis T, Waubant E, Banwell B. Preventing Multiple Sclerosis: The Pediatric Perspective. 2022. PMID: 35280298


  42. Krupp L, Banwell B, Chitnis T, Deiva K, Gaertner J, Ghezzi A, Huppke P, Waubant E, DeLasHeras V, Azmon A, Karan R. Effect of fingolimod on health-related quality of life in paediatric patients with multiple sclerosis: results from the phase 3 PARADIGMS Study. 2022. PMID: 35308898


  43. Ziaei A, Lavery AM, Shao XM, Adams C, Casper TC, Rose J, Candee M, Weinstock-Guttman B, Aaen G, Harris Y, Graves J, Benson L, Gorman M, Rensel M, Mar S, Lotze T, Greenberg B, Chitnis T, Hart J, Waldman AT, Barcellos LF, Waubant E. Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution. 2022. PMID: 35000467


  44. Bischof A, Papinutto N, Keshavan A, Rajesh A, Kirkish G, Zhang X, Mallott JM, Asteggiano C, Sacco S, Gundel TJ, Zhao C, Stern WA, Caverzasi E, Zhou Y, Gomez R, Ragan NR, Santaniello A, Zhu AH, Juwono J, Bevan CJ, Bove RM, Crabtree E, Gelfand JM, Goodin DS, Graves JS, Green AJ, Oksenberg JR, Waubant E, Wilson MR, Zamvil SS, University of California, San Francisco MS-EPIC Team, Cree BA, Hauser SL, Henry RG. Spinal cord atrophy predicts progressive disease in relapsing multiple sclerosis. 2021. PMID: 34878197


  45. Mirza AI, Zhu F, Knox N, Forbes JD, Van Domselaar G, Bernstein CN, Graham M, Marrie RA, Hart J, Yeh EA, Arnold D, Bar-Or A, O'Mahony J, Zhao Y, Hsiao W, Banwell B, Waubant E, Tremlett H. Metagenomic Analysis of the Pediatric-Onset Multiple Sclerosis Gut Microbiome. 2021. PMID: 34937787


  46. Tremlett H, Zhu F, Arnold D, Bar-Or A, Bernstein CN, Bonner C, Forbes JD, Graham M, Hart J, Knox NC, Marrie RA, Mirza AI, O'Mahony J, Van Domselaar G, Yeh EA, Zhao Y, Banwell B, Waubant E, US Network of Pediatric MS Centers, the Canadian Pediatric Demyelinating Disease Network. The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes. 2021. PMID: 34889081


  47. Sebastian P, Cherbuin N, Barcellos LF, Roalstad S, Casper C, Hart J, Aaen GS, Krupp L, Benson L, Gorman M, Candee M, Chitnis T, Goyal M, Greenberg B, Mar S, Rodriguez M, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Graves J, Waubant E, Lucas R, US Network of Pediatric Multiple Sclerosis Centers. Association Between Time Spent Outdoors and Risk of Multiple Sclerosis. 2021. PMID: 34880094


  48. Pilotto S, Gencarelli J, Bova S, Gerosa L, Baroncini D, Olivotto S, Alfei E, Zaffaroni M, Suppiej A, Cocco E, Trojano M, Amato MP, D'Alfonso S, Martinelli-Boneschi F, Waubant E, Ghezzi A, Bergamaschi R, Pugliatti M. Etiological research in pediatric multiple sclerosis: A tool to assess environmental exposures (PEDiatric Italian Genetic and enviRonment ExposurE Questionnaire). 2021. PMID: 34868629



  49. Sormani MP, Waubant E. Paediatric multiple sclerosis: a lesson from TERIKIDS. 2021. PMID: 34800403


  50. Fitzgerald KC, Smith MD, Kim S, Sotirchos ES, Kornberg MD, Douglas M, Nourbakhsh B, Graves J, Rattan R, Poisson L, Cerghet M, Mowry EM, Waubant E, Giri S, Calabresi PA, Bhargava P. Multi-omic evaluation of metabolic alterations in multiple sclerosis identifies shifts in aromatic amino acid metabolism. 2021. PMID: 34755135


  51. Mandel LA, O'Donnell E, Canenguez K, Castro-Mendoza PB, Lotze T, Waubant E, Weinstock-Guttmann B, Chitnis T. Family Perspectives on Clinical Research for Pediatric Multiple Sclerosis: Enhancing Equity. Journal of Patient Experience 2021. PMID: 34541304


  52. Lui A, Chong J, Flanagan E, Abrams AW, Krysko KM, Arikan B, Francisco C, Rutatangwa A, Waubant E, Ziaei A. High titers of myelin oligodendrocyte glycoprotein antibody are only observed close to clinical events in pediatrics. Multiple sclerosis and related disorders 2021. PMID: 34517190


  53. Santoro JD, Kerr LM, Codden R, Casper TC, Greenberg BM, Waubant E, Kong SW, Mandl KD, Gorman MP. Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome. Neurology(R) neuroimmunology & neuroinflammation 2021. PMID: 34475249


  54. Marignier R, Hacohen Y, Cobo-Calvo A, Pröbstel AK, Aktas O, Alexopoulos H, Amato MP, Asgari N, Banwell B, Bennett J, Brilot F, Capobianco M, Chitnis T, Ciccarelli O, Deiva K, De Sèze J, Fujihara K, Jacob A, Kim HJ, Kleiter I, Lassmann H, Leite MI, Linington C, Meinl E, Palace J, Paul F, Petzold A, Pittock S, Reindl M, Sato DK, Selmaj K, Siva A, Stankoff B, Tintore M, Traboulsee A, Waters P, Waubant E, Weinshenker B, Derfuss T, Vukusic S, Hemmer B. Myelin-oligodendrocyte glycoprotein antibody-associated disease. The Lancet. Neurology 2021. PMID: 34418402


  55. Horton MK, McCauley K, Fadrosh D, Fujimura K, Graves J, Ness J, Wheeler Y, Gorman MP, Benson LA, Weinstock-Guttman B, Waldman A, Rodriguez M, Tillema JM, Krupp L, Belman A, Mar S, Rensel M, Chitnis T, Casper TC, Rose J, Hart J, Shao X, Tremlett H, Lynch SV, Barcellos LF, Waubant E, U.S. Network of Pediatric MS Centers. Gut microbiome is associated with multiple sclerosis activity in children. Annals of clinical and translational neurology 2021. PMID: 34409759


  56. Greenberg BM, Casper TC, Mar SS, Ness JM, Plumb P, Liang S, Goyal M, Weinstock-Guttman B, Rodriguez M, Aaen GS, Belman A, Barcellos LF, Rose JW, Gorman MP, Benson LA, Candee M, Chitnis T, Harris YC, Kahn IL, Roalstad S, Hart J, Lotze TE, Rensel M, Rubin JP, Schreiner TL, Tillema JM, Waldman AT, Krupp L, Graves J, Drake K, Waubant E. Familial History of Autoimmune Disorders Among Patients With Pediatric Multiple Sclerosis. Neurology(R) neuroimmunology & neuroinflammation 2021. PMID: 34353894




  57. Nourbakhsh B, Cordano C, Asteggiano C, Ruprecht K, Otto C, Rutatangwa A, Lui A, Hart J, Flanagan EP, James JA, Waubant E. Multiple Sclerosis Is Rare in Epstein-Barr Virus-Seronegative Children with Central Nervous System Inflammatory Demyelination. Annals of neurology 2021. PMID: 33704815


  58. Krysko KM, Bischof A, Nourbakhsh B, Henry RG, Revirajan N, Manguinao M, Nguyen K, Akula A, Li Y, Waubant E. A pilot study of oxidative pathways in MS fatigue: randomized trial of N-acetyl cysteine. Annals of clinical and translational neurology 2021. PMID: 33675156


  59. Bermel RA, Waubant E, Pardo G, Bass A, Repovic P, Newsome S, Lindsey JW, Kile D, Pradhan A, Musch B, Zabeti A. Safety evaluation of shorter infusion for ocrelizumab in a substudy of the Phase IIIb CHORDS trial. Annals of clinical and translational neurology 2021. PMID: 33621404


  60. Nourbakhsh B, Revirajan N, Morris B, Cordano C, Creasman J, Manguinao M, Krysko K, Rutatangwa A, Auvray C, Aljarallah S, Jin C, Mowry E, McCulloch C, Waubant E. Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial. The Lancet. Neurology 2020. PMID: 33242419


  61. Krysko KM, Akhbardeh A, Arjona J, Nourbakhsh B, Waubant E, Antoine Gourraud P, Graves JS. Biosensor vital sign detects multiple sclerosis progression. Annals of clinical and translational neurology 2020. PMID: 33211403


  62. Sacco S, Caverzasi E, Papinutto N, Cordano C, Bischof A, Gundel T, Cheng S, Asteggiano C, Kirkish G, Mallott J, Stern WA, Bastianello S, Bove RM, Gelfand JM, Goodin DS, Green AJ, Waubant E, Wilson MR, Zamvil SS, Cree BA, Hauser SL, Henry RG, University of California, San Francisco MS-EPIC Team. Neurite Orientation Dispersion and Density Imaging for Assessing Acute Inflammation and Lesion Evolution in MS. AJNR. American journal of neuroradiology 2020. PMID: 33154077


  63. Chitnis T, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Ness J, Rensel M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Roalstad S, Rose J, Weiner HL, Casper TC, Rodriguez M, US Network of Paediatric Multiple Sclerosis Centers. Improved relapse recovery in paediatric compared to adult multiple sclerosis. Brain : a journal of neurology 2020. PMID: 32810215


  64. Santoro JD, Waltz M, Aaen G, Belman A, Benson L, Gorman M, Goyal MS, Graves JS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rensel M, Rodriguez M, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Hurtubise BF, Roalstad S, Rose J, Casper TC, Chitnis T, US Network of Pediatric MS Centers. Pediatric Multiple Sclerosis Severity Score in a large US cohort. Neurology 2020. PMID: 32690790


  65. Barcellos LF, Horton M, Shao X, Bellesis KH, Chinn T, Waubant E, Bakshi N, Marcus J, Benedict RH, Schaefer C. A validation study for remote testing of cognitive function in multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2020. PMID: 32662747




  66. Chitnis T, Banwell B, Krupp L, Arnold DL, Bar-Or A, Brück W, Giovannoni G, Greenberg B, Ghezzi A, Waubant E, Rostasy K, Deiva K, Huppke P, Wolinsky JS, Zhang Y, Azmon A, K-Laflamme A, Karan R, Gärtner J. Temporal profile of lymphocyte counts and relationship with infections with fingolimod therapy in paediatric patients with multiple sclerosis: Results from the PARADIGMS study. Multiple sclerosis (Houndmills, Basingstoke, England) 2020. PMID: 32633694


  67. Bhargava P, Smith MD, Mische L, Harrington E, Fitzgerald KC, Martin K, Kim S, Reyes AA, Gonzalez-Cardona J, Volsko C, Tripathi A, Singh S, Varanasi K, Lord HN, Meyers K, Taylor M, Gharagozloo M, Sotirchos ES, Nourbakhsh B, Dutta R, Mowry EM, Waubant E, Calabresi PA. Bile acid metabolism is altered in multiple sclerosis and supplementation ameliorates neuroinflammation. The Journal of clinical investigation 2020. PMID: 32182223


  68. Giovannoni G, Hawkes CH, Lechner-Scott J, Levy M, Waubant E. Dare we mention the C-word? Multiple sclerosis and related disorders 2020. PMID: 32660744


  69. Ghezzi A, Banwell B, Bar-Or A, Chitnis T, Dale RC, Gorman M, Kornek B, Krupp L, Krysko KM, Nosadini M, Rostasy K, Salzer J, Schreiner T, Tenembaum S, Waubant E. Rituximab in patients with pediatric multiple sclerosis and other demyelinating disorders of the CNS: Practical considerations. Multiple sclerosis (Houndmills, Basingstoke, England) 2020. PMID: 32552353


  70. Maghzi AH, Sicotte NL, Waubant E. Do you believe in Gad? Multiple sclerosis and related disorders 2020. PMID: 32593143



  71. Rutatangwa A, Mittal N, Francisco C, Nash K, Waubant E. Autoimmune Encephalitis in Children: A Case Series at a Tertiary Care Center. Journal of child neurology 2020. PMID: 32458722


  72. Krysko KM, Graves JS, Rensel M, Weinstock-Guttman B, Rutatangwa A, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Goyal MS, Harris Y, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waltz M, Casper TC, Waubant E, US Network of Pediatric MS Centers. Real-World Effectiveness of Initial Disease-Modifying Therapies in Pediatric Multiple Sclerosis. Annals of neurology 2020. PMID: 32267005


  73. Lechner-Scott J, Waubant E, Levy M, Hawkes C, Giovannoni G. Is multiple sclerosis a risk factor for infections? Multiple sclerosis and related disorders 2020. PMID: 32571610


  74. Waubant E, Pröbstel AK, Levy M, Hawkes CH, Giovannoni G, Lechner-Scott J, Tremlett H. The future of microbiome research in neuroinflammatory disorders. Multiple sclerosis and related disorders 2020. PMID: 32312515


  75. Hawkes CH, Giovannoni G, Levy M, Lechner-Scott J, Waubant E. Big pharma and social responsibility. Multiple sclerosis and related disorders 2020. PMID: 32334821


  76. Giovannoni G, Hawkes C, Lechner-Scott J, Levy M, Waubant E, Gold J. The COVID-19 pandemic and the use of MS disease-modifying therapies. Multiple sclerosis and related disorders 2020. PMID: 32334820


  77. Arnold DL, Banwell B, Bar-Or A, Ghezzi A, Greenberg BM, Waubant E, Giovannoni G, Wolinsky JS, Gärtner J, Rostásy K, Krupp L, Tardieu M, Brück W, Stites TE, Pearce GL, Häring DA, Merschhemke M, Chitnis T, PARADIGMS Study Investigators. Effect of fingolimod on MRI outcomes in patients with paediatric-onset multiple sclerosis: results from the phase 3 PARADIGMS study. Journal of neurology, neurosurgery, and psychiatry 2020. PMID: 32132224



  78. Giovannoni G, Hawkes CH, Lechner-Scott J, Levy M, Waubant E. Ageing and multiple sclerosis. Multiple sclerosis and related disorders 2020. PMID: 32164909


  79. Levy M, Waubant E, Hawkes C, Giovannoni G, Lechner-Scott J. "Is this new medicine going to help me walk again?" Multiple sclerosis and related disorders 2019. PMID: 32172990


  80. Wallach AI, Waltz M, Casper TC, Aaen G, Belman A, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze TE, Mar S, Moodley M, Ness JM, Rensel M, Rodriguez M, Rose JW, Schreiner T, Tillema JM, Waubant E, Weinstock-Guttman B, Charvet LE, Krupp LB. Cognitive processing speed in pediatric-onset multiple sclerosis: Baseline characteristics of impairment and prediction of decline. Multiple sclerosis (Houndmills, Basingstoke, England) 2019. PMID: 31775571


  81. Lechner-Scott J, Waubant E, Levy M, Hawkes C. Silent symptoms of multiple sclerosis. Multiple sclerosis and related disorders 2019. PMID: 31812240



  82. Mirza A, Forbes JD, Zhu F, Bernstein CN, Van Domselaar G, Graham M, Waubant E, Tremlett H. The multiple sclerosis gut microbiota: A systematic review. Multiple sclerosis and related disorders 2019. PMID: 32172998


  83. Jonzzon S, Suleiman L, Yousef A, Young B, Hart J, Peschl P, Reindl M, Schaller KL, Bennett JL, Waubant E, Graves JS. Clinical Features and Outcomes of Pediatric Monophasic and Recurrent Idiopathic Optic Neuritis. Journal of child neurology 2019. PMID: 31566057


  84. Langer-Gould A, Black LJ, Waubant E, Smith JB, Wu J, Gonzales EG, Shao X, Koebnick C, Lucas RM, Xiang A, Barcellos LF. Seafood, fatty acid biosynthesis genes, and multiple sclerosis susceptibility. Multiple sclerosis (Houndmills, Basingstoke, England) 2019. PMID: 33063621


  85. Deiva K, Huppke P, Banwell B, Chitnis T, Gärtner J, Krupp L, Waubant E, Stites T, Pearce GL, Merschhemke M. Consistent control of disease activity with fingolimod versus IFN ß-1a in paediatric-onset multiple sclerosis: further insights from PARADIGMS. Journal of neurology, neurosurgery, and psychiatry 2019. PMID: 31467033


  86. Waubant E, Lucas R, Mowry E, Graves J, Olsson T, Alfredsson L, Langer-Gould A. Environmental and genetic risk factors for MS: an integrated review. Annals of clinical and translational neurology 2019. PMID: 31392849



  87. Hawkes CH, Giovannoni G, Lechner-Scott J, Levy M, Waubant E. Multiple sclerosis and migration revisited. Multiple sclerosis and related disorders 2019. PMID: 31543261


  88. Manguinao M, Krysko KM, Maddike S, Rutatangwa A, Francisco C, Hart J, Chong J, Graves JS, Waubant E. A retrospective cohort study of plasma exchange in central nervous system demyelinating events in children. Multiple sclerosis and related disorders 2019. PMID: 31319355


  89. Pardo S, Giovannoni G, Hawkes C, Lechner-Scott J, Waubant E, Levy M. Editorial on: Eculizumab in aquaporin-4-positive neuromyelitis optica spectrum disorder. Multiple sclerosis and related disorders 2019. PMID: 31324299


  90. Jokubaitis VG, Pröbstel AK, Arrambide G, Costello F, Waubant E. Introducing the International Women in Multiple Sclerosis network. The Lancet. Neurology 2019. PMID: 31122489


  91. Rhead B, Shao X, Graves JS, Chitnis T, Waldman AT, Lotze T, Schreiner T, Belman A, Krupp L, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee MS, Gorman M, Benson L, Mar S, Kahn I, Rose J, Casper TC, Quach H, Quach D, Schaefer C, Waubant E, Barcellos LF, US Network of Pediatric MS Centers. miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS. Annals of clinical and translational neurology 2019. PMID: 31211169


  92. Graves JS, Barcellos LF, Krupp L, Belman A, Shao X, Quach H, Hart J, Chitnis T, Weinstock-Guttman B, Aaen G, Benson L, Gorman M, Greenberg B, Lotze T, Soe M, Ness J, Rodriguez M, Rose J, Schreiner T, Tillema JM, Waldman A, Casper TC, Waubant E. Vitamin D genes influence MS relapses in children. Multiple sclerosis (Houndmills, Basingstoke, England) 2019. PMID: 31081484


  93. Waubant E, Banwell B, Wassmer E, Sormani MP, Amato MP, Hintzen R, Krupp L, Rostásy K, Tenembaum S, Chitnis T, IPMSSG. Clinical trials of disease-modifying agents in pediatric MS: Opportunities, challenges, and recommendations from the IPMSSG. Neurology 2019. PMID: 31043474


  94. Waubant E, Giovannoni G, Hawkes C, Lechner-Scott J, Levy M. Three suggestions to decrease the financial burden of MS treatments. Multiple sclerosis and related disorders 2019. PMID: 30987755


  95. Lechner-Scott J, Giovannoni G, Hawkes C, Levy M, Waubant E. One size doesn't fit all. Multiple sclerosis and related disorders 2019. PMID: 31159999




  96. Hawkes C, Giovannoni G, Lechner-Scott J, Levy M, Waubant E. Multiple Sclerosis and Vitamin D - Caviar or a Dog's Dinner? Multiple sclerosis and related disorders 2019. PMID: 30823982


  97. Chi C, Shao X, Rhead B, Gonzales E, Smith JB, Xiang AH, Graves J, Waldman A, Lotze T, Schreiner T, Weinstock-Guttman B, Aaen G, Tillema JM, Ness J, Candee M, Krupp L, Gorman M, Benson L, Chitnis T, Mar S, Belman A, Casper TC, Rose J, Moodley M, Rensel M, Rodriguez M, Greenberg B, Kahn L, Rubin J, Schaefer C, Waubant E, Langer-Gould A, Barcellos LF. Admixture mapping reveals evidence of differential multiple sclerosis risk by genetic ancestry. PLoS genetics 2019. PMID: 30653506


  98. Giovannoni G, Hawkes C, Levy M, Lechner-Scott J, Waubant E. Should our treatment target in MS include the intrathecal plasma cell response? Multiple sclerosis and related disorders 2019. PMID: 30642567


  99. Aaen G, Waltz M, Vargas W, Makhani N, Ness J, Harris Y, Casper TC, Benson L, Candee M, Chitnis T, Gorman M, Graves J, Greenberg B, Lotze T, Mar S, Tillema JM, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Waldman A, Weinstock-Guttman B, Belman A, Waubant E, Krupp L. Acquisition of Early Developmental Milestones and Need for Special Education Services in Pediatric Multiple Sclerosis. Journal of child neurology 2018. PMID: 30556452



  100. Yousef A, Devereux M, Gourraud PA, Jonzzon S, Suleiman L, Waubant E, Green A, Graves JS. Subclinical Saccadic Eye Movement Dysfunction in Pediatric Multiple Sclerosis. Journal of child neurology 2018. PMID: 30463467


  101. Mowry EM, Azevedo CJ, McCulloch CE, Okuda DT, Lincoln RR, Waubant E, Hauser SL, Pelletier D. Body mass index, but not vitamin D status, is associated with brain volume change in MS. Neurology 2018. PMID: 30429274


  102. Waubant E, Giovannoni G, Hawkes C, Levy M. Vaccines and disease-modifying treatments. Multiple sclerosis and related disorders 2018. PMID: 30573174



  103. Krysko KM, Graves J, Rensel M, Weinstock-Guttman B, Aaen G, Benson L, Chitnis T, Gorman M, Goyal M, Krupp L, Lotze T, Mar S, Rodriguez M, Rose J, Waltz M, Charles Casper T, Waubant E, US Network of Pediatric MS Centers. Use of newer disease-modifying therapies in pediatric multiple sclerosis in the US. Neurology 2018. PMID: 30333163


  104. Mar S, Liang S, Waltz M, Casper TC, Goyal M, Greenberg B, Weinstock-Guttman B, Rodriguez M, Aaen G, Belman A, Barcellos LF, Rose J, Gorman M, Benson L, Candee M, Chitnis T, Harris Y, Kahn I, Roalsted S, Hart J, Lotze T, Moodley M, Ness J, Rensel M, Rubin J, Schreiner T, Tillema JM, Waldman A, Krupp L, Graves JS, Waubant E, U.S. Network of Pediatric Multiple Sclerosis Centers. Several household chemical exposures are associated with pediatric-onset multiple sclerosis. Annals of clinical and translational neurology 2018. PMID: 30564618


  105. Bartolini L, Piras E, Sullivan K, Gillen S, Bumbut A, Lin CM, Leibovitch EC, Graves JS, Waubant EL, Chamberlain JM, Gaillard WD, Jacobson S. Detection of HHV-6 and EBV and Cytokine Levels in Saliva From Children With Seizures: Results of a Multi-Center Cross-Sectional Study. Frontiers in neurology 2018. PMID: 30344507




  106. Lavery AM, Waubant E, Casper TC, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Charvet L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waldman AT. Urban air quality and associations with pediatric multiple sclerosis. Annals of clinical and translational neurology 2018. PMID: 30349849


  107. Nourbakhsh B, Rutatangwa A, Waltz M, Rensel M, Moodley M, Graves J, Casper TC, Waldman A, Belman A, Greenberg B, Goyal M, Harris Y, Kahn I, Lotze T, Mar S, Schreiner T, Aaen G, Hart J, Ness J, Rubin J, Tillema JM, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Candee M, Weinstock-Guttman B, Shao X, Barcellos L, James J, Waubant E, US Network of Pediatric MS Centers. Heterogeneity in association of remote herpesvirus infections and pediatric MS. Annals of clinical and translational neurology 2018. PMID: 30349857


  108. Chitnis T, Arnold DL, Banwell B, Brück W, Ghezzi A, Giovannoni G, Greenberg B, Krupp L, Rostásy K, Tardieu M, Waubant E, Wolinsky JS, Bar-Or A, Stites T, Chen Y, Putzki N, Merschhemke M, Gärtner J, PARADIGMS Study Group. Trial of Fingolimod versus Interferon Beta-1a in Pediatric Multiple Sclerosis. The New England journal of medicine 2018. PMID: 30207920


  109. Hawkes CH, Giovannoni G, Levy M, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2018. PMID: 30190056


  110. Giovannoni G, Hawkes C, Levy M, Waubant E. Is cognitive impairment in multiple sclerosis reversible? Multiple sclerosis and related disorders 2018. PMID: 30049507


  111. Waubant E, Berkowitz A, Giovannoni G, Hawkes C, Levy M. Diagnosing and caring for MS in Haiti. Multiple sclerosis and related disorders 2018. PMID: 29807822


  112. Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE, Pediatric MS Adherence Study Group. Correction to: Impact of an electronic monitoring device and behavioural feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2018. PMID: 29274015



  113. Suleiman L, Waubant E, Aaen G, Belman A, Benson L, Candee M, Chitnis T, Gorman M, Goyal M, Greenberg B, Harris Y, Hart J, Kahn I, Krupp L, Lotze T, Mar S, Moodley M, Ness J, Nourbakhsh B, Rensel M, Rodriguez M, Rose J, Rubin J, Schreiner T, Tillema JM, Waldman A, Weinstock-Guttman B, Casper TC, Waltz M, Graves JS, Network of Pediatric Multiple Sclerosis Centers.. Early infectious exposures are not associated with increased risk of pediatric-onset multiple sclerosis. Multiple sclerosis and related disorders 2018. PMID: 29653437





  114. Hawkes C, Giovannoni G, Levy M, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2018. PMID: 29579630


  115. Giovannoni G, Hawkes C, Levy M, Lublin F, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2018. PMID: 29409600





  116. Graves JS, Henry RG, Cree BAC, Lambert-Messerlian G, Greenblatt RM, Waubant E, Cedars MI, Zhu A, University of California, San Francisco MS-EPIC Team, , Bacchetti P, Hauser SL, Oksenberg JR. Ovarian aging is associated with gray matter volume and disability in women with MS. Neurology 2017. PMID: 29273686


  117. Thompson AJ, Banwell BL, Barkhof F, Carroll WM, Coetzee T, Comi G, Correale J, Fazekas F, Filippi M, Freedman MS, Fujihara K, Galetta SL, Hartung HP, Kappos L, Lublin FD, Marrie RA, Miller AE, Miller DH, Montalban X, Mowry EM, Sorensen PS, Tintoré M, Traboulsee AL, Trojano M, Uitdehaag BMJ, Vukusic S, Waubant E, Weinshenker BG, Reingold SC, Cohen JA. Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria. The Lancet. Neurology 2017. PMID: 29275977



  118. Waubant E, Giovannoni G, Hawkes C, Lublin F. Editors' Welcome. Multiple sclerosis and related disorders 2017. PMID: 29141832


  119. Graves JS, Barcellos LF, Simpson S, Belman A, Lin R, Taylor BV, Ponsonby AL, Dwyer T, Krupp L, Waubant E, van der Mei IAF. The multiple sclerosis risk allele within the AHI1 gene is associated with relapses in children and adults. Multiple sclerosis and related disorders 2017. PMID: 29409597


  120. Azary S, Schreiner T, Graves J, Waldman A, Belman A, Guttman BW, Aaen G, Tillema JM, Mar S, Hart J, Ness J, Harris Y, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos LF, Lotze T, Carmichael SL, Roalstad S, Casper CT, Waubant E. Contribution of dietary intake to relapse rate in early paediatric multiple sclerosis. Journal of neurology, neurosurgery, and psychiatry 2017. PMID: 28993476


  121. Gianfrancesco MA, Stridh P, Shao X, Rhead B, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Schaefer C, Barcellos LF, Waubant E, Network of Pediatric Multiple Sclerosis Centers. Genetic risk factors for pediatric-onset multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2017. PMID: 28980494


  122. Lublin F, Giovannoni G, Hawkes C, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2017. PMID: 29055486



  123. Lavery AM, Waldman AT, Charles Casper T, Roalstad S, Candee M, Rose J, Belman A, Weinstock-Guttman B, Aaen G, Tillema JM, Rodriguez M, Ness J, Harris Y, Graves J, Krupp L, Benson L, Gorman M, Moodley M, Rensel M, Goyal M, Mar S, Chitnis T, Schreiner T, Lotze T, Greenberg B, Kahn I, Rubin J, Waubant E, U.S. Network of Pediatric MS Centers. Examining the contributions of environmental quality to pediatric multiple sclerosis. Multiple sclerosis and related disorders 2017. PMID: 29141802


  124. Hawkes C, Giovannoni G, Lublin F, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2017. PMID: 28755685


  125. Zhou Y, Graves JS, Simpson S, Charlesworth JC, Mei IV, Waubant E, Barcellos LF, Belman A, Krupp L, Lucas R, Ponsonby AL, Taylor BV, Ausimmmune/AusLong investigators group. Genetic variation in the gene LRP2 increases relapse risk in multiple sclerosis. Journal of neurology, neurosurgery, and psychiatry 2017. PMID: 28739605


  126. Pakpoor J, Goldacre R, Schmierer K, Giovannoni G, Waubant E, Goldacre MJ. Psychiatric disorders in children with demyelinating diseases of the central nervous system. Multiple sclerosis (Houndmills, Basingstoke, England) 2017. PMID: 28675955



  127. Pakpoor J, Seminatore B, Graves JS, Schreiner T, Waldman AT, Lotze TE, Belman A, Greenberg BM, Weinstock-Guttman B, Aaen G, Tillema JM, McDonald JC, Hart J, Ness JM, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Kahn I, Rose J, Carmichael SL, Roalstad S, Waltz M, Casper TC, Waubant E, US Network of Pediatric Multiple Sclerosis Centers. Dietary factors and pediatric multiple sclerosis: A case-control study. Multiple sclerosis (Houndmills, Basingstoke, England) 2017. PMID: 28608728


  128. Quintanilla-Bordás C, Nourbakhsh B, Strober J, Raffel C, Waubant E. Clinical Reasoning: A 16-year-old girl with subacute weakness and sensory loss. Neurology 2017. PMID: 28583938


  129. Waubant E, Giovannoni G, Hawkes C, Lublin F. Editors' welcome. Multiple sclerosis and related disorders 2017. PMID: 28619438


  130. Yeh EA, Grover SA, Powell VE, Alper G, Banwell BL, Edwards K, Gorman M, Graves J, Lotze TE, Mah JK, Mednick L, Ness J, Obadia M, Slater R, Waldman A, Waubant E, Schwartz CE, Pediatric MS Adherence Study Group. Impact of an electronic monitoring device and behavioral feedback on adherence to multiple sclerosis therapies in youth: results of a randomized trial. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2017. PMID: 28393317


  131. Lublin F, Giovannoni G, Hawkes C, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2017. PMID: 28427712


  132. Graves JS, Chitnis T, Weinstock-Guttman B, Rubin J, Zelikovitch AS, Nourbakhsh B, Simmons T, Waltz M, Casper TC, Waubant E, Network of Pediatric Multiple Sclerosis Centers. Maternal and Perinatal Exposures Are Associated With Risk for Pediatric-Onset Multiple Sclerosis. Pediatrics 2017. PMID: 28562303


  133. Gianfrancesco MA, Stridh P, Rhead B, Shao X, Xu E, Graves JS, Chitnis T, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Caillier S, Ness J, Harris Y, Rubin J, Candee M, Krupp L, Gorman M, Benson L, Rodriguez M, Mar S, Kahn I, Rose J, Roalstad S, Casper TC, Shen L, Quach H, Quach D, Hillert J, Bäärnhielm M, Hedstrom A, Olsson T, Kockum I, Alfredsson L, Metayer C, Schaefer C, Barcellos LF, Waubant E, Network of Pediatric Multiple Sclerosis Centers. Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS. Neurology 2017. PMID: 28356466


  134. Tremlett H, Bauer KC, Appel-Cresswell S, Finlay BB, Waubant E. The gut microbiome in human neurological disease: A review. Annals of neurology 2017. PMID: 28220542


  135. Hawkes C, Giovannoni G, Lublin F, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2017. PMID: 28283115


  136. Schwartz CE, Grover SA, Powell VE, Noguera A, Mah JK, Mar S, Mednick L, Banwell BL, Alper G, Rensel M, Gorman M, Waldman A, Schreiner T, Waubant E, Yeh EA. Risk factors for non-adherence to disease-modifying therapy in pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2017. PMID: 28273780


  137. Kuhle J, Nourbakhsh B, Grant D, Morant S, Barro C, Yaldizli Ö, Pelletier D, Giovannoni G, Waubant E, Gnanapavan S. Serum neurofilament is associated with progression of brain atrophy and disability in early MS. Neurology 2017. PMID: 28148632


  138. Tremlett H, Waubant E. The multiple sclerosis microbiome? Annals of translational medicine 2017. PMID: 28251132


  139. Giovannoni G, Hawkes C, Lublin F, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2017. PMID: 28104262


  140. Chitnis T, Graves J, Weinstock-Guttman B, Belman A, Olsen C, Misra M, Aaen G, Benson L, Candee M, Gorman M, Greenberg B, Krupp L, Lotze T, Mar S, Ness J, Rose J, Rubin J, Schreiner T, Tillema J, Waldman A, Rodriguez M, Casper C, Waubant E, U.S. Network of Pediatric MS Centers. Distinct effects of obesity and puberty on risk and age at onset of pediatric MS. Annals of clinical and translational neurology 2016. PMID: 28097202


  141. Hawkes C, Lublin F, Giovannoni G, Waubant E. Editors' Welcome. Multiple sclerosis and related disorders 2016. PMID: 27919509


  142. Hatcher SE, Waubant E, Graves JS. Rebound Syndrome in Multiple Sclerosis After Fingolimod Cessation-Reply. JAMA neurology 2016. PMID: 27669526


  143. Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Spencer CM, Lynch SV, Zamvil SS, Waubant E, US Network of Pediatric MS Centers. Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls. BMC neurology 2016. PMID: 27652609


  144. Waubant E, Ponsonby AL, Pugliatti M, Hanwell H, Mowry EM, Hintzen RQ. Environmental and genetic factors in pediatric inflammatory demyelinating diseases. Neurology 2016. PMID: 27572857


  145. Wassmer E, Chitnis T, Pohl D, Amato MP, Banwell B, Ghezzi A, Hintzen RQ, Krupp LB, Makhani N, Rostásy K, Tardieu M, Tenembaum S, Waldman A, Waubant E, Kornberg AJ. International Pediatric MS Study Group Global Members Symposium report. Neurology 2016. PMID: 27572855


  146. Hanumanthe SB, Francisco C, Hart J, Graves J, Waubant E. Biopsy-Supported Tumefactive Demyelination of the Central Nervous System in Children. Journal of child neurology 2016. PMID: 27572815




  147. Graves JS, Chohan H, Cedars B, Arnow S, Yiu H, Waubant E, Green A. Sex differences and subclinical retinal injury in pediatric-onset MS. Multiple sclerosis (Houndmills, Basingstoke, England) 2016. PMID: 27306618


  148. Belman AL, Krupp LB, Olsen CS, Rose JW, Aaen G, Benson L, Chitnis T, Gorman M, Graves J, Harris Y, Lotze T, Ness J, Rodriguez M, Tillema JM, Waubant E, Weinstock-Guttman B, Casper TC, US Network of Pediatric MS Centers. Characteristics of Children and Adolescents With Multiple Sclerosis. Pediatrics 2016. PMID: 27358474


  149. Hatcher SE, Waubant E, Nourbakhsh B, Crabtree-Hartman E, Graves JS. Rebound Syndrome in Patients With Multiple Sclerosis After Cessation of Fingolimod Treatment. JAMA neurology 2016. PMID: 27135594


  150. Nourbakhsh B, Graves J, Casper TC, Lulu S, Waldman A, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Ness J, Rubin J, Krupp L, Gorman M, Benson L, Rodriguez M, Chitnis T, Rose J, Barcellos L, Waubant E, Network of Pediatric Multiple Sclerosis Centers. Dietary salt intake and time to relapse in paediatric multiple sclerosis. Journal of neurology, neurosurgery, and psychiatry 2016. PMID: 27343226


  151. Tremlett H, Fadrosh DW, Faruqi AA, Zhu F, Hart J, Roalstad S, Graves J, Lynch S, Waubant E, US Network of Pediatric MS Centers. Gut microbiota in early pediatric multiple sclerosis: a case-control study. European journal of neurology 2016. PMID: 27176462


  152. Nourbakhsh B, Azevedo C, Maghzi AH, Spain R, Pelletier D, Waubant E. Subcortical grey matter volumes predict subsequent walking function in early multiple sclerosis. Journal of the neurological sciences 2016. PMID: 27288812



  153. Tremlett H, Fadrosh DW, Faruqi AA, Hart J, Roalstad S, Graves J, Lynch S, Waubant E, US Network of Pediatric MS Centers. Gut microbiota composition and relapse risk in pediatric MS: A pilot study. Journal of the neurological sciences 2016. PMID: 27000242


  154. Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Reingold S, Cohen JA, attendees of the International Workshop on Comorbidity in Multiple Sclerosis. The challenge of comorbidity in clinical trials for multiple sclerosis. Neurology 2016. PMID: 26888986


  155. McDonald J, Graves J, Waldman A, Lotze T, Schreiner T, Belman A, Greenberg B, Weinstock-Guttman B, Aaen G, Tillema JM, Hart J, Lulu S, Ness J, Harris Y, Rubin J, Candee M, Krupp LB, Gorman M, Benson L, Rodriguez M, Chitnis T, Mar S, Barcellos LF, Laraia B, Rose J, Roalstad S, Simmons T, Casper TC, Waubant E. A case-control study of dietary salt intake in pediatric-onset multiple sclerosis. Multiple sclerosis and related disorders 2016. PMID: 27063630


  156. Marrie RA, Miller A, Sormani MP, Thompson A, Waubant E, Trojano M, O'Connor P, Fiest K, Reider N, Reingold S, Cohen JA, attendees of the International Workshop on Comorbidity in Multiple Sclerosis. Recommendations for observational studies of comorbidity in multiple sclerosis. Neurology 2016. PMID: 26865523


  157. Graves JS, Barcellos LF, Shao X, Noble J, Mowry EM, Quach H, Belman A, Casper TC, Krupp LB, Waubant E, U.S. Network of Pediatric MS Centers. Genetic predictors of relapse rate in pediatric MS. Multiple sclerosis (Houndmills, Basingstoke, England) 2016. PMID: 26769066


  158. Chitnis T, Ness J, Krupp L, Waubant E, Hunt T, Olsen CS, Rodriguez M, Lotze T, Gorman M, Benson L, Belman A, Weinstock-Guttman B, Aaen G, Graves J, Patterson M, Rose JW, Casper TC. Clinical features of neuromyelitis optica in children: US Network of Pediatric MS Centers report. Neurology 2015. PMID: 26683648


  159. Van Haren K, Ayscue P, Waubant E, Clayton A, Sheriff H, Yagi S, Glenn-Finer R, Padilla T, Strober JB, Aldrovandi G, Wadford DA, Chiu CY, Xia D, Harriman K, Watt JP, Glaser CA. Acute Flaccid Myelitis of Unknown Etiology in California, 2012-2015. JAMA 2015. PMID: 26720027



  160. Nourbakhsh B, Nunan-Saah J, Maghzi AH, Julian LJ, Spain R, Jin C, Lazar A, Pelletier D, Waubant E. Longitudinal associations between MRI and cognitive changes in very early MS. Multiple sclerosis and related disorders 2015. PMID: 26856943


  161. Nourbakhsh B, Azevedo C, Nunan-Saah J, Maghzi AH, Spain R, Pelletier D, Waubant E. Longitudinal associations between brain structural changes and fatigue in early MS. Multiple sclerosis and related disorders 2015. PMID: 26856940


  162. Goodin DS, Reder AT, Bermel RA, Cutter GR, Fox RJ, John GR, Lublin FD, Lucchinetti CF, Miller AE, Pelletier D, Racke MK, Trapp BD, Vartanian T, Waubant E. Relapses in multiple sclerosis: Relationship to disability. Multiple sclerosis and related disorders 2015. PMID: 27063617


  163. Bhargava P, Steele SU, Waubant E, Revirajan NR, Marcus J, Dembele M, Cassard SD, Hollis BW, Crainiceanu C, Mowry EM. Multiple sclerosis patients have a diminished serologic response to vitamin D supplementation compared to healthy controls. Multiple sclerosis (Houndmills, Basingstoke, England) 2015. PMID: 26286698


  164. Schlaeger R, Papinutto N, Zhu AH, Lobach IV, Bevan CJ, Bucci M, Castellano A, Gelfand JM, Graves JS, Green AJ, Jordan KM, Keshavan A, Panara V, Stern WA, von Büdingen HC, Waubant E, Goodin DS, Cree BA, Hauser SL, Henry RG. Association Between Thoracic Spinal Cord Gray Matter Atrophy and Disability in Multiple Sclerosis. JAMA neurology 2015. PMID: 26053119


  165. Melamed E, Levy M, Waters PJ, Sato DK, Bennett JL, John GR, Hooper DC, Saiz A, Bar-Or A, Kim HJ, Pandit L, Leite MI, Asgari N, Kissani N, Hintzen R, Marignier R, Jarius S, Marcelletti J, Smith TJ, Yeaman MR, Han MH, Aktas O, Apiwattanakul M, Banwell B, Bichuetti D, Broadley S, Cabre P, Chitnis T, De Seze J, Fujihara K, Greenberg B, Hellwig K, Iorio R, Jarius S, Klawiter E, Kleiter I, Lana-Peixoto M, Nakashima , O'Connor K, Palace J, Paul F, Prayoonwiwat N, Ruprecht K, Stuve O, Tedder T, Tenembaum S, Garrahan JP, Aires B, van Herle K, van Pelt D, Villoslada P, Waubant E, Weinshenker B, Wingerchuk D, Würfel J, Zamvil S. Update on biomarkers in neuromyelitis optica. Neurology(R) neuroimmunology & neuroinflammation 2015. PMID: 26236760



  166. Kremer S, Renard F, Achard S, Lana-Peixoto MA, Palace J, Asgari N, Klawiter EC, Tenembaum SN, Banwell B, Greenberg BM, Bennett JL, Levy M, Villoslada P, Saiz A, Fujihara K, Chan KH, Schippling S, Paul F, Kim HJ, de Seze J, Wuerfel JT, Guthy-Jackson Charitable Foundation (GJCF) Neuromyelitis Optica (NMO) International Clinical Consort , Cabre P, Marignier R, Tedder T, van Pelt D, Broadley S, Chitnis T, Wingerchuk D, Pandit L, Leite MI, Apiwattanakul M, Kleiter I, Prayoonwiwat N, Han M, Hellwig K, van Herle K, John G, Hooper DC, Nakashima I, Sato D, Yeaman MR, Waubant E, Zamvil S, Stüve O, Aktas O, Smith TJ, Jacob A, O'Connor K. Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder. JAMA neurology 2015. PMID: 26010909


  167. Cantarel BL, Waubant E, Chehoud C, Kuczynski J, DeSantis TZ, Warrington J, Venkatesan A, Fraser CM, Mowry EM. Gut microbiota in multiple sclerosis: possible influence of immunomodulators. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 2015. PMID: 25775034



  168. Maghzi AH, Graves J, Revirajan N, Spain R, Liu S, McCulloch CE, Pelletier D, Green AJ, Waubant E. Retinal axonal loss in very early stages of multiple sclerosis. European journal of neurology 2015. PMID: 25929276


  169. Wilson LS, Loucks A, Gipson G, Zhong L, Bui C, Miller E, Owen M, Pelletier D, Goodin D, Waubant E, McCulloch CE. Patient preferences for attributes of multiple sclerosis disease-modifying therapies: development and results of a ratings-based conjoint analysis. International journal of MS care 2015. PMID: 25892977


  170. Weinfurtner K, Graves J, Ness J, Krupp L, Milazzo M, Waubant E. Prolonged Remission in Neuromyelitis Optica Following Cessation of Rituximab Treatment. Journal of child neurology 2014. PMID: 25387545



  171. Graves J, Grandhe S, Weinfurtner K, Krupp L, Belman A, Chitnis T, Ness J, Weinstock-Guttman B, Gorman M, Patterson M, Rodriguez M, Lotze T, Aaen G, Mowry EM, Rose JW, Simmons T, Casper TC, James J, Waubant E, US Network of Pediatric Multiple Sclerosis Centers. Protective environmental factors for neuromyelitis optica. Neurology 2014. PMID: 25339213


  172. Gourraud PA, Henry RG, Cree BA, Crane JC, Lizee A, Olson MP, Santaniello AV, Datta E, Zhu AH, Bevan CJ, Gelfand JM, Graves JS, Goodin DS, Green AJ, von Büdingen HC, Waubant E, Zamvil SS, Crabtree-Hartman E, Nelson S, Baranzini SE, Hauser SL. Precision medicine in chronic disease management: The multiple sclerosis BioScreen. Annals of neurology 2014. PMID: 25263997



  173. Ayscue P, Van Haren K, Sheriff H, Waubant E, Waldron P, Yagi S, Yen C, Clayton A, Padilla T, Pan C, Reichel J, Harriman K, Watt J, Sejvar J, Nix WA, Feikin D, Glaser C, Centers for Disease Control and Prevention (CDC). Acute flaccid paralysis with anterior myelitis - California, June 2012-June 2014. MMWR. Morbidity and mortality weekly report 2014. PMID: 25299608


  174. Casper TC, Rose JW, Roalstad S, Waubant E, Aaen G, Belman A, Chitnis T, Gorman M, Krupp L, Lotze TE, Ness J, Patterson M, Rodriguez M, Weinstock-Guttman B, Browning B, Graves J, Tillema JM, Benson L, Harris Y, US Network of Pediatric Multiple Sclerosis Centers. The US Network of Pediatric Multiple Sclerosis Centers: Development, Progress, and Next Steps. Journal of child neurology 2014. PMID: 25270659


  175. Schlaeger R, Papinutto N, Panara V, Bevan C, Lobach IV, Bucci M, Caverzasi E, Gelfand JM, Green AJ, Jordan KM, Stern WA, von Büdingen HC, Waubant E, Zhu AH, Goodin DS, Cree BA, Hauser SL, Henry RG. Spinal cord gray matter atrophy correlates with multiple sclerosis disability. Annals of neurology 2014. PMID: 25087920


  176. Maghzi AH, Revirajan N, Julian LJ, Spain R, Mowry EM, Liu S, Jin C, Green AJ, McCulloch CE, Pelletier D, Waubant E. Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis. Multiple sclerosis and related disorders 2014. PMID: 25891551


  177. Wilson L, Loucks A, Bui C, Gipson G, Zhong L, Schwartzburg A, Crabtree E, Goodin D, Waubant E, McCulloch C. Patient centered decision making: use of conjoint analysis to determine risk-benefit trade-offs for preference sensitive treatment choices. Journal of the neurological sciences 2014. PMID: 25037284



  178. Lublin FD, Reingold SC, Cohen JA, Cutter GR, Sørensen PS, Thompson AJ, Wolinsky JS, Balcer LJ, Banwell B, Barkhof F, Bebo B, Calabresi PA, Clanet M, Comi G, Fox RJ, Freedman MS, Goodman AD, Inglese M, Kappos L, Kieseier BC, Lincoln JA, Lubetzki C, Miller AE, Montalban X, O'Connor PW, Petkau J, Pozzilli C, Rudick RA, Sormani MP, Stüve O, Waubant E, Polman CH. Defining the clinical course of multiple sclerosis: the 2013 revisions. Neurology 2014. PMID: 24871874


  179. Waubant E, Maghzi AH, Revirajan N, Spain R, Julian L, Mowry EM, Marcus J, Liu S, Jin C, Green A, McCulloch CE, Pelletier D. A randomized controlled phase II trial of riluzole in early multiple sclerosis. Annals of clinical and translational neurology 2014. PMID: 25356404


  180. Kraus V, Lawson EF, von Scheven E, Tihan T, Garza J, Nathan RG, Cordoro KM, Waubant E. Atypical cases of scleroderma en coup de sabre. Journal of child neurology 2014. PMID: 24667737


  181. Graves J, Kraus V, Soares BP, Hess CP, Waubant E. Longitudinally extensive optic neuritis in pediatric patients. Journal of child neurology 2014. PMID: 24563470


  182. Beres SJ, Graves J, Waubant E. Rituximab use in pediatric central demyelinating disease. Pediatric neurology 2014. PMID: 24768216



  183. Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R, U.S. Network of Pediatric MS Centers of Excellence. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC neurology 2013. PMID: 24225378


  184. Graves J, Vinayagasundaram U, Mowry EM, Matthews IR, Marino JA, Cheng J, Waubant E. Effects of rituximab on lymphocytes in multiple sclerosis and neuromyelitis optica. Multiple sclerosis and related disorders 2013. PMID: 25878012


  185. Mowry EM, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E. Association of multiple sclerosis susceptibility variants and early attack location in the CNS. PloS one 2013. PMID: 24130718


  186. Mowry EM, Carey RF, Blasco MR, Pelletier J, Duquette P, Villoslada P, Malikova I, Roger E, Kinkel RP, McDonald J, Bacchetti P, Waubant E. Multiple sclerosis susceptibility genes: associations with relapse severity and recovery. PloS one 2013. PMID: 24130709


  187. Maghzi AH, Minagar A, Waubant E. Neuroprotection in multiple sclerosis: a therapeutic approach. CNS drugs 2013. PMID: 23955320


  188. Castillo-Trivino T, Braithwaite D, Bacchetti P, Waubant E. Rituximab in relapsing and progressive forms of multiple sclerosis: a systematic review. PloS one 2013. PMID: 23843952




  189. Chitnis T, Tardieu M, Amato MP, Banwell B, Bar-Or A, Ghezzi A, Kornberg A, Krupp LB, Pohl D, Rostasy K, Tenembaum S, Waubant E, Wassmer E. International Pediatric MS Study Group Clinical Trials Summit: meeting report. Neurology 2013. PMID: 23509048



  190. McElroy JP, Krupp LB, Johnson BA, McCauley JL, Qi Z, Caillier SJ, Gourraud PA, Yu J, Nathanson L, Belman AL, Hauser SL, Waubant E, Hedges DJ, Oksenberg JR. Copy number variation in pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2012. PMID: 23239789


  191. Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, James JA. Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis. Multiple sclerosis (Houndmills, Basingstoke, England) 2012. PMID: 23232601


  192. Julian L, Serafin D, Charvet L, Ackerson J, Benedict R, Braaten E, Brown T, O'Donnell E, Parrish J, Preston T, Zaccariello M, Belman A, Chitnis T, Gorman M, Ness J, Patterson M, Rodriguez M, Waubant E, Weinstock-Guttman B, Yeh A, Krupp LB, Network of Pediatric MS Centers of Excellence. Cognitive impairment occurs in children and adolescents with multiple sclerosis: results from a United States network. Journal of child neurology 2012. PMID: 23155206



  193. Kimbrough DJ, Fujihara K, Jacob A, Lana-Peixoto MA, Leite MI, Levy M, Marignier R, Nakashima I, Palace J, de Seze J, Stuve O, Tenembaum SN, Traboulsee A, Waubant E, Weinshenker BG, Wingerchuk DM, GJCF-CC&BR. Treatment of Neuromyelitis Optica: Review and Recommendations. Multiple sclerosis and related disorders 2012. PMID: 24555176


  194. Mowry EM, Waubant E, McCulloch CE, Okuda DT, Evangelista AA, Lincoln RR, Gourraud PA, Brenneman D, Owen MC, Qualley P, Bucci M, Hauser SL, Pelletier D. Vitamin D status predicts new brain magnetic resonance imaging activity in multiple sclerosis. Annals of neurology 2012. PMID: 22926855





  195. Waubant E, Pelletier D, Mass M, Cohen JA, Kita M, Cross A, Bar-Or A, Vollmer T, Racke M, Stüve O, Schwid S, Goodman A, Kachuck N, Preiningerova J, Weinstock-Guttman B, Calabresi PA, Miller A, Mokhtarani M, Iklé D, Murphy S, Kopetskie H, Ding L, Rosenberg E, Spencer C, Zamvil SS, ITN STAyCIS Study Group , ITN020AI Study Management Team. Randomized controlled trial of atorvastatin in clinically isolated syndrome: the STAyCIS study. Neurology 2012. PMID: 22459680


  196. Hosseini H, Mandat T, Waubant E, Agid Y, Lubetzki C, Lyon-Caen O, Stankoff B, Jedynak P, Cesaro P, Palfi S, Nguyen JP. Unilateral thalamic deep brain stimulation for disabling kinetic tremor in multiple sclerosis. Neurosurgery 2012. PMID: 21768914



  197. Langer-Gould A, Zhang JL, Chung J, Yeung Y, Waubant E, Yao J. Incidence of acquired CNS demyelinating syndromes in a multiethnic cohort of children. Neurology 2011. PMID: 21865580


  198. Teunissen CE, Tumani H, Bennett JL, Berven FS, Brundin L, Comabella M, Franciotta D, Federiksen JL, Fleming JO, Furlan R, Hintzen RQ, Hughes SG, Jimenez CR, Johnson MH, Killestein J, Krasulova E, Kuhle J, Magnone MC, Petzold A, Rajda C, Rejdak K, Schmidt HK, van Pesch V, Waubant E, Wolf C, Deisenhammer F, Giovannoni G, Hemmer B. Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies. Multiple sclerosis international 2011. PMID: 22096631


  199. Waubant E, Mowry EM, Krupp L, Chitnis T, Yeh EA, Kuntz N, Ness J, Chabas D, Strober J, McDonald J, Belman A, Milazzo M, Gorman M, Weinstock-Guttman B, Rodriguez M, Oksenberg JR, James JA, US Pediatric MS Network. Common viruses associated with lower pediatric multiple sclerosis risk. Neurology 2011. PMID: 21646624


  200. Chitnis T, Krupp L, Yeh A, Rubin J, Kuntz N, Strober JB, Chabas D, Weinstock-Guttmann B, Ness J, Rodriguez M, Waubant E. Pediatric multiple sclerosis. Neurologic clinics 2011. PMID: 21439455



  201. Castillo-Trivino T, Mowry EM, Gajofatto A, Chabas D, Crabtree-Hartman E, Cree BA, Goodin DS, Green AJ, Okuda DT, Pelletier D, Zamvil SS, Vittinghoff E, Waubant E. Switching multiple sclerosis patients with breakthrough disease to second-line therapy. PloS one 2011. PMID: 21304907


  202. Polman CH, Reingold SC, Banwell B, Clanet M, Cohen JA, Filippi M, Fujihara K, Havrdova E, Hutchinson M, Kappos L, Lublin FD, Montalban X, O'Connor P, Sandberg-Wollheim M, Thompson AJ, Waubant E, Weinshenker B, Wolinsky JS. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Annals of neurology 2011. PMID: 21387374


  203. Okuda DT, Mowry EM, Cree BA, Crabtree EC, Goodin DS, Waubant E, Pelletier D. Asymptomatic spinal cord lesions predict disease progression in radiologically isolated syndrome. Neurology 2011. PMID: 21270417



  204. Yeh EA, Waubant E, Krupp LB, Ness J, Chitnis T, Kuntz N, Ramanathan M, Belman A, Chabas D, Gorman MP, Rodriguez M, Rinker JR, Weinstock-Guttman B, National Network of Pediatric MS Centers of Excellence. Multiple sclerosis therapies in pediatric patients with refractory multiple sclerosis. Archives of neurology 2010. PMID: 21149803


  205. Mowry EM, Waubant E. Pediatric multiple sclerosis. Continuum (Minneapolis, Minn.) 2010. PMID: 22810605


  206. Mowry EM, Julian LJ, Im-Wang S, Chabas D, Galvin AJ, Strober JB, Waubant E. Health-related quality of life is reduced in pediatric multiple sclerosis. Pediatric neurology 2010. PMID: 20610119


  207. Cross AH, Waubant E. MS and the B cell controversy. Biochimica et biophysica acta 2010. PMID: 20674743


  208. Mowry EM, Krupp LB, Milazzo M, Chabas D, Strober JB, Belman AL, McDonald JC, Oksenberg JR, Bacchetti P, Waubant E. Vitamin D status is associated with relapse rate in pediatric-onset multiple sclerosis. Annals of neurology 2010. PMID: 20437559


  209. Bar-Or A, Fawaz L, Fan B, Darlington PJ, Rieger A, Ghorayeb C, Calabresi PA, Waubant E, Hauser SL, Zhang J, Smith CH. Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS? Annals of neurology 2010. PMID: 20437580


  210. Kuntz NL, Chabas D, Weinstock-Guttman B, Chitnis T, Yeh EA, Krupp L, Ness J, Rodriguez M, Waubant E, Network of US Pediatric Multiple Sclerosis Centers. Treatment of multiple sclerosis in children and adolescents. Expert opinion on pharmacotherapy 2010. PMID: 20163265


  211. Chabas D, Ness J, Belman A, Yeh EA, Kuntz N, Gorman MP, Strober JB, De Kouchkovsky I, McCulloch C, Chitnis T, Rodriguez M, Weinstock-Guttman B, Krupp LB, Waubant E, US Network of Pediatric MS Centers of Excellence. Younger children with MS have a distinct CSF inflammatory profile at disease onset. Neurology 2010. PMID: 20124205


  212. Cree B, Waubant E. Does race matter for multiple sclerosis? Neurology 2010. PMID: 20089941


  213. Yeh EA, Chitnis T, Krupp L, Ness J, Chabas D, Kuntz N, Waubant E, US Network of Pediatric Multiple Sclerosis Centers of Excellence. Pediatric multiple sclerosis. Nature reviews. Neurology 2009. PMID: 19826402


  214. Hawker K, O'Connor P, Freedman MS, Calabresi PA, Antel J, Simon J, Hauser S, Waubant E, Vollmer T, Panitch H, Zhang J, Chin P, Smith CH, OLYMPUS trial group. Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial. Annals of neurology 2009. PMID: 19847908


  215. Waubant E, Chabas D, Okuda DT, Glenn O, Mowry E, Henry RG, Strober JB, Soares B, Wintermark M, Pelletier D. Difference in disease burden and activity in pediatric patients on brain magnetic resonance imaging at time of multiple sclerosis onset vs adults. Archives of neurology 2009. PMID: 19667217



  216. Mowry EM, Beheshtian A, Waubant E, Goodin DS, Cree BA, Qualley P, Lincoln R, George MF, Gomez R, Hauser SL, Okuda DT, Pelletier D. Quality of life in multiple sclerosis is associated with lesion burden and brain volume measures. Neurology 2009. PMID: 19451531


  217. Waubant E, Chabas D. Pediatric multiple sclerosis. Current treatment options in neurology 2009. PMID: 19364455


  218. Mowry EM, Pesic M, Grimes B, Deen SR, Bacchetti P, Waubant E. Clinical predictors of early second event in patients with clinically isolated syndrome. Journal of neurology 2009. PMID: 19252775


  219. Mowry EM, Pesic M, Grimes B, Deen S, Bacchetti P, Waubant E. Demyelinating events in early multiple sclerosis have inherent severity and recovery. Neurology 2009. PMID: 19221292


  220. Okuda DT, Mowry EM, Beheshtian A, Waubant E, Baranzini SE, Goodin DS, Hauser SL, Pelletier D. Incidental MRI anomalies suggestive of multiple sclerosis: the radiologically isolated syndrome. Neurology 2008. PMID: 19073949


  221. Mowry EM, Deen S, Malikova I, Pelletier J, Bacchetti P, Waubant E. The onset location of multiple sclerosis predicts the location of subsequent relapses. Journal of neurology, neurosurgery, and psychiatry 2008. PMID: 19066192


  222. Okuda DT, Srinivasan R, Oksenberg JR, Goodin DS, Baranzini SE, Beheshtian A, Waubant E, Zamvil SS, Leppert D, Qualley P, Lincoln R, Gomez R, Caillier S, George M, Wang J, Nelson SJ, Cree BA, Hauser SL, Pelletier D. Genotype-Phenotype correlations in multiple sclerosis: HLA genes influence disease severity inferred by 1HMR spectroscopy and MRI measures. Brain : a journal of neurology 2008. PMID: 19022862


  223. Baranzini SE, Wang J, Gibson RA, Galwey N, Naegelin Y, Barkhof F, Radue EW, Lindberg RL, Uitdehaag BM, Johnson MR, Angelakopoulou A, Hall L, Richardson JC, Prinjha RK, Gass A, Geurts JJ, Kragt J, Sombekke M, Vrenken H, Qualley P, Lincoln RR, Gomez R, Caillier SJ, George MF, Mousavi H, Guerrero R, Okuda DT, Cree BA, Green AJ, Waubant E, Goodin DS, Pelletier D, Matthews PM, Hauser SL, Kappos L, Polman CH, Oksenberg JR. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. Human molecular genetics 2008. PMID: 19010793



  224. Chabas D, Castillo-Trivino T, Mowry EM, Strober JB, Glenn OA, Waubant E. Vanishing MS T2-bright lesions before puberty: a distinct MRI phenotype? Neurology 2008. PMID: 18824673


  225. Chabas D, Strober J, Waubant E. Pediatric multiple sclerosis. Current neurology and neuroscience reports 2008. PMID: 18713581


  226. Bar-Or A, Calabresi PA, Arnold D, Arnlod D, Markowitz C, Shafer S, Kasper LH, Waubant E, Gazda S, Fox RJ, Panzara M, Sarkar N, Agarwal S, Smith CH. Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial. Annals of neurology 2008. PMID: 18383069


  227. Waubant E. Spotlight on anti-CD20. International MS journal 2008. PMID: 18713565


  228. Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, Fox RJ, Bar-Or A, Panzara M, Sarkar N, Agarwal S, Langer-Gould A, Smith CH, HERMES Trial Group. B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. The New England journal of medicine 2008. PMID: 18272891



  229. Banwell B, Krupp L, Kennedy J, Tellier R, Tenembaum S, Ness J, Belman A, Boiko A, Bykova O, Waubant E, Mah JK, Stoian C, Kremenchutzky M, Bardini MR, Ruggieri M, Rensel M, Hahn J, Weinstock-Guttman B, Yeh EA, Farrell K, Freedman M, Iivanainen M, Sevon M, Bhan V, Dilenge ME, Stephens D, Bar-Or A. Clinical features and viral serologies in children with multiple sclerosis: a multinational observational study. The Lancet. Neurology 2007. PMID: 17689148


  230. Kantor AB, Deng J, Waubant E, Lin H, Becker CH, Lacy JR, Perrone AM, Bennett D, Goelz SE. Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling. Journal of neuroimmunology 2007. PMID: 17614141


  231. Waubant E. Emerging therapies for MS. Revue neurologique 2007. PMID: 17607191


  232. Belman AL, Chitnis T, Renoux C, Waubant E, International Pediatric MS Study Group. Challenges in the classification of pediatric multiple sclerosis and future directions. Neurology 2007. PMID: 17438242


  233. West T, Wyatt M, High A, Bostrom A, Waubant E. Are initial demyelinating event recovery and time to second event under differential control? Neurology 2006. PMID: 16966542





  234. Waubant E, Sadovnick AD. Interferon beta babies. Neurology 2005. PMID: 16186513


  235. Cree BA, Lamb S, Morgan K, Chen A, Waubant E, Genain C. An open label study of the effects of rituximab in neuromyelitis optica. Neurology 2005. PMID: 15824362


  236. Waubant E, Tezenas du Montcel S, Jedynak C, Obadia M, Hosseini H, Damier P, Lubetzki C, Agid Y, Degos JD. Multiple sclerosis tremor and the Stewart-Holmes manoeuvre. Movement disorders : official journal of the Movement Disorder Society 2003. PMID: 12889088


  237. Waubant E, Vukusic S, Gignoux L, Dubief FD, Achiti I, Blanc S, Renoux C, Confavreux C. Clinical characteristics of responders to interferon therapy for relapsing MS. Neurology 2003. PMID: 12874396



  238. Waubant E, Goodkin D, Bostrom A, Bacchetti P, Hietpas J, Lindberg R, Leppert D. IFNbeta lowers MMP-9/TIMP-1 ratio, which predicts new enhancing lesions in patients with SPMS. Neurology 2003. PMID: 12525717


  239. Waubant E, Hietpas J, Stewart T, Dyme Z, Herbert J, Lacy J, Miller C, Rensel M, Schwid S, Goodkin D. Interferon beta-1a in children with multiple sclerosis is well tolerated. Neuropediatrics 2001. PMID: 11571702




  240. Suhy J, Rooney WD, Goodkin DE, Capizzano AA, Soher BJ, Maudsley AA, Waubant E, Andersson PB, Weiner MW. 1H MRSI comparison of white matter and lesions in primary progressive and relapsing-remitting MS. Multiple sclerosis (Houndmills, Basingstoke, England) 2000. PMID: 10871825


  241. Kita M, Goodkin DE, Bacchetti P, Waubant E, Nelson SJ, Majumdar S. Magnetization transfer ratio in new MS lesions before and during therapy with IFNbeta-1a. Neurology 2000. PMID: 10802778