Taylor LaFlam, MD, PhD

Dr. LaFlam is a basic science researcher who studies immune tolerance and the pathogenesis of lupus and related diseases. His work examines the role of B cells, including plasma cells, in this process. A particular focus is the P2RY8 receptor pathway, which helps regulate proliferation and migration of immune cells such as germinal center B cells. He also investigates the genetics of lupus.

  1. Hurabielle C, LaFlam TN, Gearing M, Ye CJ. Functional genomics in inborn errors of immunity. Volume 322 of Issue 1. Immunological reviews 2024. PMID: 38329267


  2. Chang A, Cabana MD, LaFlam TN, Patel S, Okumura M. Early Peanut Introduction and Testing: A Framework for General Pediatrician Beliefs and Practices. Pediatric allergy, immunology, and pulmonology 2020. PMID: 34143689


  3. LaFlam TN, Phelps A, Choi WT, Kornblith AE. Meckel Diverticulum Presenting as Abdominal Pain and Subsequent Bowel Perforation. The Journal of emergency medicine 2020. PMID: 32317193


  4. Angela Chang, Michael Cabana, Saharsh Patel, Taylor Laflam, Megumi Okumura. General Pediatrician Beliefs and Practices about Early Peanut Introduction: An Opportunity for Allergists to Engage Community Pediatricians. Journal of Allergy and Clinical Immunology 2018. PMID:


  5. LaFlam TN, Seumois G, Miller CN, Lwin W, Fasano KJ, Waterfield M, Proekt I, Vijayanand P, Anderson MS. Identification of a novel cis-regulatory element essential for immune tolerance. The Journal of experimental medicine 2015. PMID: 26527800


  6. Baravalle G, Greer AM, LaFlam TN, Shin JS. Antigen-conjugated human IgE induces antigen-specific T cell tolerance in a humanized mouse model. Volume 192 of Issue 7. Journal of immunology (Baltimore, Md. : 1950) 2014. PMID: 24610015


  7. Parent AV, Russ HA, Khan IS, LaFlam TN, Metzger TC, Anderson MS, Hebrok M. Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development. Volume 13 of Issue 2. Cell stem cell 2013. PMID: 23684540


  8. Renner ED, Torgerson TR, Rylaarsdam S, Añover-Sombke S, Golob K, LaFlam T, Zhu Q, Ochs HD. STAT3 mutation in the original patient with Job's syndrome. Volume 357 of Issue 16. The New England journal of medicine 2007. PMID: 17942886