Elliott Vichinsky, MD

SUMMARY OF INTERESTS:
Protecting and advancing the health and well-being of children through clinical care, teaching, and research; hematology; hemoglobin, hemoglobin disorders; designing and leading clinical research studies; understanding the pathophysiology of hemoglobinopathies; comprehensive clinical care; evaluating therapeutic interventions to improve disease outcomes; expanding patient access to quality healthcare; improving patient quality of life; health equity; establishing, improving, and expanding networks of care for hemoglobinopathy patients; designing and leading collaborative multi-center trials; forming and leading regional, national, and international collaborative research networks; implementation studies; data collection; registry and surveillance systems for hemoglobinopathies; expanding enrollment in clinical trials; accelerating the pace of clinical research; writing, editing, and reviewing grant applications, abstracts, peer-reviewed manuscripts, chapters, and books; publishing research findings; presenting research findings to diverse audiences; developing, updating, publishing, and teaching standards of care guidelines for optimal management of hemoglobinopathy patients; training and expanding the healthcare workforce knowledgeable in the standard of care treatments; developing and teaching academic curricula; junior and mid-career faculty career development; recruiting and mentoring under-represented faculty in medicine and science; diversity in medicine and research; mentoring others to become leading independent clinician scientists equipped to advance the field; sickle cell disease; sickle cell anemia; sickle cell trait; pain management; acute chest syndrome; avascular necrosis; bone disease; organ failure; priapism; pulmonary hypertension; hemolysis; alloimmunization; iron dysregulation; brain iron; chelation therapy, neurodegeneration; NBIA; PKAN; thalassemia syndromes; alpha thalassemia major; fetal hemoglobin; in utero transfusion, intrauterine stem cell transplantation; Bart's fetalis syndrome; stroke; transcranial doppler; TCD screening; prenatal and newborn screening; genetic counseling; BMT; gene and stem cell therapy; red blood cell biology; laboratory medicine; pheresis medicine; transfusion medicine; global medicine; political advocacy to improve healthcare policy; collaborating with community advisory boards and involving them as part of the research team to ensure our research activities are guided by the needs and concerns of people affected.

I am an endowed physician and professor in residence at the University of California San Francisco Benioff Children's Hospital in Oakland, California. For nearly 40 years I have been on forefront of research into better treatments and potential cures for hemoglobinopathies. My directorship of the largest and most comprehensive program for individuals with sickle cell disease and their families in the western United States began in 1978. Renamed the UCSF Sickle Cell Center of Excellence and rebuilt stronger, my center continues its mission to improve clinical outcomes and quality of life for individuals living with sickle cell and their families across the lifespan.

I direct the Hemoglobinopathy Reference Laboratory for the State of California at UCSF Benioff Children's Hospital Oakland, which has been a national resource to aid in the diagnosis of clinically relevant hemoglobinopathies since 1973 (the laboratory has been a vital component of the state's newborn screening follow-up program, evaluating clinically relevant hemoglobin variants, providing confirmatory testing on all newborns in California with presumptive sickle cell disease, beta thalassemia or HbH disease, and assisting NBS programs across the country.

Throughout my career I have developed successful teams that bring basic and clinical investigators together in partnership with the biomedical and pharmaceutical industry to develop and evaluate new treatments for hemoglobinopathies. I was lead investigator of the safety and efficacy of several important therapies for sickle cell disease, such as arginine, mitapivat, and other promising drug trials. I was the senior/principal author of the drug trials of voxelotor and glutamine and played a pivotal role securing their FDA-approval.

In addition to leading the development of novel therapeutics, I serve as PI or Co-PI on several key evidence-based clinical research networks, such as the American Society of Hematology’s Research Collaborative (as the Western States Sickle Cell Disease Clinical Trials Network); the NHLBI’s SC-Links study (Linking the Sickle Cell Community, Providers and Systems to Improve Sickle Cell Disease Care (SCDIC); the NHLBI’s REDS-IV-P study (Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric, Domestic Hubs); the Network for California Sickle Cell Care and HRSA’s Pacific Sickle Cell Regional Collaboration, which aims to reduce morbidity and mortality by improving the quality of coordinated and comprehensive services to individuals with sickle cell disease and their families. These networks link together researchers, clinicians, and communities affected by sickle cell disease to guide evidence-based treatment and improve patient care.

I am commitment to fostering the next generation of translational and clinical scientists and guide the academic development of my colleagues through participation in programs like the American Society of Pediatric Hematology Oncology’s Mid-Career Mentoring Program, the Doris Duke Charitable Foundation’s Clinical Research Mentorship Program, and the NIH’s Mentored Research Scientist Career Development Program (K series). I have supported young students from disadvantaged backgrounds explore potential career opportunities in healthcare and science through my involvement in the UCSF Summer Student Program.

I am a passionate advocate to improve healthcare policies for people living with sickle cell disease. Over the years I have provided scientific insight and medical expertise to legislators and health care policy makers at the regional, state, and federal levels of government, including my work with California Congresswoman Barbara Lee, State Superintendent of Public Instruction Tony Thurmond, California Assemblymember Mike Gibson, the California State Health Subcommittee, and multiple mayoral leaders of the City of Oakland, California to improve and increase access to comprehensive care for Californians living with sickle cell disease.
Education
Senior Research Fellow, 1979 - Dept of Pediatrics and Medicine, University of Washington, Seattle, WA
Fellowship, 1978 - Pediatrics, Children's Orthopedic Hospital and Medical Center, Seattle, WA
Internship, 1975 - Pediatrics, Children's Orthopedic Hospital and Medical Center, Seattle, WA
M.D., 1974 - School of Medicine, State University of New York Downstate
B.S., 1970 - Biology, University of Wisconsin, Madison
Honors and Awards
  • Award of Distinction: "Celebrating Sickle Cell's Giants, Pioneers, and Visionaries", 15th Annual Sickle Cell Disease Educational Summit. Cayenne Wellness Center. Sept 13-16 2023. Los An, 2023
  • Distinguished Career Award, American Society of Pediatric Hematology Oncology (ASPHO), 2019
  • UCSF Benioff Chilldren’s Hospital Endowed Clinical Care Professorship, UCSF Benioff Chilldren’s Hospital, 2019
  • Pioneer Award, Sickle Cell Disease Association of America (SCDAA), 2013
  • Distinguished Leadership as Chair of the Medical Advisory Board, Cooley's Anemia Foundation, 2009
  • Distinguished Leadership Award, Cooley's Anemia Foundation Medical Advisory Board, 2009
  • Charles F. Whitten, M.D. Lecture Award, Sickle Cell Disease Assocation of America (SCDAA) and the NHLBI, 2007
  • Lifetime Achievement Award, Sickle Cell Disease Foundation of California, 2007
  • Grateful Families Award, UCSF Benioff Children's Hospital Oakland, 2007
  • Bronze Bambino Lifetime Achievement Award, Children's Hospital & Research Center Oakland, 2005
  • Patient Commitment Award, Sickle Cell Community Health Network of Northern California, 2004
  • Patient Appreciation Award, Thalassemia Action Group, 2003
  • Social Worker's Award, UCSF Benioff Children's Hospital Oakland, 2003
  • Scientific Achievement Award, UCSF Benioff Children's Hospital Oakland, 2000
  • Senior Scientist Award, UCSF Benioff Children's Hospital Oakland, 1997
  • Cooley's Anemia Award, Cooley's Anemia Foundation, 1996
  • Miracle Maker Award, Children's Miracle Network, 1995
  • Alpha Omega Award, Alpha Omega Alpha Honor Society, 1974
  • Cum Laude, State University of New York Downstate, 1974
  • Cum Laude, University of Wisconsin, 1970
Websites

  1. Rees CA, Brousseau DC, Cohen DM, Villella A, Dampier C, Brown K, Campbell A, Chumpitazi CE, Airewele G, Chang T, Denton C, Ellison A, Thompson A, Ahmad F, Bakshi N, Coleman KD, Leibovich S, Leake D, Hatabah D, Wilkinson H, Robinson M, Casper TC, Vichinsky E, Morris CR, SCD Arginine Study Group and PECARN. Sickle Cell Disease Treatment with Arginine Therapy (STArT): study protocol for a phase 3 randomized controlled trial. Trials 2023. PMID: 37587492


  2. Sayani FA, Singer ST, Carlberg KT, Vichinsky EP. Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia. Hematology/oncology clinics of North America 2023. PMID: 36907611


  3. Lal A, Vichinsky E. The Clinical Phenotypes of Alpha Thalassemia. Hematology/oncology clinics of North America 2023. PMID: 36907606


  4. Vissa M, Larkin SK, Vichinsky EP, Kuypers FA, Soupene E. Assessment of total and unbound cell-free heme in plasma of patients with sickle cell disease. Experimental biology and medicine (Maywood, N.J.) 2023. PMID: 36941786


  5. Paulukonis ST, Snyder A, Smeltzer MP, Sutaria AN, Hurden I, Latta K, Chennuri S, Vichinsky E, Reeves SL. COVID-19 Infection and Outcomes in Newborn Screening Cohorts of Sickle Cell Trait and Sickle Cell Disease in Michigan and Georgia. Journal of pediatric hematology/oncology 2023. PMID: 37083273


  6. MacKenzie TC, Schwab ME, Lianoglou BR, Gano D, Gonzalez J, Arvon RL, Baschat AA, Bianchi DW, Bitanga M, Bourguignon A, Brown RN, Chen B, Chien M, Davis-Nelson S, de Laat MWM, Ekwattanakit S, Gollin Y, Hirata G, Jelin A, Jolley J, Meyer P, Miller J, Norton ME, Ogasawara KK, Panchalee T, Schindewolf E, Shaw SW, Stumbaugh TL, Thompson AA, Towner D, Tsai PS, Viprakasit V, Volanakis E, Vichinsky E, Allen IE, Zhang L. The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry. Blood advances 2022. PMID: 36306387


  7. Vitrano A, Musallam KM, Meloni A, Karimi M, Daar S, Ricchi P, Costantini S, Vlachaki E, Di Marco V, El-Beshlawy A, Hajipour M, Ansari SH, Filosa A, Ceci A, Singer ST, Naserullah ZA, Pepe A, Cademartiri F, Pollina SA, Scondotto S, Dardanoni G, Bonifazi F, Sankaran VG, Vichinsky E, Taher AT, Maggio A, International Working Group on Thalassemia (IWG-THAL). Development of a Thalassemia International Prognostic Scoring System (TIPSS). Blood cells, molecules & diseases 2022. PMID: 36463683


  8. Kuo KHM, Layton DM, Lal A, Al-Samkari H, Bhatia J, Kosinski PA, Tong B, Lynch M, Uhlig K, Vichinsky EP. Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent a-thalassaemia or �-thalassaemia: an open-label, multicentre, phase 2 study. Lancet (London, England) 2022. PMID: 35964609


  9. Walter PB, Hohman LS, Rokeby A, Lum JJ, Hagar R, Lavrisha L, Saulys A, Kuypers FA, Vichinsky E, Morris CR. The effects of glutamine supplementation on markers of apoptosis and autophagy in sickle cell disease peripheral blood mononuclear cells. Volume 70. Complementary therapies in medicine 2022. PMID: 35843474


  10. Shah NR, Treadwell MJ, Vichinsky E. Transitioning Adolescents With Sickle Cell Disease From Pediatric to Adult Care: Results From a New Survey of Health Care Professionals. 2022. PMID: 35700397


  11. Morris CR, Kuypers FA, Hagar R, Larkin S, Lavrisha L, Saulys A, Vichinsky EP, Suh JH. Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study. Volume 64. Complementary therapies in medicine 2022. PMID: 35032556


  12. MacKenzie TC, Amid A, Angastiniotis M, Butler C, Gilbert S, Gonzalez J, Keller RL, Kharbanda S, Kirby-Allen MA, Koenig BA, Kyono W, Lal A, Lianoglou BR, Norton ME, Ogasawara KK, Panchalee T, Rosner M, Schwab ME, Thompson AA, Waye JS, Vichinsky E. Consensus statement for the perinatal management of patients with alpha thalassemia major. 2021. PMID: 34749399


  13. Musallam KM, Vitrano A, Meloni A, Pollina SA, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Ansari SH, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Bonifazi F, Sankaran VG, Vichinsky E, Taher AT, Maggio A, International Working Group on Thalassemia (IWG-THAL). Risk of mortality from anemia and iron overload in nontransfusion-dependent β-thalassemia. Volume 97 of Issue 2. American journal of hematology 2021. PMID: 34862982


  14. Chapin J, Cohen AR, Neufeld EJ, Vichinsky E, Giardina PJ, Boudreaux J, Le BC, Kenney K, Trimble S, Thompson AA. An update on the US adult thalassaemia population: a report from the CDC thalassaemia treatment centres. Volume 196 of Issue 2. British journal of haematology 2021. PMID: 34775608


  15. Berliner C, Wang ZJ, Singer ST, Grosse R, McDonough RV, Padua E, Yuan Q, Weyhmiller M, James E, Vichinsky E, Adam G, Yamamura J, Bannas P, Fischer R, Schoennagel BP. Anterior Pituitary Volume in Patients with Transfusion Dependent Anemias: Volumetric Approaches and Relation to Pituitary MRI‑R2. Volume 32 of Issue 1. Clinical neuroradiology 2021. PMID: 34709410


  16. Musallam KM, Vitrano A, Meloni A, Addario Pollina S, Di Marco V, Hussain Ansari S, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Karimi M, El-Beshlawy A, Hajipour M, Bonifazi F, Vichinsky E, Taher AT, Sankaran VG, Maggio A, International Working Group on Thalassemia (IWG-THAL). Primary HBB gene mutation severity and long-term outcomes in a global cohort of β-thalassaemia. Volume 196 of Issue 2. British journal of haematology 2021. PMID: 34697800


  17. Musallam KM, Vitrano A, Meloni A, Pollina SA, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Ansari SH, Filosa A, Ricchi P, Ceci A, Daar S, Vlachaki E, Singer ST, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Bonifazi F, Sankaran VG, Vichinsky E, Taher AT, Maggio A. Survival and causes of death in 2,033 patients with non-transfusion-dependent β-thalassemia Volume 106 of Issue 9. Haematologica 2021. PMID: 33882642


  18. Lal A, Wong T, Keel S, Pagano M, Chung J, Kamdar A, Rao L, Ikeda A, Puthenveetil G, Shah S, Yu J, Vichinsky E. The transfusion management of beta thalassemia in the United States. 2021. PMID: 34453453


  19. Ballas SK, Kuypers FA, Gordeuk VR, Hankins JS, Thompson AA, Vichinsky E. Time to rethink haemoglobin threshold guidelines in sickle cell disease. Volume 195 of Issue 4. British journal of haematology 2021. PMID: 34131897


  20. Singer ST, Fischer R, Allen I, Lal A, Vichinsky E, Yuan Q, Wang ZJ. Pituitary iron and factors predictive of fertility status in transfusion dependent thalassemia. 2021. PMID: 33121232


  21. Friedman D, Dozor AJ, Milner J, D'Souza M, Talano JA, Moore TB, Shenoy S, Shi Q, Walters MC, Vichinsky E, Parsons SK, Braniecki S, Moorthy CR, Ayello J, Flower A, Morris E, Mahanti H, Fabricatore S, Klejmont L, van de Ven C, Baxter-Lowe LA, Cairo MS. Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation. Volume 56 of Issue 9. Bone marrow transplantation 2021. PMID: 33958740


  22. Howard J, Ataga KI, Brown RC, Achebe M, Nduba V, El-Beshlawy A, Hassab H, Agodoa I, Tonda M, Gray S, Lehrer-Graiwer J, Vichinsky E. Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial. Volume 8 of Issue 5. The Lancet. Haematology 2021. PMID: 33838113


  23. Vissa M, Vichinsky E. Voxelotor for the treatment of sickle cell disease. Volume 14 of Issue 3. Expert review of hematology 2021. PMID: 33602029


  24. Tong S, Vichinsky E. Iron Deficiency: Implications Before Anemia. Volume 42 of Issue 1. Pediatrics in review 2021. PMID: 33386301


  25. Vitrano A, Meloni A, Addario Pollina W, Karimi M, El-Beshlawy A, Hajipour M, Di Marco V, Hussain Ansari S, Filosa A, Ricchi P, Ceci A, Daar S, Titi Singer S, Naserullah ZA, Pepe A, Scondotto S, Dardanoni G, Bonifazi F, Vichinsky E, Maggio A. A complication risk score to evaluate clinical severity of thalassaemia syndromes. Volume 192 of Issue 3. British journal of haematology 2020. PMID: 33216983


  26. Abrams DI, Couey P, Dixit N, Sagi V, Hagar W, Vichinsky E, Kelly ME, Connett JE, Gupta K. Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial. 2020. PMID: 32678452


  27. DeBaun MR, Jordan LC, King AA, Schatz J, Vichinsky E, Fox CK, McKinstry RC, Telfer P, Kraut MA, Daraz L, Kirkham FJ, Murad MH. American Society of Hematology 2020 guidelines for sickle cell disease: prevention, diagnosis, and treatment of cerebrovascular disease in children and adults. Volume 4 of Issue 8. Blood advances 2020. PMID: 32298430


  28. Kelly S, Jacobs ES, Stone M, Keating SM, Lee TH, Chafets D, Heitman J, Dimapasoc M, Operskalski E, Hagar W, Vichinsky E, Busch MP, Norris PJ, Custer B, Recipient Epidemiology and Donor Evaluation Study (REDS-III). Influence of sickle cell disease on susceptibility to HIV infection. Volume 15 of Issue 4. PloS one 2020. PMID: 32267841


  29. Ruhl AP, Sadreameli SC, Allen JL, Bennett DP, Campbell AD, Coates TD, Diallo DA, Field JJ, Fiorino EK, Gladwin MT, Glassberg JA, Gordeuk VR, Graham LM, Greenough A, Howard J, Kato GJ, Knight-Madden J, Kopp BT, Koumbourlis AC, Lanzkron SM, Liem RI, Machado RF, Mehari A, Morris CR, Ogunlesi FO, Rosen CL, Smith-Whitley K, Tauber D, Terry N, Thein SL, Vichinsky E, Weir NA, Cohen RT, Klings ES. Identifying Clinical and Research Priorities in Sickle Cell Lung Disease. An Official American Thoracic Society Workshop Report. Volume 16 of Issue 9. Annals of the American Thoracic Society 2019. PMID: 31469310


  30. Klopstock T, Tricta F, Neumayr L, Karin I, Zorzi G, Fradette C, Kmiec T, Büchner B, Steele HE, Horvath R, Chinnery PF, Basu A, Küpper C, Neuhofer C, Kálmán B, Dušek P, Yapici Z, Wilson I, Zhao F, Zibordi F, Nardocci N, Aguilar C, Hayflick SJ, Spino M, Blamire AM, Hogarth P, Vichinsky E. Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study. Volume 18 of Issue 7. The Lancet. Neurology 2019. PMID: 31202468


  31. Vichinsky E, Hoppe CC, Ataga KI, Ware RE, Nduba V, El-Beshlawy A, Hassab H, Achebe MM, Alkindi S, Brown RC, Diuguid DL, Telfer P, Tsitsikas DA, Elghandour A, Gordeuk VR, Kanter J, Abboud MR, Lehrer-Graiwer J, Tonda M, Intondi A, Tong B, Howard J, HOPE Trial Investigators. A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease. Volume 381 of Issue 6. The New England journal of medicine 2019. PMID: 31199090


  32. Michlitsch J, Larkin S, Vichinsky E, Kuypers FA. Vincristine-induced anemia in hereditary spherocytosis. 2019. PMID: 31161774


  33. Akbari M, Patel R, Carrao V, Hagar W, Vichinsky E, Chuang SK. Evaluation of Mandible Fractures in Patients With Sickle Cell Anemia-A Nationwide Study. Volume 77 of Issue 7. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 2019. PMID: 30707980


  34. Lal A, Wong TE, Andrews J, Balasa VV, Chung JH, Forester CM, Ikeda AK, Keel SB, Pagano MB, Puthenveetil G, Shah SJ, Yu JC, Vichinsky EP. Transfusion practices and complications in thalassemia. 2018. PMID: 30260477


  35. Niihara Y, Miller ST, Kanter J, Lanzkron S, Smith WR, Hsu LL, Gordeuk VR, Viswanathan K, Sarnaik S, Osunkwo I, Guillaume E, Sadanandan S, Sieger L, Lasky JL, Panosyan EH, Blake OA, New TN, Bellevue R, Tran LT, Razon RL, Stark CW, Neumayr LD, Vichinsky EP, Investigators of the Phase 3 Trial of l-Glutamine in Sickle Cell Disease. A Phase 3 Trial of l-Glutamine in Sickle Cell Disease. Volume 379 of Issue 3. The New England journal of medicine 2018. PMID: 30021096


  36. Thompson AA, Walters MC, Kwiatkowski J, Rasko JEJ, Ribeil JA, Hongeng S, Magrin E, Schiller GJ, Payen E, Semeraro M, Moshous D, Lefrere F, Puy H, Bourget P, Magnani A, Caccavelli L, Diana JS, Suarez F, Monpoux F, Brousse V, Poirot C, Brouzes C, Meritet JF, Pondarré C, Beuzard Y, Chrétien S, Lefebvre T, Teachey DT, Anurathapan U, Ho PJ, von Kalle C, Kletzel M, Vichinsky E, Soni S, Veres G, Negre O, Ross RW, Davidson D, Petrusich A, Sandler L, Asmal M, Hermine O, De Montalembert M, Hacein-Bey-Abina S, Blanche S, Leboulch P, Cavazzana M. Gene Therapy in Patients with Transfusion-Dependent β-Thalassemia. Volume 378 of Issue 16. The New England journal of medicine 2018. PMID: 29669226


  37. Vichinsky E, Cohen A, Thompson AA, Giardina PJ, Lal A, Paley C, Cheng WY, McCormick N, Sasane M, Qiu Y, Kwiatkowski JL. Epidemiologic and clinical characteristics of nontransfusion-dependent thalassemia in the United States. 2018. PMID: 29637688


  38. Carlberg KT, Singer ST, Vichinsky EP. Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia. Volume 32 of Issue 2. Hematology/oncology clinics of North America 2018. PMID: 29458733


  39. Kato GJ, Piel FB, Reid CD, Gaston MH, Ohene-Frempong K, Krishnamurti L, Smith WR, Panepinto JA, Weatherall DJ, Costa FF, Vichinsky EP. Sickle cell disease. Volume 4. Nature reviews. Disease primers 2018. PMID: 29542687


  40. Khurana M, Fung EB, Vichinsky EP, Theil EC. Dietary nonheme iron is equally bioavailable from ferritin or ferrous sulfate in thalassemia intermedia. Volume 34 of Issue 8. Pediatric hematology and oncology 2017. PMID: 29232169


  41. Vichinsky E. Chronic organ failure in adult sickle cell disease. Volume 2017 of Issue 1. Hematology. American Society of Hematology. Education Program 2017. PMID: 29222290


  42. Serjeant GR, Vichinsky E. Variability of homozygous sickle cell disease: The role of alpha and beta globin chain variation and other factors. Volume 70. Blood cells, molecules & diseases 2017. PMID: 28689691


  43. Winstead M, Sun PP, Martin K, Earl J, Neumayr L, Hoppe C, Vichinsky E. Encephaloduroarteriosynangiosis (EDAS) in young patients with cerebrovascular complications of sickle cell disease: Single-institution experience. Volume 34 of Issue 2. Pediatric hematology and oncology 2017. PMID: 28532265


  44. Minniti CP, Vichinsky E. Lifespan care in SCD: Whom to transition, the patients or the health care system? Volume 92 of Issue 6. American journal of hematology 2017. PMID: 28211097


  45. Hoppe C, Jacob E, Styles L, Kuypers F, Larkin S, Vichinsky E. Simvastatin reduces vaso-occlusive pain in sickle cell anaemia: a pilot efficacy trial. Volume 177 of Issue 4. British journal of haematology 2017. PMID: 28369718


  46. Vichinsky E, El-Beshlawy A, Al Zoebie A, Kamdem A, Koussa S, Chotsampancharoen T, Bruederle A, Gilotti G, Han J, Elalfy M. Long-term safety and efficacy of deferasirox in young pediatric patients with transfusional hemosiderosis: Results from a 5-year observational study (ENTRUST). Volume 64 of Issue 9. Pediatric blood & cancer 2017. PMID: 28296163


  47. Field JJ, Majerus E, Ataga KI, Vichinsky EP, Schaub R, Mashal R, Nathan DG. NNKTT120, an anti-iNKT cell monoclonal antibody, produces rapid and sustained iNKT cell depletion in adults with sickle cell disease. Volume 12 of Issue 2. PloS one 2017. PMID: 28152086


  48. Paulukonis ST, Feuchtbaum LB, Coates TD, Neumayr LD, Treadwell MJ, Vichinsky EP, Hulihan MM. Emergency department utilization by Californians with sickle cell disease, 2005-2014. 2016. PMID: 28000344


  49. Kreger EM, Singer ST, Witt RG, Sweeters N, Lianoglou B, Lal A, Mackenzie TC, Vichinsky E. Favorable outcomes after in utero transfusion in fetuses with alpha thalassemia major: a case series and review of the literature. 2016. PMID: 27862048


  50. Neumayr L, Vichinsky E. Stroke recurrence in adult sickle cell patients: it is time for action! Volume 56 of Issue 5. Transfusion 2016. PMID: 27167352


  51. Vichinsky E. Non-transfusion-dependent thalassemia and thalassemia intermedia: epidemiology, complications, and management. Volume 32 of Issue 1. Current medical research and opinion 2015. PMID: 26479125


  52. Singer ST, Killilea D, Suh JH, Wang ZJ, Yuan Q, Ivani K, Evans P, Vichinsky E, Fischer R, Smith JF. Fertility in transfusion-dependent thalassemia men: effects of iron burden on the reproductive axis. Volume 90 of Issue 9. American journal of hematology 2015. PMID: 26044409


  53. Morris CR, Kim HY, Klings ES, Wood J, Porter JB, Trachtenberg F, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Hassell K, Taher A, Neufeld EJ, Thompson AA, Larkin S, Suh JH, Vichinsky EP, Kuypers FA, Thalassemia Clinical Research Network. Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia. Volume 169 of Issue 6. British journal of haematology 2015. PMID: 25907665


  54. Ballas SK, Vichinsky EP. Is the medical home for adult patients with sickle cell disease a reality or an illusion? Volume 39 of Issue 2. Hemoglobin 2015. PMID: 25806421


  55. Derderian SC, Jeanty C, Walters MC, Vichinsky E, MacKenzie TC. In utero hematopoietic cell transplantation for hemoglobinopathies. Volume 5. Frontiers in pharmacology 2015. PMID: 25628564


  56. Porter JB, Walter PB, Neumayr LD, Evans P, Bansal S, Garbowski M, Weyhmiller MG, Harmatz PR, Wood JC, Miller JL, Byrnes C, Weiss G, Seifert M, Grosse R, Grabowski D, Schmidt A, Fischer R, Nielsen P, Niemeyer C, Vichinsky E. Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients. British journal of haematology 2014. PMID: 25209728


  57. Paulukonis ST, Harris WT, Coates TD, Neumayr L, Treadwell M, Vichinsky E, Feuchtbaum LB. Population based surveillance in sickle cell disease: methods, findings and implications from the California registry and surveillance system in hemoglobinopathies project (RuSH). 2014. PMID: 25176145


  58. Vichinsky, Elliott P., ed.. Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease Hematology/oncology clinics of North America 2014. PMID:


  59. Trachtenberg FL, Gerstenberger E, Xu Y, Mednick L, Sobota A, Ware H, Thompson AA, Neufeld EJ, Yamashita R, Thalassemia Clinical Research Network. Relationship among chelator adherence, change in chelators, and quality of life in thalassemia. Volume 23 of Issue 8. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2014. PMID: 24682717


  60. Singer ST, Kuypers F, Fineman J, Gildengorin G, Larkin S, Sweeters N, Rosenfeld H, Kurio G, Higa A, Jeng M, Huang J, Vichinsky EP. Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy. Annals of hematology 2014. PMID: 24577514


  61. Mackin RS, Insel P, Truran D, Vichinsky EP, Neumayr LD, Armstrong FD, Gold JI, Kesler K, Brewer J, Weiner MW, Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group. Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition. Volume 82 of Issue 10. Neurology 2014. PMID: 24523480


  62. Klings ES, Vichinsky EP, Morris CR. Response to "efficacy and safety of sildenafil for the treatment of severe pulmonary hypertension in patients with hemoglobinopathies: results from a long-term follow up " Haematologica 2014;99(2):e17-18. Volume 99 of Issue 2. Haematologica 2014. PMID: 24497564


  63. Vichinsky EP. Emerging therapy in hemoglobinopathies: lessons from the past and optimism for the future. Volume 28 of Issue 2. Hematology/oncology clinics of North America 2014. PMID: 24589274


  64. Klaassen RJ, Barrowman N, Merelles-Pulcini M, Vichinsky EP, Sweeters N, Kirby-Allen M, Neufeld EJ, Kwiatkowski JL, Wu J, Vickars L, Blanchette VS, Forgie M, Yamashita R, Wong-Rieger D, Young NL. Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major. Volume 164 of Issue 3. British journal of haematology 2013. PMID: 24180641


  65. Oliveros O, Trachtenberg F, Haines D, Gerstenberger E, Martin M, Carson S, Green S, Calamaras D, Hess P, Yamashita R, Vichinsky E, Thalassemia Clinical Research Network. Pain over time and its effects on life in thalassemia. Volume 88 of Issue 11. American journal of hematology 2013. PMID: 23918696


  66. Marsh A, Golden C, Hoppe C, Quirolo K, Vichinsky E. Renal medullary carcinoma in an adolescent with sickle cell anemia. Volume 61 of Issue 3. Pediatric blood & cancer 2013. PMID: 24108577


  67. Vichinsky E, Torres M, Minniti CP, Barrette S, Habr D, Zhang Y, Files B, study CICL670A2201 investigators. Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea. Volume 88 of Issue 12. American journal of hematology 2013. PMID: 23946212


  68. Fung EB, Kwiatkowski JL, Huang JN, Gildengorin G, King JC, Vichinsky EP. Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial. 2013. PMID: 23945720


  69. Pratini NR, Sweeters N, Vichinsky E, Neufeld JA. Treatment of classic pantothenate kinase-associated neurodegeneration with deferiprone and intrathecal baclofen. Volume 92 of Issue 8. American journal of physical medicine & rehabilitation 2013. PMID: 23370589


  70. Vichinsky E, Neumayr L, Trimble S, Giardina PJ, Cohen AR, Coates T, Boudreaux J, Neufeld EJ, Kenney K, Grant A, Thompson AA, CDC Thalassemia Investigators. Transfusion complications in thalassemia patients: a report from the Centers for Disease Control and Prevention (CME). Volume 54 of Issue 4. Transfusion 2013. PMID: 23889533


  71. Thompson AA, Kim HY, Singer ST, Vichinsky E, Eile J, Yamashita R, Giardina PJ, Olivieri N, Parmar N, Trachtenberg F, Neufeld EJ, Kwiatkowski JL, Thalassemia Clinical Research Network. Pregnancy outcomes in women with thalassemia in North America and the United Kingdom. Volume 88 of Issue 9. American journal of hematology 2013. PMID: 23757266


  72. Musallam KM, Rivella S, Vichinsky E, Rachmilewitz EA. Non-transfusion-dependent thalassemias. Volume 98 of Issue 6. Haematologica 2013. PMID: 23729725


  73. Porter JB, Wood J, Olivieri N, Vichinsky EP, Taher A, Neufeld E, Giardina P, Thompson A, Moore B, Evans P, Kim HY, Macklin EA, Trachtenberg F. Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone. Volume 15 of Issue 1. Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 2013. PMID: 23688265


  74. Morris CR, Kuypers FA, Lavrisha L, Ansari M, Sweeters N, Stewart M, Gildengorin G, Neumayr L, Vichinsky EP. A randomized, placebo-controlled trial of arginine therapy for the treatment of children with sickle cell disease hospitalized with vaso-occlusive pain episodes. Volume 98 of Issue 9. Haematologica 2013. PMID: 23645695


  75. Vichinsky EP. Clinical manifestations of α-thalassemia. Volume 3 of Issue 5. Cold Spring Harbor perspectives in medicine 2013. PMID: 23543077


  76. Goldberg SL, Giardina PJ, Chirnomas D, Esposito J, Paley C, Vichinsky E. The palatability and tolerability of deferasirox taken with different beverages or foods. Volume 60 of Issue 9. Pediatric blood & cancer 2013. PMID: 23637051


  77. Morris CR, Kim HY, Wood J, Porter JB, Klings ES, Trachtenberg FL, Sweeters N, Olivieri NF, Kwiatkowski JL, Virzi L, Singer ST, Taher A, Neufeld EJ, Thompson AA, Sachdev V, Larkin S, Suh JH, Kuypers FA, Vichinsky EP, Thalassemia Clinical Research Network. Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension. Volume 98 of Issue 9. Haematologica 2013. PMID: 23585527


  78. Cui J, Azimi M, Baysdorfer C, Vichinsky EP, Hoppe CC. Application of multiplex ligation-dependent probe amplification to screen for β-globin cluster deletions: detection of two novel deletions in a multi ethnic population. Volume 37 of Issue 3. Hemoglobin 2013. PMID: 23577918


  79. Switzer WM, Shankar A, Trimble SR, Thompson AA, Giardina PJ, Cohen AR, Coates TD, Vichinsky E, Neufeld EJ, Boudreaux JM, Heneine W. Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients. Volume 29 of Issue 7. AIDS research and human retroviruses 2013. PMID: 23409829


  80. Haines D, Martin M, Carson S, Oliveros O, Green S, Coates T, Eile J, Schilling L, Dinu B, Mendoza T, Gerstenberger E, Trachtenberg F, Vichinsky E, Thalassemia Clinical Research Network. Pain in thalassaemia: the effects of age on pain frequency and severity. Volume 160 of Issue 5. British journal of haematology 2012. PMID: 23278768


  81. Walter PB, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Grady RW, Vichinsky E, Olivieri N, Trachtenberg F, Alberti D, Fung E, Ames B, Higa A, Harmatz P, Thalassemia Clinical Research Network. Increased leucocyte apoptosis in transfused ß-thalassaemia patients. British journal of haematology 2012. PMID: 23216540


  82. Lal A, Porter J, Sweeters N, Ng V, Evans P, Neumayr L, Kurio G, Harmatz P, Vichinsky E. Combined chelation therapy with deferasirox and deferoxamine in thalassemia. Blood cells, molecules & diseases 2012. PMID: 23151373


  83. Kutlar A, Ataga K, Reid M, Vichinsky EP, Neumayr L, Blair-Britt L, Labotka R, Glass J, Keefer JR, Wargin WA, Berenson R, Perrine SP. A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease. Volume 87 of Issue 11. American journal of hematology 2012. PMID: 22887019


  84. Fung EB, Gariepy CA, Sawyer AJ, Higa A, Vichinsky EP. The effect of whole body vibration therapy on bone density in patients with thalassemia: a pilot study. Volume 87 of Issue 10. American journal of hematology 2012. PMID: 22886910


  85. Fung EB, Xu Y, Trachtenberg F, Odame I, Kwiatkowski JL, Neufeld EJ, Thompson AA, Boudreaux J, Quinn CT, Vichinsky EP, Thalassemia Clinical Research Network. Inadequate dietary intake in patients with thalassemia. Volume 112 of Issue 7. Journal of the Academy of Nutrition and Dietetics 2012. PMID: 22551675


  86. Wahl SK, Garcia A, Hagar W, Gildengorin G, Quirolo K, Vichinsky E. Lower alloimmunization rates in pediatric sickle cell patients on chronic erythrocytapheresis compared to chronic simple transfusions. Volume 52 of Issue 12. Transfusion 2012. PMID: 22519830


  87. Kutlar A, Ataga KI, McMahon L, Howard J, Galacteros F, Hagar W, Vichinsky E, Cheung AT, Matsui N, Embury SH. A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease. Volume 87 of Issue 5. American journal of hematology 2012. PMID: 22488107


  88. Vichinsky E. Advances in the treatment of alpha-thalassemia. Volume 26 Suppl 1. Blood reviews 2012. PMID: 22631041


  89. Cui J, Baysdorfer C, Azimi M, Vichinsky EP, Hoppe CC. Identification of three novel Hb F variants: Hb F-Hayward [Gγ1(NA1)Gly→Asp, GGT>GAT], Hb F-Chori-I [AγT16(A13)Gly→Asp, GGC>GAC] and Hb F-Chori-II [AγI29(B11)Gly→Glu, GGA>GAA]. Volume 36 of Issue 3. Hemoglobin 2012. PMID: 22384921


  90. DeBaun MR, Armstrong FD, McKinstry RC, Ware RE, Vichinsky E, Kirkham FJ. Silent cerebral infarcts: a review on a prevalent and progressive cause of neurologic injury in sickle cell anemia. Volume 119 of Issue 20. Blood 2012. PMID: 22354000


  91. Vichinsky E.. British Journal of Haematology Safety of deferasirox in sickle cell disease patients with co-existing liver impairment – response to Sinakos et al 2012. PMID:


  92. Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ, Thalassemia Clinical Research Network. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Volume 119 of Issue 12. Blood 2012. PMID: 22279056


  93. Vichinsky E. Emerging 'A' therapies in hemoglobinopathies: agonists, antagonists, antioxidants, and arginine. Volume 2012. Hematology. American Society of Hematology. Education Program 2012. PMID: 23233591


  94. Vichinsky EP. The prevention and management of alloimmunization in sickle cell disease: the benefit of extended phenotypic matching of red blood cells. Volume 28 of Issue 1. Immunohematology 2012. PMID: 22646146


  95. Olivieri NF, Pakbaz Z, Vichinsky E. Hb E/beta-thalassaemia: a common & clinically diverse disorder. Volume 134 of Issue 4. The Indian journal of medical research 2011. PMID: 22089616


  96. Morris CR, Kim HY, Trachtenberg F, Wood J, Quinn CT, Sweeters N, Kwiatkowski JL, Thompson AA, Giardina PJ, Boudreaux J, Olivieri NF, Porter JB, Neufeld EJ, Vichinsky EP, Thalassemia Clinical Research Network. Risk factors and mortality associated with an elevated tricuspid regurgitant jet velocity measured by Doppler-echocardiography in thalassemia: a Thalassemia Clinical Research Network report. Volume 118 of Issue 14. Blood 2011. PMID: 21772051


  97. Singer ST, Vichinsky EP, Gildengorin G, van Disseldorp J, Rosen M, Cedars MI. Reproductive capacity in iron overloaded women with thalassemia major. Volume 118 of Issue 10. Blood 2011. PMID: 21757620


  98. Olivieri NF, Saunthararajah Y, Thayalasuthan V, Kwiatkowski J, Ware RE, Kuypers FA, Kim HY, Trachtenberg FL, Vichinsky EP, Thalassemia Clinical Research Network. A pilot study of subcutaneous decitabine in β-thalassemia intermedia. Volume 118 of Issue 10. Blood 2011. PMID: 21700776


  99. Vichinsky E, Bernaudin F, Forni GL, Gardner R, Hassell K, Heeney MM, Inusa B, Kutlar A, Lane P, Mathias L, Porter J, Tebbi C, Wilson F, Griffel L, Deng W, Giannone V, Coates T. Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease. Volume 154 of Issue 3. British journal of haematology 2011. PMID: 21592110


  100. Trachtenberg F, Vichinsky E, Haines D, Pakbaz Z, Mednick L, Sobota A, Kwiatkowski J, Thompson AA, Porter J, Coates T, Giardina PJ, Olivieri N, Yamashita R, Neufeld EJ, Thalassemia Clinical Research Network. Iron chelation adherence to deferoxamine and deferasirox in thalassemia. Volume 86 of Issue 5. American journal of hematology 2011. PMID: 21523808


  101. Singer ST, Vichinsky EP, Sweeters N, Rachmilewitz E. Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes. Volume 154 of Issue 2. British journal of haematology 2011. PMID: 21496003


  102. Hoppe C, Kuypers F, Larkin S, Hagar W, Vichinsky E, Styles L. A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction. Volume 153 of Issue 5. British journal of haematology 2011. PMID: 21477202


  103. Fung EB, Vichinsky EP, Kwiatkowski JL, Huang J, Bachrach LK, Sawyer AJ, Zemel BS. Characterization of low bone mass in young patients with thalassemia by DXA, pQCT and markers of bone turnover. 2011. PMID: 21443975


  104. Gold JI, Treadwell M, Weissman L, Vichinsky E. The mediating effects of family functioning on psychosocial outcomes in healthy siblings of children with sickle cell disease. 2011. PMID: 21360652


  105. Lal A, Goldrich ML, Haines DA, Azimi M, Singer ST, Vichinsky EP. Heterogeneity of hemoglobin H disease in childhood. 2011. PMID: 21345100


  106. Thompson AA, Cunningham MJ, Singer ST, Neufeld EJ, Vichinsky E, Yamashita R, Giardina P, Kim HY, Trachtenberg F, Kwiatkowski JL, Thalassemia Clinical Research Network Investigators. Red cell alloimmunization in a diverse population of transfused patients with thalassaemia. Volume 153 of Issue 1. British journal of haematology 2011. PMID: 21323889


  107. Wang, W., Brugnara, C., Snyder, C., Wynn, L., Rogers, Z., Kalinyak, K., Brown, C., Qureshi, A., Bigelow, C., Neumayr, L., Smith-Whitley, K., Chui, D. H. K., Delahunty, M., Woolson, R., Steinberg, M., Telen, M. and Kesler, K. The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial British journal of haematology 2011. PMID:


  108. Jacobs JE, Quirolo K, Vichinsky E. Novel influenza A (H1N1) viral infection in pediatric patients with sickle-cell disease. Volume 56 of Issue 1. Pediatric blood & cancer 2011. PMID: 20973097


  109. Rienhoff HY, Viprakasit V, Tay L, Harmatz P, Vichinsky E, Chirnomas D, Kwiatkowski JL, Tapper A, Kramer W, Porter JB, Neufeld EJ. A phase 1 dose-escalation study: safety, tolerability, and pharmacokinetics of FBS0701, a novel oral iron chelator for the treatment of transfusional iron overload. Haematologica 2010. PMID: 21173101


  110. Olivieri NF, Pakbaz Z, Vichinsky E. HbE/β-thalassemia: basis of marked clinical diversity. Volume 24 of Issue 6. Hematology/oncology clinics of North America 2010. PMID: 21075280


  111. Neumayr L, Pringle S, Giles S, Quirolo KC, Paulukonis S, Vichinsky EP, Treadwell MJ. Chart Card: feasibility of a tool for improving emergency department care in sickle cell disease. 2010. PMID: 21141289


  112. Pakbaz Z, Treadwell M, Kim HY, Trachtenberg F, Parmar N, Kwiatkowski JL, Cunningham MJ, Martin M, Sweeters N, Neufeld EJ, Giardina PJ, Olivieri N, Yamashita RC, Vichinsky E. Education and employment status of children and adults with thalassemia in North America. 2010. PMID: 20535817


  113. Gladwin MT, Barst RJ, Castro OL, Gordeuk VR, Hillery CA, Kato GJ, Kim-Shapiro DB, Machado R, Morris CR, Steinberg MH, Vichinsky EP. Pulmonary hypertension and NO in sickle cell. Volume 116 of Issue 5. Blood 2010. PMID: 20688967


  114. Vichinsky E. Complexity of alpha thalassemia: growing health problem with new approaches to screening, diagnosis, and therapy. Volume 1202. Annals of the New York Academy of Sciences 2010. PMID: 20712791


  115. Singer ST, Sweeters N, Vega O, Higa A, Vichinsky E, Cedars M. Fertility potential in thalassemia major women: current findings and future diagnostic tools. Volume 1202. Annals of the New York Academy of Sciences 2010. PMID: 20712797


  116. Vichinsky EP, Neufeld EJ. Preface to Cooley's Anemia: Ninth Symposium. Volume 1202. Annals of the New York Academy of Sciences 2010. PMID: 20712763


  117. Morris CR, Vichinsky EP. Pulmonary hypertension in thalassemia. Volume 1202. Annals of the New York Academy of Sciences 2010. PMID: 20712794


  118. Vichinsky EP, Ohene-Frempong K, Transfusion Committee. Approaches to transfusion therapy and iron overload in patients with sickle cell disease: results of an international survey. Volume 28 of Issue 1. Pediatric hematology and oncology 2010. PMID: 20673029


  119. Vichinsky EP, Ohene-Frempong K, Thein SL, Lobo CL, Inati A, Thompson AA, Smith-Whitley K, Kwiatkowski JL, Swerdlow PS, Porter JB, Marks PW. Transfusion and chelation practices in sickle cell disease: a regional perspective. Volume 28 of Issue 2. Pediatric hematology and oncology 2010. PMID: 20673030


  120. Fung EB, Xu Y, Kwiatkowski JL, Vogiatzi MG, Neufeld E, Olivieri N, Vichinsky EP, Giardina PJ, Thalassemia Clinical Research Network. Relationship between chronic transfusion therapy and body composition in subjects with thalassemia. Volume 157 of Issue 4. The Journal of pediatrics 2010. PMID: 20547400


  121. Vichinsky EP, Neumayr LD, Gold JI, Weiner MW, Rule RR, Truran D, Kasten J, Eggleston B, Kesler K, McMahon L, Orringer EP, Harrington T, Kalinyak K, De Castro LM, Kutlar A, Rutherford CJ, Johnson C, Bessman JD, Jordan LB, Armstrong FD, Neuropsychological Dysfunction and Neuroimaging Adult Sickle Cell Anemia Study Group. Neuropsychological dysfunction and neuroimaging abnormalities in neurologically intact adults with sickle cell anemia. Volume 303 of Issue 18. JAMA 2010. PMID: 20460621


  122. James EB, Vreman HJ, Wong RJ, Stevenson DK, Vichinsky E, Schumacher L, Hall JY, Simon J, Golden DW, Harmatz P. Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy. Pediatric hematology and oncology 2010. PMID: 20201692


  123. Wahl S, Vichinsky E. Pulmonary hypertension in hemolytic anemias. Volume 2. F1000 medicine reports 2010. PMID: 20948876


  124. Kanathezhath B, Hazard FK, Guo H, Kidd J, Azimi M, Kuypers FA, Vichinsky EP, Lal A. Hemoglobin Hakkari: an autosomal dominant form of beta thalassemia with inclusion bodies arising from de novo mutation in exon 2 of beta globin gene. Volume 54 of Issue 2. Pediatric blood & cancer 2010. PMID: 19852066


  125. Wang ZJ, Fischer R, Chu Z, Mahoney DH, Mueller BU, Muthupillai R, James EB, Krishnamurthy R, Chung T, Padua E, Vichinsky E, Harmatz P. Assessment of cardiac iron by MRI susceptometry and R2* in patients with thalassemia. Magnetic resonance imaging 2010. PMID: 20061110


  126. Gabrovsky A, Aderinto A, Aderinto A, Spevak M, Vichinsky E, Resar LM. Low dose, oral epsilon aminocaproic acid for renal papillary necrosis and massive hemorrhage in hemoglobin SC disease. Volume 54 of Issue 1. Pediatric blood & cancer 2010. PMID: 19785026


  127. Kidd JL, Azimi M, Lubin B, Vichinsky E, Hoppe C. Application of an expanded multiplex genotyping assay for the simultaneous detection of Hemoglobin Constant Spring and common deletional alpha-thalassemia mutations. Volume 32 of Issue 4. International journal of laboratory hematology 2009. PMID: 19919622


  128. Walter PB, Harmatz P, Vichinsky E. Iron metabolism and iron chelation in sickle cell disease. Acta haematologica 2009. PMID: 19907155


  129. Singer ST, Kim HY, Olivieri NF, Kwiatkowski JL, Coates TD, Carson S, Neufeld E, Cunningham MJ, Giardina PJ, Mueller BU, Quinn CT, Fung E, Vichinsky E, Thalassemia Clinical Research Network. Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications. Volume 84 of Issue 11. American journal of hematology 2009. PMID: 19787795


  130. Buchanan G, Vichinsky E, Krishnamurti L, Shenoy S. Severe sickle cell disease--pathophysiology and therapy. Volume 16 of Issue 1 Suppl. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2009. PMID: 19819341


  131. Taher A, Cappellini MD, Vichinsky E, Galanello R, Piga A, Lawniczek T, Clark J, Habr D, Porter JB. Efficacy and safety of deferasirox doses of >30 mg/kg per d in patients with transfusion-dependent anaemia and iron overload. Volume 147 of Issue 5. British journal of haematology 2009. PMID: 19764988


  132. Adamkiewicz TV, Abboud MR, Paley C, Olivieri N, Kirby-Allen M, Vichinsky E, Casella JF, Alvarez OA, Barredo JC, Lee MT, Iyer RV, Kutlar A, McKie KM, McKie V, Odo N, Gee B, Kwiatkowski JL, Woods GM, Coates T, Wang W, Adams RJ. Serum ferritin level changes in children with sickle cell disease on chronic blood transfusion are nonlinear and are associated with iron load and liver injury. Volume 114 of Issue 21. Blood 2009. PMID: 19721013


  133. Vogiatzi MG, Macklin EA, Trachtenberg FL, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Fleisher M, Grady RW, Peterson CM, Giardina PJ, Thalassemia Clinical Research Network. Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America. Volume 146 of Issue 5. British journal of haematology 2009. PMID: 19604241


  134. Hoppe C, Klitz W, Vichinsky E, Styles L. HLA type and risk of alloimmunization in sickle cell disease. Volume 84 of Issue 7. American journal of hematology 2009. PMID: 19484735


  135. Michlitsch J, Azimi M, Hoppe C, Walters MC, Lubin B, Lorey F, Vichinsky E. Newborn screening for hemoglobinopathies in California. 2009. PMID: 19061217


  136. Vogiatzi MG, Macklin EA, Fung EB, Cheung AM, Vichinsky E, Olivieri N, Kirby M, Kwiatkowski JL, Cunningham M, Holm IA, Lane J, Schneider R, Fleisher M, Grady RW, Peterson CC, Giardina PJ, Thalassemia Clinical Research Network. Bone disease in thalassemia: a frequent and still unresolved problem. Volume 24 of Issue 3. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2009. PMID: 18505376


  137. Vichinsky EP. Alpha thalassemia major--new mutations, intrauterine management, and outcomes. Hematology. American Society of Hematology. Education Program 2009. PMID: 20008180


  138. Gladwin MT, Vichinsky E. Pulmonary complications of sickle cell disease. Volume 359 of Issue 21. The New England journal of medicine 2008. PMID: 19020327


  139. Vichinsky E, Rodgers GP, Rachmilewitz E. Hemoglobinopathies. Volume 8 of Issue 7. Current molecular medicine 2008. PMID: 18991644


  140. Singer ST, Vichinsky EP, Larkin S, Olivieri N, Sweeters N, Kuypers FA, E/beta Thalassemia Study Group. Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells. Volume 83 of Issue 11. American journal of hematology 2008. PMID: 18821710


  141. Gold JI, Mahrer NE, Treadwell M, Weissman L, Vichinsky E. Psychosocial and behavioral outcomes in children with sickle cell disease and their healthy siblings. 2008. PMID: 18784995


  142. Harmatz P, Jonas MM, Kwiatkowski JL, Wright EC, Fischer R, Vichinsky E, Giardina PJ, Neufeld EJ, Porter J, Olivieri N, Thalassemia Clinical Research Network. Safety and efficacy of pegylated interferon alpha-2a and ribavirin for the treatment of hepatitis C in patients with thalassemia. Haematologica 2008. PMID: 18556414


  143. Gold JI, Johnson CB, Treadwell MJ, Hans N, Vichinsky E. Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging. 2008. PMID: 18569843


  144. Vichinsky E. Oral iron chelators and the treatment of iron overload in pediatric patients with chronic anemia. Volume 121 of Issue 6. Pediatrics 2008. PMID: 18519495


  145. Fung EB, Harmatz PR, Milet M, Balasa V, Ballas SK, Casella JF, Hilliard L, Kutlar A, McClain KL, Olivieri NF, Porter JB, Vichinsky EP, Multi-Center Iron Overload Research Group. Disparity in the management of iron overload between patients with sickle cell disease and thalassemia who received transfusions. Transfusion 2008. PMID: 18513257


  146. Gold JI, Treadwell M, Weissman L, Vichinsky E. An expanded Transactional Stress and Coping Model for siblings of children with sickle cell disease: family functioning and sibling coping, self-efficacy and perceived social support. 2008. PMID: 18485027


  147. Walter PB, Macklin EA, Porter J, Evans P, Kwiatkowski JL, Neufeld EJ, Coates T, Giardina PJ, Vichinsky E, Olivieri N, Alberti D, Holland J, Harmatz P, Thalassemia Clinical Research Network. Inflammation and oxidant-stress in beta-thalassemia patients treated with iron chelators deferasirox (ICL670) or deferoxamine: an ancillary study of the Novartis CICL670A0107 trial. Haematologica 2008. PMID: 18469351


  148. Vichinsky E. Clinical application of deferasirox: practical patient management. Volume 83 of Issue 5. American journal of hematology 2008. PMID: 18058997


  149. Vichinsky E, Pakbaz Z, Onyekwere O, Porter J, Swerdlow P, Coates T, Lane P, Files B, Mueller BU, Coïc L, Forni GL, Fischer R, Marks P, Rofail D, Abetz L, Baladi JF. Patient-reported outcomes of deferasirox (Exjade, ICL670) versus deferoxamine in sickle cell disease patients with transfusional hemosiderosis. Substudy of a randomized open-label phase II trial. Volume 119 of Issue 3. Acta haematologica 2008. PMID: 18408362


  150. Fung EB, Harmatz PR, Milet M, Coates TD, Thompson AA, Ranalli M, Mignaca R, Scher C, Giardina P, Robertson S, Neumayr L, Vichinsky EP, Multi-Center Iron Overload Study Group. Fracture prevalence and relationship to endocrinopathy in iron overloaded patients with sickle cell disease and thalassemia. Bone 2008. PMID: 18430624


  151. Hagar W, Vichinsky E. Advances in clinical research in sickle cell disease. Volume 141 of Issue 3. British journal of haematology 2008. PMID: 18341629


  152. Jastaniah W, Harmatz P, Pakbaz Z, Fischer R, Vichinsky E, Walters MC. Transfusional iron burden and liver toxicity after bone marrow transplantation for acute myelogenous leukemia and hemoglobinopathies. Pediatric blood & cancer 2008. PMID: 17557314


  153. Ataga KI, Smith WR, De Castro LM, Swerdlow P, Saunthararajah Y, Castro O, Vichinsky E, Kutlar A, Orringer EP, Rigdon GC, Stocker JW, ICA-17043-05 Investigators. Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia. Volume 111 of Issue 8. Blood 2008. PMID: 18192510


  154. Porter JB, Taher AT, Cappellini MD, Vichinsky EP. Ethical issues and risk/benefit assessment of iron chelation therapy: advances with deferiprone/deferoxamine combinations and concerns about the safety, efficacy and costs of deferasirox [Kontoghiorghes GJ, Hemoglobin 2008; 32(1-2):1-15.]. Volume 32 of Issue 6. Hemoglobin 2008. PMID: 19065340


  155. Porter J, Galanello R, Saglio G, Neufeld EJ, Vichinsky E, Cappellini MD, Olivieri N, Piga A, Cunningham MJ, Soulières D, Gattermann N, Tchernia G, Maertens J, Giardina P, Kwiatkowski J, Quarta G, Jeng M, Forni GL, Stadler M, Cario H, Debusscher L, Della Porta M, Cazzola M, Greenberg P, Alimena G, Rabault B, Gathmann I, Ford JM, Alberti D, Rose C. Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study. Volume 80 of Issue 2. European journal of haematology 2007. PMID: 18028431


  156. Hagar RW, Michlitsch JG, Gardner J, Vichinsky EP, Morris CR. Clinical differences between children and adults with pulmonary hypertension and sickle cell disease. 2007. PMID: 17916102


  157. Morris CR, Suh JH, Hagar W, Larkin S, Bland DA, Steinberg MH, Vichinsky EP, Shigenaga M, Ames B, Kuypers FA, Klings ES. Erythrocyte glutamine depletion, altered redox environment, and pulmonary hypertension in sickle cell disease. Volume 111 of Issue 1. Blood 2007. PMID: 17848621


  158. Pakbaz Z, Fischer R, Fung E, Nielsen P, Harmatz P, Vichinsky E. Serum ferritin underestimates liver iron concentration in transfusion independent thalassemia patients as compared to regularly transfused thalassemia and sickle cell patients. Pediatric blood & cancer 2007. PMID: 17554789


  159. Harmatz P, Grady RW, Dragsten P, Vichinsky E, Giardina P, Madden J, Jeng M, Miller B, Hanson G, Hedlund B. Phase Ib clinical trial of starch-conjugated deferoxamine (40SD02): a novel long-acting iron chelator. British journal of haematology 2007. PMID: 17614825


  160. Jenkins ZA, Hagar W, Bowlus CL, Johansson HE, Harmatz P, Vichinsky EP, Theil EC. Iron homeostasis during transfusional iron overload in beta-thalassemia and sickle cell disease: changes in iron regulatory protein, hepcidin, and ferritin expression. Pediatric hematology and oncology 2007. PMID: 17613866


  161. Cappellini MD, Bejaoui M, Agaoglu L, Porter J, Coates T, Jeng M, Lai ME, Mangiagli A, Strauss G, Girot R, Watman N, Ferster A, Loggetto S, Abish S, Cario H, Zoumbos N, Vichinsky E, Opitz H, Ressayre-Djaffer C, Abetz L, Rofail D, Baladi JF. Prospective evaluation of patient-reported outcomes during treatment with deferasirox or deferoxamine for iron overload in patients with beta-thalassemia. Volume 29 of Issue 5. Clinical therapeutics 2007. PMID: 17697909


  162. Fung EB, Harmatz P, Milet M, Ballas SK, De Castro L, Hagar W, Owen W, Olivieri N, Smith-Whitley K, Darbari D, Wang W, Vichinsky E, Multi-Center Study of Iron Overload Research Group. Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload. American journal of hematology 2007. PMID: 17094096


  163. Vichinsky E, Onyekwere O, Porter J, Swerdlow P, Eckman J, Lane P, Files B, Hassell K, Kelly P, Wilson F, Bernaudin F, Forni GL, Okpala I, Ressayre-Djaffer C, Alberti D, Holland J, Marks P, Fung E, Fischer R, Mueller BU, Coates T, Deferasirox in Sickle Cell Investigators. A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Volume 136 of Issue 3. British journal of haematology 2007. PMID: 17233848


  164. Moskowitz JT, Butensky E, Harmatz P, Vichinsky E, Heyman MB, Acree M, Wrubel J, Wilson L, Folkman S. Caregiving time in sickle cell disease: psychological effects in maternal caregivers. Pediatric blood & cancer 2007. PMID: 16622841


  165. Vichinsky E. Hemoglobin e syndromes. Hematology. American Society of Hematology. Education Program 2007. PMID: 18024613


  166. Lal A, Fung EB, Pakbaz Z, Hackney-Stephens E, Vichinsky EP. Bone mineral density in children with sickle cell anemia. 2006. PMID: 16317761


  167. Neumayr LD, Aguilar C, Earles AN, Jergesen HE, Haberkern CM, Kammen BF, Nancarrow PA, Padua E, Milet M, Stulberg BN, Williams RA, Orringer EP, Graber N, Robertson SM, Vichinsky EP, National Osteonecrosis Trial in Sickle Cell Anemia Study Group. Physical therapy alone compared with core decompression and physical therapy for femoral head osteonecrosis in sickle cell disease. Results of a multicenter study at a mean of three years after treatment. Volume 88 of Issue 12. The Journal of bone and joint surgery. American volume 2006. PMID: 17142406


  168. Ataga KI, Orringer EP, Styles L, Vichinsky EP, Swerdlow P, Davis GA, Desimone PA, Stocker JW. Dose-escalation study of ICA-17043 in patients with sickle cell disease. Volume 26 of Issue 11. Pharmacotherapy 2006. PMID: 17064199


  169. Fung EB, Harmatz PR, Lee PD, Milet M, Bellevue R, Jeng MR, Kalinyak KA, Hudes M, Bhatia S, Vichinsky EP, Multi-Centre Study of Iron Overload Research Group. Increased prevalence of iron-overload associated endocrinopathy in thalassaemia versus sickle-cell disease. British journal of haematology 2006. PMID: 17054676


  170. Walter PB, Fung EB, Killilea DW, Jiang Q, Hudes M, Madden J, Porter J, Evans P, Vichinsky E, Harmatz P. Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease. British journal of haematology 2006. PMID: 17010049


  171. Hoppe C, Watson RM, Long CM, Lorey F, Robles L, Klitz W, Styles L, Vichinsky E. Prevalence of HFE mutations in California newborns. Volume 23 of Issue 6. Pediatric hematology and oncology 2006. PMID: 16849282


  172. Singer ST, Kuypers FA, Styles L, Vichinsky EP, Foote D, Rosenfeld H. Pulmonary hypertension in thalassemia: association with platelet activation and hypercoagulable state. Volume 81 of Issue 9. American journal of hematology 2006. PMID: 16795058


  173. Hagar RW, Morris CR, Vichinsky EP. Pulmonary hypertension in thalassaemia major patients with normal left ventricular systolic function. Volume 133 of Issue 4. British journal of haematology 2006. PMID: 16643452


  174. Treadwell MJ, McClough L, Vichinsky E. Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait. 2006. PMID: 16749645


  175. Vogiatzi MG, Macklin EA, Fung EB, Vichinsky E, Olivieri N, Kwiatkowski J, Cohen A, Neufeld E, Giardina PJ. Prevalence of fractures among the Thalassemia syndromes in North America. Volume 38 of Issue 4. Bone 2005. PMID: 16298178


  176. Vichinsky EP, MacKlin EA, Waye JS, Lorey F, Olivieri NF. Changes in the epidemiology of thalassemia in North America: a new minority disease. Volume 116 of Issue 6. Pediatrics 2005. PMID: 16291734


  177. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP, E/beta Thalassaemia Study Group. Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome. Volume 131 of Issue 3. British journal of haematology 2005. PMID: 16225658


  178. Aguilar C, Vichinsky E, Neumayr L. Bone and joint disease in sickle cell disease. Volume 19 of Issue 5. Hematology/oncology clinics of North America 2005. PMID: 16214653


  179. Vichinsky E, Butensky E, Fung E, Hudes M, Theil E, Ferrell L, Williams R, Louie L, Lee PD, Harmatz P. Comparison of organ dysfunction in transfused patients with SCD or beta thalassemia. American journal of hematology 2005. PMID: 16138345


  180. Morris CR, Kato GJ, Poljakovic M, Wang X, Blackwelder WC, Sachdev V, Hazen SL, Vichinsky EP, Morris SM, Gladwin MT. Dysregulated arginine metabolism, hemolysis-associated pulmonary hypertension, and mortality in sickle cell disease. Volume 294 of Issue 1. JAMA 2005. PMID: 15998894


  181. Aguilar CM, Neumayr LD, Eggleston BE, Earles AN, Robertson SM, Jergesen HE, Stulberg BN, Vichinsky EP. Clinical evaluation of avascular necrosis in patients with sickle cell disease: Children's Hospital Oakland Hip Evaluation Scale--a modification of the Harris Hip Score. Volume 86 of Issue 7. Archives of physical medicine and rehabilitation 2005. PMID: 16003666


  182. Treadwell MJ, Law AW, Sung J, Hackney-Stephens E, Quirolo K, Murray E, Glendenning GA, Vichinsky E. Barriers to adherence of deferoxamine usage in sickle cell disease. 2005. PMID: 15602707


  183. Pakbaz Z, Fischer R, Treadwell M, Yamashita R, Fung EB, Calvelli L, Quirolo K, Foote D, Harmatz P, Vichinsky EP. A simple model to assess and improve adherence to iron chelation therapy with deferoxamine in patients with thalassemia. Annals of the New York Academy of Sciences 2005. PMID: 16339703


  184. Vichinsky EP. Changing patterns of thalassemia worldwide. Volume 1054. Annals of the New York Academy of Sciences 2005. PMID: 16339647


  185. Premawardhena A, De Silver S, Arambepola M, Olivieri NF, Vichinsky EP, Merson L, Muraco G, Allen A, Fisher C, Peto T, Weatherall DJ. Hemoglobin E-beta-thalassemia: Progress report from the International Study Group. Volume 1054. Annals of the New York Academy of Sciences 2005. PMID: 16339649


  186. Morris CR, Kuypers FA, Kato GJ, Lavrisha L, Larkin S, Singer T, Vichinsky EP. Hemolysis-associated pulmonary hypertension in thalassemia. Volume 1054. Annals of the New York Academy of Sciences 2005. PMID: 16339702


  187. Offer T, Bhagat A, Lal A, Atamna W, Singer ST, Vichinsky EP, Kuypers FA, Ames BN. Measuring chromosome breaks in patients with thalassemia. 2005. PMID: 16339694


  188. Qureshi N, Foote D, Walters MC, Singer ST, Quirolo K, Vichinsky EP. Outcomes of preimplantation genetic diagnosis therapy in treatment of beta-thalassemia: A retrospective analysis. Volume 1054. Annals of the New York Academy of Sciences 2005. PMID: 16339706


  189. Pakbaz Z, Treadwell M, Yamashita R, Quirolo K, Foote D, Quill L, Singer T, Vichinsky EP. Quality of life in patients with thalassemia intermedia compared to thalassemia major. 2005. PMID: 16339697


  190. Singer ST, Kuypers FA, Olivieri NF, Weatherall DJ, Mignacca R, Coates TD, Davies S, Sweeters N, Vichinsky EP. Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment. Volume 1054. Annals of the New York Academy of Sciences 2005. PMID: 16339672


  191. Butensky E, Pakbaz Z, Foote D, Walters MC, Vichinsky EP, Harmatz P. Treatment of hepatitis C virus infection in thalassemia. Annals of the New York Academy of Sciences 2005. PMID: 16339677


  192. Qureshi N, Avasarala K, Foote D, Vichinsky EP. Utility of Holter electrocardiogram in iron-overloaded hemoglobinopathies. Annals of the New York Academy of Sciences 2005. PMID: 16339701


  193. Butensky E, Fischer R, Hudes M, Schumacher L, Williams R, Moyer TP, Vichinsky E, Harmatz P. Variability in hepatic iron concentration in percutaneous needle biopsy specimens from patients with transfusional hemosiderosis. American journal of clinical pathology 2005. PMID: 15762291


  194. Jeng MR, Vichinsky E. Hematologic problems in immigrants from Southeast Asia. Volume 18 of Issue 6. Hematology/oncology clinics of North America 2004. PMID: 15511622


  195. Fung EB, Fischer R, Pakbaz Z, Fagaly RL, Vichinsky E, Starr TN, Ewing T, Paulson DN, Hassenzahl WV, Harmatz P. The new SQUID biosusceptometer at Oakland: first year of experience. Neurology & clinical neurophysiology : NCN 2004. PMID: 16012600


  196. Jones A, Granger S, Brambilla D, Gallagher D, Vichinsky E, Woods G, Berman B, Roach S, Nichols F, Adams RJ. Can peak systolic velocities be used for prediction of stroke in sickle cell anemia? Volume 35 of Issue 1. Pediatric radiology 2004. PMID: 15517239


  197. Premawardhena A, De Silva S, Arambepola M, Olivieri N, Merson L, Muraco J, Allen A, Fisher C, Peto T, Vichinsky E, Weatherall D. Thalassemia in Sri Lanka: a progress report. Volume 13 Spec No 2. Human molecular genetics 2004. PMID: 15358726


  198. Lal A, Vichinsky E. The role of fetal hemoglobin-enhancing agents in thalassemia. 2004. PMID: 15534853


  199. Vichinsky EP. Pulmonary hypertension in sickle cell disease. Volume 350 of Issue 9. The New England journal of medicine 2004. PMID: 14985481


  200. Adams RJ, Brambilla DJ, Granger S, Gallagher D, Vichinsky E, Abboud MR, Pegelow CH, Woods G, Rohde EM, Nichols FT, Jones A, Luden JP, Bowman L, Hagner S, Morales KH, Roach ES, STOP Study. Stroke and conversion to high risk in children screened with transcranial Doppler ultrasound during the STOP study. Volume 103 of Issue 10. Blood 2004. PMID: 14751925


  201. Cohen AR, Galanello R, Pennell DJ, Cunningham MJ, Vichinsky E. Thalassemia. Hematology. American Society of Hematology. Education Program 2004. PMID: 15561674


  202. Claster S, Vichinsky EP. Managing sickle cell disease. Volume 327 of Issue 7424. BMJ (Clinical research ed.) 2003. PMID: 14615343


  203. Hoppe C, Klitz W, Cheng S, Apple R, Steiner L, Robles L, Girard T, Vichinsky E, Styles L, CSSCD Investigators. Gene interactions and stroke risk in children with sickle cell anemia. Volume 103 of Issue 6. Blood 2003. PMID: 14615367


  204. Adamkiewicz TV, Sarnaik S, Buchanan GR, Iyer RV, Miller ST, Pegelow CH, Rogers ZR, Vichinsky E, Elliott J, Facklam RR, O'Brien KL, Schwartz B, Van Beneden CA, Cannon MJ, Eckman JR, Keyserling H, Sullivan K, Wong WY, Wang WC. Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysaccharide vaccination. Volume 143 of Issue 4. The Journal of pediatrics 2003. PMID: 14571216


  205. Morris CR, Vichinsky EP, van Warmerdam J, Machado L, Kepka-Lenhart D, Morris SM, Kuypers FA. Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease. Volume 25 of Issue 8. Journal of pediatric hematology/oncology 2003. PMID: 12902916


  206. Neumayr L, Lennette E, Kelly D, Earles A, Embury S, Groncy P, Grossi M, Grover R, McMahon L, Swerdlow P, Waldron P, Vichinsky E. Mycoplasma disease and acute chest syndrome in sickle cell disease. Volume 112 of Issue 1 Pt 1. Pediatrics 2003. PMID: 12837872


  207. Brittenham GM, Nathan DG, Olivieri NF, Porter JB, Pippard M, Vichinsky EP, Weatherall DJ. Deferiprone and hepatic fibrosis. Volume 101 of Issue 12. Blood 2003. PMID: 12788794


  208. Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, Orringer E, Bellevue R, Olivieri N, Eckman J, Varma M, Ramirez G, Adler B, Smith W, Carlos T, Ataga K, DeCastro L, Bigelow C, Saunthararajah Y, Telfer M, Vichinsky E, Claster S, Shurin S, Bridges K, Waclawiw M, Bonds D, Terrin M. Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment. Volume 289 of Issue 13. JAMA 2003. PMID: 12672732


  209. Hagar W, Vichinsky EP, Theil EC. Liver ferritin subunit ratios in neonatal hemochromatosis. Volume 20 of Issue 3. Pediatric hematology and oncology 2003. PMID: 12637219


  210. Morris CR, Morris SM, Hagar W, Van Warmerdam J, Claster S, Kepka-Lenhart D, Machado L, Kuypers FA, Vichinsky EP. Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease? Volume 168 of Issue 1. American journal of respiratory and critical care medicine 2003. PMID: 12626350


  211. Dean D, Neumayr L, Kelly DM, Ballas SK, Kleman K, Robertson S, Iyer RV, Ware RE, Koshy M, Rackoff WR, Pegelow CH, Waldron P, Benjamin L, Vichinsky E, Acute Chest Syndrome Study Group. Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease. Journal of pediatric hematology/oncology 2003. PMID: 12544773


  212. Hoppe C, Klitz W, Noble J, Vigil L, Vichinsky E, Styles L. Distinct HLA associations by stroke subtype in children with sickle cell anemia. Volume 101 of Issue 7. Blood 2002. PMID: 12517810


  213. Pegelow CH, Macklin EA, Moser FG, Wang WC, Bello JA, Miller ST, Vichinsky EP, DeBaun MR, Guarini L, Zimmerman RA, Younkin DP, Gallagher DM, Kinney TR. Longitudinal changes in brain magnetic resonance imaging findings in children with sickle cell disease. Volume 99 of Issue 8. Blood 2002. PMID: 11929794


  214. Franck LS, Treadwell M, Jacob E, Vichinsky E. Assessment of sickle cell pain in children and young adults using the adolescent pediatric pain tool. 2002. PMID: 11844631


  215. Wang WC, Helms RW, Lynn HS, Redding-Lallinger R, Gee BE, Ohene-Frempong K, Smith-Whitley K, Waclawiw MA, Vichinsky EP, Styles LA, Ware RE, Kinney TR. Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study. Volume 140 of Issue 2. The Journal of pediatrics 2002. PMID: 11865275


  216. Treadwell MJ, Franck LS, Vichinsky E. Using quality improvement strategies to enhance pediatric pain assessment. 2002. PMID: 11871628


  217. Pegelow CH, Wang W, Granger S, Hsu LL, Vichinsky E, Moser FG, Bello J, Zimmerman RA, Adams RJ, Brambilla D, STOP Trial. Silent infarcts in children with sickle cell anemia and abnormal cerebral artery velocity. Volume 58 of Issue 12. Archives of neurology 2001. PMID: 11735775


  218. Hoppe C, Cheng S, Grow M, Silbergleit A, Klitz W, Trachtenberg E, Erlich H, Vichinsky E, Styles L. A novel multilocus genotyping assay to identify genetic predictors of stroke in sickle cell anaemia. Volume 114 of Issue 3. British journal of haematology 2001. PMID: 11553004


  219. Wang W, Enos L, Gallagher D, Thompson R, Guarini L, Vichinsky E, Wright E, Zimmerman R, Armstrong FD, Cooperative Study of Sickle Cell Disease. Neuropsychologic performance in school-aged children with sickle cell disease: a report from the Cooperative Study of Sickle Cell Disease. Volume 139 of Issue 3. The Journal of pediatrics 2001. PMID: 11562619


  220. Vichinsky EP, Luban NL, Wright E, Olivieri N, Driscoll C, Pegelow CH, Adams RJ, Stroke Prevention Trail in Sickle Cell Anemia. Prospective RBC phenotype matching in a stroke-prevention trial in sickle cell anemia: a multicenter transfusion trial. Volume 41 of Issue 9. Transfusion 2001. PMID: 11552063


  221. Miller ST, Macklin EA, Pegelow CH, Kinney TR, Sleeper LA, Bello JA, DeWitt LD, Gallagher DM, Guarini L, Moser FG, Ohene-Frempong K, Sanchez N, Vichinsky EP, Wang WC, Wethers DL, Younkin DP, Zimmerman RA, DeBaun MR, Cooperative Study of Sickle Cell Disease. Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease. Volume 139 of Issue 3. The Journal of pediatrics 2001. PMID: 11562618


  222. Cheung AT, Harmatz P, Wun T, Chen PC, Larkin EC, Adams RJ, Vichinsky EP. Correlation of abnormal intracranial vessel velocity, measured by transcranial Doppler ultrasonography, with abnormal conjunctival vessel velocity, measured by computer-assisted intravital microscopy, in sickle cell disease. Blood 2001. PMID: 11369629


  223. Culberson DE, Manci EA, Shah AK, Haynes J, Ballas SK, Pegelow C, Vichinsky E. Nesidioblastosis in sickle cell disease. Volume 20 of Issue 2. Pediatric pathology & molecular medicine 2001. PMID: 12673839


  224. Walters MC, Patience M, Leisenring W, Rogers ZR, Aquino VM, Buchanan GR, Roberts IA, Yeager AM, Hsu L, Adamkiewicz T, Kurtzberg J, Vichinsky E, Storer B, Storb R, Sullivan KM, Multicenter Investigation of Bone Marrow Transplantation for Sickle Cell Disease. Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia. Volume 7 of Issue 12. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2001. PMID: 11787529


  225. Fixler J, Vichinsky E, Walters MC. Stem cell transplantation for sickle cell disease: can we reduce the toxicity? Volume 20 of Issue 1. Pediatric pathology & molecular medicine 2001. PMID: 12673845


  226. Lorey F, Cunningham G, Vichinsky EP, Lubin BH, Witkowska HE, Matsunaga A, Azimi M, Sherwin J, Eastman J, Farina F, Waye JS, Chui DH. Universal newborn screening for Hb H disease in California. Volume 5 of Issue 2. Genetic testing 2001. PMID: 11551109


  227. Singer ST, Wu V, Mignacca R, Kuypers FA, Morel P, Vichinsky EP. Alloimmunization and erythrocyte autoimmunization in transfusion-dependent thalassemia patients of predominantly asian descent. Volume 96 of Issue 10. Blood 2000. PMID: 11071629


  228. Morris CR, Kuypers FA, Larkin S, Sweeters N, Simon J, Vichinsky EP, Styles LA. Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease. Volume 111 of Issue 2. British journal of haematology 2000. PMID: 11122090


  229. Singer ST, Styles L, Bojanowski J, Quirolo K, Foote D, Vichinsky EP. Changing outcome of homozygous alpha-thalassemia: cautious optimism. Volume 22 of Issue 6. Journal of pediatric hematology/oncology 2000. PMID: 11132224


  230. Choy J, Foote D, Bojanowski J, Yamashita R, Vichinsky E. Outreach strategies for Southeast Asian communities: experience, practice, and suggestions for approaching Southeast Asian immigrant and refugee communities to provide thalassemia education and trait testing. Volume 22 of Issue 6. Journal of pediatric hematology/oncology 2000. PMID: 11132235


  231. Morris CR, Kuypers FA, Larkin S, Vichinsky EP, Styles LA. Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome. Volume 22 of Issue 6. Journal of pediatric hematology/oncology 2000. PMID: 11132219


  232. Styles LA, Aarsman AJ, Vichinsky EP, Kuypers FA. Secretory phospholipase A(2) predicts impending acute chest syndrome in sickle cell disease. Volume 96 of Issue 9. Blood 2000. PMID: 11050014


  233. Wang WC, Gallagher DM, Pegelow CH, Wright EC, Vichinsky EP, Abboud MR, Moser FG, Adams RJ. Multicenter comparison of magnetic resonance imaging and transcranial Doppler ultrasonography in the evaluation of the central nervous system in children with sickle cell disease. Volume 22 of Issue 4. Journal of pediatric hematology/oncology 2000. PMID: 10959904


  234. Harmatz P, Butensky E, Quirolo K, Williams R, Ferrell L, Moyer T, Golden D, Neumayr L, Vichinsky E. Severity of iron overload in patients with sickle cell disease receiving chronic red blood cell transfusion therapy. Blood 2000. PMID: 10891433


  235. Hoppe C, Vichinsky E, Quirolo K, van Warmerdam J, Allen K, Styles L. Use of hydroxyurea in children ages 2 to 5 years with sickle cell disease. Volume 22 of Issue 4. Journal of pediatric hematology/oncology 2000. PMID: 10959903


  236. Vichinsky EP, Neumayr LD, Earles AN, Williams R, Lennette ET, Dean D, Nickerson B, Orringer E, McKie V, Bellevue R, Daeschner C, Manci EA. Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group. Volume 342 of Issue 25. The New England journal of medicine 2000. PMID: 10861320


  237. Styles LA, Hoppe C, Klitz W, Vichinsky E, Lubin B, Trachtenberg E. Evidence for HLA-related susceptibility for stroke in children with sickle cell disease. Volume 95 of Issue 11. Blood 2000. PMID: 10828044


  238. Walters MC, Storb R, Patience M, Leisenring W, Taylor T, Sanders JE, Buchanan GE, Rogers ZR, Dinndorf P, Davies SC, Roberts IA, Dickerhoff R, Yeager AM, Hsu L, Kurtzberg J, Ohene-Frempong K, Bunin N, Bernaudin F, Wong WY, Scott JP, Margolis D, Vichinsky E, Wall DA, Wayne AS, Pegelow C, Redding-Lallinger R, Wiley J, Klemperer M, Mentzer WC, Smith FO, Sullivan KM. Impact of bone marrow transplantation for symptomatic sickle cell disease: an interim report. Multicenter investigation of bone marrow transplantation for sickle cell disease. Volume 95 of Issue 6. Blood 2000. PMID: 10706855


  239. Reed W, Lane PA, Lorey F, Bojanowski J, Glass M, Louie RR, Lubin BH, Vichinsky EP. Sickle-cell disease not identified by newborn screening because of prior transfusion. Volume 136 of Issue 2. The Journal of pediatrics 2000. PMID: 10657834


  240. Hagar RW, Vichinsky EP. Major changes in sickle cell disease. Volume 47. Advances in pediatrics 2000. PMID: 10959446


  241. Hoppe C, Vichinsky E, Lewis B, Foote D, Styles L. Hydroxyurea and sodium phenylbutyrate therapy in thalassemia intermedia. Volume 62 of Issue 4. American journal of hematology 1999. PMID: 10589077


  242. Vichinsky EP, Neumayr LD, Haberkern C, Earles AN, Eckman J, Koshy M, Black DM. The perioperative complication rate of orthopedic surgery in sickle cell disease: report of the National Sickle Cell Surgery Study Group. Volume 62 of Issue 3. American journal of hematology 1999. PMID: 10539878


  243. Reed WF, Vichinsky EP. Transfusion practice for patients with sickle cell disease. Volume 6 of Issue 6. Current opinion in hematology 1999. PMID: 10546799


  244. Singer ST, Vichinsky EP. Bone disease in beta-thalassaemia. Volume 354 of Issue 9182. Lancet (London, England) 1999. PMID: 10489942


  245. Kinney TR, Helms RW, O'Branski EE, Ohene-Frempong K, Wang W, Daeschner C, Vichinsky E, Redding-Lallinger R, Gee B, Platt OS, Ware RE. Safety of hydroxyurea in children with sickle cell anemia: results of the HUG-KIDS study, a phase I/II trial. Pediatric Hydroxyurea Group. Volume 94 of Issue 5. Blood 1999. PMID: 10477679


  246. Harmatz P, Heyman MB, Cunningham J, Lee PD, Styles L, Quirolo K, Kopp-Hoolihan L, Ghiron J, Hintz RL, Vichinsky E. Effects of red blood cell transfusion on resting energy expenditure in adolescents with sickle cell anemia. Journal of pediatric gastroenterology and nutrition 1999. PMID: 10435647


  247. Morris C, Vichinsky E, Styles L. Clinician assessment for acute chest syndrome in febrile patients with sickle cell disease: is it accurate enough? Volume 34 of Issue 1. Annals of emergency medicine 1999. PMID: 10381996


  248. Reed W, Jagust W, Al-Mateen M, Vichinsky E. Role of positron emission tomography in determining the extent of CNS ischemia in patients with sickle cell disease. Volume 60 of Issue 4. American journal of hematology 1999. PMID: 10203099


  249. Kinney TR, Sleeper LA, Wang WC, Zimmerman RA, Pegelow CH, Ohene-Frempong K, Wethers DL, Bello JA, Vichinsky EP, Moser FG, Gallagher DM, DeBaun MR, Platt OS, Miller ST. Silent cerebral infarcts in sickle cell anemia: a risk factor analysis. The Cooperative Study of Sickle Cell Disease. Volume 103 of Issue 3. Pediatrics 1999. PMID: 10049969


  250. Waldron P, Pegelow C, Neumayr L, Haberkern C, Earles A, Wesman R, Vichinsky E. Tonsillectomy, adenoidectomy, and myringotomy in sickle cell disease: perioperative morbidity. Preoperative Transfusion in Sickle Cell Disease Study Group. Volume 21 of Issue 2. Journal of pediatric hematology/oncology 1999. PMID: 10206459


  251. Singer ST, Vichinsky EP. Deferoxamine treatment during pregnancy: is it harmful? Volume 60 of Issue 1. American journal of hematology 1999. PMID: 9883802


  252. Singer ST, Quirolo K, Nishi K, Hackney-Stephens E, Evans C, Vichinsky EP. Erythrocytapheresis for chronically transfused children with sickle cell disease: an effective method for maintaining a low hemoglobin S level and reducing iron overload. Volume 14 of Issue 3. Journal of clinical apheresis 1999. PMID: 10540366


  253. Reed W, Lee TH, Vichinsky EP, Lubin BH, Busch MP. Sample suitability for the detection of minor white cell populations (microchimerism) by polymerase chain reaction. Volume 38 of Issue 11-12. Transfusion 1998. PMID: 9838935


  254. Adams RJ, McKie VC, Hsu L, Files B, Vichinsky E, Pegelow C, Abboud M, Gallagher D, Kutlar A, Nichols FT, Bonds DR, Brambilla D. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. Volume 339 of Issue 1. The New England journal of medicine 1998. PMID: 9647873


  255. Weissman L, Treadwell M, Foote D, Heer N, Vichinsky EP. Approaches to working with adult thalassemia patients in pediatric settings. 1998. PMID: 9668599


  256. Lee YS, Kristovich KM, Ducore JM, Vichinsky E, Crouse VL, Glader BE, Amylon MD. Bone marrow transplant in thalassemia. A role for radiation? Volume 850. Annals of the New York Academy of Sciences 1998. PMID: 9668596


  257. Choy J, Yamashita RC, Foote D, Heer N, Vichinsky EP. Outreach strategies for Asian Pacific Island (API) communities. Volume 850. Annals of the New York Academy of Sciences 1998. PMID: 9705740


  258. Styles L, Lewis B, Foote D, Cuda L, Vichinsky EP. Preliminary report: hydroxyurea produces significant clinical response in thalassemia intermedia. Volume 850. Annals of the New York Academy of Sciences 1998. PMID: 9668584


  259. Rees DC, Styles L, Vichinsky EP, Clegg JB, Weatherall DJ. The hemoglobin E syndromes. Volume 850. Annals of the New York Academy of Sciences 1998. PMID: 9668555


  260. Vichinsky EP. The morbidity of bone disease in thalassemia. Volume 850. Annals of the New York Academy of Sciences 1998. PMID: 9668556


  261. Heer N, Choy J, Vichinsky EP. The social impact of migration on disease. Cooley's anemia, thalassemia, and new Asian immigrants. Volume 850. Annals of the New York Academy of Sciences 1998. PMID: 9668597


  262. Fridge JL, Vichinsky EP. Correction of the anemia of epidermolysis bullosa with intravenous iron and erythropoietin. Volume 132 of Issue 5. The Journal of pediatrics 1998. PMID: 9602203


  263. Golden C, Styles L, Vichinsky E. Acute chest syndrome and sickle cell disease. Volume 5 of Issue 2. Current opinion in hematology 1998. PMID: 9570700


  264. Adams RJ, McKie VC, Brambilla D, Carl E, Gallagher D, Nichols FT, Roach S, Abboud M, Berman B, Driscoll C, Files B, Hsu L, Hurlet A, Miller S, Olivieri N, Pegelow C, Scher C, Vichinsky E, Wang W, Woods G, Kutlar A, Wright E, Hagner S, Tighe F, Waclawiw MA. Stroke prevention trial in sickle cell anemia. Volume 19 of Issue 1. Controlled clinical trials 1998. PMID: 9492971


  265. Neumayr L, Koshy M, Haberkern C, Earles AN, Bellevue R, Hassell K, Miller S, Black D, Vichinsky E. Surgery in patients with hemoglobin SC disease. Preoperative Transfusion in Sickle Cell Disease Study Group. Volume 57 of Issue 2. American journal of hematology 1998. PMID: 9462540


  266. Hoppe C, Styles L, Vichinsky E. The natural history of sickle cell disease. Volume 10 of Issue 1. Current opinion in pediatrics 1998. PMID: 9529638


  267. Olivieri NF, Vichinsky EP. Hydroxyurea in children with sickle cell disease: impact on splenic function and compliance with therapy. Volume 20 of Issue 1. Journal of pediatric hematology/oncology 1998. PMID: 9482409


  268. Reed W, Vichinsky EP. New considerations in the treatment of sickle cell disease. Volume 49. Annual review of medicine 1998. PMID: 9509275


  269. Vichinsky EP. Hydroxyurea in children: present and future. Volume 34 of Issue 3 Suppl 3. Seminars in hematology 1997. PMID: 9317198


  270. Woods GM, Jorgensen JH, Waclawiw MA, Reid C, Wang W, Pegelow CH, Rogers ZR, Iyer RV, Holbrook CT, Kinney TR, Vichinsky E, DeBaun MR, Grossman NJ, Thomas MD, Falletta JM. Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II. Volume 19 of Issue 4. Journal of pediatric hematology/oncology 1997. PMID: 9256832


  271. Kelly P, Kurtzberg J, Vichinsky E, Lubin B. Umbilical cord blood stem cells: application for the treatment of patients with hemoglobinopathies. Volume 130 of Issue 5. The Journal of pediatrics 1997. PMID: 9152276


  272. Styles LA, Lubin B, Vichinsky E, Lawrence S, Hua M, Test S, Kuypers F. Decrease of very late activation antigen-4 and CD36 on reticulocytes in sickle cell patients treated with hydroxyurea. Volume 89 of Issue 7. Blood 1997. PMID: 9116302


  273. Vichinsky EP, Styles LA, Colangelo LH, Wright EC, Castro O, Nickerson B. Acute chest syndrome in sickle cell disease: clinical presentation and course. Cooperative Study of Sickle Cell Disease. Volume 89 of Issue 5. Blood 1997. PMID: 9057664


  274. Haberkern CM, Neumayr LD, Orringer EP, Earles AN, Robertson SM, Black D, Abboud MR, Koshy M, Idowu O, Vichinsky EP. Cholecystectomy in sickle cell anemia patients: perioperative outcome of 364 cases from the National Preoperative Transfusion Study. Preoperative Transfusion in Sickle Cell Disease Study Group. Volume 89 of Issue 5. Blood 1997. PMID: 9057634


  275. Pegelow CH, Colangelo L, Steinberg M, Wright EC, Smith J, Phillips G, Vichinsky E. Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia. Volume 102 of Issue 2. The American journal of medicine 1997. PMID: 9217567


  276. Styles LA, Vichinsky EP. New therapies and approaches to transfusion in sickle cell disease in children. Volume 9 of Issue 1. Current opinion in pediatrics 1997. PMID: 9088754


  277. Vichinsky E, Styles L. Pulmonary complications. Volume 10 of Issue 6. Hematology/oncology clinics of North America 1996. PMID: 8956016


  278. Bjornson AB, Falletta JM, Verter JI, Buchanan GR, Miller ST, Pegelow CH, Iyer RV, Johnstone HS, DeBaun MR, Wethers DL, Wang WC, Woods GM, Holbrook CT, Becton DL, Kinney TR, Reaman GH, Kalinyak K, Grossman NJ, Vichinsky E, Reid CD. Serotype-specific immunoglobulin G antibody responses to pneumococcal polysaccharide vaccine in children with sickle cell anemia: effects of continued penicillin prophylaxis. Volume 129 of Issue 6. The Journal of pediatrics 1996. PMID: 8969724


  279. Claster S, Vichinsky E. First report of reversal of organ dysfunction in sickle cell anemia by the use of hydroxyurea: splenic regeneration. Volume 88 of Issue 6. Blood 1996. PMID: 8822912


  280. Styles LA, Vichinsky EP. Core decompression in avascular necrosis of the hip in sickle-cell disease. Volume 52 of Issue 2. American journal of hematology 1996. PMID: 8638629


  281. Walters MC, Patience M, Leisenring W, Eckman JR, Buchanan GR, Rogers ZR, Olivieri NE, Vichinsky E, Davies SC, Mentzer WC, Powars D, Scott JP, Bernaudin F, Ohene-Frempong K, Darbyshire PJ, Wayne A, Roberts IA, Dinndorf P, Brandalise S, Sanders JE, Matthews DC, Appelbaum FR, Storb R, Sullivan KM. Barriers to bone marrow transplantation for sickle cell anemia. Volume 2 of Issue 2. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 1996. PMID: 9118298


  282. Moser FG, Miller ST, Bello JA, Pegelow CH, Zimmerman RA, Wang WC, Ohene-Frempong K, Schwartz A, Vichinsky EP, Gallagher D, Kinney TR. The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease. Volume 17 of Issue 5. AJNR. American journal of neuroradiology 1996. PMID: 8733975


  283. Styles LA, Schalkwijk CG, Aarsman AJ, Vichinsky EP, Lubin BH, Kuypers FA. Phospholipase A2 levels in acute chest syndrome of sickle cell disease. Volume 87 of Issue 6. Blood 1996. PMID: 8630425


  284. Shafer FE, Lorey F, Cunningham GC, Klumpp C, Vichinsky E, Lubin B. Newborn screening for sickle cell disease: 4 years of experience from California's newborn screening program. Volume 18 of Issue 1. Journal of pediatric hematology/oncology 1996. PMID: 8556368


  285. Styles LA, Vichinsky EP. Ototoxicity in hemoglobinopathy patients chelated with desferrioxamine. Volume 18 of Issue 1. Journal of pediatric hematology/oncology 1996. PMID: 8556369


  286. Koshy M, Weiner SJ, Miller ST, Sleeper LA, Vichinsky E, Brown AK, Khakoo Y, Kinney TR. Surgery and anesthesia in sickle cell disease. Cooperative Study of Sickle Cell Diseases. Volume 86 of Issue 10. Blood 1995. PMID: 7579333


  287. Falletta JM, Woods GM, Verter JI, Buchanan GR, Pegelow CH, Iyer RV, Miller ST, Holbrook CT, Kinney TR, Vichinsky E. Discontinuing penicillin prophylaxis in children with sickle cell anemia. Prophylactic Penicillin Study II. Volume 127 of Issue 5. The Journal of pediatrics 1995. PMID: 7472817


  288. Vichinsky EP, Haberkern CM, Neumayr L, Earles AN, Black D, Koshy M, Pegelow C, Abboud M, Ohene-Frempong K, Iyer RV. A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease. The Preoperative Transfusion in Sickle Cell Disease Study Group. Volume 333 of Issue 4. The New England journal of medicine 1995. PMID: 7791837


  289. Gill FM, Sleeper LA, Weiner SJ, Brown AK, Bellevue R, Grover R, Pegelow CH, Vichinsky E. Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell Disease. Volume 86 of Issue 2. Blood 1995. PMID: 7606007


  290. Pegelow CH, Adams RJ, McKie V, Abboud M, Berman B, Miller ST, Olivieri N, Vichinsky E, Wang W, Brambilla D. Risk of recurrent stroke in patients with sickle cell disease treated with erythrocyte transfusions. Volume 126 of Issue 6. The Journal of pediatrics 1995. PMID: 7776091


  291. Lang T, Berquist WE, So SK, Cox KL, Rich EJ, Vichinsky E, Concepcion W, Esquivel CO. Liver transplantation in a child with sickle cell anemia. Volume 59 of Issue 10. Transplantation 1995. PMID: 7770941


  292. Aquino SL, Gamsu G, Fahy JV, Claster S, Embury SH, Mentzer WC, Vichinsky EP. Chronic pulmonary disorders in sickle cell disease: findings at thin-section CT. Volume 193 of Issue 3. Radiology 1994. PMID: 7972829


  293. Styles LA, Vichinsky E. Effects of a long-term transfusion regimen on sickle cell-related illnesses. Volume 125 of Issue 6 Pt 1. The Journal of pediatrics 1994. PMID: 7996363


  294. Vichinsky E, Williams R, Das M, Earles AN, Lewis N, Adler A, McQuitty J. Pulmonary fat embolism: a distinct cause of severe acute chest syndrome in sickle cell anemia. Volume 83 of Issue 11. Blood 1994. PMID: 8193347


  295. Shafer FE, Vichinsky E. New advances in the pathophysiology and management of sickle cell disease. Volume 1 of Issue 2. Current opinion in hematology 1994. PMID: 9371271


  296. Vichinsky EP, Lubin BH. A cautionary note regarding hydroxyurea in sickle cell disease. Volume 83 of Issue 4. Blood 1994. PMID: 7509209


  297. Mentzer WC, Heller S, Pearle PR, Hackney E, Vichinsky E. Availability of related donors for bone marrow transplantation in sickle cell anemia. Volume 16 of Issue 1. The American journal of pediatric hematology/oncology 1994. PMID: 8311169


  298. Perrine SP, Olivieri NF, Faller DV, Vichinsky EP, Dover GJ, Ginder GD. Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders. Volume 16 of Issue 1. The American journal of pediatric hematology/oncology 1994. PMID: 7508690


  299. Lorey F, Cunningham G, Shafer F, Lubin B, Vichinsky E. Universal screening for hemoglobinopathies using high-performance liquid chromatography: clinical results of 2.2 million screens. Volume 2 of Issue 4. European journal of human genetics : EJHG 1994. PMID: 7704556


  300. Lorey FW, Cunningham GC, Vichinsky E, Lubin B, Shafer F, Eastman J. Detection of Hb E/beta-thalassemia versus homozygous EE using high-performance liquid chromatography results from newborns. Volume 49 of Issue 1. Biochemical medicine and metabolic biology 1993. PMID: 7679916