Jenise Wong, MD, PhD

My research goal is to improve outcomes for people with diabetes through optimal use of diabetes technologies. Management of diabetes is difficult, with self-management and adherence changing as a child progresses from childhood through adolescence and young adulthood. Tools that assist patients with diabetes are constantly emerging, which range from devices for insulin delivery, such as insulin pumps, continuous glucose monitoring (CGM) devices, and automated insulin delivery systems, to mobile phone and internet applications designed to improve self-management and provide support. My goal is to understand and optimize the use of technology to improve clinical, behavioral, and patient-centered outcomes in youth with diabetes. With formal training in basic science and clinical research, I have expertise in quantitative and qualitative methods, as well as quality improvement methodology. My research group has investigated insulin pump and CGM use, barriers to use, and reasons for device discontinuation in type 1 diabetes (T1D) and type 2 diabetes (T2D). We have explored individual, family, clinic, and system factors that influence use of technology, including social determinants of health. We have conducted pilot clinical trials of diabetes device visualization software and devices, and we reported feasibility of using new tools. In my current work, we are exploring factors in youth with diabetes that contribute to less optimal outcomes, focusing on patients and families experiencing chronic health conditions and social vulnerabilities, most of whom are racially and/or ethnically marginalized and publicly insured. We are also currently investigating the feasibility of initiating hybrid closed-loop technology in publicly insured children with T1D. In addition, we are working with collaborators at Children's Hospital of Los Angeles and University of California Davis to improve education and use of diabetes technology among Latinx adolescents, through the use of virtual peer groups. All of this work will lead to more consistent, sustained use of diabetes device technology and improvements in clinical and patient-centered outcomes in young people with diabetes.

In addition to my research, I am an Associate Program Director for the Pediatric Endocrinology Fellowship Program. I am also the Director of Quality and Safety for Pediatric Diabetes and Endocrinology at Benioff Children's Hospital - San Francisco.
Education
10/2020 - Diversity, Equity, and Inclusion Champion Training, University of California
Pediatric Endocrinology Fellowship, 2011 - , University of California San Francisco
General Pediatrics Residency, 2009 - , Boston Children's Hospital/Boston Medical Center
M.D., 2006 - School of Medicine, Stanford University
Ph.D., 2002 - Department of Genetics, Harvard University
Honors and Awards
  • Hellman Family Award for Early Career Faculty, Hellman Fellows Fund, 2015-2016
  • Helmsley Charitable Trust Abstract Award, The Leona M. and Harry B. Helmsley Charitable Trust and The Endocrine Society, 2014
  • Clinical Research Grant, Genentech Center for Clinical Research in Endocrinology, 2011-2012
  • Research Fellowship Award, Pediatric Endocrine Society, 2011-2012
Websites
  1. Abby Walch, Janet Y. Lee, Jenise C. Wong, Madeline Deutsch, Diane Ehrensaft, Megumi Okumura, Stephen M. Rosenthal. Clinicians Report Less Comfort in Provision of Medical Care to Nonbinary Transgender Youth. Transgender health 2023. PMID:


  2. ALISON REED, JENISE C. WONG, DIANA NARANJO, RAHUL PADMANABHAN, RYAN NAVARRO, ERIN KOBLINSKI, KRISTEN A. TORRES, CRISTIAN CRUZ, MICHAEL A. HARRIS, DAVID V. WAGNER. 53-LB: Do the Right Thing—Intensive Intervention and Resulting Costs for Youth with High Social Risk and Type 1 Diabetes (T1D). Diabetes 2023. PMID:


  3. KEVIN YEN, SONALI BELAPURKAR, JEANNIE G. HICKEY, LOREN YGLECIAS, KAVENPREET S. BAL, LOIS LYBECK CARELLI, CRYSTAL M. LOUCEL, MAYA LODISH, JENISE C. WONG. 1123-P: Pilot Study of Early Adoption of Automated Insulin Delivery in Under-Resourced Youth. Diabetes 2023. PMID:


  4. DAVID V. WAGNER, JENNIFER RAYMOND, JENISE C. WONG, DIANA NARANJO, ALISON REED, KRISTEN A. TORRES, SYDNEY MELNICK, SUSANNE MITCHELL, LOREN YGLECIAS, JAQUELIN FLORES GARCIA, ALEJANDRA TORRES SANCHEZ, ANDREA BONILLA OSPINA, MARK A. CLEMENTS, MICHAEL A. HARRIS. 160-OR: Youth with T1D and Elevated A1C —Pandemic Experiences and Psychosocial Factors. Diabetes 2023. PMID:


  5. DAVID V. WAGNER, MARK A. CLEMENTS, JENNIFER RAYMOND, JENISE C. WONG, DIANA NARANJO, ALISON REED, KRISTEN A. TORRES, SYDNEY MELNICK, JAQUELIN FLORES GARCIA, ANDREA BONILLA OSPINA, MARISA E. HILLIARD, MICHAEL A. HARRIS. 54-LB: The Kids Are Not Alright—Capturing the Need for Effective Intervention for Adolescents with Elevated A1C. Diabetes 2023. PMID:


  6. DAVID V. WAGNER, MEGAN PERRY, MARK A. CLEMENTS, JENISE C. WONG, DIANA NARANJO, ALISON REED, CELESTE JENISCH, CRISTIAN CRUZ, SUSANNE MITCHELL, LOREN YGLECIAS, JAQUELIN FLORES GARCIA, ALEJANDRA TORRES SANCHEZ, ANDREA BONILLA OSPINA, JENNIFER RAYMOND, MICHAEL A. HARRIS. 673-P: Youth with Type 1 Diabetes and Elevated A1C during the Coronavirus Disease-2019 (COVID-19) Pandemic—Examination of Family, Caregiver, and Medical Team Factors. Diabetes 2023. PMID:


  7. ALISON REED, CAROLINA E. NOYA, DAVID V. WAGNER, JENNIFER H. LIM, VIVIEN GLOCKER, KAVENPREET S. BAL, MARYSOL GONZALES GRANADOS, ANNEMARIE STONE, MAUREEN T. MCGRATH, MICHAEL A. HARRIS, MAYA LODISH, JENISE C. WONG. 727-P: Improvement in Psychosocial Functioning of Youth with Diabetes and Their Caregivers with Multiple Social Risk Factors. Diabetes 2023. PMID:


  8. Cassidy Puckett, Jenise C. Wong, Sloan Talbot, Hyojin Jennifer Min, Nora Chokr. Institutional role conflict in the digital age: The case of diabetes management at school. SSM - Qualitative Research in Health 2023. PMID:



  9. Cassidy Puckett, Jenise C. Wong, Sloan Talbot, Hyojin Jennifer Min, Nora Chokr. Institutional role conflict in the digital age: The case of diabetes management at school SSM - Qualitative Research in Health 2022. PMID:



  10. Mann EA, Rompicherla S, Gallagher MP, Alonso GT, Fogel NR, Simmons J, Wood JR, Wong JC, Noor N, Gomez P, Daniels M, Ebekozien O. Comorbidities increase COVID-19 hospitalization in young people with type 1 diabetes. Pediatric diabetes 2022. PMID: 36054578



  11. LOREN YGLECIAS, ALISON REED, CAROLINA E. NOYA, MAUREEN T. MCGRATH, ANNEMARIE STONE, MAYA LODISH, KIMBERLY B. SPIRO, INGRID C. GOMEZ, MICHAEL A. HARRIS, DAVID V. WAGNER, JENISE C. WONG. 1008-P: Trends in Improvement in Clinical Outcomes and Health Care Access in Underrepresented Youth with Type 1 Diabetes (T1D). Diabetes 2022. PMID:


  12. DAVID V. WAGNER, MARK A. CLEMENTS, JENNIFER RAYMOND, JENISE C. WONG, ALISON REED, DIANA NARANJO, CELESTE JENISCH, CRISTIAN CRUZ, SUSANNE MITCHELL, LOREN YGLECIAS, JAQUELIN J. FLORES GARCIA, ELIZABETH SALCEDO-RODRIGUEZ, ALEJANDRA TORRES SANCHEZ, POOJITA DASIKA, JULIA VIANA, DAVID D. WILLIAMS, DIANA FERRO, MICHAEL A. HARRIS. 631-P: Youth with Type 1 Diabetes (T1D) and High Social Risk: Predictors of Glycemic Control. Diabetes 2022. PMID:


  13. DAVID V. WAGNER, JENISE C. WONG, ALISON REED, LOREN YGLECIAS, ANDREA BONILLA OSPINA, DIANA NARANJO, CAROLINA E. NOYA, JULIA VIANA, CELESTE JENISCH, CRISTIAN CRUZ, MICHAEL A. HARRIS. 632-P: Youth with T1D and High Social Risk Enrolled in an Intensive Community-Based Intervention: Two-Region Comparison of Risk. Diabetes 2022. PMID:



  14. Van Name MA, Kanapka LG, DiMeglio LA, Miller KM, Albanese-O'Neill A, Commissariat P, Corathers SD, Harrington KR, Hilliard ME, Anderson BJ, Kelley JC, Laffel LM, MacLeish SA, Nathan BM, Tamborlane WV, Wadwa RP, Willi SM, Williams KM, Wintergerst KA, Woerner S, Wong JC, DeSalvo DJ. Long-term Continuous Glucose Monitor Use in Very Young Children With Type 1 Diabetes: One-Year Results From the SENCE Study. 2022. PMID: 35343269


  15. Nguyen KT, Xu NY, Buckingham BA, Chattaraj S, Cohen O, Heinemann L, Pickup J, Svensson J, Vigersky RA, Wong JC, Ziegler R. Improving the Patient Experience With Longer Wear Infusion Sets Symposium Report. 2022. PMID: 35227075


  16. TEJASWI KOMPALA, JENISE C. WONG, AARON B. NEINSTEIN. 636-P: Diabetes Providers Value CGM Data Despite Challenges in Data Review Process. Diabetes 2021. PMID:





  17. Alonso GT, Ebekozien O, Gallagher MP, Rompicherla S, Lyons SK, Choudhary A, Majidi S, Pinnaro CT, Balachandar S, Gangat M, Curda Roberts AJ, Marks BE, Creo A, Sanchez J, Seeherunvong T, Jimenez-Vega J, Patel NS, Wood JR, Gabriel L, Sumpter KM, Wilkes M, Rapaport R, Cymbaluk A, Wong JC, Sanda S, Albanese-O'neill A. Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes. Journal of diabetes 2021. PMID: 33855813


  18. Ebekozien O, Agarwal S, Noor N, Albanese-O'Neill A, Wong JC, Seeherunvong T, Sanchez J, DeSalvo D, Lyons SK, Majidi S, Wood JR, Acharya R, Aleppo G, Sumpter KM, Cymbaluk A, Shah NA, Van Name M, Cruz-Aviles L, Alonso GT, Gallagher MP, Sanda S, Feuer AJ, Cossen K, Rioles N, Jones NY, Kamboj MK, Hirsch IB. Inequities in Diabetic Ketoacidosis Among Patients With Type 1 Diabetes and COVID-19: Data From 52 US Clinical Centers. The Journal of clinical endocrinology and metabolism 2021. PMID: 33410917





  19. JENNIFER ZABINSKY, HALEY HOWELL, ALIREZA GHEZAVATI, DANA M. LEWIS, ANDREW NGUYEN, JENISE C. WONG. 988-P: Do-It-Yourself Artificial Pancreas Systems for Type 1 Diabetes Reduce Hyperglycemia without Increasing Hypoglycemia. Diabetes 2020. PMID:


  20. DiMeglio LA, Kanapka LG, DeSalvo DJ, Anderson BJ, Harrington KR, Hilliard ME, Laffel LM, Tamborlane WV, Van Name MA, Wadwa RP, Willi SM, Woerner S, Wong JC, Miller KM, SENCE Study Group. Time spent outside of target glucose range for young children with type 1 diabetes: a continuous glucose monitor study. Diabetic medicine : a journal of the British Diabetic Association 2020. PMID: 32096282



  21. JENNIFER SHERR, NICOLE C. FOSTER, KATHLEEN BETHIN, LARRY A. FOX, LUCY D. MASTRANDREA, BRANDON M. NATHAN, MARIA JOSE REDONDO, JANET SILVERSTEIN, JILL SIMMONS, MARK A. CLEMENTS, WILLIAM V. TAMBORLANE, KATHRYN M. THRAILKILL, JENISE C. WONG, JAMIE WOOD. 1355-P: HbA1c Trajectories from Time of Diagnosis in Youth with T1D. Diabetes 2019. PMID:


  22. JENISE C. WONG, FATEMA ABDULHUSSEIN, BRITTANY J. YEUNG, EDGAR J. VELAZQUEZ. 942-P: Caregivers of Children with Type 1 Diabetes Value Real-Time Functions of Continuous Glucose Monitoring. Diabetes 2019. PMID:


  23. Priya Prahalad, Nilanjana Ray, Jenise C Wong, Cari Berget, Anna Lindholm Olinder, Jayanti J Rangasami, Bruce R King, Asma Deeb, Juliana Chizo Agwu. ISPAD Annual Conference 2018 Highlights. Pediatric diabetes 2019. PMID:



  24. Varni JW, Delamater AM, Hood KK, Raymond JK, Chang NT, Driscoll KA, Wong JC, Yi-Frazier JP, Grishman EK, Faith MA, Corathers SD, Kichler JC, Miller JL, Doskey EM, Heffer RW, Wilson DP, Pediatric Quality of Life Inventory 3.2 Diabetes Module Testing Study Consortium. PedsQL 3.2 Diabetes Module for Children, Adolescents, and Young Adults: Reliability and Validity in Type 1 Diabetes. Diabetes care 2018. PMID: 30061317


  25. Varni JW, Delamater AM, Hood KK, Driscoll KA, Wong JC, Adi S, Yi-Frazier JP, Grishman EK, Faith MA, Corathers SD, Kichler JC, Miller JL, Raymond JK, Doskey EM, Aguirre V, Heffer RW, Wilson DP, Pediatric Quality of Life Inventory 3.2 Diabetes Module Testing Study Consortium. Diabetes management mediating effects between diabetes symptoms and health-related quality of life in adolescents and young adults with type 1 diabetes. Pediatric diabetes 2018. PMID: 29927039


  26. Varni JW, Delamater AM, Hood KK, Raymond JK, Driscoll KA, Wong JC, Adi S, Yi-Frazier JP, Grishman EK, Faith MA, Corathers SD, Kichler JC, Miller JL, Doskey EM, Aguirre VP, Heffer RW, Wilson DP, Pediatric Quality of Life Inventory™ 3.2 Diabetes Module Testing Study Consortium. Diabetes symptoms predictors of health-related quality of life in adolescents and young adults with type 1 or type 2 diabetes. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 2018. PMID: 29785681


  27. CASSIDY PUCKETT, JENISE C. WONG. Clinical Practice Factors That Define Insulin Pump Readiness. Diabetes 2018. PMID:


  28. JAMIE WOOD, CLAIRE BOYLE, MARYANNE QUINN, JENISE C. WONG, MICHAEL J. HALLER, BRYCE A. NELSON, MICHAEL J. HALLER, DESMOND SCHATZ, WILLIAM V. TAMBORLANE, LARRY FOX, PRIYA PRAHALAD, SARAH CORATHERS, DAVID M. MAAHS, GUY T. ALONSO, DANIEL J. DESALVO, R. PAUL WADWA, LINDA DIMEGLIO. Impact of Target HbA1c Change in Pediatric Participants in the T1D Exchange Clinic Registry. Diabetes 2018. PMID:


  29. JENISE C. WONG, ZARA IZADI, SHANNON M. SCHROEDER, MARIE NADER, HYOJIN J. MIN, AARON B. NEINSTEIN, SALEH ADI. Use of the Tidepool Platform to Collect, Integrate, and Visualize Diabetes Device Data in a Pediatric Clinic Setting. Diabetes 2018. PMID:


  30. Klonoff DC, Kerr D, Wong JC, Pavlovic Y, Koliwad S, Hu J, Salber P, Aguilera A, Long W, Hamilton G, Chen KY, Adi S. Digital Diabetes Congress 2017. Journal of diabetes science and technology 2017. PMID: 28786320


  31. Wong JC, Neinstein AB, Look H, Arbiter B, Chokr N, Ross C, Adi S. Pilot Study of a Novel Application for Data Visualization in Type 1 Diabetes. Journal of diabetes science and technology 2017. PMID: 28617628


  32. Wong JC, Boyle C, DiMeglio LA, Mastrandrea LD, Abel KL, Cengiz E, Cemeroglu PA, Aleppo G, Largay JF, Foster NC, Beck RW, Adi S, T1D Exchange Clinic Network. Evaluation of Pump Discontinuation and Associated Factors in the T1D Exchange Clinic Registry. Journal of diabetes science and technology 2016. PMID: 27595711




  33. Redondo MJ, Foster NC, Libman IM, Mehta SN, Hathway JM, Bethin KE, Nathan BM, Ecker MA, Shah AC, DuBose SN, Tamborlane WV, Hoffman RP, Wong JC, Maahs DM, Beck RW, DiMeglio LA. Prevalence of cardiovascular risk factors in youth with type 1 diabetes and elevated body mass index. Acta diabetologica 2015. PMID: 26077171


  34. Wong JC, Foster NC, Maahs DM, Raghinaru D, Bergenstal RM, Ahmann AJ, Peters AL, Bode BW, Aleppo G, Hirsch IB, Kleis L, Chase HP, DuBose SN, Miller KM, Beck RW, Adi S, T1D Exchange Clinic Network. Response to comment on Wong et al. Real-time continuous glucose monitoring among participants in the T1D exchange clinic registry. Diabetes Care 2014;37:2702-2709. Diabetes care 2015. PMID: 25805875



  35. Wong JC, Foster NC, Maahs DM, Raghinaru D, Bergenstal RM, Ahmann AJ, Peters AL, Bode BW, Aleppo G, Hirsch IB, Kleis L, Chase HP, DuBose SN, Miller KM, Beck RW, Adi S, T1D Exchange Clinic Network. Real-time continuous glucose monitoring among participants in the T1D Exchange clinic registry. Diabetes care 2014. PMID: 25011947


  36. Jonathan F. Russell, Jenise C. Wong, Melvin M. Grumbach. Chapter 3J Aromatase Deficiency and Aromatase Excess. Genetic Steroid Disorders 2014. PMID:


  37. Campbell MS, Schatz DA, Chen V, Wong JC, Steck A, Tamborlane WV, Smith J, Beck RW, Cengiz E, Laffel LM, Miller KM, Haller MJ, T1D Exchange Clinic Network. A contrast between children and adolescents with excellent and poor control: the T1D Exchange clinic registry experience. Pediatric diabetes 2013. PMID: 23957219


  38. Cengiz E, Xing D, Wong JC, Wolfsdorf JI, Haymond MW, Rewers A, Shanmugham S, Tamborlane WV, Willi SM, Seiple DL, Miller KM, DuBose SN, Beck RW, T1D Exchange Clinic Network. Severe hypoglycemia and diabetic ketoacidosis among youth with type 1 diabetes in the T1D Exchange clinic registry. Pediatric diabetes 2013. PMID: 23469984


  39. Palmer RE, Lee SB, Wong JC, Reynolds PA, Zhang H, Truong V, Oliner JD, Gerald WL, Haber DA. Induction of BAIAP3 by the EWS-WT1 chimeric fusion implicates regulated exocytosis in tumorigenesis. Cancer cell 2002. PMID: 12498718


  40. Wong JC, Lee SB, Bell MD, Reynolds PA, Fiore E, Stamenkovic I, Truong V, Oliner JD, Gerald WL, Haber DA. Induction of the interleukin-2/15 receptor beta-chain by the EWS-WT1 translocation product. Oncogene 2002. PMID: 11960373


  41. Bönnemann CG, Wong J, Jones KJ, Lidov HG, Feener CA, Shapiro F, Darras BT, Kunkel LM, North KN. Primary gamma-sarcoglycanopathy (LGMD 2C): broadening of the mutational spectrum guided by the immunohistochemical profile. Neuromuscular disorders : NMD 2002. PMID: 11801399


  42. Lee SB, Huang K, Palmer R, Truong VB, Herzlinger D, Kolquist KA, Wong J, Paulding C, Yoon SK, Gerald W, Oliner JD, Haber DA. The Wilms tumor suppressor WT1 encodes a transcriptional activator of amphiregulin. Cell 1999. PMID: 10490105



  43. Bönnemann CG, Wong J, Ben Hamida C, Hamida MB, Hentati F, Kunkel LM. LGMD 2E in Tunisia is caused by a homozygous missense mutation in beta-sarcoglycan exon 3. Neuromuscular disorders : NMD 1998. PMID: 9631401


  44. Maheswaran S, Englert C, Zheng G, Lee SB, Wong J, Harkin DP, Bean J, Ezzell R, Garvin AJ, McCluskey RT, DeCaprio JA, Haber DA. Inhibition of cellular proliferation by the Wilms tumor suppressor WT1 requires association with the inducible chaperone Hsp70. Genes & development 1998. PMID: 9553041