Research

FACULTY RESEARCH

The division has a long history of basic and clinical investigation. Our current faculty research interests include neuro-endocrinology, stem cell biology, immunotherapeutics in autoimmune diseases like type 1 diabetes, skeletal health, pharmacogenomics, and the use of technology in the treatment of type 1 and type 2 diabetes.

Please refer to our Faculty page and  UCSF profiles for further information about our faculty members’ research interests.

RESEARCH EXPERIENCES FOR FELLOWS AND TRAINEES

The nature of our training program allows our fellows have the time and flexibility to explore scholarly interests outside of their clinical training, which is central to the fellowship experience at UCSF.  Trainees can pursue formal training, develop skills, and conduct independent projects in the clinical and/or basic research sciences, quality and systems improvement, and/or education (see Scholarly Activity on the Program Description page). 

In addition to the Pediatric Endocrinology faculty, the following faculty have mentored pediatric endocrine fellows in past years:

  • Mark S. Anderson, MD, PhD. Professor of Medicine, Director of the Diabetes Center
  • Dan D. Bikle, MD, PhD. Professor of Medicine and Dermatology
  • Jeffrey A. Bluestone, Ph.D. Professor of Medicine and Pathology, Diabetes Center
  • Donna M. Ferriero, MD. Professor of Neurology and Pediatrics
  • Susan J. Fischer, PhD. Professor of Cell and Tissue Biology
  • Michael S. German, MD. Professor of Medicine, Diabetes Center
  • Linda C. Giudice, MD, PhD. Professor and Chair of Obstetrics, Gynecology, and Reproductive Sciences
  • Ira D. Goldfine, MD. Professor of Medicine and Physiology
  • Matthias Hebrok, PhD. Professor of Medicine, Diabetes Center
  • Healther Huddleston, MD. Professor of Obstetrics, Gynecology, and Reproductive Sciences
  • Holly Ingraham, PhD. Professor of Cellular and Molecular Pharmacology
  • Synthia H. Mellon, PhD. Professor of Obstetrics, Gynecology, and Reproductive Sciences
  • Thomas B. Newman, MD, MPH. Professor of Pediatrics and Epidemiology & Biostatistics
  • Anthony A. Portale, MD. Professor of Pediatrics and Medicine
  • Neil J. Risch, PhD. Professor of Genetics
  • Dolores M. Shoback, MD. Professor of Medicine
  • Hilary Seligman, MD, MAS. Professor of Medicine and Epidemiology & Biostatistics
  • Deepak Srivastava, MD. Professor of Pediatrics
  • Christian Vaisse, MD, PhD. Professor of Medicine, Diabetes Center
  • Allison Xu, Ph.D. Professor of Anatomy, Diabetes Center
  • Keith Yamamoto, Ph.D. Professor of Cellular/Molecular Pharmacology and Biochemistry/Biophysics

 

CLINICAL RESEARCH OPPORTUNITIES FOR PATIENTS AND FAMILIES

Thank you to our patients and families interested in participating in clinical research studies!  The following are research opportunities currently recruiting participants.  Please reach out to the study contact if you have questions and/or are interested in participating.

Study title

Participants

UCSF Principal Investigator

Contact

TrialNet Pathway to Prevention Study

Age 2.5 to 45 years with relatives with T1D

Stephen Gitelman, MD

[email protected]

TOPPLE T1D: A multiple ascending dose trial investigating safety, tolerability and pharmacokinetics of NNC0361-0041 administered subcutaenously to patients with type 1 diabetes mellitus

Age 18 to 45 years with T1D, diagnosed within the past 48 months

Stephen Gitelman, MD

[email protected]

Postprandial glucose control using an extended bolus for high-fat high protein meals in a closed loop system in patients with Type 1 Diabetes

Age 13 to 18 years with T1D using Control-IQ

Laya Ekhlaspour, MD

[email protected]

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Pediatric Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label Treatment

Age 2 to 17 years with congential adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency

Maya Lodish, MD

[email protected]

A Randomized Comparative Study Between Liquid (Tirosint®-SOL) and Tablet Formulations of Levothyroxine in Neonates and Infants with Congenital Hypothyroidism (CH)

Age 0 to 9 months with congenital hypothyroidism

Maya Lodish, MD

[email protected]

A study to develop a population pharmacokinetic model to describe the relationship between body mass index and metformin clearance in youth with type 2 diabetes (POP-PK Kids)

Youth with type 2 diabetes

Shylaja Srinivasan, MD

[email protected]

Type 1 Diabetes Exercise Initiative Pediatric Study

Age 12 to 17 years with T1D

Jenise Wong, MD PhD

[email protected] / www.jaeb.org/t1dexip