Walter Miller, MD

  1. Miller WL. Thirty years of StAR gazing: expanding the universe of the steroidogenic acute regulatory protein. The Journal of endocrinology 2025. PMID: 39773408


  2. Miller WL, Pandey AV, Flück CE. Disordered electron transfer: New forms of defective steroidogenesis and mitochondriopathy. The Journal of clinical endocrinology and metabolism 2024. PMID: 39574227


  3. Miller WL, White PC. History of Adrenal Research: From Ancient Anatomy to Contemporary Molecular Biology. Endocrine reviews 2023. PMID: 35947694


  4. Miller WL, White PC. A Brief History of Congenital Adrenal Hyperplasia. Hormone research in paediatrics 2022. PMID: 36446323


  5. Oberfield SE, Rogol AD, Miller WL. A Brief History of the Pediatric Endocrine Society (PES). Hormone research in paediatrics 2022. PMID: 36446318


  6. Oberfield SE, Rogol AD, Miller WL. Celebrating 50 Years of the Pediatric Endocrine Society (PES): Histories of Pediatric Endocrine Topics. Hormone research in paediatrics 2022. PMID: 36446325


  7. Miller WL, Imel EA. Rickets, Vitamin D, and Ca/P Metabolism. Hormone research in paediatrics 2022. PMID: 36446330


  8. Claahsen-van der Grinten HL, Speiser PW, Ahmed SF, Arlt W, Auchus RJ, Falhammar H, Flück CE, Guasti L, Huebner A, Kortmann BBM, Krone N, Merke DP, Miller WL, Nordenström A, Reisch N, Sandberg DE, Stikkelbroeck NMML, Touraine P, Utari A, Wudy SA, White PC. Congenital adrenal hyperplasia - current insights in pathophysiology, diagnostics and management. Endocrine reviews 2021. PMID: 33961029


  9. Miller WL. Steroidogenic electron-transfer factors and their diseases. Annals of pediatric endocrinology & metabolism 2021. PMID: 34610701


  10. Bhargava A, Arnold AP, Bangasser DA, Denton KM, Gupta A, Hilliard Krause LM, Mayer EA, McCarthy M, Miller WL, Raznahan A, Verma R. Considering Sex as a Biological Variable in Basic and Clinical Studies: An Endocrine Society Scientific Statement. Endocrine reviews 2021. PMID: 33704446


  11. Bose HS, Whittal RM, Marshall B, Rajapaksha M, Wang NP, Bose M, Perry EW, Zhao ZQ, Miller WL. A Novel Mitochondrial Complex of Aldosterone Synthase, Steroidogenic Acute Regulatory Protein, and Tom22 Synthesizes Aldosterone in the Rat Heart. The Journal of pharmacology and experimental therapeutics 2021. PMID: 33526603


  12. Miller WL. Tenascin-X-Discovery and Early Research. Frontiers in immunology 2021. PMID: 33505400


  13. Miller WL. Congenital Adrenal Hyperplasia: Time to Replace 17OHP with 21-Deoxycortisol. Hormone research in paediatrics 2019. PMID: 31450227


  14. Speiser PW, Auchus RJ, Merke DP, Miller WL, White PC. Response to Letter to the Editor: "Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline". The Journal of clinical endocrinology and metabolism 2019. PMID: 30561699


  15. Miller WL, Auchus RJ. The "backdoor pathway" of androgen synthesis in human male sexual development. PLoS biology 2019. PMID: 30943210


  16. Speiser PW, Arlt W, Auchus RJ, Baskin LS, Conway GS, Merke DP, Meyer-Bahlburg HFL, Miller WL, Murad MH, Oberfield SE, White PC. Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline. The Journal of clinical endocrinology and metabolism 2018. PMID: 30272171


  17. Miller WL. MECHANISMS IN ENDOCRINOLOGY: Rare defects in adrenal steroidogenesis. European journal of endocrinology 2018. PMID: 29880708


  18. Miller WL, Merke DP. Tenascin-X, Congenital Adrenal Hyperplasia, and the CAH-X Syndrome. Hormone research in paediatrics 2018. PMID: 29734195


  19. Miller WL. The Hypothalamic-Pituitary-Adrenal Axis: A Brief History. Hormone research in paediatrics 2018. PMID: 29719288


  20. Miller WL. Steroidogenesis: Unanswered Questions. Trends in endocrinology and metabolism: TEM 2017. PMID: 29031608


  21. Miller WL. Melvin M. Grumbach, MD, 1925-2016?. Hormone research in paediatrics 2017. PMID: 28365711


  22. Miller WL. In Memoriam: Melvin M. Grumbach, MD, (1925-2016) Pediatric Endocrinologist, Scientist, Educator, Leader. Pediatric endocrinology reviews : PER 2017. PMID: 28508597


  23. Miller WL. In Memoriam: Melvin M. Grumbach (1925-2016). Endocrine reviews 2016. PMID: 27915503


  24. Miller WL. In Memoriam: Melvin M. Grumbach (1925-2016). Endocrinology 2016. PMID: 27911151


  25. Miller WL. Introduction to the 2016 Keith L. Parker Memorial Lecturer: Douglas M. Stocco, Ph.D. Molecular and cellular endocrinology 2016. PMID: 27345241


  26. Tee MK, Speek M, Legeza B, Modi B, Teves ME, McAllister JM, Strauss JF, Miller WL. Alternative splicing of DENND1A, a PCOS candidate gene, generates variant 2. Molecular and cellular endocrinology 2016. PMID: 27297658


  27. Miller WL. Genetic disorders of Vitamin D biosynthesis and degradation. The Journal of steroid biochemistry and molecular biology 2016. PMID: 27060335


  28. Else T, Auchus RJ, Miller WL. Adrenocortical carcinoma in a 17th-century girl. The Journal of steroid biochemistry and molecular biology 2016. PMID: 26960202


  29. Miller WL. Disorders in the initial steps of steroid hormone synthesis. The Journal of steroid biochemistry and molecular biology 2016. PMID: 26960203


  30. Miller WL, Chung BC. The First Defect in Electron Transfer to Mitochondrial P450 Enzymes. Endocrinology 2016. PMID: 26919515


  31. Jin Y, Chen M, Penning TM, Miller WL. Electron transfer by human wild-type and A287P mutant P450 oxidoreductase assessed by transient kinetics: functional basis of P450 oxidoreductase deficiency. The Biochemical journal 2015. PMID: 25728647


  32. Delle Piane L, Rinaudo PF, Miller WL. 150 years of congenital adrenal hyperplasia: translation and commentary of De Crecchio's classic paper from 1865. Endocrinology 2015. PMID: 25635623


  33. Miller WL. Fetal endocrine therapy for congenital adrenal hyperplasia should not be done. Best practice & research. Clinical endocrinology & metabolism 2015. PMID: 26051303


  34. Agrawal V, Tee MK, Qiao J, Muench MO, Miller WL. Potential role of increased oxygenation in altering perinatal adrenal steroidogenesis. Pediatric research 2014. PMID: 25470028


  35. Mugg A, Legeza B, Tee MK, Damm I, Long RK, Miller WL. Quantitation of CYP24A1 enzymatic activity with a simple two-hybrid system. The Journal of clinical endocrinology and metabolism 2014. PMID: 25375986


  36. Miller WL, Tee MK. The post-translational regulation of 17,20 lyase activity. Molecular and cellular endocrinology 2014. PMID: 25224484


  37. Chanakul A, Zhang MY, Louw A, Armbrecht HJ, Miller WL, Portale AA, Perwad F. FGF-23 regulates CYP27B1 transcription in the kidney and in extra-renal tissues. PloS one 2013. PMID: 24019880


  38. Taylor LK, Auchus RJ, Baskin LS, Miller WL. Cortisol response to operative stress with anesthesia in healthy children. The Journal of clinical endocrinology and metabolism 2013. PMID: 23861461


  39. Tee MK, Miller WL. Phosphorylation of human cytochrome P450c17 by p38a selectively increases 17,20 lyase activity and androgen biosynthesis. The Journal of biological chemistry 2013. PMID: 23836902


  40. Miller WL. Steroid hormone synthesis in mitochondria. Molecular and cellular endocrinology 2013. PMID: 23628605


  41. Biason-Lauber A, Miller WL, Pandey AV, Flück CE. Of marsupials and men: "Backdoor" dihydrotestosterone synthesis in male sexual differentiation. Molecular and cellular endocrinology 2013. PMID: 23376007


  42. Tee MK, Abramsohn M, Loewenthal N, Harris M, Siwach S, Kaplinsky A, Markus B, Birk O, Sheffield VC, Parvari R, Pavari R, Hershkovitz E, Miller WL. Varied clinical presentations of seven patients with mutations in CYP11A1 encoding the cholesterol side-chain cleavage enzyme, P450scc. The Journal of clinical endocrinology and metabolism 2013. PMID: 23337730


  43. Nebert DW, Wikvall K, Miller WL. Human cytochromes P450 in health and disease. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2013. PMID: 23297354


  44. Agrawal V, Miller WL. P450 oxidoreductase: genotyping, expression, purification of recombinant protein, and activity assessments of wild-type and mutant protein. Methods in molecular biology (Clifton, N.J.) 2013. PMID: 23475681


  45. Gucev ZS, Tee MK, Chitayat D, Wherrett DK, Miller WL. Distinguishing deficiencies in the steroidogenic acute regulatory protein and the cholesterol side chain cleavage enzyme causing neonatal adrenal failure. The Journal of pediatrics 2012. PMID: 23158025


  46. Miller WL, Witchel SF. Prenatal treatment of congenital adrenal hyperplasia: risks outweigh benefits. American journal of obstetrics and gynecology 2012. PMID: 23123167


  47. Miller WL. A brief history of adrenal research: steroidogenesis - the soul of the adrenal. Molecular and cellular endocrinology 2012. PMID: 23123735


  48. Miller WL. P450 oxidoreductase deficiency: a disorder of steroidogenesis with multiple clinical manifestations. Science signaling 2012. PMID: 23092891


  49. Auchus RJ, Miller WL. Defects in androgen biosynthesis causing 46,XY disorders of sexual development. Seminars in reproductive medicine 2012. PMID: 23044879


  50. Subramanian M, Agrawal V, Sandee D, Tam HK, Miller WL, Tracy TS. Effect of P450 oxidoreductase variants on the metabolism of model substrates mediated by CYP2C9.1, CYP2C9.2, and CYP2C9.3. Pharmacogenetics and genomics 2012. PMID: 22547083


  51. Papadopoulos V, Miller WL. Role of mitochondria in steroidogenesis. Best practice & research. Clinical endocrinology & metabolism 2012. PMID: 23168279


  52. Witchel SF, Miller WL. Prenatal treatment of congenital adrenal hyperplasia-not standard of care. Journal of genetic counseling 2012. PMID: 22639328


  53. Schonemann MD, Muench MO, Tee MK, Miller WL, Mellon SH. Expression of P450c17 in the human fetal nervous system. Endocrinology 2012. PMID: 22434081


  54. Auchus RJ, Miller WL. Congenital adrenal hyperplasia--more dogma bites the dust. The Journal of clinical endocrinology and metabolism 2012. PMID: 22392955


  55. Miller WL. The syndrome of 17,20 lyase deficiency. The Journal of clinical endocrinology and metabolism 2011. PMID: 22072737


  56. Miller WL, Bose HS. Early steps in steroidogenesis: intracellular cholesterol trafficking. Journal of lipid research 2011. PMID: 21976778


  57. Flück CE, Meyer-Böni M, Pandey AV, Kempná P, Miller WL, Schoenle EJ, Biason-Lauber A. Why boys will be boys: two pathways of fetal testicular androgen biosynthesis are needed for male sexual differentiation. American journal of human genetics 2011. PMID: 21802064


  58. Sandee D, Miller WL. High-yield expression of a catalytically active membrane-bound protein: human P450 oxidoreductase. Endocrinology 2011. PMID: 21586563


  59. Tee MK, Huang N, Damm I, Miller WL. Transcriptional regulation of the human P450 oxidoreductase gene: hormonal regulation and influence of promoter polymorphisms. Molecular endocrinology (Baltimore, Md.) 2011. PMID: 21393444


  60. Auchus RJ, Witchel SF, Leight KR, Aisenberg J, Azziz R, Bachega TA, Baker LA, Baratz AB, Baskin LS, Berenbaum SA, Breault DT, Cerame BI, Conway GS, Eugster EA, Fracassa S, Gearhart JP, Geffner ME, Harris KB, Hurwitz RS, Katz AL, Kalro BN, Lee PA, Alger Lin G, Loechner KJ, Marshall I, Merke DP, Migeon CJ, Miller WL, Nenadovich TL, Oberfield SE, Pass KA, Poppas DP, Lloyd-Puryear MA, Quigley CA, Riepe FG, Rink RC, Rivkees SA, Sandberg DE, Schaeffer TL, Schlussel RN, Schneck FX, Seely EW, Snyder D, Speiser PW, Therrell BL, Vanryzin C, Vogiatzi MG, Wajnrajch MP, White PC, Zuckerman AE. Guidelines for the Development of Comprehensive Care Centers for Congenital Adrenal Hyperplasia: Guidance from the CARES Foundation Initiative. International journal of pediatric endocrinology 2011. PMID: 21274448


  61. Miller WL. Role of mitochondria in steroidogenesis. Endocrine development 2010. PMID: 21164254


  62. Sahakitrungruang T, Tee MK, Blackett PR, Miller WL. Partial defect in the cholesterol side-chain cleavage enzyme P450scc (CYP11A1) resembling nonclassic congenital lipoid adrenal hyperplasia. The Journal of clinical endocrinology and metabolism 2010. PMID: 21159840


  63. Ghayee HK, Rege J, Watumull LM, Nwariaku FE, Carrick KS, Rainey WE, Miller WL, Auchus RJ. Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new syndrome. The Journal of clinical endocrinology and metabolism 2010. PMID: 21084398


  64. Miller WL, Agrawal V, Sandee D, Tee MK, Huang N, Choi JH, Morrissey K, Giacomini KM. Consequences of POR mutations and polymorphisms. Molecular and cellular endocrinology 2010. PMID: 21070833


  65. Miller WL, Auchus RJ. The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders. Endocrine reviews 2010. PMID: 21051590


  66. Sandee D, Morrissey K, Agrawal V, Tam HK, Kramer MA, Tracy TS, Giacomini KM, Miller WL. Effects of genetic variants of human P450 oxidoreductase on catalysis by CYP2D6 in vitro. Pharmacogenetics and genomics 2010. PMID: 20940534


  67. Agrawal V, Choi JH, Giacomini KM, Miller WL. Substrate-specific modulation of CYP3A4 activity by genetic variants of cytochrome P450 oxidoreductase. Pharmacogenetics and genomics 2010. PMID: 20697309


  68. Speiser PW, Azziz R, Baskin LS, Ghizzoni L, Hensle TW, Merke DP, Meyer-Bahlburg HF, Miller WL, Montori VM, Oberfield SE, Ritzen M, White PC, Endocrine Society. Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline. The Journal of clinical endocrinology and metabolism 2010. PMID: 20823466


  69. Dong Q, Cheng Z, Chang W, Blackman BE, Conte FA, Hu J, Shoback D, Miller WL. Naturally-occurring mutation in the calcium-sensing receptor reveals the significance of extracellular domain loop III region for class C G-protein-coupled receptor function. The Journal of clinical endocrinology and metabolism 2010. PMID: 20631026


  70. Speiser PW, Azziz R, Baskin LS, Ghizzoni L, Hensle TW, Merke DP, Meyer-Bahlburg HF, Miller WL, Montori VM, Oberfield SE, Ritzen M, White PC. A Summary of the Endocrine Society Clinical Practice Guidelines on Congenital Adrenal Hyperplasia due to Steroid 21-Hydroxylase Deficiency. International journal of pediatric endocrinology 2010. PMID: 20981249


  71. Sahakitrungruang T, Soccio RE, Lang-Muritano M, Walker JM, Achermann JC, Miller WL. Clinical, genetic, and functional characterization of four patients carrying partial loss-of-function mutations in the steroidogenic acute regulatory protein (StAR). The Journal of clinical endocrinology and metabolism 2010. PMID: 20444910


  72. Sahakitrungruang T, Tee MK, Rattanachartnarong N, Shotelersuk V, Suphapeetiporn K, Miller WL. Functional characterization of vasopressin receptor 2 mutations causing partial and complete congenital nephrogenic diabetes insipidus in Thai families. Hormone research in paediatrics 2010. PMID: 20389105


  73. Wang YH, Tee MK, Miller WL. Human cytochrome p450c17: single step purification and phosphorylation of serine 258 by protein kinase a. Endocrinology 2010. PMID: 20160131


  74. Miller WL. Did Akhenaten have the Antley-Bixler syndrome? Annals of internal medicine 2009. PMID: 20008767


  75. Sahakitrungruang T, Huang N, Tee MK, Agrawal V, Russell WE, Crock P, Murphy N, Migeon CJ, Miller WL. Clinical, genetic, and enzymatic characterization of P450 oxidoreductase deficiency in four patients. The Journal of clinical endocrinology and metabolism 2009. PMID: 19837910


  76. Sim SC, Miller WL, Zhong XB, Arlt W, Ogata T, Ding X, Wolf CR, Flück CE, Pandey AV, Henderson CJ, Porter TD, Daly AK, Nebert DW, Ingelman-Sundberg M. Nomenclature for alleles of the cytochrome P450 oxidoreductase gene. Pharmacogenetics and genomics 2009. PMID: 19535965


  77. Sahakitrungruang T, Tee MK, Speiser PW, Miller WL. Novel P450c17 mutation H373D causing combined 17alpha-hydroxylase/17,20-lyase deficiency. The Journal of clinical endocrinology and metabolism 2009. PMID: 19470621


  78. Miller WL. Androgen synthesis in adrenarche. Reviews in endocrine & metabolic disorders 2009. PMID: 18821018


  79. Ranadive SA, Ersoy B, Favre H, Cheung CC, Rosenthal SM, Miller WL, Vaisse C. Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus. Clinical endocrinology 2008. PMID: 19170711


  80. Gomes LG, Huang N, Agrawal V, Mendonça BB, Bachega TA, Miller WL. Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency. The Journal of clinical endocrinology and metabolism 2008. PMID: 18957504


  81. Miller WL, Huang N, Agrawal V, Giacomini KM. Genetic variation in human P450 oxidoreductase. Molecular and cellular endocrinology 2008. PMID: 18930113


  82. Agrawal V, Huang N, Miller WL. Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19. Pharmacogenetics and genomics 2008. PMID: 18551037


  83. Hershkovitz E, Parvari R, Wudy SA, Hartmann MF, Gomes LG, Loewental N, Miller WL. Homozygous mutation G539R in the gene for P450 oxidoreductase in a family previously diagnosed as having 17,20-lyase deficiency. The Journal of clinical endocrinology and metabolism 2008. PMID: 18559916


  84. Bremer AA, Miller WL. The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism for hyperandrogenemia and insulin resistance. Fertility and sterility 2008. PMID: 18433749


  85. Gomes LG, Huang N, Agrawal V, Mendonça BB, Bachega TA, Miller WL. The common P450 oxidoreductase variant A503V is not a modifier gene for 21-hydroxylase deficiency. The Journal of clinical endocrinology and metabolism 2008. PMID: 18397975


  86. Scott RR, Miller WL. Genetic and clinical features of p450 oxidoreductase deficiency. Hormone research 2008. PMID: 18259105


  87. Bose M, Whittal RM, Miller WL, Bose HS. Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein. The Journal of biological chemistry 2008. PMID: 18250166


  88. Huang N, Agrawal V, Giacomini KM, Miller WL. Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations. Proceedings of the National Academy of Sciences of the United States of America 2008. PMID: 18230729


  89. Bose HS, Whittal RM, Ran Y, Bose M, Baker BY, Miller WL. StAR-like activity and molten globule behavior of StARD6, a male germ-line protein. Biochemistry 2008. PMID: 18211099


  90. Tee MK, Dong Q, Miller WL. Pathways leading to phosphorylation of p450c17 and to the posttranslational regulation of androgen biosynthesis. Endocrinology 2008. PMID: 18187541


  91. Kim CJ, Lin L, Huang N, Quigley CA, AvRuskin TW, Achermann JC, Miller WL. Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc. The Journal of clinical endocrinology and metabolism 2008. PMID: 18182448


  92. Flück CE, Pandey AV, Huang N, Agrawal V, Miller WL. P450 oxidoreductase deficiency - a new form of congenital adrenal hyperplasia. Endocrine development 2008. PMID: 18493134


  93. Miller WL. Steroidogenic enzymes. Endocrine development 2008. PMID: 18493130


  94. Kim CJ, Kaplan LE, Perwad F, Huang N, Sharma A, Choi Y, Miller WL, Portale AA. Vitamin D 1alpha-hydroxylase gene mutations in patients with 1alpha-hydroxylase deficiency. The Journal of clinical endocrinology and metabolism 2007. PMID: 17488797


  95. Scott RR, Gomes LG, Huang N, Van Vliet G, Miller WL. Apparent manifesting heterozygosity in P450 oxidoreductase deficiency and its effect on coexisting 21-hydroxylase deficiency. The Journal of clinical endocrinology and metabolism 2007. PMID: 17389698


  96. Miller WL. Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter. Biochimica et biophysica acta 2007. PMID: 17433772


  97. Baker BY, Epand RF, Epand RM, Miller WL. Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR. The Journal of biological chemistry 2007. PMID: 17301050


  98. Miller WL. Mechanism of StAR's regulation of mitochondrial cholesterol import. Molecular and cellular endocrinology 2007. PMID: 17207924


  99. Miller WL. StAR search--what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import. Molecular endocrinology (Baltimore, Md.) 2006. PMID: 16973755


  100. Baker BY, Lin L, Kim CJ, Raza J, Smith CP, Miller WL, Achermann JC. Nonclassic congenital lipoid adrenal hyperplasia: a new disorder of the steroidogenic acute regulatory protein with very late presentation and normal male genitalia. The Journal of clinical endocrinology and metabolism 2006. PMID: 16968793


  101. Flück CE, Miller WL. P450 oxidoreductase deficiency: a new form of congenital adrenal hyperplasia. Current opinion in pediatrics 2006. PMID: 16915000


  102. Miller WL, Huang N, Pandey AV, Flück CE, Agrawal V. P450 oxidoreductase deficiency: a new disorder of steroidogenesis. Annals of the New York Academy of Sciences 2005. PMID: 16467261


  103. Baker BY, Yaworsky DC, Miller WL. A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR. The Journal of biological chemistry 2005. PMID: 16234239


  104. Feldman BJ, Rosenthal SM, Vargas GA, Fenwick RG, Huang EA, Matsuda-Abedini M, Lustig RH, Mathias RS, Portale AA, Miller WL, Gitelman SE. Nephrogenic syndrome of inappropriate antidiuresis. The New England journal of medicine 2005. PMID: 15872203


  105. Huang N, Dardis A, Miller WL. Regulation of cytochrome b5 gene transcription by Sp3, GATA-6, and steroidogenic factor 1 in human adrenal NCI-H295A cells. Molecular endocrinology (Baltimore, Md.) 2005. PMID: 15831526


  106. Huang N, Pandey AV, Agrawal V, Reardon W, Lapunzina PD, Mowat D, Jabs EW, Van Vliet G, Sack J, Flück CE, Miller WL. Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis. American journal of human genetics 2005. PMID: 15793702


  107. Miller WL. Minireview: regulation of steroidogenesis by electron transfer. Endocrinology 2005. PMID: 15774560


  108. Flück CE, Yaworsky DC, Miller WL. Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2. Epilepsia 2005. PMID: 15730543


  109. Pandey AV, Miller WL. Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17. The Journal of biological chemistry 2005. PMID: 15687493


  110. Miller WL. Disorders of androgen synthesis--from cholesterol to dehydroepiandrosterone. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2005. PMID: 16103714


  111. Chen X, Baker BY, Abduljabbar MA, Miller WL. A genetic isolate of congenital lipoid adrenal hyperplasia with atypical clinical findings. The Journal of clinical endocrinology and metabolism 2004. PMID: 15546900


  112. Miller WL, Huang N, Flück CE, Pandey AV. P450 oxidoreductase deficiency. Lancet (London, England) 2004. PMID: 15530620


  113. Pandey AV, Flück CE, Huang N, Tajima T, Fujieda K, Miller WL. P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes. Endocrine research 2004. PMID: 15666840


  114. Hauet T, Yao ZX, Bose HS, Wall CT, Han Z, Li W, Hales DB, Miller WL, Culty M, Papadopoulos V. Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria. Molecular endocrinology (Baltimore, Md.) 2004. PMID: 15498831


  115. Yaworsky DC, Baker BY, Bose HS, Best KB, Jensen LB, Bell JD, Baldwin MA, Miller WL. pH-dependent Interactions of the carboxyl-terminal helix of steroidogenic acute regulatory protein with synthetic membranes. The Journal of biological chemistry 2004. PMID: 15489236


  116. Huang N, Miller WL. LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells. Molecular endocrinology (Baltimore, Md.) 2004. PMID: 15471945


  117. Miller WL. P450 oxidoreductase deficiency: a new disorder of steroidogenesis with multiple clinical manifestations. Trends in endocrinology and metabolism: TEM 2004. PMID: 15350602


  118. Dong Q, Miller WL. Vitamin D 25-hydroxylase deficiency. Molecular genetics and metabolism 2004. PMID: 15464435


  119. Gassner HL, Toppari J, Quinteiro González S, Miller WL. Near-miss apparent SIDS from adrenal crisis. The Journal of pediatrics 2004. PMID: 15289763


  120. Holmes NM, Miller WL, Baskin LS. Lack of defects in androgen production in children with hypospadias. The Journal of clinical endocrinology and metabolism 2004. PMID: 15181062


  121. Arlt W, Neogi P, Gross C, Miller WL. Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of PPARgamma agonist activity. Journal of molecular endocrinology 2004. PMID: 15072549


  122. Flück CE, Miller WL. GATA-4 and GATA-6 modulate tissue-specific transcription of the human gene for P450c17 by direct interaction with Sp1. Molecular endocrinology (Baltimore, Md.) 2004. PMID: 14988427


  123. Flück CE, Tajima T, Pandey AV, Arlt W, Okuhara K, Verge CF, Jabs EW, Mendonça BB, Fujieda K, Miller WL. Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome. Nature genetics 2004. PMID: 14758361


  124. Tuckey RC, Bose HS, Czerwionka I, Miller WL. Molten globule structure and steroidogenic activity of N-218 MLN64 in human placental mitochondria. Endocrinology 2004. PMID: 14715710


  125. Miller WL. Steroid 17alpha-hydroxylase deficiency--not rare everywhere. The Journal of clinical endocrinology and metabolism 2004. PMID: 14715825


  126. Lin CJ, Dardis A, Wijesuriya SD, Abdullah MA, Casella SJ, Miller WL. Lack of mutations in CYP2D6 and CYP27 in patients with apparent deficiency of vitamin D 25-hydroxylase. Molecular genetics and metabolism 2003. PMID: 14654361


  127. Dardis A, Miller WL. Dexamethasone does not exert direct intracellular feedback on steroidogenesis in human adrenal NCI-H295A cells. The Journal of endocrinology 2003. PMID: 14529573


  128. Flück CE, Miller WL, Auchus RJ. The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway. The Journal of clinical endocrinology and metabolism 2003. PMID: 12915666


  129. Nazarov PA, Drutsa VL, Miller WL, Shkumatov VM, Luzikov VN, Novikova LA. Formation and functioning of fused cholesterol side-chain cleavage enzymes. DNA and cell biology 2003. PMID: 12823901


  130. Rao RM, Jo Y, Leers-Sucheta S, Bose HS, Miller WL, Azhar S, Stocco DM. Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport. Biology of reproduction 2003. PMID: 12493702


  131. Miller WL, Portale AA. Vitamin D biosynthesis and vitamin D 1 alpha-hydroxylase deficiency. Endocrine development 2003. PMID: 12964431


  132. Miller WL. Androgen biosynthesis from cholesterol to DHEA. Molecular and cellular endocrinology 2002. PMID: 12573809


  133. Arlt W, Martens JW, Song M, Wang JT, Auchus RJ, Miller WL. Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species. Endocrinology 2002. PMID: 12446594


  134. Pandey AV, Mellon SH, Miller WL. Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17. The Journal of biological chemistry 2002. PMID: 12444089


  135. Bose HS, Lingappa VR, Miller WL. The steroidogenic acute regulatory protein, StAR, works only at the outer mitochondrial membrane. Endocrine research 2002. PMID: 12530629


  136. Tuckey RC, Headlam MJ, Bose HS, Miller WL. Transfer of cholesterol between phospholipid vesicles mediated by the steroidogenic acute regulatory protein (StAR). The Journal of biological chemistry 2002. PMID: 12372832


  137. Wijesuriya SD, Bristow J, Miller WL. Localization and analysis of the principal promoter for human tenascin-X. Genomics 2002. PMID: 12376099


  138. Flück CE, Martens JW, Conte FA, Miller WL. Clinical, genetic, and functional characterization of adrenocorticotropin receptor mutations using a novel receptor assay. The Journal of clinical endocrinology and metabolism 2002. PMID: 12213892


  139. Miller WL. Disorders of androgen biosynthesis. Seminars in reproductive medicine 2002. PMID: 12428201


  140. Wang X, Zhang MY, Miller WL, Portale AA. Novel gene mutations in patients with 1alpha-hydroxylase deficiency that confer partial enzyme activity in vitro. The Journal of clinical endocrinology and metabolism 2002. PMID: 12050193


  141. Bose HS, Lingappa VR, Miller WL. Rapid regulation of steroidogenesis by mitochondrial protein import. Nature 2002. PMID: 11986670


  142. Xie Z, Munson SJ, Huang N, Portale AA, Miller WL, Bikle DD. The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes. The Journal of biological chemistry 2002. PMID: 11956203


  143. Zhang MY, Wang X, Wang JT, Compagnone NA, Mellon SH, Olson JL, Tenenhouse HS, Miller WL, Portale AA. Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1alpha-hydroxylase gene expression in the proximal renal tubule. Endocrinology 2002. PMID: 11796514


  144. Clayton PE, Miller WL, Oberfield SE, Ritzén EM, Sippell WG, Speiser PW, ESPE/ LWPES CAH Working Group. Consensus statement on 21-hydroxylase deficiency from the European Society for Paediatric Endocrinology and the Lawson Wilkins Pediatric Endocrine Society. Hormone research 2002. PMID: 12324718