James Padbury, MD

As a senior neonatologist, I have participated consistently in independent research, leadership, administration and management at each of the of my academic appointments. This has included executive committee service, financial leadership and oversight, and service on search committees.
Education
Fellowship, 1981 - Neonatal-Perinatal Medicine, Harbor - UCLA Medical Center
Chief Resident, 1977 - Pediatrics, University of California San Francisco
Residency, 1976 - Pediatrics, Boston Children's Hospital Medical Center
Fellowship, 1975 - Neonatal-Perinatal Medicine, Boston Children's Hospital Medical Center
Internship, 1974 - Pediatrics, University of California San Francisco
MD, 1973 - Medicine, University of California Los Angeles
BS, 1969 - Biological Science, University of California Irvine
Honors and Awards
  • Certificate of National Research Mentor, National Research Mentoring Network, 2019
  • Editorial Board Certificate of Excellence, Journal of Pediatrics, 2018
  • Mentor of the Year, Eastern Society for Pediatric Research, 2014
  • Volunteer of the Year Award, March of Dimes Rhode Island Chapter, 2009
  • National Distinguished Volunteer Service Award, National Foundation March of Dime, 2008
  • Jonas Salk Health Leadership Award for Healthcare Providers, March of Dimes Rhode Island Chapter, 2004
  • Medical Staff Distinguished Service Award, Women & Infants Hospital of RI, 2004
  • Basil O’Connor Research Scholar Award, National Foundation March of Dimes, 1984
  • Richard E. Weitzman, M.D. Memorial Endocrinology Research Award, Harbor - UCLA Medical Center, 1981
  • Magna Cum Laude, University of California Irvine, 1969

  1. Huang Z, Cheng S, Jash S, Fierce J, Agudelo A, Higashiyama T, Hanna N, Nakashima A, Saito S, Padbury J, Schuster J, Sharma S. Exploiting sweet relief for preeclampsia by targeting autophagy-lysosomal machinery and proteinopathy. Experimental & molecular medicine 2024. PMID: 38760513


  2. Schliep KC, Shaaban CE, Meeks H, Fraser A, Smith KR, Majersik JJ, Foster NL, Wactawski-Wende J, Østbye T, Tschanz J, Padbury JF, Sharma S, Zhang Y, Facelli JC, Abdelrahman CS, Theilen L, Varner MW. Hypertensive disorders of pregnancy and subsequent risk of Alzheimer's disease and other dementias. Alzheimer's & dementia (Amsterdam, Netherlands) 2023. PMID: 37223334


  3. Padbury J. Febrile preemies in the ED. The Journal of pediatrics 2023. PMID: 36521970


  4. Garg PM, Paschal JL, Zhang M, Pippins M, Taylor C, Sanderson K, Reddy K, Askenazi D, Padbury JF, Hillegass WB. Clinical impact of severe acute kidney injury on post-operative and brain injury outcomes in preterm infants following surgical necrotizing enterocolitis. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022. PMID: 36093832


  5. Kimberly JA, Fede J, Kogut S, Stranieri G, Hayward AR, Stevenson JF, Padbury J. Evaluating systemic changes to support clinical and translational health research. Evaluation and Program Planning 2022. PMID: 35973392


  6. Schuster J, Tollefson GA, Zarate V, Agudelo A, Stabila J, Ragavendran A, Padbury J, Uzun A. Protein Network Analysis of Whole Exome Sequencing of Severe Preeclampsia. Frontiers in genetics 2022. PMID: 35719905


  7. Berglund-Brown I, Nissen E, Koestler DC, Butler RA, Eliot MN, Padbury JF, Salas LA, Molinaro AM, Christensen BC, Wiencke JK, Kelsey KT. A core of differentially methylated CpG loci in gMDSCs isolated from neonatal and adult sources. Clinical epigenetics 2022. PMID: 35189960


  8. Uzun A, Schuster JS, Stabila J, Zarate V, Tollefson GA, Agudelo A, Kothiyal P, Wong WSW, Padbury J. Protein interaction networks define the genetic architecture of preterm birth. Scientific Reports 2022. PMID: 35013336


  9. Camerota M, Davis JM, Dansereau LM, Oliveira EL, Padbury JF, Lester BM. Effects of Pharmacologic Treatment for Neonatal Abstinence Syndrome on DNA Methylation and Neurobehavior: A Prospective Cohort Study. The Journal of pediatrics 2021. PMID: 34971656


  10. Graw S, Camerota M, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, DellaGrotta SA, Dansereau LM, Padbury JF, O'Shea M, Lester BM, Marsit CJ, Everson TM. NEOage clocks - epigenetic clocks to estimate post-menstrual and postnatal age in preterm infants. Aging 2021. PMID: 34655469


  11. Cheng S, Banerjee S, Daiello LA, Nakashima A, Jash S, Huang Z, Drake JD, Ernerudh J, Berg G, Padbury J, Saito S, Ott BR, Sharma S. Novel blood test for early biomarkers of preeclampsia and Alzheimer's disease. Scientific Reports 2021. PMID: 34354200


  12. Cay G, Ravichandran V, Saikia MJ, Hoffman L, Laptook A, Padbury J, Salisbury AL, Gitelson-Kahn A, Venkatasubramanian K, Shahriari Y, Mankodiya K. An E-Textile Respiration Sensing System for NICU Monitoring: Design and Validation. Journal of signal processing systems 2021. PMID: 34306304


  13. Boudreau LE, Padbury JF. 50 Years Ago in TheJournalofPediatrics: An Ongoing Feat: Assessing Proper Endotracheal Tube Position in the Neonate. The Journal of pediatrics 2021. PMID: 34030842


  14. Padbury JF, Do BT, Bann CM, Marsit C, Hintz SR, Vohr BR, Lowe J, Newman JE, Granger DA, Payne A, Watterberg K, SUPPORT Study Group of the Eunice Kennedy Shriver National Institute of Child Health and Human Devel. DNA methylation in former extremely low birth weight newborns: association with cardiovascular and endocrine function. Pediatric research 2021. PMID: 33953357


  15. Zabala V, Stranieri G, Fournier H, Hawrot E, Padbury J. Advance-CTR: Statewide Infrastructure to Improve Health in Rhode Island through Clinical and Translational Research. Rhode Island medical journal (2013) 2021. PMID: 33789408


  16. Padbury JF, Cho BP. Translational Research: The Time is Now. Rhode Island medical journal (2013) 2021. PMID: 33789402


  17. Boudreau LE, Padbury JF. 50 Years Ago in TheJournalofPediatrics: Diazoxide-Induced Hyperosmolar Nonketotic Coma: Contemporary Genetic Insights. The Journal of pediatrics 2021. PMID: 33632397


  18. Cho B, Padbury J. Impact of NIH's Institutional Development Award (IDeA) Programs in Rhode Island. Rhode Island medical journal (2013) 2021. PMID: 33648314


  19. Fede J, Kogut SJ, Hayward A, Stevenson JF, Willey-Temkin C, Fournier H, Stranieri G, Kimberly JA, Padbury J. Improving the quality and quantity of clinical and translational research statewide: An application of group concept mapping. Journal of Clinical and Translational Science 2021. PMID: 33948289


  20. Everson TM, O'Shea TM, Burt A, Hermetz K, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, Soliman A, DellaGrotta SA, Dansereau LM, Padbury JF, Lester BM, Marsit CJ. Serious neonatal morbidities are associated with differences in DNA methylation among very preterm infants. Clinical epigenetics 2020. PMID: 33076993


  21. Aghagoli G, Sheinkopf SJ, Everson TM, Marsit CJ, Lee H, Burt AA, Carter BS, Helderman JB, Hofheimer JA, McGowan EC, Neal CR, O'Shea TM, Pastyrnak SL, Smith LM, Soliman A, Dansereau LM, DellaGrotta SA, Padbury JF, Lester BM. Epigenome-wide analysis identifies genes and pathways linked to acoustic cry variation in preterm infants. Pediatric research 2020. PMID: 32967004


  22. Mercer JS, Erickson-Owens DA, Deoni SCL, Dean Iii DC, Tucker R, Parker AB, Joelson S, Mercer EN, Collins J, Padbury JF. The Effects of Delayed Cord Clamping on 12-Month Brain Myelin Content and Neurodevelopment: A Randomized Controlled Trial. American journal of perinatology 2020. PMID: 32702760


  23. Armanious D, Schuster J, Tollefson GA, Agudelo A, DeWan AT, Istrail S, Padbury J, Uzun A. Proteinarium: Multi-sample protein-protein interaction analysis and visualization tool. Genomics 2020. PMID: 32702417


  24. Schuster J, Cheng SB, Padbury J, Sharma S. Placental extracellular vesicles and pre-eclampsia. American journal of reproductive immunology (New York, N.Y. : 1989) 2020. PMID: 32619308


  25. Oni-Orisan OO, Dansereau LM, Marsit CJ, Smith LM, Neal CR, Della Grotta SA, Padbury JF, Lester BM. DNA methylation in children with prenatal methamphetamine exposure and environmental adversity. Pediatric research 2020. PMID: 32663835


  26. Padbury JF. Get the most out of your data. The Journal of pediatrics 2020. PMID: 32089173


  27. Aghagoli G, Conradt E, Padbury JF, Sheinkopf SJ, Tokadjian H, Dansereau LM, Tronick EZ, Marsit CJ, Lester BM. Social Stress-Related Epigenetic Changes Associated With Increased Heart Rate Variability in Infants. Frontiers in behavioral neuroscience 2020. PMID: 32009914


  28. Nakashima A, Cheng SB, Ikawa M, Yoshimori T, Huber WJ, Menon R, Huang Z, Fierce J, Padbury JF, Sadovsky Y, Saito S, Sharma S. Evidence for lysosomal biogenesis proteome defect and impaired autophagy in preeclampsia. Autophagy 2019. PMID: 31856641


  29. Padbury JF. How old am I really? The Journal of pediatrics 2019. PMID: 31761132


  30. Tollefson GA, Schuster J, Gelin F, Agudelo A, Ragavendran A, Restrepo I, Stey P, Padbury J, Uzun A. VIVA (VIsualization of VAriants): A VCF File Visualization Tool. Scientific Reports 2019. PMID: 31477778


  31. Schuster J, Uzun A, Stablia J, Schorl C, Mori M, Padbury JF. Effect of prematurity on genome wide methylation in the placenta. BMC medical genetics 2019. PMID: 31253109


  32. Gupta A, Sanville J, Menz T, Warner N, Muise AM, Fiedler K, Martín MG, Padbury J, Phornphutkul C, Sanchez-Esteban J, Cerezo CS. Application of Whole Exome Sequencing in Congenital Secretory Diarrhea Diagnosis. Journal of pediatric gastroenterology and nutrition 2019. PMID: 30633106


  33. Everson TM, Marsit CJ, Michael O'Shea T, Burt A, Hermetz K, Carter BS, Helderman J, Hofheimer JA, McGowan EC, Neal CR, Pastyrnak SL, Smith LM, Soliman A, DellaGrotta SA, Dansereau LM, Padbury JF, Lester BM. Epigenome-wide Analysis Identifies Genes and Pathways Linked to Neurobehavioral Variation in Preterm Infants. Scientific Reports 2019. PMID: 31004082


  34. Padbury JF. Genetic disorders of lung development. The Journal of pediatrics 2019. PMID: 30798833


  35. Phornphutkul C, Padbury J. Large Scale Next Generation Sequencing and Newborn Screening: Are We Ready? The Journal of pediatrics 2019. PMID: 30819502


  36. Padbury JF. Doc, my tummy hurts. The Journal of pediatrics 2019. PMID: 30684984


  37. Schuster J, Superdock M, Agudelo A, Stey P, Padbury J, Sarkar IN, Uzun A. Machine learning approach to literature mining for the genetics of complex diseases. Database : the journal of biological databases and curation 2019. PMID: 31768545


  38. Padbury JF. Turning a negative into a positive. The Journal of pediatrics 2018. PMID: 30470375


  39. Lester BM, Conradt E, LaGasse LL, Tronick EZ, Padbury JF, Marsit CJ. Epigenetic Programming by Maternal Behavior in the Human Infant. Pediatrics 2018. PMID: 30257918


  40. Sprinz P, Lemke K, Padbury J, Farrow C. Newborn Screening for Hemoglobinopathies in Rhode Island, 2017. Rhode Island medical journal (2013) 2018. PMID: 30189698


  41. Shah BA, Padbury JF, Anderson MP, Holick MF, Szyld E, Gordon CM. Vitamin D and associated perinatal-neonatal outcomes among extremely low-birth-weight infants. Journal of perinatology : official journal of the California Perinatal Association 2018. PMID: 30108343


  42. Alvira CM, Steinhorn RH, Balistreri WF, Fineman JR, Oishi PE, Padbury JF, Kinsella JP, Abman SH. Enhancing the Development and Retention of Physician-Scientists in Academic Pediatrics: Strategies for Success. The Journal of pediatrics 2018. PMID: 30055815


  43. Mercer JS, Erickson-Owens DA, Deoni SCL, Dean DC, Collins J, Parker AB, Wang M, Joelson S, Mercer EN, Padbury JF. Effects of Delayed Cord Clamping on 4-Month Ferritin Levels, Brain Myelin Content, and Neurodevelopment: A Randomized Controlled Trial. The Journal of pediatrics 2018. PMID: 30473033


  44. Gupta A, Padbury J. 50 Years Ago in The Journal of Pediatrics: Platelet Counts in Healthy Premature Infants. The Journal of pediatrics 2018. PMID: 29936958


  45. Wang M, Mercer JS, Padbury JF. Delayed Cord Clamping in Infants with Suspected Intrauterine Growth Restriction. The Journal of pediatrics 2018. PMID: 29954605


  46. Benny MKV, Padbury J. 50 Years Ago in The Journal of Pediatrics: Human Cell Culture: An Important Tool for the Diagnosis and Understanding of Disease. The Journal of pediatrics 2018. PMID: 29478495


  47. Willey C, Fede J, Stevenson J, Hayward A, Kogut S, Fournier H, Padbury J. Clinical and Translational Research in Rhode Island: Results of a Needs Assessment Survey. Rhode Island medical journal (2013) 2018. PMID: 29393306


  48. Padbury JF. Better beginnings. The Journal of pediatrics 2017. PMID: 29144265


  49. Bingham A, Padbury JF. 50 Years Ago in The Journal of Pediatrics: Cellular Growth of Human Placenta. The Journal of pediatrics 2017. PMID: 28843311


  50. Xu Y, Gray A, Hardie DG, Uzun A, Shaw S, Padbury J, Phornphutkul C, Tseng YT. A novel, de novo mutation in the PRKAG2 gene: infantile-onset phenotype and the signaling pathway involved. American journal of physiology. Heart and circulatory physiology 2017. PMID: 28550180


  51. Mills DR, Mao Q, Chu S, Falcon Girard K, Kraus M, Padbury JF, De Paepe ME. Effects of human umbilical cord blood mononuclear cells on respiratory system mechanics in a murine model of neonatal lung injury. Experimental lung research 2017. PMID: 28353351


  52. Patra A, Chen X, Sadowska GB, Zhang J, Lim YP, Padbury JF, Banks WA, Stonestreet BS. Neutralizing anti-interleukin-1β antibodies reduce ischemia-related interleukin-1β transport across the blood-brain barrier in fetal sheep. Neuroscience 2017. PMID: 28089577


  53. Mercer JS, Erickson-Owens DA, Collins J, Barcelos MO, Parker AB, Padbury JF. Effects of delayed cord clamping on residual placental blood volume, hemoglobin and bilirubin levels in term infants: a randomized controlled trial. Journal of perinatology : official journal of the California Perinatal Association 2016. PMID: 27929530


  54. Stroud LR, Papandonatos GD, Parade SH, Salisbury AL, Phipps MG, Lester BM, Padbury JF, Marsit CJ. Prenatal Major Depressive Disorder, Placenta Glucocorticoid and Serotonergic Signaling, and Infant Cortisol Response. Psychosomatic medicine 2016. PMID: 27763986


  55. Shah BA, Migliori A, Kurihara I, Sharma S, Lim YP, Padbury J. Blood Level of Inter-Alpha Inhibitor Proteins Distinguishes Necrotizing Enterocolitis From Spontaneous Intestinal Perforation. The Journal of pediatrics 2016. PMID: 27745748


  56. Padbury JF. Gasping for air. The Journal of pediatrics 2016. PMID: 27666072


  57. Giarraputo J, DeLoach J, Padbury J, Uzun A, Marsit C, Hawes K, Lester B. Medical morbidities and DNA methylation of NR3C1 in preterm infants. Pediatric research 2016. PMID: 27653086


  58. Padbury JF. Lymphocyte genetic diversity revealed by next generation sequencing. The Journal of pediatrics 2016. PMID: 27568246


  59. Lester BM, Salisbury AL, Hawes K, Dansereau LM, Bigsby R, Laptook A, Taub M, Lagasse LL, Vohr BR, Padbury JF. 18-Month Follow-Up of Infants Cared for in a Single-Family Room Neonatal Intensive Care Unit. The Journal of pediatrics 2016. PMID: 27470693


  60. Uzun A, Sahin Y, Schuster JS, Zheng X, Ryckman K, Feingold E, Padbury J. Structural and genomic variation in preterm birth. Pediatric research 2016. PMID: 27466897


  61. Uzun A, Schuster J, McGonnigal B, Schorl C, Dewan A, Padbury J. Targeted Sequencing and Meta-Analysis of Preterm Birth. PloS one 2016. PMID: 27163930


  62. Saunders AC, McGonnigal B, Uzun A, Padbury J. The developmental expression of the CDK inhibitor p57(kip2) (Cdkn1c) in the early mouse placenta. Molecular reproduction and development 2016. PMID: 26988311


  63. Mirza H, Ziegler J, Ford S, Padbury J, Tucker R, Laptook A. Temporal Profile of Early Pulmonary Hypertension in Preterm Infants. American journal of perinatology 2016. PMID: 27057770


  64. Appleton AA, Murphy MA, Koestler DC, Lesseur C, Paquette AG, Padbury JF, Lester BM, Marsit CJ. Prenatal Programming of Infant Neurobehaviour in a Healthy Population. Paediatric and perinatal epidemiology 2016. PMID: 27004434


  65. Chen X, Rivard L, Naqvi S, Nakada S, Padbury JF, Sanchez-Esteban J, Stopa EG, Lim YP, Stonestreet BS. Expression and localization of Inter-alpha Inhibitors in rodent brain. Neuroscience 2016. PMID: 26964679


  66. Uzun A, Triche EW, Schuster J, Dewan AT, Padbury JF. dbPEC: a comprehensive literature-based database for preeclampsia related genes and phenotypes. Database : the journal of biological databases and curation 2016. PMID: 26946289


  67. Stroud LR, Papandonatos GD, Salisbury AL, Phipps MG, Huestis MA, Niaura R, Padbury JF, Marsit CJ, Lester BM. Epigenetic Regulation of Placental NR3C1: Mechanism Underlying Prenatal Programming of Infant Neurobehavior by Maternal Smoking? Child development 2016. PMID: 26822442


  68. Lester BM, Marsit CJ, Giarraputo J, Hawes K, LaGasse LL, Padbury JF. Neurobehavior related to epigenetic differences in preterm infants. Epigenomics 2015. PMID: 26585459


  69. Mercer JS, Erickson-Owens DA, Vohr BR, Tucker RJ, Parker AB, Oh W, Padbury JF. Effects of Placental Transfusion on Neonatal and 18 Month Outcomes in Preterm Infants: A Randomized Controlled Trial. The Journal of pediatrics 2015. PMID: 26547399


  70. Sadowska GB, Chen X, Zhang J, Lim YP, Cummings EE, Makeyev O, Besio WG, Gaitanis J, Padbury JF, Banks WA, Stonestreet BS. Interleukin-1β transfer across the blood-brain barrier in the ovine fetus. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015. PMID: 26082012


  71. Liu L, Mao Q, Chu S, Mounayar M, Abdi R, Fodor W, Padbury JF, De Paepe ME. Intranasal versus intraperitoneal delivery of human umbilical cord tissue-derived cultured mesenchymal stromal cells in a murine model of neonatal lung injury. The American journal of pathology 2014. PMID: 25455688


  72. Lester BM, Hawes K, Abar B, Sullivan M, Miller R, Bigsby R, Laptook A, Salisbury A, Taub M, Lagasse LL, Padbury JF. Single-family room care and neurobehavioral and medical outcomes in preterm infants. Pediatrics 2014. PMID: 25246623


  73. Mirza H, Ziegler J, Ford S, Padbury J, Tucker R, Laptook A. Pulmonary hypertension in preterm infants: prevalence and association with bronchopulmonary dysplasia. The Journal of pediatrics 2014. PMID: 25189821


  74. Kobashigawa LC, Xu YC, Padbury JF, Tseng YT, Yano N. Metformin protects cardiomyocyte from doxorubicin induced cytotoxicity through an AMP-activated protein kinase dependent signaling pathway: an in vitro study. PloS one 2014. PMID: 25127116


  75. Lesseur C, Armstrong DA, Paquette AG, Li Z, Padbury JF, Marsit CJ. Maternal obesity and gestational diabetes are associated with placental leptin DNA methylation. American journal of obstetrics and gynecology 2014. PMID: 24954653


  76. Triche EW, Uzun A, DeWan AT, Kurihara I, Liu J, Occhiogrosso R, Shen B, Parker J, Padbury JF. Bioinformatic approach to the genetics of preeclampsia. Obstetrics and gynecology 2014. PMID: 24807322


  77. Stroud LR, Papandonatos GD, Rodriguez D, McCallum M, Salisbury AL, Phipps MG, Lester B, Huestis MA, Niaura R, Padbury JF, Marsit CJ. Maternal smoking during pregnancy and infant stress response: test of a prenatal programming hypothesis. Psychoneuroendocrinology 2014. PMID: 24999830


  78. Moore RG, Hill EK, Horan T, Yano N, Kim K, MacLaughlan S, Lambert-Messerlian G, Tseng YD, Padbury JF, Miller MC, Lange TS, Singh RK. HE4 (WFDC2) gene overexpression promotes ovarian tumor growth. Scientific Reports 2014. PMID: 24389815


  79. Shah BA, Padbury JF. 50 years ago in the Journal of Pediatrics: the behavior of the lower esophageal sphincter in infants and its relationship to gastroesophageal regurgitation. The Journal of pediatrics 2014. PMID: 24359904


  80. Shah BA, Padbury JF. Neonatal sepsis: an old problem with new insights. Virulence 2013. PMID: 24185532


  81. Kawar N, Maclaughlan S, Horan TC, Uzun A, Lange TS, Kim KK, Hopson R, Singh AP, Sidhu PS, Glass KA, Shaw S, Padbury JF, Vorsa N, Arnold LA, Moore RG, Brard L, Singh RK. PT19c, Another Nonhypercalcemic Vitamin D2 Derivative, Demonstrates Antitumor Efficacy in Epithelial Ovarian and Endometrial Cancer Models. Genes & cancer 2013. PMID: 24386512


  82. Marsit CJ, Koestler DC, Watson-Smith D, Boney CM, Padbury JF, Luks F. Developmental genes targeted for epigenetic variation between twin-twin transfusion syndrome children. Clinical epigenetics 2013. PMID: 24090360


  83. Kalkunte SS, Neubeck S, Norris WE, Cheng SB, Kostadinov S, Vu Hoang D, Ahmed A, von Eggeling F, Shaikh Z, Padbury J, Berg G, Olofsson A, Markert UR, Sharma S. Transthyretin is dysregulated in preeclampsia, and its native form prevents the onset of disease in a preclinical mouse model. The American journal of pathology 2013. PMID: 24035612


  84. Appleton AA, Armstrong DA, Lesseur C, Lee J, Padbury JF, Lester BM, Marsit CJ. Patterning in placental 11-B hydroxysteroid dehydrogenase methylation according to prenatal socioeconomic adversity. PloS one 2013. PMID: 24040322


  85. Lesseur C, Armstrong DA, Paquette AG, Koestler DC, Padbury JF, Marsit CJ. Tissue-specific Leptin promoter DNA methylation is associated with maternal and infant perinatal factors. Molecular and cellular endocrinology 2013. PMID: 23911897


  86. Maccani MA, Padbury JF, Lester BM, Knopik VS, Marsit CJ. Placental miRNA expression profiles are associated with measures of infant neurobehavioral outcomes. Pediatric research 2013. PMID: 23783433


  87. Mao Q, Chu S, Ghanta S, Padbury JF, De Paepe ME. Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs. Respiratory research 2013. PMID: 23522153


  88. Saadeh FB, Clark MA, Rogers ML, Linkletter CD, Phipps MG, Padbury JF, Vivier PM. Pregnant and moving: understanding residential mobility during pregnancy and in the first year of life using a prospective birth cohort. Maternal and child health journal 2013. PMID: 22415811


  89. De Paepe ME, Mao Q, Chu S, Padbury JF. Long-term outcome of human cord blood-derived hematopoietic progenitor cells in murine lungs. Experimental lung research 2013. PMID: 23302116


  90. Uzun A, Dewan AT, Istrail S, Padbury JF. Pathway-based genetic analysis of preterm birth. Genomics 2013. PMID: 23298525


  91. Lester BM, Marsit CJ, Conradt E, Bromer C, Padbury JF. Behavioral epigenetics and the developmental origins of child mental health disorders. Journal of developmental origins of health and disease 2012. PMID: 25084292


  92. Yano N, Suzuki D, Endoh M, Zhang W, Xu YC, Padbury JF, Tseng YT. In vitro silencing of the insulin receptor attenuates cellular accumulation of fibronectin in renal mesangial cells. Cell communication and signaling : CCS 2012. PMID: 23061721


  93. Govindaraju A, Uzun A, Robertson L, Atli MO, Kaya A, Topper E, Crate EA, Padbury J, Perkins A, Memili E. Dynamics of microRNAs in bull spermatozoa. Reproductive biology and endocrinology : RB&E 2012. PMID: 22978562


  94. Chen X, Threlkeld SW, Cummings EE, Sadowska GB, Lim YP, Padbury JF, Sharma S, Stonestreet BS. In-vitro validation of cytokine neutralizing antibodies by testing with ovine mononuclear splenocytes. Journal of comparative pathology 2012. PMID: 22819013


  95. Bromer C, Marsit CJ, Armstrong DA, Padbury JF, Lester B. Genetic and epigenetic variation of the glucocorticoid receptor (NR3C1) in placenta and infant neurobehavior. Developmental psychobiology 2012. PMID: 22714792


  96. Bender GJ, Koestler D, Ombao H, McCourt M, Alskinis B, Rubin LP, Padbury JF. Neonatal intensive care unit: predictive models for length of stay. Journal of perinatology : official journal of the California Perinatal Association 2012. PMID: 22678140


  97. Moore RG, Lange TS, Robinson K, Kim KK, Uzun A, Horan TC, Kawar N, Yano N, Chu SR, Mao Q, Brard L, DePaepe ME, Padbury JF, Arnold LA, Brodsky A, Shen TL, Singh RK. Efficacy of a non-hypercalcemic vitamin-D2 derived anti-cancer agent (MT19c) and inhibition of fatty acid synthesis in an ovarian cancer xenograft model. PloS one 2012. PMID: 22509304


  98. Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause PJ, Babesia Testing Investigational Containment Study Group. Preventing transfusion-transmitted babesiosis: preliminary experience of the first laboratory-based blood donor screening program. Transfusion 2012. PMID: 22452654


  99. Marsit CJ, Maccani MA, Padbury JF, Lester BM. Placental 11-beta hydroxysteroid dehydrogenase methylation is associated with newborn growth and a measure of neurobehavioral outcome. PloS one 2012. PMID: 22432047


  100. Uzun A, Sharma S, Padbury J. A bioinformatics approach to preterm birth. American journal of reproductive immunology (New York, N.Y. : 1989) 2012. PMID: 22385126


  101. Uzun A, Laliberte A, Parker J, Andrew C, Winterrowd E, Sharma S, Istrail S, Padbury JF. dbPTB: a database for preterm birth. Database : the journal of biological databases and curation 2012. PMID: 22323062


  102. Marsit CJ, Lambertini L, Maccani MA, Koestler DC, Houseman EA, Padbury JF, Lester BM, Chen J. Placenta-imprinted gene expression association of infant neurobehavior. The Journal of pediatrics 2011. PMID: 22153677


  103. Wilhelm-Benartzi CS, Houseman EA, Maccani MA, Poage GM, Koestler DC, Langevin SM, Gagne LA, Banister CE, Padbury JF, Marsit CJ. In utero exposures, infant growth, and DNA methylation of repetitive elements and developmentally related genes in human placenta. Environmental health perspectives 2011. PMID: 22005006


  104. Banister CE, Koestler DC, Maccani MA, Padbury JF, Houseman EA, Marsit CJ. Infant growth restriction is associated with distinct patterns of DNA methylation in human placentas. Epigenetics 2011. PMID: 21758004


  105. Maccani MA, Padbury JF, Marsit CJ. miR-16 and miR-21 expression in the placenta is associated with fetal growth. PloS one 2011. PMID: 21698265


  106. Ponder KL, Salisbury A, McGonnigal B, Laliberte A, Lester B, Padbury JF. Maternal depression and anxiety are associated with altered gene expression in the human placenta without modification by antidepressant use: implications for fetal programming. Developmental psychobiology 2011. PMID: 21547899


  107. De Paepe ME, Mao Q, Ghanta S, Hovanesian V, Padbury JF. Alveolar epithelial cell therapy with human cord blood-derived hematopoietic progenitor cells. The American journal of pathology 2011. PMID: 21356383


  108. Lester BM, Miller RJ, Hawes K, Salisbury A, Bigsby R, Sullivan MC, Padbury JF. Infant neurobehavioral development. Seminars in perinatology 2011. PMID: 21255702


  109. Padbury JF. Millennium neonatology: building for the future. Introduction. Seminars in perinatology 2011. PMID: 21255700


  110. Robins JC, Marsit CJ, Padbury JF, Sharma SS. Endocrine disruptors, environmental oxygen, epigenetics and pregnancy. Frontiers in bioscience (Elite edition) 2011. PMID: 21196344


  111. McGregor C, Catley C, James A, Padbury J. Next generation neonatal health informatics with Artemis. Studies in health technology and informatics 2011. PMID: 21893725


  112. Kim CR, Sadowska GB, Newton SA, Merino M, Petersson KH, Padbury JF, Stonestreet BS. Na+,K+-ATPase activity and subunit protein expression: ontogeny and effects of exogenous and endogenous steroids on the cerebral cortex and renal cortex of sheep. Reproductive sciences (Thousand Oaks, Calif.) 2010. PMID: 20959645


  113. Maccani MA, Avissar-Whiting M, Banister CE, McGonnigal B, Padbury JF, Marsit CJ. Maternal cigarette smoking during pregnancy is associated with downregulation of miR-16, miR-21, and miR-146a in the placenta. Epigenetics 2010. PMID: 20647767


  114. Kalkunte S, Boij R, Norris W, Friedman J, Lai Z, Kurtis J, Lim KH, Padbury JF, Matthiesen L, Sharma S. Sera from preeclampsia patients elicit symptoms of human disease in mice and provide a basis for an in vitro predictive assay. The American journal of pathology 2010. PMID: 20889559


  115. Sharma S, Stabila J, Pietras L, Singh AR, McGonnigal B, Ernerudh J, Matthiesen L, Padbury JF. Haplotype-dependent differential activation of the human IL-10 gene promoter in macrophages and trophoblasts: implications for placental IL-10 deficiency and pregnancy complications. American journal of reproductive immunology (New York, N.Y. : 1989) 2010. PMID: 20482524


  116. Singh K, Zhang LX, Bendelja K, Heath R, Murphy S, Sharma S, Padbury JF, Lim YP. Inter-alpha inhibitor protein administration improves survival from neonatal sepsis in mice. Pediatric research 2010. PMID: 20520583


  117. Chaaban H, Shin M, Sirya E, Lim YP, Caplan M, Padbury JF. Inter-alpha inhibitor protein level in neonates predicts necrotizing enterocolitis. The Journal of pediatrics 2010. PMID: 20955849


  118. Padbury JF, VanVleet MW, Lester BM. Building for the future of Rhode Island's newborns. Medicine and health, Rhode Island 2010. PMID: 20533720


  119. Chrostowski MK, McGonnigal BG, Stabila JP, Padbury JF. Role of the L-amino acid transporter-1 (LAT-1) in mouse trophoblast cell invasion. Placenta 2010. PMID: 20421131


  120. Tseng A, Stabila J, McGonnigal B, Yano N, Yang MJ, Tseng YT, Davol PA, Lum LG, Padbury JF, Zhao TC. Effect of disruption of Akt-1 of lin(-)c-kit(+) stem cells on myocardial performance in infarcted heart. Cardiovascular research 2010. PMID: 20410290


  121. Mercer JS, Vohr BR, Erickson-Owens DA, Padbury JF, Oh W. Seven-month developmental outcomes of very low birth weight infants enrolled in a randomized controlled trial of delayed versus immediate cord clamping. Journal of perinatology : official journal of the California Perinatal Association 2009. PMID: 19847185


  122. Yano N, Suzuki D, Endoh M, Cao TN, Dahdah JR, Tseng A, Stabila JP, McGonnigal BG, Padbury JF, Tseng YT. High ambient glucose induces angiotensin-independent AT-1 receptor activation, leading to increases in proliferation and extracellular matrix accumulation in MES-13 mesangial cells. The Biochemical journal 2009. PMID: 19604148


  123. Salisbury AL, Ponder KL, Padbury JF, Lester BM. Fetal effects of psychoactive drugs. Clinics in perinatology 2009. PMID: 19732616


  124. Christensen BC, Houseman EA, Marsit CJ, Zheng S, Wrensch MR, Wiemels JL, Nelson HH, Karagas MR, Padbury JF, Bueno R, Sugarbaker DJ, Yeh RF, Wiencke JK, Kelsey KT. Aging and environmental exposures alter tissue-specific DNA methylation dependent upon CpG island context. PLoS genetics 2009. PMID: 19680444


  125. Lester BM, Padbury JF. Third pathophysiology of prenatal cocaine exposure. Developmental neuroscience 2009. PMID: 19372684


  126. Chaaban H, Singh K, Huang J, Siryaporn E, Lim YP, Padbury JF. The role of inter-alpha inhibitor proteins in the diagnosis of neonatal sepsis. The Journal of pediatrics 2009. PMID: 19324226


  127. Chrostowski MK, McGonnigal BG, Stabila JP, Padbury JF. LAT-1 expression in pre- and post-implantation embryos and placenta. Placenta 2009. PMID: 19193433


  128. Murphy SP, Hanna NN, Fast LD, Shaw SK, Berg G, Padbury JF, Romero R, Sharma S. Evidence for participation of uterine natural killer cells in the mechanisms responsible for spontaneous preterm labor and delivery. American journal of obstetrics and gynecology 2008. PMID: 19114277


  129. Fritzell JA, Mao Q, Gundavarapu S, Pasquariello T, Aliotta JM, Ayala A, Padbury JF, De Paepe ME. Fate and effects of adult bone marrow cells in lungs of normoxic and hyperoxic newborn mice. American journal of respiratory cell and molecular biology 2008. PMID: 18988921


  130. Kalkunte S, Lai Z, Tewari N, Chichester C, Romero R, Padbury J, Sharma S. In vitro and in vivo evidence for lack of endovascular remodeling by third trimester trophoblasts. Placenta 2008. PMID: 18775564


  131. Yano N, Tseng A, Zhao TC, Robbins J, Padbury JF, Tseng YT. Temporally controlled overexpression of cardiac-specific PI3Kalpha induces enhanced myocardial contractility--a new transgenic model. American journal of physiology. Heart and circulatory physiology 2008. PMID: 18723766


  132. Yano N, Suzuki D, Endoh M, Tseng A, Stabila JP, McGonnigal BG, Zhao TC, Padbury JF, Tseng YT. Beta-adrenergic receptor mediated protection against doxorubicin-induced apoptosis in cardiomyocytes: the impact of high ambient glucose. Endocrinology 2008. PMID: 18719028


  133. Jegatheesan P, Ianus V, Buchh B, Yoon G, Chorne N, Ewig A, Lin E, Fields S, Moon-Grady A, Tacy T, Milstein J, Schreiber M, Padbury J, Clyman R. Increased indomethacin dosing for persistent patent ductus arteriosus in preterm infants: a multicenter, randomized, controlled trial. The Journal of pediatrics 2008. PMID: 18534218


  134. Haley SA, Zhao T, Zou L, Klysik JE, Padbury JF, Kochilas LK. Forced expression of the cell cycle inhibitor p57Kip2 in cardiomyocytes attenuates ischemia-reperfusion injury in the mouse heart. BMC physiology 2008. PMID: 18312674


  135. Zhao TC, Tseng A, Yano N, Tseng Y, Davol PA, Lee RJ, Lum LG, Padbury JF. Targeting human CD34+ hematopoietic stem cells with anti-CD45 x anti-myosin light-chain bispecific antibody preserves cardiac function in myocardial infarction. Journal of applied physiology (Bethesda, Md. : 1985) 2008. PMID: 18292296


  136. Zhao TC, Cheng G, Zhang LX, Tseng YT, Padbury JF. Inhibition of histone deacetylases triggers pharmacologic preconditioning effects against myocardial ischemic injury. Cardiovascular research 2007. PMID: 17884027


  137. Yano N, Suzuki D, Endoh M, Zhao TC, Padbury JF, Tseng YT. A novel phosphoinositide 3-kinase-dependent pathway for angiotensin II/AT-1 receptor-mediated induction of collagen synthesis in MES-13 mesangial cells. The Journal of biological chemistry 2007. PMID: 17493931


  138. Than NG, Paidas MJ, Mizutani S, Sharma S, Padbury J, Barnea ER. Embryo-placento-maternal interaction and biomarkers: from diagnosis to therapy--a workshop report. Placenta 2007. PMID: 17382999


  139. Yano N, Ianus V, Zhao TC, Tseng A, Padbury JF, Tseng YT. A novel signaling pathway for beta-adrenergic receptor-mediated activation of phosphoinositide 3-kinase in H9c2 cardiomyocytes. American journal of physiology. Heart and circulatory physiology 2007. PMID: 17369456


  140. Lee RJ, Fang Q, Davol PA, Gu Y, Sievers RE, Grabert RC, Gall JM, Tsang E, Yee MS, Fok H, Huang NF, Padbury JF, Larrick JW, Lum LG. Antibody targeting of stem cells to infarcted myocardium. Stem cells (Dayton, Ohio) 2006. PMID: 17138964


  141. Mercer JS, Vohr BR, McGrath MM, Padbury JF, Wallach M, Oh W. Delayed cord clamping in very preterm infants reduces the incidence of intraventricular hemorrhage and late-onset sepsis: a randomized, controlled trial. Pediatrics 2006. PMID: 16585320


  142. Kim CR, Sadowska GB, Petersson KH, Merino M, Sysyn GD, Padbury JF, Stonestreet BS. Effects of postnatal steroids on Na+/K+-ATPase activity and alpha1- and beta1-subunit protein expression in the cerebral cortex and renal cortex of newborn lambs. Reproduction, fertility, and development 2006. PMID: 16737634


  143. Lum LG, Padbury JF, Davol PA, Lee RJ. Virtual reality of stem cell transplantation to repair injured myocardium. Journal of cellular biochemistry 2005. PMID: 15962306


  144. Tseng YT, Yano N, Rojan A, Stabila JP, McGonnigal BG, Ianus V, Wadhawan R, Padbury JF. Ontogeny of phosphoinositide 3-kinase signaling in developing heart: effect of acute beta-adrenergic stimulation. American journal of physiology. Heart and circulatory physiology 2005. PMID: 16006545


  145. Ron NP, Kazianis JA, Padbury JF, Brown CM, McGonnigal BG, Sysyn GD, Sadowska GB, Stonestreet BS. Ontogeny and the effects of corticosteroid pretreatment on aquaporin water channels in the ovine cerebral cortex. Reproduction, fertility, and development 2005. PMID: 15907279


  146. Padbury JF, Diah SK, McGonnigal B, Miller C, Fugere C, Kuzniar M, Thompson NL. Transcriptional regulation of the LAT-1/CD98 light chain. Biochemical and biophysical research communications 2004. PMID: 15120633


  147. Hleb M, Murphy S, Wagner EF, Hanna NN, Sharma N, Park J, Li XC, Strom TB, Padbury JF, Tseng YT, Sharma S. Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes. The Journal of biological chemistry 2004. PMID: 15131122


  148. Zabetian CP, Romero R, Robertson D, Sharma S, Padbury JF, Kuivaniemi H, Kim KS, Kim CH, Köhnke MD, Kranzler HR, Gelernter J, Cubells JF. A revised allele frequency estimate and haplotype analysis of the DBH deficiency mutation IVS1+2T --> C in African- and European-Americans. American journal of medical genetics. Part A 2003. PMID: 14598346


  149. Baek YW, Brokat S, Padbury JF, Pinar H, Hixson DC, Lim YP. Inter-alpha inhibitor proteins in infants and decreased levels in neonatal sepsis. The Journal of pediatrics 2003. PMID: 12915817


  150. Wadhawan R, Tseng YT, Stabila J, McGonnigal B, Sarkar S, Padbury J. Regulation of cardiac beta 1-adrenergic receptor transcription during the developmental transition. American journal of physiology. Heart and circulatory physiology 2003. PMID: 12742828


  151. Tseng YT, Wadhawan R, Stabila JP, McGonnigal BG, Padbury JF. Molecular interactions between glucocorticoid and catecholamine signaling pathways. The Journal of allergy and clinical immunology 2002. PMID: 12464932


  152. Rehan VK, Torday JS, Peleg S, Gennaro L, Vouros P, Padbury J, Rao DS, Reddy GS. 1Alpha,25-dihydroxy-3-epi-vitamin D3, a natural metabolite of 1alpha,25-dihydroxy vitamin D3: production and biological activity studies in pulmonary alveolar type II cells. Molecular genetics and metabolism 2002. PMID: 12175780


  153. Goodwin G, Msall ME, Vohr BR, Rubin LP, Padbury J. Newborn screening: an overview with an update on recent advances. Current problems in pediatric and adolescent health care 2002. PMID: 12024103


  154. Sarkar S, Tsai SW, Nguyen TT, Plevyak M, Padbury JF, Rubin LP. Inhibition of placental 11beta-hydroxysteroid dehydrogenase type 2 by catecholamines via alpha-adrenergic signaling. American journal of physiology. Regulatory, integrative and comparative physiology 2001. PMID: 11705783


  155. McNab TC, Tseng YT, Stabila JP, McGonnigal BG, Padbury JF. Liganded and unliganded steroid receptor modulation of beta 1 adrenergic receptor gene transcription. Pediatric research 2001. PMID: 11641450


  156. Tseng YT, Kopel R, Stabila JP, McGonnigal BG, Nguyen TT, Gruppuso PA, Padbury JF. Beta-adrenergic receptors (betaAR) regulate cardiomyocyte proliferation during early postnatal life. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001. PMID: 11532972


  157. Tseng YT, Stabila JP, Nguyen TT, McGonnigal BG, Waschek JA, Padbury JF. A novel glucocorticoid regulatory unit mediates the hormone responsiveness of the beta1-adrenergic receptor gene. Molecular and cellular endocrinology 2001. PMID: 11476950


  158. Newnham JP, Moss TJ, Padbury JF, Willet KE, Ikegami M, Ervin MG, Sly P, Jobe A. The interactive effects of endotoxin with prenatal glucocorticoids on short-term lung function in sheep. American journal of obstetrics and gynecology 2001. PMID: 11483927


  159. Diah SK, Padbury JF, Campbell WA, Britt D, Thompson NL. Molecular cloning of the rat TA1/LAT-1/CD98 light chain gene promoter. Biochimica et biophysica acta 2001. PMID: 11311938


  160. Thureen PJ, Padbury JF, Hay WW. The effect of maternal hypoaminoacidaemia on placental uptake and transport of amino acids in pregnant sheep. Placenta 2001. PMID: 11170820


  161. Karinski DA, Balkundi D, Rubin LP, Padbury JF. The use of inhaled glucocorticosteroids and recovery from adrenal suppression after systemic steroid use in a VLBW premature infant with BPD: case report and literature discussion. Neonatal network : NN 2000. PMID: 11949271


  162. Padbury JF, McGonnigal B, Tseng YT, Nguyen TT, Stabila JP. Cloning and sequence analysis of the rat norepinephrine transporter promoter. Brain research. Molecular brain research 2000. PMID: 11072103


  163. Jobe AH, Newnham JP, Willet KE, Moss TJ, Gore Ervin M, Padbury JF, Sly P, Ikegami M. Endotoxin-induced lung maturation in preterm lambs is not mediated by cortisol. American journal of respiratory and critical care medicine 2000. PMID: 11069792


  164. Ervin MG, Padbury JF, Polk DH, Ikegami M, Berry LM, Jobe AH. Antenatal glucocorticoids alter premature newborn lamb neuroendocrine and endocrine responses to hypoxia. American journal of physiology. Regulatory, integrative and comparative physiology 2000. PMID: 10956240


  165. Hanna N, Hanna I, Hleb M, Wagner E, Dougherty J, Balkundi D, Padbury J, Sharma S. Gestational age-dependent expression of IL-10 and its receptor in human placental tissues and isolated cytotrophoblasts. Journal of immunology (Baltimore, Md. : 1950) 2000. PMID: 10820249


  166. Tseng YT, Padbury JF. Primer extension methods for determination of beta 1-adrenergic receptor mRNA start sites. Methods in molecular biology (Clifton, N.J.) 2000. PMID: 10685410


  167. Tseng YT, Padbury JF. Transient transfection and adrenergic receptor promoter analysis. Methods in molecular biology (Clifton, N.J.) 2000. PMID: 10685415


  168. Nguyen TT, Tseng YT, McGonnigal B, Stabila JP, Worrell LA, Saha S, Padbury JF. Placental biogenic amine transporters: in vivo function, regulation and pathobiological significance. Placenta 1999. PMID: 9950139


  169. Tseng YT, Stabila J, McGonnigal B, Nguyen TT, Padbury JF. An inverted cAMP response element mediates the cAMP induction of the ovine beta 1-adrenergic receptor gene. Biochemistry and molecular biology international 1998. PMID: 9891845


  170. Padbury JF. Neonatal dopamine pharmacodynamics: lessons from the bedside. The Journal of pediatrics 1998. PMID: 9842029


  171. Berry LM, Padbury J, Novoa-Takara L, Emmanouilides GC. Premature "closing" of the foramen ovale in transposition of the great arteries with intact ventricular septum: rare cause of sudden neonatal death. Pediatric cardiology 1998. PMID: 9568223


  172. Ballard RA, Ballard PL, Cnaan A, Pinto-Martin J, Davis DJ, Padbury JF, Phibbs RH, Parer JT, Hart MC, Mannino FL, Sawai SK. Antenatal thyrotropin-releasing hormone to prevent lung disease in preterm infants. North American Thyrotropin-Releasing Hormone Study Group. Volume 338 of Issue 8. The New England journal of medicine 1998. PMID: 9468465


  173. Tseng YT, Padbury JF. Expression of a pulmonary endothelial norepinephrine transporter. Journal of neural transmission (Vienna, Austria : 1996) 1998. PMID: 9928887


  174. Berg RA, Padbury JF. Sulfoconjugation and renal excretion contribute to the interpatient variation of exogenous catecholamine clearance in critically ill children. Critical care medicine 1997. PMID: 9233755


  175. Berry LM, Polk DH, Ikegami M, Jobe AH, Padbury JF, Ervin MG. Preterm newborn lamb renal and cardiovascular responses after fetal or maternal antenatal betamethasone. The American journal of physiology 1997. PMID: 9227616


  176. Billings KR, Kerner MM, Padbury JF, Abemayor E. Laryngotracheal stenosis in a case of Pena-Shokier syndrome. American journal of otolaryngology 1997. PMID: 9164631


  177. Padbury JF, Tseng YT, McGonnigal B, Penado K, Stephan M, Rudnick G. Placental biogenic amine transporters: cloning and expression. Brain research. Molecular brain research 1997. PMID: 9105686


  178. Bzoskie L, Yen J, Tseng YT, Blount L, Kashiwai K, Padbury JF. Human placental norepinephrine transporter mRNA: expression and correlation with fetal condition at birth. Placenta 1997. PMID: 9089783


  179. Derks JB, Giussani DA, Jenkins SL, Wentworth RA, Visser GH, Padbury JF, Nathanielsz PW. A comparative study of cardiovascular, endocrine and behavioural effects of betamethasone and dexamethasone administration to fetal sheep. The Journal of physiology 1997. PMID: 9061651


  180. Jobe AH, Ikegami M, Padbury J, Polk DH, Korirnilli A, Gonzales LW, Ballard PL. Combined effects of fetal beta agonist stimulation and glucocorticoids on lung function of preterm lambs. Volume 72 of Issue 5. Biology of the neonate 1997. PMID: 9395841


  181. Bzoskie I, Blount I, Kashiwai K, Humme J, Padbury JF. Placental norepinephrine transporter development in the ovine fetus. Placenta 1997. PMID: 9032811


  182. Bzoskie L, Blount L, Kashiwai K, Humme J, Padbury JF. The contribution of transporter-dependent uptake to fetal catecholamine clearance. Biology of the neonate 1997. PMID: 9057993


  183. Walther FJ, Mehta EI, Padbury JF. Lung CuZn-superoxide dismutase and catalase gene expression in premature rabbits treated intratracheally with antioxidant-surfactant liposomes. Biochemical and molecular medicine 1996. PMID: 8986640


  184. Ervin MG, Berry LM, Ikegami M, Jobe AH, Padbury JF, Polk DH. Single dose fetal betamethasone administration stabilizes postnatal glomerular filtration rate and alters endocrine function in premature lambs. Pediatric research 1996. PMID: 8910927


  185. Jobe AH, Polk DH, Ervin MG, Padbury JF, Rebello CM, Ikegami M. Preterm betamethasone treatment of fetal sheep: outcome after term delivery. Journal of the Society for Gynecologic Investigation 1996. PMID: 8796837


  186. Downs T, Padbury J, Blount L, Kashiwai K, Chan K. Ovine fetal-placental cocaine pharmacokinetics during continuous cocaine infusion. Journal of the Society for Gynecologic Investigation 1996. PMID: 8796829


  187. Padbury JF, Ervin MG, Polk DH. Extrapulmonary effects of antenatally administered steroids. The Journal of pediatrics 1996. PMID: 8636806


  188. Padbury JF, Polk DH, Ervin MG, Berry LM, Ikegami M, Jobe AH. Postnatal cardiovascular and metabolic responses to a single intramuscular dose of betamethasone in fetal sheep born prematurely by cesarean section. Pediatric research 1995. PMID: 8552438


  189. Tseng YT, Waschek JA, Padbury JF. Functional analysis of the 5' flanking sequence in the ovine beta 1-adrenergic receptor gene. Biochemical and biophysical research communications 1995. PMID: 7487998


  190. Bzoskie L, Blount L, Kashiwai K, Tseng YT, Hay WW, Padbury JF. Placental norepinephrine clearance: in vivo measurement and physiological role. The American journal of physiology 1995. PMID: 7631769


  191. Padbury JF, Tseng YT, Waschek JA. Transcription initiation is localized to a TATAless region in the ovine beta 1 adrenergic receptor gene. Biochemical and biophysical research communications 1995. PMID: 7779093


  192. Tseng YT, Tucker MA, Kashiwai KT, Waschek JA, Padbury JF. Regulation of beta 1-adrenoceptors by glucocorticoids and thyroid hormones in fetal sheep. European journal of pharmacology 1995. PMID: 7621909


  193. Padbury JF, Tseng YT, Waschek JA. A cloning strategy for G-protein-coupled hormone receptors: the ovine beta 1-adrenergic receptor. Reproduction, fertility, and development 1995. PMID: 8606964


  194. Stein HM, Martinez A, Oyama K, Blount L, Padbury JF. Effect of corticosteroids on free and sulfoconjugated catecholamines at birth in premature newborn sheep. The American journal of physiology 1995. PMID: 7840178


  195. Agata Y, Hiraishi S, Misawa H, Han JH, Oguchi K, Horiguchi Y, Fujino N, Takeda N, Padbury JF. Hemodynamic adaptations at birth and neonates delivered vaginally and by Cesarean section. Biology of the neonate 1995. PMID: 8721884


  196. Newnham JP, Polk DH, Kelly RW, Padbury JF, Evans SF, Ikegami M, Jobe AH. Catecholamine response to ultrasonographically guided percutaneous blood sampling in fetal sheep. American journal of obstetrics and gynecology 1994. PMID: 8059826


  197. Stein HM, Martinez A, Blount L, Oyama K, Padbury JF. The effects of corticosteroids and thyrotropin-releasing hormone on newborn adaptation and sympathoadrenal mechanisms in preterm sheep. American journal of obstetrics and gynecology 1994. PMID: 8030694


  198. Ogundipe OA, Kullama LK, Stein H, Nijland MJ, Ervin MG, Padbury J, Ross MG. Fetal endocrine and renal responses to in utero ventilation and umbilical cord occlusion. American journal of obstetrics and gynecology 1993. PMID: 8267050


  199. Stein H, Oyama K, Martinez A, Chappell B, Padbury J. Plasma epinephrine appearance and clearance rates in fetal and newborn sheep. The American journal of physiology 1993. PMID: 8238443


  200. Berg RA, Padbury JF, Donnerstein RL, Klewer SE, Hutter JJ. Dobutamine pharmacokinetics and pharmacodynamics in normal children and adolescents. The Journal of pharmacology and experimental therapeutics 1993. PMID: 8510005


  201. Berg RA, Donnerstein RL, Padbury JF. Dobutamine infusions in stable, critically ill children: pharmacokinetics and hemodynamic actions. Critical care medicine 1993. PMID: 8482088


  202. Stein HM, Oyama K, Martinez A, Chappell BA, Buhl E, Blount L, Padbury JF. Effects of corticosteroids in preterm sheep on adaptation and sympathoadrenal mechanisms at birth. The American journal of physiology 1993. PMID: 8388639


  203. Chan K, Dodd PA, Day L, Kullama L, Ervin MG, Padbury J, Ross MG. Fetal catecholamine, cardiovascular, and neurobehavioral responses to cocaine. American journal of obstetrics and gynecology 1992. PMID: 1471676


  204. Ballard PL, Ballard RA, Creasy RK, Padbury J, Polk DH, Bracken M, Moya FR, Gross I. Plasma thyroid hormones and prolactin in premature infants and their mothers after prenatal treatment with thyrotropin-releasing hormone. Volume 32 of Issue 6. Pediatric research 1992. PMID: 1287557


  205. Oyama K, Padbury J, Martinez A, Chappell B, Stein H, Humme J. Effects of fetal growth retardation on the development of central and peripheral catecholaminergic pathways in the sheep. Journal of developmental physiology 1992. PMID: 1339139


  206. Oyama K, Padbury J, Chappell B, Martinez A, Stein H, Humme J. Single umbilical artery ligation-induced fetal growth retardation: effect on postnatal adaptation. The American journal of physiology 1992. PMID: 1415539


  207. Savich RD, Guerra FA, Lee CC, Padbury JF, Kitterman JA. Effects of acute oligohydramnios on respiratory system of fetal sheep. Journal of applied physiology (Bethesda, Md. : 1985) 1992. PMID: 1399988


  208. Sapien R, Stein H, Padbury JF, Thio S, Hodge D. Intraosseous versus intravenous epinephrine infusions in lambs: pharmacokinetics and pharmacodynamics. Pediatric emergency care 1992. PMID: 1513725


  209. Oyama K, Padbury J, Martinez A, Chappell B, Stein H, Blount L, Buhl E. Free and sulfoconjugated catecholamine responses at birth in newborn sheep. The American journal of physiology 1992. PMID: 1636697


  210. Habib DM, Padbury JF, Anas NG, Perkin RM, Minegar C. Dobutamine pharmacokinetics and pharmacodynamics in pediatric intensive care patients. Critical care medicine 1992. PMID: 1572184


  211. Martinez AM, Padbury JF, Barberie LM, Burnell EE, Thio S. Elevated plasma Met-enkephalin levels in the human newborn are a poor indicator of perinatal stress. American journal of obstetrics and gynecology 1992. PMID: 1595798


  212. Stein HM, Oyama K, Sapien R, Chappell BA, Padbury JF. Prolonged beta-agonist infusion does not induce desensitization or down-regulation of beta-adrenergic receptors in newborn sheep. Pediatric research 1992. PMID: 1351281


  213. Ballard RA, Ballard PL, Creasy RK, Padbury J, Polk DH, Bracken M, Moya FR, Gross I. Respiratory disease in very-low-birthweight infants after prenatal thyrotropin-releasing hormone and glucocorticoid. TRH Study Group. Volume 339 of Issue 8792. Lancet (London, England) 1992. PMID: 1346877


  214. Martinez AM, Padbury JF, Thio S. Dobutamine pharmacokinetics and cardiovascular responses in critically ill neonates. Pediatrics 1992. PMID: 1728020


  215. Collins JW, Hoppe M, Brown K, Edidin DV, Padbury J, Ogata ES. A controlled trial of insulin infusion and parenteral nutrition in extremely low birth weight infants with glucose intolerance. The Journal of pediatrics 1991. PMID: 1904090


  216. Martinez A, Padbury J, Chappell B, Habib D, Thio S, Burnell E. Maturational changes in expression of enkephalin peptides in adrenal and extra-adrenal tissue of fetal and adult rabbits. Brain research bulletin 1991. PMID: 1933413


  217. Chappell B, Padbury J, Martinez A, Habib D, Stein H, Oyama K. Cardiovascular effects of SKF 104078 in lambs. Developmental pharmacology and therapeutics 1991. PMID: 1687457


  218. Habib DM, Padbury JF, Martinez AM, Chappell BA, Thio SL, Burnell EE. Neonatal adaptation: cardiac adrenergic effector mechanisms after birth in newborn sheep. Pediatric research 1991. PMID: 1848003


  219. Ervin MG, Castro R, Sherman DJ, Ross MG, Padbury JF, Leake RD, Fisher DA. Ovine fetal renal and hormonal responses to changes in plasma epinephrine. The American journal of physiology 1991. PMID: 1825160


  220. Martinez AM, Padbury JF, Burnell EE, Thio SL. Plasma methionine enkephalin levels in the human newborn at birth. Biology of the neonate 1991. PMID: 1932384


  221. Chappell BA, Padbury JF, Habib DM, Martinez AM, Thio SL, Burnell EE, Humme JA. Pulmonary clearance of norepinephrine in lambs. Pediatric research 1991. PMID: 2000265


  222. Harwell CM, Padbury JF, Anand RS, Martinez AM, Ipp E, Thio SL, Burnell EE. Fetal catecholamine responses to maternal hypoglycemia. The American journal of physiology 1990. PMID: 2260723


  223. Padbury JF, Agata Y, Baylen BG, Ludlow JK, Polk DH, Habib DM, Martinez AM. Pharmacokinetics of dopamine in critically ill newborn infants. The Journal of pediatrics 1990. PMID: 2391608


  224. Martinez AM, Padbury JF, Humme JA, Evans CW, Shames L. Plasma catecholamines and their physiologic thresholds during the first ten days of life in sheep. Journal of developmental physiology 1990. PMID: 2277179


  225. Martinez AM, Padbury JF, Burnell EE, Thio SL, Humme J. The effects of hypoxia on (methionine) enkephalin peptide and catecholamine release in fetal sheep. Pediatric research 1990. PMID: 2296472


  226. Padbury JF. Functional maturation of the adrenal medulla and peripheral sympathetic nervous system. Bailliere's clinical endocrinology and metabolism 1989. PMID: 2698151


  227. Baylen BG, Agata Y, Padbury JF, Ikegami M, Jobe AH, Emmanouilides GC. Hemodynamic and neuroendocrine adaptations of the preterm lamb left ventricle to acutely increased afterload. Pediatric research 1989. PMID: 2552388


  228. Padbury JF, Martinez AM, Thio SL, Burnell EE, Humme JA. Free and sulfoconjugated catecholamine responses to hypoxia in fetal sheep. The American journal of physiology 1989. PMID: 2504049


  229. Ervin MG, Padbury JF, Ross MG, Leake RD, Fisher DA. Developmental changes in adrenergic regulation of fetal arginine vasopressin secretion. The American journal of physiology 1989. PMID: 2923207


  230. Padbury JF, Habib DM, Martinez AM. Thresholds for the physiologic effects of adrenergic agents: a methodologic appraisal. Developmental pharmacology and therapeutics 1989. PMID: 2576531


  231. Martinez A, Padbury J, Shames L, Evans C, Humme J. Naloxone potentiates epinephrine release during hypoxia in fetal sheep: dose response and cardiovascular effects. Pediatric research 1988. PMID: 3374988


  232. Padbury JF, Martinez AM. Sympathoadrenal system activity at birth: integration of postnatal adaptation. Seminars in perinatology 1988. PMID: 3293227


  233. Clyman RI, Teitel D, Padbury J, Roman C, Mauray F. The role of beta-adrenoreceptor stimulation and contractile state in the preterm lamb's response to altered ductus arteriosus patency. Pediatric research 1988. PMID: 2832817


  234. Padbury JF, Agata Y, Polk DH, Wang DL, Lam RW, Callegari CC. Catecholamine and endorphin responses to delivery in term and preterm lambs. Developmental pharmacology and therapeutics 1988. PMID: 2968232


  235. Padbury J, Agata Y, Ludlow J, Ikegami M, Baylen B, Humme J. Effect of fetal adrenalectomy on catecholamine release and physiologic adaptation at birth in sheep. The Journal of clinical investigation 1987. PMID: 3654971


  236. Padbury JF, Agata Y, Polk DH, Wang DL, Callegari CC. Neonatal adaptation: naloxone increases the catecholamine surge at birth. Pediatric research 1987. PMID: 3037473


  237. Polk DH, Callegari CC, Newnham J, Padbury JF, Reviczky A, Fisher DA, Klein AH. Effect of fetal thyroidectomy on newborn thermogenesis in lambs. Pediatric research 1987. PMID: 3588081


  238. Padbury JF, Ludlow JK, Ervin MG, Jacobs HC, Humme JA. Thresholds for physiological effects of plasma catecholamines in fetal sheep. The American journal of physiology 1987. PMID: 3565562


  239. Polk DH, Ervin MG, Padbury JF, Lam RW, Reviczky AL, Fisher DA. Epidermal growth factor acts as a corticotropin-releasing factor in chronically catheterized fetal lambs. The Journal of clinical investigation 1987. PMID: 3029180


  240. Padbury JF, Agata Y, Baylen BG, Ludlow JK, Polk DH, Goldblatt E, Pescetti J. Dopamine pharmacokinetics in critically ill newborn infants. The Journal of pediatrics 1987. PMID: 3806305


  241. Agata Y, Padbury JF, Ludlow JK, Polk DH, Humme JA. The effect of chemical sympathectomy on catecholamine release at birth. Pediatric research 1986. PMID: 3099254


  242. Padbury JF, Lam RW, Polk DH, Newnham JP, Lakshmanan J, Fisher DA. Autoimmune sympathectomy in fetal rabbits. Journal of developmental physiology 1986. PMID: 3794227


  243. Padbury JF, Ludlow JK, Humme JA, Agata Y. Metabolic clearance and plasma appearance rates of catecholamines in preterm and term fetal sheep. Pediatric research 1986. PMID: 3774414


  244. Venkatesh N, Padbury JF, Singh BN. Effects of amiodarone and desethylamiodarone on rabbit myocardial beta-adrenoceptors and serum thyroid hormones--absence of relationship to serum and myocardial drug concentrations. Journal of cardiovascular pharmacology 1986. PMID: 2429101


  245. Lakshmanan J, Padbury J, Macaso T, Wang D, Beri U, Fisher DA. Involvement of developing sympathetic nervous system in thyroxine-mediated submandibular gland nerve growth factor and epidermal growth factor responses. Pediatric research 1986. PMID: 3085059


  246. Newnham JP, Lam RW, Hobel CJ, Padbury JF, Polk DH, Fisher DA. Differential response of ovine placental lactogen levels in maternal and fetal circulations following single umbilical artery ligation in fetal sheep. Placenta 1986. PMID: 3703833


  247. Padbury JF, Klein AH, Polk DH, Lam RW, Hobel C, Fisher DA. Effect of thyroid status on lung and heart beta-adrenergic receptors in fetal and newborn sheep. Developmental pharmacology and therapeutics 1986. PMID: 3004849


  248. Padbury JF, Polk DH, Newnham JP, Lam RW. Neonatal adaptation: greater sympathoadrenal response in preterm than full-term fetal sheep at birth. The American journal of physiology 1985. PMID: 3985142


  249. Newnham JP, Marshall CL, Padbury JF, Lam RW, Hobel CJ, Fisher DA. Fetal catecholamine release with preterm delivery. American journal of obstetrics and gynecology 1984. PMID: 6465254


  250. Klein AH, Reviczky A, Padbury JF. Thyroid hormones augment catecholamine-stimulated brown adipose tissue thermogenesis in the ovine fetus. Endocrinology 1984. PMID: 6323128


  251. Padbury JF, Jacobs HC, Lam RW, Conaway D, Jobe AH, Fisher DA. [Adrenal epinephrine and the regulation of pulmonary surfactant release in neonatal rabbits]. Experimental lung research 1984. PMID: 6549291


  252. Klein AH, Reviczky A, Padbury JF, Fisher DA. Effect of changes in thyroid status on tissue respiration in fetal and newborn sheep. The American journal of physiology 1983. PMID: 6305203


  253. Klein AH, Reviczky A, Chou P, Padbury J, Fisher DA. Development of brown adipose tissue thermogenesis in the ovine fetus and newborn. Endocrinology 1983. PMID: 6403332


  254. Padbury JF, Lam RW, Hobel CJ, Fisher DA. Identification and partial purification of phenylethanolamine N-methyl transferase in the developing ovine lung. Pediatric research 1983. PMID: 6856397


  255. Jobe A, Ikegami M, Glatz T, Yoshida Y, Diakomanolis E, Padbury J. Saturated phosphatidylcholine secretion and the effect of natural surfactant on premature and term lambs ventilated for 2 days. Experimental lung research 1983. PMID: 6552978


  256. Padbury JF, Hobel CJ, Gonzalez FA, Fisher DA. Ontogenesis and sex differences in rabbit fetal adrenal phenylethanolamine N-methyltransferase. Biology of the neonate 1983. PMID: 6871292


  257. Padbury JF, Roberman B, Oddie TH, Hobel CJ, Fisher DA. Fetal catecholamine release in response to labor and delivery. Obstetrics and gynecology 1982. PMID: 6815598


  258. Padbury JF, Diakomanolis ES, Hobel CJ, Perelman A, Fisher DA. Neonatal adaptation: sympatho-adrenal response to umbilical cord cutting. Pediatric research 1981. PMID: 7322667


  259. Padbury JF, Diakomanolis ES, Lam RW, Hobel CJ, Fisher DA. Ontogenesis of tissue catecholamines in fetal and neonatal rabbits. Journal of developmental physiology 1981. PMID: 7338610


  260. Padbury JF, Hobel CJ, Lam RW, Fisher DA. Sex differences in lung and adrenal neurosympathetic development in rabbits. American journal of obstetrics and gynecology 1981. PMID: 6269430


  261. Padbury JF, Hobel CJ, Diakomanolis ES, Lam RW, Fisher DA. Ontogenesis of beta-adrenergic receptors in the ovine placenta. American journal of obstetrics and gynecology 1981. PMID: 6110339


  262. Jobe A, Ikegami M, Glatz T, Yoshida Y, Diakomanolis E, Padbury J. Duration and characteristics of treatment of premature lambs with natural surfactant. The Journal of clinical investigation 1981. PMID: 6780608